Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Baker WL and Couch KA | Azithromycin for the secondary prevention of coronary artery disease: a meta-analysis. | 2007 | Am J Health Syst Pharm | pmid:17420199 |
| Chahine C et al. | Ultrashort regimen of lansoprazole-amoxicillin-azithromycin for eradicating Helicobacter pylori. | 2001 | Am J Health Syst Pharm | pmid:11596697 |
| Lo SH et al. | Azithromycin-induced hearing loss. | 1999 | Am J Health Syst Pharm | pmid:10690220 |
| Goldstein RC et al. | Fluoroquinolone- and ceftriaxone-based therapy of community-acquired pneumonia in hospitalized patients: the risk of subsequent isolation of multidrug-resistant organisms. | 2014 | Am J Infect Control | pmid:24773792 |
| Sorvillo F et al. | Incidence and determinants of Pseudomonas aeruginosa infection among persons with HIV: association with hospital exposure. | 2001 | Am J Infect Control | pmid:11287873 |
| Lilley LL and Guanci R | Distraction delays a dose. | 1998 | Am J Nurs | pmid:9473978 |
| Hashisaki GT | Update on macrolide antibiotics. | 1995 May-Jun | Am J Otolaryngol | pmid:7661309 |
| Marple BF et al. | Azithromycin extended release vs amoxicillin/clavulanate: symptom resolution in acute sinusitis. | 2010 Jan-Feb | Am J Otolaryngol | pmid:19944891 |
| El Hennawi DED et al. | Management of recurrent tonsillitis in children. | Am J Otolaryngol | pmid:28385329 | |
| Klapan I et al. | Azithromycin versus amoxicillin/clavulanate in the treatment of acute sinusitis. | 1999 Jan-Feb | Am J Otolaryngol | pmid:9950107 |
| Mvundura E et al. | Good pregnancy outcome with emergent cerclage placed in the presence of intra-amniotic microbial invasion. | 2007 | Am J Perinatol | pmid:17597442 |
| Crum NF et al. | Halting a pneumococcal pneumonia outbreak among United States Marine Corps trainees. | 2003 | Am J Prev Med | pmid:12880877 |
| Wolter JM et al. | Macrolides in cystic fibrosis: is there a role? | 2002 | Am J Respir Med | pmid:14720043 |
| Margaritis VK et al. | Sinus fluid penetration of oral clarithromycin and azithromycin in patients with acute rhinosinusitis. | 2007 Sep-Oct | Am J Rhinol | pmid:17999793 |
| Maniakas A and Desrosiers M | Azithromycin add-on therapy in high-risk postendoscopic sinus surgery patients failing corticosteroid irrigations: A clinical practice audit. | Am J Rhinol Allergy | pmid:24598145 | |
| Amali A et al. | Long-term postoperative azithromycin in patients with chronic rhinosinusitis: A randomized clinical trial. | Am J Rhinol Allergy | pmid:26637580 | |
| Bin Abdulhak AA et al. | Azithromycin and Risk of Cardiovascular Death: A Meta-Analytic Review of Observational Studies. | Am J Ther | pmid:25748818 | |
| Sutera L et al. | Azithromycin in an older woman with diabetic gastroparesis. | 2008 Jan-Feb | Am J Ther | pmid:18223358 |
| Muhlestein JB | Animal models of chlamydia and atherosclerosis. | 1999 | Am. Heart J. | pmid:10539862 |
| Gupta S | Chlamydia pneumoniae, monocyte activation, and azithromycin in coronary heart disease. | 1999 | Am. Heart J. | pmid:10539869 |
| Dunne M | WIZARD and the design of trials for secondary prevention of atherosclerosis with antibiotics. | 1999 | Am. Heart J. | pmid:10539870 |
| Grayston JT | Design of future intervention studies for Chlamydia pneumoniae in atherosclerosis. | 1999 | Am. Heart J. | pmid:10539875 |
| Hillis GS et al. | Effects of a brief course of azithromycin on soluble cell adhesion molecules and markers of inflammation in survivors of an acute coronary syndrome: A double-blind, randomized, placebo-controlled study. | 2004 | Am. Heart J. | pmid:15215794 |
| Gabrielli M et al. | Azithromycin on soluble cell adhesion molecules and markers of inflammation in survivors of an acute coronary syndrome. | 2005 | Am. Heart J. | pmid:16084141 |
| Schneider CA et al. | In vivo uptake of azithromycin in human coronary plaques. | 2000 | Am. J. Cardiol. | pmid:11018204 |
| Kuvin JT et al. | Effect of short-term antibiotic treatment on Chlamydia pneumoniae and peripheral endothelial function. | 2003 | Am. J. Cardiol. | pmid:12633811 |
| Hyodo E et al. | Effect of azithromycin therapy on coronary circulation in patients with coronary artery disease. | 2004 | Am. J. Cardiol. | pmid:15566918 |
| Lin L et al. | A retrospective study on clinical features of and treatment methods for 77 severe cases of SARS. | 2003 | Am. J. Chin. Med. | pmid:14992536 |
| Choi AH et al. | Clinicocytopathologic correlation in an atypical presentation of lymphadenopathy with review of literature. | 2015 | Am. J. Clin. Pathol. | pmid:25873511 |
| Sadatsafavi M et al. | The Association Between Rate and Severity of Exacerbations in Chronic Obstructive Pulmonary Disease: An Application of a Joint Frailty-Logistic Model. | 2016 | Am. J. Epidemiol. | pmid:27737842 |
| Koukounari A et al. | Using a nonparametric multilevel latent Markov model to evaluate diagnostics for trachoma. | 2013 | Am. J. Epidemiol. | pmid:23548755 |
| Bertoni G et al. | Triple therapy with azithromycin, omeprazole, and amoxicillin is highly effective in the eradication of Helicobacter pylori: a controlled trial versus omeprazole plus amoxicillin. | 1996 | Am. J. Gastroenterol. | pmid:8607489 |
| Di Mario F et al. | Azithromycin for the cure of Helicobacter pylori infection. | 1996 | Am. J. Gastroenterol. | pmid:8607490 |
| Tursi A et al. | The use of azithromycin in short-term low-dose triple therapies for Helicobacter pylori infection. | 1996 | Am. J. Gastroenterol. | pmid:8677967 |
| Sullivan B et al. | Comparison of azithromycin and clarithromycin in triple therapy regimens for the eradication of Helicobacter pylori. | 2002 | Am. J. Gastroenterol. | pmid:12385435 |
| Trevisani L et al. | A four-day low dose triple therapy regimen for the treatment of Helicobacter pylori infection. | 1998 | Am. J. Gastroenterol. | pmid:9517646 |
| al-Assi MT et al. | Azithromycin triple therapy for Helicobacter pylori infection: azithromycin, tetracycline, and bismuth. | 1995 | Am. J. Gastroenterol. | pmid:7872278 |
| Laine L et al. | Once-daily therapy for H. pylori infection: a randomized comparison of four regimens. | 1999 | Am. J. Gastroenterol. | pmid:10201465 |
| Mendu ML and Waikar SS | Drug-drug interactions and acute kidney injury: caveat prescriptor. | 2014 | Am. J. Kidney Dis. | pmid:24820318 |
| Hung AM and Hakim RM | Dialysate and serum potassium in hemodialysis. | 2015 | Am. J. Kidney Dis. | pmid:25828570 |
| Longo G et al. | Azithromycin-induced intrahepatic cholestasis. | 1997 | Am. J. Med. | pmid:9217574 |
| Hong BK et al. | "MAC" attack. | 2009 | Am. J. Med. | pmid:19958886 |
| Cameron DJ | Effectiveness of early Lyme disease treatment. | 1993 | Am. J. Med. | pmid:8388627 |
| Massarotti EM et al. | Treatment of early Lyme disease. | 1992 | Am. J. Med. | pmid:1313637 |
| Cascaval RI and Lancaster DJ | Hypersensitivity syndrome associated with azithromycin. | 2001 | Am. J. Med. | pmid:11247598 |
| Sheth A et al. | The traveling farm wife. | 2007 | Am. J. Med. | pmid:17208072 |
| Moellering RC | Introduction: revolutionary changes in the macrolide and azalide antibiotics. | 1991 | Am. J. Med. | pmid:1656735 |
| Neu HC | Clinical microbiology of azithromycin. | 1991 | Am. J. Med. | pmid:1656736 |
| Stamm WE | Azithromycin in the treatment of uncomplicated genital chlamydial infections. | 1991 | Am. J. Med. | pmid:1656737 |
| Hooton TM | A comparison of azithromycin and penicillin V for the treatment of streptococcal pharyngitis. | 1991 | Am. J. Med. | pmid:1656738 |
| Casiano RR | Azithromycin and amoxicillin in the treatment of acute maxillary sinusitis. | 1991 | Am. J. Med. | pmid:1656739 |
| Dark D | Multicenter evaluation of azithromycin and cefaclor in acute lower respiratory tract infections. | 1991 | Am. J. Med. | pmid:1656740 |
| Mallory SB | Azithromycin compared with cephalexin in the treatment of skin and skin structure infections. | 1991 | Am. J. Med. | pmid:1656741 |
| Hopkins S | Clinical toleration and safety of azithromycin. | 1991 | Am. J. Med. | pmid:1656742 |
| Schentag JJ and Ballow CH | Tissue-directed pharmacokinetics. | 1991 | Am. J. Med. | pmid:1656743 |
| Taylor SP et al. | Azithromycin for the Prevention of COPD Exacerbations: The Good, Bad, and Ugly. | 2015 | Am. J. Med. | pmid:26291905 |
| Baciewicz AM et al. | Azithromycin-induced hepatoxicity. | 2005 | Am. J. Med. | pmid:16378809 |
| Missov E and Cogswell R | Sudden cardiac death, mitral valve prolapse, and long QT syndrome. | 2015 | Am. J. Med. | pmid:26071830 |
| Winton JC and Twilla JD | Sudden cardiac arrest in a patient on chronic methadone after the addition of azithromycin. | 2013 | Am. J. Med. Sci. | pmid:23103438 |
| Devasia RA et al. | Compliance with azithromycin versus erythromycin in the setting of a pertussis outbreak. | 2009 | Am. J. Med. Sci. | pmid:19301451 |
| Sutton AL et al. | Perinatal pharmacokinetics of azithromycin for cesarean prophylaxis. | 2015 | Am. J. Obstet. Gynecol. | pmid:25595580 |
| Andrews WW et al. | Interconceptional antibiotics to prevent spontaneous preterm birth: a randomized clinical trial. | 2006 | Am. J. Obstet. Gynecol. | pmid:16522388 |
| Jacobson GF et al. | A randomized controlled trial comparing amoxicillin and azithromycin for the treatment of Chlamydia trachomatis in pregnancy. | 2001 | Am. J. Obstet. Gynecol. | pmid:11408852 |
| Tita AT et al. | Impact of interconception antibiotics on the endometrial microbial flora. | 2007 | Am. J. Obstet. Gynecol. | pmid:17346530 |
| Grigsby PL et al. | Maternal azithromycin therapy for Ureaplasma intraamniotic infection delays preterm delivery and reduces fetal lung injury in a primate model. | 2012 | Am. J. Obstet. Gynecol. | pmid:23111115 |
| Ward E and Duff P | A comparison of 3 antibiotic regimens for prevention of postcesarean endometritis: an historical cohort study. | 2016 | Am. J. Obstet. Gynecol. | pmid:26901276 |
| Gray RH et al. | Randomized trial of presumptive sexually transmitted disease therapy during pregnancy in Rakai, Uganda. | 2001 | Am. J. Obstet. Gynecol. | pmid:11717659 |
| Ramsey PS et al. | Maternal and transplacental pharmacokinetics of azithromycin. | 2003 | Am. J. Obstet. Gynecol. | pmid:12634646 |
| Lin KJ et al. | Safety of macrolides during pregnancy. | 2013 | Am. J. Obstet. Gynecol. | pmid:23254249 |
| Tita AT et al. | Impact of extended-spectrum antibiotic prophylaxis on incidence of postcesarean surgical wound infection. | 2008 | Am. J. Obstet. Gynecol. | pmid:18771992 |
| Johnson RB | The role of azalide antibiotics in the treatment of Chlamydia. | 1991 | Am. J. Obstet. Gynecol. | pmid:1645503 |
| Kelsey JJ et al. | Presence of azithromycin breast milk concentrations: a case report. | 1994 | Am. J. Obstet. Gynecol. | pmid:8178871 |
| Keelan JA et al. | Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep. | 2011 | Am. J. Obstet. Gynecol. | pmid:21481833 |
| Tita AT et al. | Clinical trial of interconceptional antibiotics to prevent preterm birth: subgroup analyses and possible adverse antibiotic-microbial interaction. | 2007 | Am. J. Obstet. Gynecol. | pmid:17904962 |
| Uy HS et al. | Infectious crystalline keratopathy and endophthalmitis secondary to Mycobacterium abscessus in a monocular patient with Stevens-Johnson syndrome. | 1999 | Am. J. Ophthalmol. | pmid:10030567 |
| Kuehne JJ et al. | Corneal pharmacokinetics of topically applied azithromycin and clarithromycin. | 2004 | Am. J. Ophthalmol. | pmid:15488779 |
| Bosch-Driessen LH et al. | A prospective, randomized trial of pyrimethamine and azithromycin vs pyrimethamine and sulfadiazine for the treatment of ocular toxoplasmosis. | 2002 | Am. J. Ophthalmol. | pmid:12095805 |
| Stewart WC et al. | Pharmacokinetics of azithromycin and moxifloxacin in human conjunctiva and aqueous humor during and after the approved dosing regimens. | 2010 | Am. J. Ophthalmol. | pmid:20813346 |
| Wolle MA et al. | Impact of Trichiasis surgery on physical functioning in Ethiopian patients: STAR trial. | 2011 | Am. J. Ophthalmol. | pmid:21333268 |
| Katusic D et al. | Azithromycin vs doxycycline in the treatment of inclusion conjunctivitis. | 2003 | Am. J. Ophthalmol. | pmid:12654359 |
| Abelson MB et al. | Clinical cure of bacterial conjunctivitis with azithromycin 1%: vehicle-controlled, double-masked clinical trial. | 2008 | Am. J. Ophthalmol. | pmid:18374301 |
| Ness PJ et al. | An anterior chamber toxicity study evaluating Besivance, AzaSite, and Ciprofloxacin. | 2010 | Am. J. Ophthalmol. | pmid:20678751 |
| Fan LC et al. | Macrolides protect against infection via inhibition of inflammasomes. | 2017 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:28684545 |
| Shinkai M et al. | Macrolide antibiotics modulate ERK phosphorylation and IL-8 and GM-CSF production by human bronchial epithelial cells. | 2006 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:16085674 |
| Blau H et al. | Moxifloxacin but not ciprofloxacin or azithromycin selectively inhibits IL-8, IL-6, ERK1/2, JNK, and NF-kappaB activation in a cystic fibrosis epithelial cell line. | 2007 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:17012372 |
| Tarran R et al. | Nonantibiotic macrolides prevent human neutrophil elastase-induced mucus stasis and airway surface liquid volume depletion. | 2013 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:23542952 |
| Kadova Z et al. | IL-1 receptor blockade alleviates endotoxin-mediated impairment of renal drug excretory functions in rats. | 2015 | Am. J. Physiol. Renal Physiol. | pmid:25503728 |
| Meyer M et al. | Azithromycin reduces exaggerated cytokine production by M1 alveolar macrophages in cystic fibrosis. | 2009 | Am. J. Respir. Cell Mol. Biol. | pmid:19244203 |
| Halldorsson S et al. | Azithromycin maintains airway epithelial integrity during Pseudomonas aeruginosa infection. | 2010 | Am. J. Respir. Cell Mol. Biol. | pmid:19372247 |
| Bergamini G et al. | Effects of azithromycin on glutathione S-transferases in cystic fibrosis airway cells. | 2009 | Am. J. Respir. Cell Mol. Biol. | pmid:19097986 |
| Stout JE and Floto RA | Treatment of Mycobacterium abscessus: all macrolides are equal, but perhaps some are more equal than others. | 2012 | Am. J. Respir. Crit. Care Med. | pmid:23118083 |
| Hayes D et al. | ABCA3 transporter deficiency. | 2012 | Am. J. Respir. Crit. Care Med. | pmid:23071193 |
| Williams TJ and Verleden GM | Azithromycin: a plea for multicenter randomized studies in lung transplantation. | 2005 | Am. J. Respir. Crit. Care Med. | pmid:16148194 |
| Saiman L et al. | Heterogeneity of treatment response to azithromycin in patients with cystic fibrosis. | 2005 | Am. J. Respir. Crit. Care Med. | pmid:16040785 |
| Kunisaki KM et al. | Vitamin D levels and risk of acute exacerbations of chronic obstructive pulmonary disease: a prospective cohort study. | 2012 | Am. J. Respir. Crit. Care Med. | pmid:22077070 |
| Yates B et al. | Azithromycin reverses airflow obstruction in established bronchiolitis obliterans syndrome. | 2005 | Am. J. Respir. Crit. Care Med. | pmid:15976371 |
| Hodge S et al. | Azithromycin improves macrophage phagocytic function and expression of mannose receptor in chronic obstructive pulmonary disease. | 2008 | Am. J. Respir. Crit. Care Med. | pmid:18420960 |
| Gerhardt SG et al. | Maintenance azithromycin therapy for bronchiolitis obliterans syndrome: results of a pilot study. | 2003 | Am. J. Respir. Crit. Care Med. | pmid:12672648 |
| O'Beirne SL et al. | Severe Cavitary, Fistulating Mycobacterium avium-intracellulare Complex Disease in an Immunocompetent Host. | 2015 | Am. J. Respir. Crit. Care Med. | pmid:26244303 |
| Albert RK and Schuller JL | Macrolide antibiotics and the risk of cardiac arrhythmias. | 2014 | Am. J. Respir. Crit. Care Med. | pmid:24707986 |