Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Dysentery, Bacillary D004405 6 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Anaplasmataceae Infections D000711 3 associated lipids
Pouchitis D019449 3 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Cryptosporidiosis D003457 3 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Neglected Diseases D058069 3 associated lipids
Giardiasis D005873 3 associated lipids
Chronic Disease D002908 7 associated lipids
Tick Infestations D013984 4 associated lipids
Retinitis D012173 4 associated lipids
Common Variable Immunodeficiency D017074 4 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Skin Diseases, Vesiculobullous D012872 5 associated lipids
Chlamydia Infections D002690 7 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Whooping Cough D014917 6 associated lipids
Urethritis D014526 9 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Yaws D015001 4 associated lipids
Syphilis, Latent D013592 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Vertigo D014717 4 associated lipids
Pelvic Pain D017699 7 associated lipids
Pneumonia, Pneumococcal D011018 3 associated lipids
Leishmaniasis, Cutaneous D016773 6 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Exanthema D005076 11 associated lipids
Lyme Disease D008193 5 associated lipids
Bronchiolitis D001988 6 associated lipids
Chlamydophila Infections D023521 4 associated lipids
Gingival Hyperplasia D005885 3 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Erythema Nodosum D004893 5 associated lipids
Pemphigus D010392 3 associated lipids
Trichomonas Infections D014245 3 associated lipids
Acinetobacter Infections D000151 4 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Failed Back Surgery Syndrome D055111 3 associated lipids
Uveitis, Intermediate D015867 3 associated lipids
Digestive System Diseases D004066 3 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Chancroid D002602 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Kwun WH et al. Effect of azithromycin in the treartment of cyclosporine-induced gingival hyperplasia in renal transplant recipients. 2003 Transplant. Proc. pmid:12591416
Nafar M et al. A comparison between the efficacy of systemic and local azithromycin therapy in treatment of cyclosporine induced gingival overgrowth in kidney transplant patients. 2003 Transplant. Proc. pmid:14612094
Boran M et al. Improvement in cyclosporine A associated gingival hyperplasia with azithromycin therapy. 1996 Transplant. Proc. pmid:8769234
Verleden GM et al. Efficacy of total lymphoid irradiation in azithromycin nonresponsive chronic allograft rejection after lung transplantation. 2009 Transplant. Proc. pmid:19545735
Shullo MA et al. Elevated tacrolimus levels associated with intravenous azithromycin and ceftriaxone: a case report. 2010 Transplant. Proc. pmid:20620540
Nash MM and Zaltzman JS Efficacy of azithromycin in the treatment of cyclosporine-induced gingival hyperplasia in renal transplant recipients. 1998 Transplantation pmid:9665078
Verleden GM and Dupont LJ Azithromycin therapy for patients with bronchiolitis obliterans syndrome after lung transplantation. 2004 Transplantation pmid:15167610
Imai N et al. A case of Campylobacter enteritis in a renal transplant recipient. 2013 Transplantation pmid:23774778
Vos R et al. Anti-inflammatory and immunomodulatory properties of azithromycin involved in treatment and prevention of chronic lung allograft rejection. 2012 Transplantation pmid:22461039
Gottlieb J et al. Long-term azithromycin for bronchiolitis obliterans syndrome after lung transplantation. 2008 Transplantation pmid:18192909
Verleden SE et al. Bronchiolitis obliterans syndrome and restrictive allograft syndrome: do risk factors differ? 2013 Transplantation pmid:23425818
Wirnsberger GH and Pfragner R Comment on "Efficacy of azithromycin in the treatment of cyclosporine-induced gingival hyperplasia in renal transplant recipients" by Nash and Zaltzman. 1999 Transplantation pmid:10342326
Requena-Méndez A et al. Enteric fever in Barcelona: Changing patterns of importation and antibiotic resistance. Travel Med Infect Dis pmid:27890811
Dave J et al. Trends in antibiotic susceptibility of enteric fever isolates in East London. Travel Med Infect Dis pmid:25964222
Baneke A Review: Targeting trachoma: Strategies to reduce the leading infectious cause of blindness. 2012 Travel Med Infect Dis pmid:22326056
Swanson RN et al. Once-daily azithromycin for 3 days compared with clarithromycin for 10 days for acute exacerbation of chronic bronchitis: a multicenter, double-blind, randomized study. 2005 Treat Respir Med pmid:15725048
Cymbala AA et al. The disease-modifying effects of twice-weekly oral azithromycin in patients with bronchiectasis. 2005 Treat Respir Med pmid:15813663
Zervos M et al. Comparative efficacies and tolerabilities of intravenous azithromycin plus ceftriaxone and intravenous levofloxacin with step-down oral therapy for hospitalized patients with moderate to severe community-acquired pneumonia. 2004 Treat Respir Med pmid:15606222
What's in the water? 1995 Mar-Apr Treat Rev pmid:11362299
Azithro once a week for MAC. 1998 TreatmentUpdate pmid:11365625