Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Nasopharyngeal Diseases D009302 2 associated lipids
Myelitis, Transverse D009188 1 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Multiple Myeloma D009101 13 associated lipids
Mitral Valve Stenosis D008946 3 associated lipids
Meningoencephalitis D008590 4 associated lipids
Lymphogranuloma Venereum D008219 4 associated lipids
Lymphangitis D008205 4 associated lipids
Lymphadenitis D008199 8 associated lipids
Lyme Disease D008193 5 associated lipids
Lung Diseases, Parasitic D008174 2 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Lung Diseases D008171 37 associated lipids
Long QT Syndrome D008133 10 associated lipids
Leprosy D007918 8 associated lipids
Leishmaniasis, Mucocutaneous D007897 1 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Keratosis D007642 9 associated lipids
Keratitis D007634 7 associated lipids
Inflammation D007249 119 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Immunologic Deficiency Syndromes D007153 8 associated lipids
Hypotension D007022 41 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Hyperglycemia D006943 21 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Hoarseness D006685 2 associated lipids
HIV Seropositivity D006679 15 associated lipids
Herpes Genitalis D006558 2 associated lipids
Hernia, Hiatal D006551 3 associated lipids
Hemolysis D006461 131 associated lipids
Heartburn D006356 2 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Hearing Disorders D006311 10 associated lipids
Haemophilus Infections D006192 3 associated lipids
Granuloma Inguinale D006100 2 associated lipids
Gonorrhea D006069 7 associated lipids
Gingival Hyperplasia D005885 3 associated lipids
Giardiasis D005873 3 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Furunculosis D005667 2 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Fever of Unknown Origin D005335 3 associated lipids
Fever D005334 35 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Clarithro- and azithromycin--better erythromycins? 1991 Drug Ther Bull pmid:1665125
Young LS et al. Azithromycin for treatment of Mycobacterium avium-intracellulare complex infection in patients with AIDS. 1991 Lancet pmid:1682544
Foulds G et al. The effects of an antacid or cimetidine on the serum concentrations of azithromycin. 1991 J Clin Pharmacol pmid:1849152
Edelstein PH and Edelstein MA In vitro activity of azithromycin against clinical isolates of Legionella species. 1991 Antimicrob. Agents Chemother. pmid:1849708
Neu HC Clinical microbiology of azithromycin. 1991 Am. J. Med. pmid:1656736
Stamm WE Azithromycin in the treatment of uncomplicated genital chlamydial infections. 1991 Am. J. Med. pmid:1656737
Hooton TM A comparison of azithromycin and penicillin V for the treatment of streptococcal pharyngitis. 1991 Am. J. Med. pmid:1656738
Johnson RB The role of azalide antibiotics in the treatment of Chlamydia. 1991 Am. J. Obstet. Gynecol. pmid:1645503
Goldman RC et al. Role of protonated and neutral forms of macrolides in binding to ribosomes from gram-positive and gram-negative bacteria. 1990 Antimicrob. Agents Chemother. pmid:2159256
Gladue RP and Snider ME Intracellular accumulation of azithromycin by cultured human fibroblasts. 1990 Antimicrob. Agents Chemother. pmid:2168141
Capobianco JO and Goldman RC Erythromycin and azithromycin transport into Haemophilus influenzae ATCC 19418 under conditions of depressed proton motive force (delta mu H). 1990 Antimicrob. Agents Chemother. pmid:2178338
Gorby GL and McGee ZA Antimicrobial interference with bacterial mechanisms of pathogenicity: effect of sub-MIC azithromycin on gonococcal piliation and attachment to human epithelial cells. 1990 Antimicrob. Agents Chemother. pmid:1982402
Goldman RC and Capobianco JO Role of an energy-dependent efflux pump in plasmid pNE24-mediated resistance to 14- and 15-membered macrolides in Staphylococcus epidermidis. 1990 Antimicrob. Agents Chemother. pmid:1963291
Børsum T et al. Chlamydia trachomatis: in vitro susceptibility of genital and ocular isolates to some quinolones, amoxicillin and azithromycin. 1990 Chemotherapy pmid:1963393
Pascual A et al. Effect of azithromycin, roxithromycin and erythromycin on human polymorphonuclear leukocyte function against Staphylococcus aureus. 1990 Chemotherapy pmid:1963394
Ravdin JI and Skilogiannis J In vitro susceptibilities of Entamoeba histolytica to azithromycin, CP-63,956, erythromycin, and metronidazole. 1989 Antimicrob. Agents Chemother. pmid:2548442
Gladue RP et al. In vitro and in vivo uptake of azithromycin (CP-62,993) by phagocytic cells: possible mechanism of delivery and release at sites of infection. 1989 Antimicrob. Agents Chemother. pmid:2543276
Bermudez LE and Young LS Activities of amikacin, roxithromycin, and azithromycin alone or in combination with tumor necrosis factor against Mycobacterium avium complex. 1988 Antimicrob. Agents Chemother. pmid:2847644
Araujo FG et al. Azithromycin, a macrolide antibiotic with potent activity against Toxoplasma gondii. 1988 Antimicrob. Agents Chemother. pmid:2840017
Yourassowsky E et al. Rate of bactericidal activity for Branhamella catarrhalis of a new macrolide, CP-62,993, compared with that of amoxicillin-clavulanic acid. 1988 Chemotherapy pmid:2843324