Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Mortensen JE et al. | In vitro activity of oral antimicrobial agents against clinical isolates of Pasteurella multocida. | 1998 | Diagn. Microbiol. Infect. Dis. | pmid:9554176 |
Dietz A et al. | [Macrolide antibiotic-induced vasculitis (Churg-Strauss syndrome)]. | 1998 | Laryngorhinootologie | pmid:9555706 |
Hoppe JE and Bryskier A | In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to two ketolides (HMR 3004 and HMR 3647), four macrolides (azithromycin, clarithromycin, erythromycin A, and roxithromycin), and two ansamycins (rifampin and rifapentine). | 1998 | Antimicrob. Agents Chemother. | pmid:9559823 |
Levert H et al. | Azithromycin impact on neutrophil oxidative metabolism depends on exposure time. | 1998 | Inflammation | pmid:9561928 |
Meguro H and Terashima I | [Clinical evaluation of a new macrolide antibiotic, azithromycin, in the pediatric field]. | 1997 | Jpn J Antibiot | pmid:9575355 |
Goldstein EJ et al. | Trovafloxacin compared with levofloxacin, ofloxacin, ciprofloxacin, azithromycin and clarithromycin against unusual aerobic and anaerobic human and animal bite-wound pathogens. | 1998 | J. Antimicrob. Chemother. | pmid:9578167 |
Varvara G and D'Arcangelo C | [The evaluation of the clinical efficacy and tolerance of azithromycin in odontostomatological infections]. | 1998 Jan-Feb | Minerva Stomatol | pmid:9578649 |
Miller SR et al. | Delayed cellulitis associated with conservative therapy for breast cancer. | 1998 | J Surg Oncol | pmid:9579371 |
Scaglione F and Rossoni G | Comparative anti-inflammatory effects of roxithromycin, azithromycin and clarithromycin. | 1998 | J. Antimicrob. Chemother. | pmid:9579712 |
Goldstein EJ et al. | Activities of HMR 3004 (RU 64004) and HMR 3647 (RU 66647) compared to those of erythromycin, azithromycin, clarithromycin, roxithromycin, and eight other antimicrobial agents against unusual aerobic and anaerobic human and animal bite pathogens isolated from skin and soft tissue infections in humans. | 1998 | Antimicrob. Agents Chemother. | pmid:9593139 |
Spangler SK et al. | Postantibiotic effect and postantibiotic sub-MIC effect of levofloxacin compared to those of ofloxacin, ciprofloxacin, erythromycin, azithromycin, and clarithromycin against 20 pneumococci. | 1998 | Antimicrob. Agents Chemother. | pmid:9593160 |
Matlow A et al. | Susceptibilities of neonatal respiratory isolates of Ureaplasma urealyticum to antimicrobial agents. | 1998 | Antimicrob. Agents Chemother. | pmid:9593171 |
Wang H et al. | [Polymerase chain reaction in the detection of patients infected by Chlamydia trachomatis after treatment]. | 1997 | Zhonghua Yi Xue Za Zhi | pmid:9596935 |
Yanami J et al. | [Tumor neovascularization inhibiting and tumor proliferation and metastasis suppressing actions of 14-, 15-, and 16-member ring macrolides]. | 1998 | Jpn J Antibiot | pmid:9597489 |
Inoue K et al. | [Inhibitory effects of macrolide antibiotics on infiltration and proliferation of lung cancer cell lines, A-549 and SBC-3]. | 1998 | Jpn J Antibiot | pmid:9597493 |
Nakayama I et al. | [Transport of azithromycin into infected tissue observed by macro- and microautoradiography]. | 1998 | Jpn J Antibiot | pmid:9597509 |
Dionisio D et al. | Chronic cryptosporidiosis in patients with AIDS: stable remission and possible eradication after long-term, low dose azithromycin. | 1998 | J. Clin. Pathol. | pmid:9602688 |
Clement PA and de Gandt JB | A comparison of the efficacy, tolerability and safety of azithromycin and co-amoxiclav in the treatment of sinusitis in adults. | 1998 Mar-Apr | J. Int. Med. Res. | pmid:9602984 |
Mitrokhin SD et al. | [Susceptibility of community-acquired pneumonia pathogens to azithromycin]. | 1998 | Antibiot. Khimioter. | pmid:9606504 |
Thornton AC et al. | Prevention of experimental Haemophilus ducreyi infection: a randomized, controlled clinical trial. | 1998 | J. Infect. Dis. | pmid:9607840 |