Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Lück PC and Steinert M | [Pathogenesis, diagnosis and therapy of Legionella infections]. | 2006 | Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz | pmid:16596363 |
Amory JK et al. | Clinical problem-solving. A jaundiced eye. | 2006 | N. Engl. J. Med. | pmid:16598049 |
Brkljacić N et al. | Stevens-Johnson syndrome as an unusual adverse effect of azithromycin. | 2006 | Acta Dermatovenerol Croat | pmid:16603101 |
Felstead SJ and Daniel R | Short-course treatment of sinusitis and other upper respiratory tract infections with azithromycin: a comparison with erythromycin and amoxycillin. European Azithromycin Study Group. | 1991 Sep-Oct | J. Int. Med. Res. | pmid:1660823 |
Daniel R | Simplified treatment of acute lower respiratory tract infection with azithromycin: a comparison with erythromycin and amoxycillin. European Azithromycin Study Group. | 1991 Sep-Oct | J. Int. Med. Res. | pmid:1660824 |
Fairgrieve WT et al. | Concentrations of erythromycin and azithromycin in mature Chinook salmon Oncorhynchus tshawytscha after intraperitoneal injection, and in their progeny. | 2006 | Dis. Aquat. Org. | pmid:16610588 |
Asbel LE et al. | School-based screening for Chlamydia trachomatis and Neisseria gonorrhoeae among Philadelphia public high school students. | 2006 | Sex Transm Dis | pmid:16614587 |
Sevillano D et al. | Azithromycin iv pharmacodynamic parameters predicting Streptococcus pneumoniae killing in epithelial lining fluid versus serum: an in vitro pharmacodynamic simulation. | 2006 | J. Antimicrob. Chemother. | pmid:16617063 |
Brook I and Hausfeld JN | Effect of telithromycin and azithromycin on nasopharyngeal bacterial flora in patients with acute maxillary sinusitis. | 2006 | Arch. Otolaryngol. Head Neck Surg. | pmid:16618915 |
Barr BS | Rhodococcus equi pneumonia in a foal. | 2006 | Vet. Clin. North Am. Equine Pract. | pmid:16627120 |
Stuhne-Sekalec L et al. | Liposomes as carriers of macrolides: preferential association of erythromycin A and azithromycin with liposomes of phosphatidylglycerol containing unsaturated fatty acid(s). | 1991 Apr-Jun | J Microencapsul | pmid:1662717 |
Wilms EB et al. | Pharmacokinetics of azithromycin in plasma, blood, polymorphonuclear neutrophils and sputum during long-term therapy in patients with cystic fibrosis. | 2006 | Ther Drug Monit | pmid:16628134 |
Wareham DW and Bean DC | In-vitro activity of polymyxin B in combination with imipenem, rifampicin and azithromycin versus multidrug resistant strains of Acinetobacter baumannii producing OXA-23 carbapenemases. | 2006 | Ann. Clin. Microbiol. Antimicrob. | pmid:16630352 |
Daniel R | Azithromycin, erythromycin and cloxacillin in the treatment of infections of skin and associated soft tissues. European Azithromycin Study Group. | 1991 Nov-Dec | J. Int. Med. Res. | pmid:1663466 |
Ball AP | Azithromycin: an interim analysis. | 1991 Nov-Dec | J. Int. Med. Res. | pmid:1663467 |
Miedinger D | [Dysuria and urethral discharge after travel abroad]. | 2006 | Praxis (Bern 1994) | pmid:16640179 |
Nalca Y et al. | Quorum-sensing antagonistic activities of azithromycin in Pseudomonas aeruginosa PAO1: a global approach. | 2006 | Antimicrob. Agents Chemother. | pmid:16641435 |
Asgrimsson V et al. | Novel effects of azithromycin on tight junction proteins in human airway epithelia. | 2006 | Antimicrob. Agents Chemother. | pmid:16641453 |
O'Farrell N et al. | Periodic presumptive treatment for cervical infections in service women in 3 border provinces of Laos. | 2006 | Sex Transm Dis | pmid:16645552 |
Plana MT et al. | Toxic catatonia secondary to azithromycin. | 2006 | J Clin Psychiatry | pmid:16649839 |
Clarithro- and azithromycin--better erythromycins? | 1991 | Drug Ther Bull | pmid:1665125 | |
Amer A and Fischer H | Azithromycin does not cure pityriasis rosea. | 2006 | Pediatrics | pmid:16651327 |
Pedro-Botet L and Yu VL | Legionella: macrolides or quinolones? | 2006 | Clin. Microbiol. Infect. | pmid:16669926 |
Bermudez LE et al. | Stimulation with cytokines enhances penetration of azithromycin into human macrophages. | 1991 | Antimicrob. Agents Chemother. | pmid:1667256 |
Mikamo H et al. | [Prevalence and treatment of pharyngeal Chlamydia trachomatis infections]. | 2006 | Jpn J Antibiot | pmid:16673581 |
Atasoy M et al. | A case of early onset confluent and reticulated papillomatosis with an unusual localization. | 2006 | J. Dermatol. | pmid:16674793 |
Rehg JE | Anti-cryptosporidial activity of macrolides in immunosuppressed rats. | 1991 Nov-Dec | J. Protozool. | pmid:1667930 |
Kimata I et al. | Chemotherapeutic effect of azithromycin and lasalocid on Cryptosporidium infection in mice. | 1991 Nov-Dec | J. Protozool. | pmid:1667931 |
Zhang H et al. | Impact of oral azithromycin on recurrence of trachomatous trichiasis in Nepal over 1 year. | 2006 | Br J Ophthalmol | pmid:16687452 |
Ivetić Tkalcević V et al. | Anti-inflammatory activity of azithromycin attenuates the effects of lipopolysaccharide administration in mice. | 2006 | Eur. J. Pharmacol. | pmid:16698012 |
Giles DK et al. | Ultrastructural analysis of chlamydial antigen-containing vesicles everting from the Chlamydia trachomatis inclusion. | 2006 | Microbes Infect. | pmid:16698305 |
Konstantinopoulos PA et al. | Babesiosis masquerading as recurrent immune thrombocytopenic purpura in a splenectomized patient. | 2006 | Ann. Hematol. | pmid:16705453 |
Moon JE et al. | Efficacy of macrolides and telithromycin against leptospirosis in a hamster model. | 2006 | Antimicrob. Agents Chemother. | pmid:16723556 |
Bogdanovich T et al. | Activities of ceftobiprole, a novel broad-spectrum cephalosporin, against Haemophilus influenzae and Moraxella catarrhalis. | 2006 | Antimicrob. Agents Chemother. | pmid:16723565 |
Kosowska-Shick K et al. | Antipneumococcal activity of DW-224a, a new quinolone, compared to those of eight other agents. | 2006 | Antimicrob. Agents Chemother. | pmid:16723567 |
Zhanel GG et al. | Mutant prevention concentrations of levofloxacin alone and in combination with azithromycin, ceftazidime, colistin (Polymyxin E), meropenem, piperacillin-tazobactam, and tobramycin against Pseudomonas aeruginosa. | 2006 | Antimicrob. Agents Chemother. | pmid:16723591 |
Petrini B | Mycobacterium abscessus: an emerging rapid-growing potential pathogen. | 2006 | APMIS | pmid:16725007 |
Enders M et al. | Antimicrobial resistance of Neisseria gonorrhoeae isolates from the Stuttgart and Heidelberg areas of southern Germany. | 2006 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:16733613 |
Hodge S et al. | Azithromycin increases phagocytosis of apoptotic bronchial epithelial cells by alveolar macrophages. | 2006 | Eur. Respir. J. | pmid:16737992 |
Verleden GM et al. | Azithromycin reduces airway neutrophilia and interleukin-8 in patients with bronchiolitis obliterans syndrome. | 2006 | Am. J. Respir. Crit. Care Med. | pmid:16741151 |
Sultana N et al. | Degradation studies of azithromycin and its spectrophotometric determination in pharmaceutical dosage forms. | 2006 | Pak J Pharm Sci | pmid:16751118 |
Bryant KA et al. | Measures to control an outbreak of pertussis in a neonatal intermediate care nursery after exposure to a healthcare worker. | 2006 | Infect Control Hosp Epidemiol | pmid:16755471 |
Giugliani C et al. | Feasibility of azithromycin prophylaxis during a pertussis outbreak among healthcare workers in a university hospital in Paris. | 2006 | Infect Control Hosp Epidemiol | pmid:16755485 |
Saha D et al. | Single-dose azithromycin for the treatment of cholera in adults. | 2006 | N. Engl. J. Med. | pmid:16760445 |
Guerrant RL | Cholera--still teaching hard lessons. | 2006 | N. Engl. J. Med. | pmid:16760452 |
Dimitrijević A et al. | Micronucleus frequency in women with genital Chlamydia Trachomatis infection before and after therapy. | 2006 | Mutat. Res. | pmid:16777475 |
Esposito S et al. | Acute tonsillopharyngitis associated with atypical bacterial infection in children: natural history and impact of macrolide therapy. | 2006 | Clin. Infect. Dis. | pmid:16779748 |
An N et al. | [Severe liver damage caused by intravenous infusion of azithromycin in a case]. | 2006 | Zhonghua Er Ke Za Zhi | pmid:16780660 |
Alou L et al. | A pharmacodynamic approach to antimicrobial activity in serum and epithelial lining fluid against in vivo-selected Streptococcus pneumoniae mutants and association with clinical failure in pneumonia. | 2006 | J. Antimicrob. Chemother. | pmid:16782744 |
Falcó V et al. | [Treatment for Legionnaires' disease. Macrolides or quinolones?]. | 2006 Jun-Jul | Enferm. Infecc. Microbiol. Clin. | pmid:16792936 |
Liu CL et al. | [Current infection of Mycoplasma pneumoniae in adults: clinical analysis of 13 hospitalized patients]. | 2006 | Zhonghua Yi Xue Za Zhi | pmid:16796860 |
Colakoglu S et al. | Prevalence and mechanisms of macrolide resistance in Streptococcus pyogenes in Ankara, Turkey. | 2006 | Scand. J. Infect. Dis. | pmid:16798693 |
Clement A et al. | Long term effects of azithromycin in patients with cystic fibrosis: A double blind, placebo controlled trial. | 2006 | Thorax | pmid:16809416 |
Chen BM et al. | Quantitative determination of azithromycin in human plasma by liquid chromatography-mass spectrometry and its application in a bioequivalence study. | 2006 | J Pharm Biomed Anal | pmid:16822633 |
Young LS et al. | Azithromycin for treatment of Mycobacterium avium-intracellulare complex infection in patients with AIDS. | 1991 | Lancet | pmid:1682544 |
Argani H et al. | Treatment of cyclosporine-induced gingival overgrowth with azithromycin-containing toothpaste. | 2006 | Exp Clin Transplant | pmid:16827637 |
Thoms KM et al. | [Two brothers with brown, reticulate hyperpigmentations. Papillomatosis confluens et reticularis (Gougerot-Carteaud): familial occurrence and response to azithromycin]. | 2006 | J Dtsch Dermatol Ges | pmid:16827916 |
Bradshaw CS et al. | Azithromycin failure in Mycoplasma genitalium urethritis. | 2006 | Emerging Infect. Dis. | pmid:16836839 |
Russo V et al. | Azithromycin-induced QT prolongation in elderly patient. | 2006 | Acta Biomed | pmid:16856707 |
Yasojima M et al. | Occurrence of levofloxacin, clarithromycin and azithromycin in wastewater treatment plant in Japan. | 2006 | Water Sci. Technol. | pmid:16862794 |
Edvinsson M et al. | Chlamydophila pneumoniae in chronic rhinosinusitis. | 2006 | Acta Otolaryngol. | pmid:16864493 |
Mousavi S et al. | Azithromycin in one week quadruple therapy for H pylori eradication in Iran. | 2006 | World J. Gastroenterol. | pmid:16874871 |
Merriam CV et al. | In vitro activity of azithromycin and nine comparator agents against 296 strains of oral anaerobes and 31 strains of Eikenella corrodens. | 2006 | Int. J. Antimicrob. Agents | pmid:16875802 |
Horner P | The case for further treatment studies of uncomplicated genital Chlamydia trachomatis infection. | 2006 | Sex Transm Infect | pmid:16877590 |
Huang W et al. | [Spectrophotometric determination of azithromycin by charge transfer reaction]. | 2006 | Guang Pu Xue Yu Guang Pu Fen Xi | pmid:16883867 |
Chaudhry SI et al. | A rash on the back. Diagnosis: confluent and reticulated papillomatosis (CRP) of Gougerot and Carteaud. | 2006 | Clin. Exp. Dermatol. | pmid:16901326 |
Cárceles CM et al. | Tissue disposition of azithromycin after intravenous and intramuscular administration to rabbits. | 2007 | Vet. J. | pmid:16904354 |
West SK et al. | Intensive insecticide spraying for fly control after mass antibiotic treatment for trachoma in a hyperendemic setting: a randomised trial. | 2006 | Lancet | pmid:16905024 |
Emerson PM et al. | The SAFE strategy for trachoma control: Using operational research for policy, planning and implementation. | 2006 | Bull. World Health Organ. | pmid:16917648 |
Vladusić I et al. | [Long term survival after Rhodococcus equi pneumonia in a patient with human immunodeficiency virus infection in the era of highly active antiretroviral therapy: case report and review]. | 2006 | Acta Med Croatica | pmid:16933840 |
Bergman M et al. | Macrolide and azithromycin use are linked to increased macrolide resistance in Streptococcus pneumoniae. | 2006 | Antimicrob. Agents Chemother. | pmid:16940064 |
Dolgushin II et al. | [Immunological and microbiological aspects of low intensity laser effect on the factors of local immunity of the reproductive tract in women with chlamydia infection]. | 2006 Jul-Aug | Zh. Mikrobiol. Epidemiol. Immunobiol. | pmid:16941885 |
Rackstraw S et al. | Can chlamydial conjunctivitis result from direct ejaculation into the eye? | 2006 | Int J STD AIDS | pmid:16942659 |
Furuya R et al. | In vitro synergistic effects of double combinations of beta-lactams and azithromycin against clinical isolates of Neisseria gonorrhoeae. | 2006 | J. Infect. Chemother. | pmid:16944253 |
Onodera S et al. | Enhancement of antimicrobial activities of cefteram or clavulanic acid/amoxicillin against cefixime-resistant Neisseria gonorrhoeae in the presence of clarithromycin or azithromycin. | 2006 | J. Infect. Chemother. | pmid:16944260 |
Tungikar SL et al. | Primary amebic meningoencephalitis. | 2006 | J Assoc Physicians India | pmid:16944619 |
Hand WL et al. | Increased polymorphonuclear leukocyte respiratory burst function in type 2 diabetes. | 2007 | Diabetes Res. Clin. Pract. | pmid:16959366 |
Daoud S and Boushi L | Azithromycin, ineffective in the treatment of old-world cutaneous leishmaniasis. | 2006 | Int. J. Dermatol. | pmid:16961538 |
Dean NC et al. | Improved clinical outcomes with utilization of a community-acquired pneumonia guideline. | 2006 | Chest | pmid:16963677 |
Rafiei R and Yaghoobi R | Azithromycin versus tetracycline in the treatment of acne vulgaris. | 2006 | J Dermatolog Treat | pmid:16971315 |
Atasoy M and AliaÄŸaoÄŸlu C | Is confluent and reticulated papillomatosis without papillomatosis early or late stage of confluent and reticulated papillomatosis? | 2006 | J. Cutan. Pathol. | pmid:16972956 |
Low N | Chlamydia (uncomplicated, genital). | 2006 | Clin Evid | pmid:16973080 |
Wagner BK et al. | Complications of a cat bite. | 2006 Sep-Oct | J Am Podiatr Med Assoc | pmid:16988179 |
Paul SR et al. | Polymorphous hemangioendothelioma in a child with acquired immunodeficiency syndrome (AIDS). | 2008 | Pediatr Blood Cancer | pmid:16991137 |
Atik B et al. | Impact of annual targeted treatment on infectious trachoma and susceptibility to reinfection. | 2006 | JAMA | pmid:17003397 |
Cochereau I et al. | Efficacy and safety of short duration azithromycin eye drops versus azithromycin single oral dose for the treatment of trachoma in children: a randomised, controlled, double-masked clinical trial. | 2007 | Br J Ophthalmol | pmid:17005549 |
Caronzolo D et al. | Effect of PEX, a noncatalytic metalloproteinase fragment with integrin-binding activity, on experimental Chlamydophila pneumoniae infection. | 2006 | Antimicrob. Agents Chemother. | pmid:17005805 |
Fa N et al. | Effect of the antibiotic azithromycin on thermotropic behavior of DOPC or DPPC bilayers. | 2006 | Chem. Phys. Lipids | pmid:17007828 |
Bukvić Krajacić M et al. | Azithromycin-sulfonamide conjugates as inhibitors of resistant Streptococcus pyogenes strains. | 2007 | Eur J Med Chem | pmid:17011079 |
Blau H et al. | Moxifloxacin but not ciprofloxacin or azithromycin selectively inhibits IL-8, IL-6, ERK1/2, JNK, and NF-kappaB activation in a cystic fibrosis epithelial cell line. | 2007 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:17012372 |
Halling SM and Jensen AE | Intrinsic and selected resistance to antibiotics binding the ribosome: analyses of Brucella 23S rrn, L4, L22, EF-Tu1, EF-Tu2, efflux and phylogenetic implications. | 2006 | BMC Microbiol. | pmid:17014718 |
Weinstein O et al. | Bilateral acute anterior uveitis as a presenting symptom of Mycoplasma pneumoniae infection. | 2006 | Can. J. Ophthalmol. | pmid:17016530 |
Bonacorsi S et al. | Treatment failure of nosocomial pertussis infection in a very-low-birth-weight neonate. | 2006 | J. Clin. Microbiol. | pmid:17021121 |
De Vecchi E et al. | In vitro induction of resistance by tissue concentrations of azithromycin, clarithromycin, cefixime and amoxicillin/clavulanate in clinical isolates of Streptococcus pyogenes. | 2006 | J Chemother | pmid:17024793 |
Tonkić M et al. | Primary resistance and antibiotic minimum inhibitory concentrations for Helicobacter pylori strains, in Split, Croatia. | 2006 | J Chemother | pmid:17024803 |
Santino I et al. | In vitro susceptibility of isolates of Borrelia burgdorferi s.l. to antimicrobial agents. | 2006 Jul-Sep | Int J Immunopathol Pharmacol | pmid:17026839 |
El-Rabbat N et al. | A validated spectrofluorometric assay for the determination of certain macrolide antibiotics in pharmaceutical formulations and spiked biological fluids. | 2006 Sep-Oct | J AOAC Int | pmid:17042176 |
Kosowska-Shick K et al. | Activity of DX-619 compared to other agents against viridans group streptococci, Streptococcus bovis, and Cardiobacterium hominis. | 2006 | Antimicrob. Agents Chemother. | pmid:17043120 |
Cigana C et al. | Anti-inflammatory effects of azithromycin in cystic fibrosis airway epithelial cells. | 2006 | Biochem. Biophys. Res. Commun. | pmid:17045242 |
Venner M et al. | Evaluation of tulathromycin in the treatment of pulmonary abscesses in foals. | 2007 | Vet. J. | pmid:17045497 |