Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Kwun WH et al. | Effect of azithromycin in the treartment of cyclosporine-induced gingival hyperplasia in renal transplant recipients. | 2003 | Transplant. Proc. | pmid:12591416 |
Nafar M et al. | A comparison between the efficacy of systemic and local azithromycin therapy in treatment of cyclosporine induced gingival overgrowth in kidney transplant patients. | 2003 | Transplant. Proc. | pmid:14612094 |
Boran M et al. | Improvement in cyclosporine A associated gingival hyperplasia with azithromycin therapy. | 1996 | Transplant. Proc. | pmid:8769234 |
Verleden GM et al. | Efficacy of total lymphoid irradiation in azithromycin nonresponsive chronic allograft rejection after lung transplantation. | 2009 | Transplant. Proc. | pmid:19545735 |
Shullo MA et al. | Elevated tacrolimus levels associated with intravenous azithromycin and ceftriaxone: a case report. | 2010 | Transplant. Proc. | pmid:20620540 |
Nash MM and Zaltzman JS | Efficacy of azithromycin in the treatment of cyclosporine-induced gingival hyperplasia in renal transplant recipients. | 1998 | Transplantation | pmid:9665078 |
Verleden GM and Dupont LJ | Azithromycin therapy for patients with bronchiolitis obliterans syndrome after lung transplantation. | 2004 | Transplantation | pmid:15167610 |
Imai N et al. | A case of Campylobacter enteritis in a renal transplant recipient. | 2013 | Transplantation | pmid:23774778 |
Vos R et al. | Anti-inflammatory and immunomodulatory properties of azithromycin involved in treatment and prevention of chronic lung allograft rejection. | 2012 | Transplantation | pmid:22461039 |
Gottlieb J et al. | Long-term azithromycin for bronchiolitis obliterans syndrome after lung transplantation. | 2008 | Transplantation | pmid:18192909 |
Verleden SE et al. | Bronchiolitis obliterans syndrome and restrictive allograft syndrome: do risk factors differ? | 2013 | Transplantation | pmid:23425818 |
Wirnsberger GH and Pfragner R | Comment on "Efficacy of azithromycin in the treatment of cyclosporine-induced gingival hyperplasia in renal transplant recipients" by Nash and Zaltzman. | 1999 | Transplantation | pmid:10342326 |
Requena-Méndez A et al. | Enteric fever in Barcelona: Changing patterns of importation and antibiotic resistance. | Travel Med Infect Dis | pmid:27890811 | |
Dave J et al. | Trends in antibiotic susceptibility of enteric fever isolates in East London. | Travel Med Infect Dis | pmid:25964222 | |
Baneke A | Review: Targeting trachoma: Strategies to reduce the leading infectious cause of blindness. | 2012 | Travel Med Infect Dis | pmid:22326056 |
Swanson RN et al. | Once-daily azithromycin for 3 days compared with clarithromycin for 10 days for acute exacerbation of chronic bronchitis: a multicenter, double-blind, randomized study. | 2005 | Treat Respir Med | pmid:15725048 |
Cymbala AA et al. | The disease-modifying effects of twice-weekly oral azithromycin in patients with bronchiectasis. | 2005 | Treat Respir Med | pmid:15813663 |
Zervos M et al. | Comparative efficacies and tolerabilities of intravenous azithromycin plus ceftriaxone and intravenous levofloxacin with step-down oral therapy for hospitalized patients with moderate to severe community-acquired pneumonia. | 2004 | Treat Respir Med | pmid:15606222 |
What's in the water? | 1995 Mar-Apr | Treat Rev | pmid:11362299 | |
Azithro once a week for MAC. | 1998 | TreatmentUpdate | pmid:11365625 |