Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

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Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Dysentery, Bacillary D004405 6 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Anaplasmataceae Infections D000711 3 associated lipids
Pouchitis D019449 3 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Cryptosporidiosis D003457 3 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Neglected Diseases D058069 3 associated lipids
Giardiasis D005873 3 associated lipids
Chronic Disease D002908 7 associated lipids
Tick Infestations D013984 4 associated lipids
Retinitis D012173 4 associated lipids
Common Variable Immunodeficiency D017074 4 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Skin Diseases, Vesiculobullous D012872 5 associated lipids
Chlamydia Infections D002690 7 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Whooping Cough D014917 6 associated lipids
Urethritis D014526 9 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Yaws D015001 4 associated lipids
Syphilis, Latent D013592 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Vertigo D014717 4 associated lipids
Pelvic Pain D017699 7 associated lipids
Pneumonia, Pneumococcal D011018 3 associated lipids
Leishmaniasis, Cutaneous D016773 6 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Exanthema D005076 11 associated lipids
Lyme Disease D008193 5 associated lipids
Bronchiolitis D001988 6 associated lipids
Chlamydophila Infections D023521 4 associated lipids
Gingival Hyperplasia D005885 3 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Erythema Nodosum D004893 5 associated lipids
Pemphigus D010392 3 associated lipids
Trichomonas Infections D014245 3 associated lipids
Acinetobacter Infections D000151 4 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Failed Back Surgery Syndrome D055111 3 associated lipids
Uveitis, Intermediate D015867 3 associated lipids
Digestive System Diseases D004066 3 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Chancroid D002602 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Azmanis P et al. First detection of Cryptosporidium parvum in falcons (Falconiformes): Diagnosis, molecular sequencing, therapeutic trial and epidemiological assessment of a possible emerging disease in captive falcons. 2018 Vet. Parasitol. pmid:29559142
Hetzel U et al. Mycobacterium malmoense as an extrapulmonary pathogen of cats. 2012 Vet. Rec. pmid:22865116
Venner M et al. Comparison of tulathromycin, azithromycin and azithromycin-rifampin for the treatment of mild pneumonia associated with Rhodococcus equi. 2013 Vet. Rec. pmid:24106244
Moshkani SK and Dalimi A Evaluation of the efficacy of atovaquone alone or in combination with azithromycin against acute murine toxoplasmosis. 2000 Vet. Res. Commun. pmid:10836275
Guo Y et al. Chlamydiaphage φCPG1 Capsid Protein Vp1 Inhibits Chlamydia trachomatis Growth via the Mitogen-Activated Protein Kinase Pathway. 2016 Viruses pmid:27089359
Garasiuta EG [Surgical treatment of ulnar and pre-patellar bursitis under ambulatory conditions]. 2000 Voen Med Zh pmid:12886538
Klochkov OI et al. [The use of azithromycin in prophylaxis of respiratory infections occurred in the organized collectives, clinical sequelae]. 2004 Voen Med Zh pmid:15675752
Guchev IA et al. [Prophylaxis of pneumonia occurring outside the hospital in organized groups]. 2003 Voen Med Zh pmid:12722363
Guchev IA et al. [Effect of chemoprophylaxis on pneumonia incidence in organized groups]. 2003 Voen Med Zh pmid:12722514
Yazdanbakhsh AR et al. Reduction of non-Betalactam Antibiotics COD by Combined Coagulation and Advanced Oxidation Processes. 2016 Water Environ. Res. pmid:28661328
Walters E et al. Occurrence and loss over three years of 72 pharmaceuticals and personal care products from biosolids-soil mixtures in outdoor mesocosms. 2010 Water Res. pmid:20728197
Yasojima M et al. Occurrence of levofloxacin, clarithromycin and azithromycin in wastewater treatment plant in Japan. 2006 Water Sci. Technol. pmid:16862794
Odugbemi T et al. Single oral dose of azithromycin for therapy of susceptible sexually transmitted diseases: a multicenter open evaluation. 1993 Jul-Sep West Afr J Med pmid:8312208
Swanston WH et al. Single dose (direct observed) azithromycin therapy for Neisseria gonorrhoeae and Chlamydia trachomatis in STD clinic attenders with genital discharge in Trinidad and Tobago. 2001 West Indian Med J pmid:11769023
Kanatani MS and Guglielmo BJ The new macrolides. Azithromycin and clarithromycin. 1994 West. J. Med. pmid:8128699
Wenisch C [Pharmacokinetic effects of antibiotics on the development of bacterial resistance particularly in reference to azithromycin]. 2000 Wien Med Wochenschr pmid:10756595
Kratzer C et al. Comparative activities of antibiotics against intracellular non-typeable Haemophilus influenzae. 2007 Wien. Klin. Wochenschr. pmid:17571234
Hunfeld KP and Brade V Antimicrobial susceptibility of Borrelia burgdorferi sensu lato: what we know, what we don't know, and what we need to know. 2006 Wien. Klin. Wochenschr. pmid:17160604
Arnez M et al. Solitary erythema migrans in children: comparison of treatment with azithromycin and phenoxymethylpenicillin. 2002 Wien. Klin. Wochenschr. pmid:12422590
Maraspin V et al. Development of erythema migrans in spite of treatment with antibiotics after a tick bite. 2002 Wien. Klin. Wochenschr. pmid:12422612