Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Pieh C et al. | [Cotton wool spots in a 16-year-old girl]. | 2005 | Ophthalmologe | pmid:15095109 |
Guchev IA et al. | Two regimens of azithromycin prophylaxis against community-acquired respiratory and skin/soft-tissue infections among military trainees. | 2004 | Clin. Infect. Dis. | pmid:15095213 |
Fernandez-Obregon A | Oral use of azithromycin for the treatment of acne rosacea. | 2004 | Arch Dermatol | pmid:15096385 |
Kohlhoff SA et al. | In vitro activity of a novel diaminopyrimidine compound, iclaprim, against Chlamydia trachomatis and C. pneumoniae. | 2004 | Antimicrob. Agents Chemother. | pmid:15105151 |
Sakran W et al. | Susceptibility of Streptococcus pyogenes to two macrolides in northern Israel. | 2004 | Int. J. Antimicrob. Agents | pmid:15120735 |
Bakar O et al. | Therapeutic potential of azithromycin in rosacea. | 2004 | Int. J. Dermatol. | pmid:15125511 |
Worm HC et al. | High prevalence of Chlamydia pneumoniae infection in cyclosporin A-induced post-transplant gingival overgrowth tissue and evidence for the possibility of persistent infection despite short-term treatment with azithromycin. | 2004 | Nephrol. Dial. Transplant. | pmid:15128877 |
Gonzalez BE et al. | Azithromycin compared with beta-lactam antibiotic treatment failures in pneumococcal infections of children. | 2004 | Pediatr. Infect. Dis. J. | pmid:15131461 |
Gribajcević M et al. | [Clinical effectiveness of omeprazole, azithromycin and amoxicillin in ulcer healing and eradication of Helicobacter pylori infection]. | 2003 | Med Arh | pmid:15137249 |
Parry CM | The treatment of multidrug-resistant and nalidixic acid-resistant typhoid fever in Viet Nam. | 2004 | Trans. R. Soc. Trop. Med. Hyg. | pmid:15138078 |
Klass P | Index case. | 2004 | N. Engl. J. Med. | pmid:15141038 |
Duran D et al. | Theoretical study of selective methylation in the synthesis of azithromycin. | 2004 | J. Comput. Aided Mol. Des. | pmid:15143799 |
Wyrick PB and Knight ST | Pre-exposure of infected human endometrial epithelial cells to penicillin in vitro renders Chlamydia trachomatis refractory to azithromycin. | 2004 | J. Antimicrob. Chemother. | pmid:15163653 |
Agmon I et al. | Ribosomal crystallography: a flexible nucleotide anchoring tRNA translocation, facilitates peptide-bond formation, chirality discrimination and antibiotics synergism. | 2004 | FEBS Lett. | pmid:15165888 |
Verleden GM and Dupont LJ | Azithromycin therapy for patients with bronchiolitis obliterans syndrome after lung transplantation. | 2004 | Transplantation | pmid:15167610 |
Davies G and Wilson R | Prophylactic antibiotic treatment of bronchiectasis with azithromycin. | 2004 | Thorax | pmid:15170047 |
Kaul R et al. | Monthly antibiotic chemoprophylaxis and incidence of sexually transmitted infections and HIV-1 infection in Kenyan sex workers: a randomized controlled trial. | 2004 | JAMA | pmid:15173146 |
Peeling RW and Mabey DC | Syphilis. | 2004 | Nat. Rev. Microbiol. | pmid:15181902 |
Hammerschlag MR and Roblin PM | The in vitro activity of a new fluoroquinolone, ABT-492, against recent clinical isolates of Chlamydia pneumoniae. | 2004 | J. Antimicrob. Chemother. | pmid:15190026 |
Hunfeld KP et al. | New real-time PCR-based method for in vitro susceptibility testing of Anaplasma phagocytophilum against antimicrobial agents. | 2004 | Int. J. Antimicrob. Agents | pmid:15194126 |
le Normand Y et al. | [Software modeling for better understanding of pharmacokinetic-pharmacodynamic relationships: application to azithromycin in the treatment of streptococcal tonsillitis and in acute exacerbation fo chronic bronchitis]]. | 2004 Jan-Feb | Therapie | pmid:15199685 |
Halpern MT and Cifaldi MA | Is azithromycin the first-choice macrolide for treatment of community-acquired pneumonia? | 2004 | Clin. Infect. Dis. | pmid:15206068 |
Carr RR and Nahata MC | Azithromycin for improving pulmonary function in cystic fibrosis. | 2004 | Ann Pharmacother | pmid:15213312 |
Michot JM et al. | Active efflux of ciprofloxacin from J774 macrophages through an MRP-like transporter. | 2004 | Antimicrob. Agents Chemother. | pmid:15215125 |
Hoberman A and Paradise JL | Study design questions in treatment of children with acute otitis media. | 2004 | Antimicrob. Agents Chemother. | pmid:15215151 |
Drago L et al. | Selection of resistance of telithromycin against Haemophilus influenzae, Moraxella catarrhalis and streptococci in comparison with macrolides. | 2004 | J. Antimicrob. Chemother. | pmid:15215227 |
Hillis GS et al. | Effects of a brief course of azithromycin on soluble cell adhesion molecules and markers of inflammation in survivors of an acute coronary syndrome: A double-blind, randomized, placebo-controlled study. | 2004 | Am. Heart J. | pmid:15215794 |
Wu Y et al. | Studies on electrochemical oxidation of azithromycin and its interaction with bovine serum albumin. | 2004 | Bioelectrochemistry | pmid:15219252 |
Hahn DL and Plane MB | Feasibility of a practical clinical trial for asthma conducted in primary care. | 2004 May-Jun | J Am Board Fam Pract | pmid:15226283 |
Langley JM et al. | Azithromycin is as effective as and better tolerated than erythromycin estolate for the treatment of pertussis. | 2004 | Pediatrics | pmid:15231980 |
Clyti E et al. | [Short treatment of donovanosis with azithromycin]. | 2004 | Ann Dermatol Venereol | pmid:15235534 |
Snider LA and Swedo SE | PANDAS: current status and directions for research. | 2004 | Mol. Psychiatry | pmid:15241433 |
Jacobs MR et al. | Study design questions in treatment of children with acute otitis media. | 2004 | Antimicrob. Agents Chemother. | pmid:15241848 |
Lukehart SA et al. | Macrolide resistance in Treponema pallidum in the United States and Ireland. | 2004 | N. Engl. J. Med. | pmid:15247355 |
Antibiotics ineffective for prevention of recurrent MI. | 2004 | J Fam Pract | pmid:15251088 | |
Mizunoe S et al. | Clarithromycin and azithromycin induce apoptosis of activated lymphocytes via down-regulation of Bcl-xL. | 2004 | Int. Immunopharmacol. | pmid:15251115 |
Bouwman JJ et al. | Azithromycin inhibits interleukin-6 but not fibrinogen production in hepatocytes infected with cytomegalovirus and chlamydia pneumoniae. | 2004 | J. Lab. Clin. Med. | pmid:15252403 |
Tindberg Y et al. | Helicobacter pylori eradication in children and adolescents by a once daily 6-day treatment with or without a proton pump inhibitor in a double-blind randomized trial. | 2004 | Aliment. Pharmacol. Ther. | pmid:15274666 |
Sicuranza GB and Figueroa R | Pregnancy in a woman with unilateral lung agenesis. | 2004 | J. Matern. Fetal. Neonatal. Med. | pmid:15280115 |
Scheinfeld NS et al. | Macrolides in dermatology. | 2004 | Dis Mon | pmid:15280867 |
Silva-Vergara ML et al. | Azithromycin in the treatment of mucosal leishmaniasis. | 2004 May-Jun | Rev. Inst. Med. Trop. Sao Paulo | pmid:15286825 |
Nariai A et al. | [Efficacy of azithromycin as the empiric therapy in children with community-acquired pneumonia who were isolated macrolide resistant Streptococcus pneumoniae from nasopharynx]. | 2004 | Kansenshogaku Zasshi | pmid:15287476 |
Koeth LM et al. | Streptococcus pneumoniae in vitro development of resistance to amoxicillin/clavulanic acid, cefaclor, levofloxacin and azithromycin. | 2004 | Int. J. Antimicrob. Agents | pmid:15288313 |
Rahav G et al. | Azithromycin versus comparative therapy for the treatment of community acquired pneumonia. | 2004 | Int. J. Antimicrob. Agents | pmid:15288319 |
Skerk V et al. | Comparative randomized pilot study of azithromycin and doxycycline efficacy in the treatment of prostate infection caused by Chlamydia trachomatis. | 2004 | Int. J. Antimicrob. Agents | pmid:15288321 |
Lever MS et al. | In vitro susceptibility of Coxiella burnetii to azithromycin, doxycycline, ciprofloxacin and a range of newer fluoroquinolones. | 2004 | Int. J. Antimicrob. Agents | pmid:15288324 |
Gregory AR et al. | Ophthalmomyiasis caused by the sheep bot fly Oestrus ovis in northern Iraq. | 2004 | Optom Vis Sci | pmid:15300116 |
Nielsen HU et al. | Nasopharyngeal pathogens in children with acute otitis media in a low-antibiotic use country. | 2004 | Int. J. Pediatr. Otorhinolaryngol. | pmid:15302145 |
Shrader SP et al. | Azithromycin and warfarin interaction. | 2004 | Pharmacotherapy | pmid:15303459 |
Scheinfeld N | Telithromycin: a brief review of a new ketolide antibiotic. | 2004 Jul-Aug | J Drugs Dermatol | pmid:15303785 |
Melese M et al. | Feasibility of eliminating ocular Chlamydia trachomatis with repeat mass antibiotic treatments. | 2004 | JAMA | pmid:15304470 |
Zuckerman JM | Macrolides and ketolides: azithromycin, clarithromycin, telithromycin. | 2004 | Infect. Dis. Clin. North Am. | pmid:15308279 |
Kvien TK et al. | Three month treatment of reactive arthritis with azithromycin: a EULAR double blind, placebo controlled study. | 2004 | Ann. Rheum. Dis. | pmid:15308521 |
Addy LD and Martin MV | Azithromycin and dentistry - a useful agent? | 2004 | Br Dent J | pmid:15311248 |
Gryglicka B et al. | Evaluation of an anti-chlamydial antibiotic therapy influence on asthma patients. | 2003 | Ann Univ Mariae Curie Sklodowska Med | pmid:15315030 |
Marrie TJ | Experience with levofloxacin in a critical pathway for the treatment of community-acquired pneumonia. | 2004 | Chemotherapy | pmid:15319549 |
Birkenheuer AJ et al. | Efficacy of combined atovaquone and azithromycin for therapy of chronic Babesia gibsoni (Asian genotype) infections in dogs. | 2004 Jul-Aug | J. Vet. Intern. Med. | pmid:15320586 |
Giguère S et al. | Retrospective comparison of azithromycin, clarithromycin, and erythromycin for the treatment of foals with Rhodococcus equi pneumonia. | 2004 Jul-Aug | J. Vet. Intern. Med. | pmid:15320600 |
Ishimatsu Y et al. | Macrolide antibiotics induce apoptosis of human peripheral lymphocytes in vitro. | 2004 | Int. J. Antimicrob. Agents | pmid:15325428 |
Gattringer R et al. | Antimicrobial susceptibility and macrolide resistance genes in Streptococcus pyogenes collected in Austria and Hungary. | 2004 | Int. J. Antimicrob. Agents | pmid:15325435 |
Berquand A et al. | Real-time imaging of drug-membrane interactions by atomic force microscopy. | 2004 | Biochim. Biophys. Acta | pmid:15328052 |
Imamura Y et al. | Azithromycin inhibits MUC5AC production induced by the Pseudomonas aeruginosa autoinducer N-(3-Oxododecanoyl) homoserine lactone in NCI-H292 Cells. | 2004 | Antimicrob. Agents Chemother. | pmid:15328111 |
Riska PF et al. | Genetic and culture-based approaches for detecting macrolide resistance in Chlamydia pneumoniae. | 2004 | Antimicrob. Agents Chemother. | pmid:15328134 |
Bantar C et al. | An ex-vivo pharmacodynamic study comparing bactericidal activity of amoxicillin/sulbactam, azithromycin, doxycycline and levofloxacin against Streptococcus pneumoniae. | 2004 | J Chemother | pmid:15330320 |
Skerk V et al. | Azithromycin: 4.5- or 6.0-gram dose in the treatment of patients with chronic prostatitis caused by Chlamydia trachomatis--a randomized study. | 2004 | J Chemother | pmid:15332719 |
AltintaÅŸ E et al. | Comparison of ranitidine bismuth citrate, tetracycline and metronidazole with ranitidine bismuth citrate and azithromycin for the eradication of Helicobacter pylori in patients resistant to PPI based triple therapy. | 2004 | Turk J Gastroenterol | pmid:15334317 |
Yaqubi GH and Anani GR | Prevalence of trachoma in chronic conjunctivitis, Birjand, Islamic Republic of Iran. | 2002 Mar-May | East. Mediterr. Health J. | pmid:15339124 |
[Brief antibiotic therapy. 3 swallows in suppurative bronchitis]. | 2004 | MMW Fortschr Med | pmid:15347057 | |
Dunnebacke TH et al. | Balamuthia mandrillaris from soil samples. | 2004 | Microbiology (Reading, Engl.) | pmid:15347743 |
Komorsky-Lovrić S and Nigović B | Identification of 5-aminosalicylic acid, ciprofloxacin and azithromycin by abrasive stripping voltammetry. | 2004 | J Pharm Biomed Anal | pmid:15351051 |
Erdeve O et al. | The probiotic effect of Saccharomyces boulardii in a pediatric age group. | 2004 | J. Trop. Pediatr. | pmid:15357564 |
Tsai WC et al. | Azithromycin blocks neutrophil recruitment in Pseudomonas endobronchial infection. | 2004 | Am. J. Respir. Crit. Care Med. | pmid:15361366 |
Neerja J and Puri SK | Plasmodium yoelii: activity of azithromycin in combination with pyrimethamine or sulfadoxine against blood and sporozoite induced infections in Swiss mice. | 2004 Jul-Aug | Exp. Parasitol. | pmid:15363937 |
Ioannidis J and Wilkinson D | HIV: opportunistic infections. | 2003 | Clin Evid | pmid:15366175 |
McHugh RC et al. | A topical azithromycin preparation for the treatment of acne vulgaris and rosacea. | 2004 | J Dermatolog Treat | pmid:15370397 |
Cafini F et al. | Bactericidal activity of moxifloxacin against multidrug-resistant Streptoccocus pneumoniae at clinically achievable serum and epithelial lining fluid concentrations compared with three other antimicrobials. | 2004 | Int. J. Antimicrob. Agents | pmid:15380257 |
Quach C et al. | Effectiveness of amoxicillin, azithromycin, cefprozil and clarithromycin in the treatment of acute otitis media in children: a population-based study. | 2005 | Pharmacoepidemiol Drug Saf | pmid:15386697 |
Hoffmann T and Brunner H | Model for simulation of HIV/AIDS and cost-effectiveness of preventing non-tuberculous mycobacterial (MAC)-disease. | 2004 | Eur J Health Econ | pmid:15452749 |
Pirzada OM et al. | Improved lung function and body mass index associated with long-term use of Macrolide antibiotics. | 2003 | J. Cyst. Fibros. | pmid:15463852 |
Brian SR and Kimbrough RC | Salvage of a prosthetic knee joint infected with resistant pneumococcus. A case report. | 2004 | J Bone Joint Surg Am | pmid:15466745 |
Smelov V et al. | In vitro activity of fluoroquinolones, azithromycin and doxycycline against chlamydia trachomatis cultured from men with chronic lower urinary tract symptoms. | 2004 | Eur. Urol. | pmid:15474277 |
Pokrovskaia EV | [Final confirmation of inefficiency of antibiotics in secondary prevention of coronary heart disease. Results of PROVE IT (gatifloxacin trial) and ACES]. | 2004 | Kardiologiia | pmid:15477798 |
Mimesh S and Pratt M | Occupational airborne allergic contact dermatitis from azithromycin. | 2004 | Contact Derm. | pmid:15479208 |
Kapadia N and Talib A | Acne treated successfully with azithromycin. | 2004 | Int. J. Dermatol. | pmid:15485538 |
Kuehne JJ et al. | Corneal pharmacokinetics of topically applied azithromycin and clarithromycin. | 2004 | Am. J. Ophthalmol. | pmid:15488779 |
Atasoy M et al. | Treatment of confluent and reticulated papillomatosis with azithromycin. | 2004 | J. Dermatol. | pmid:15492444 |
Chidambaram JD et al. | Mass antibiotic treatment and community protection in trachoma control programs. | 2004 | Clin. Infect. Dis. | pmid:15494901 |
Kim YS et al. | A comparative trial of a single dose of azithromycin versus doxycycline for the treatment of mild scrub typhus. | 2004 | Clin. Infect. Dis. | pmid:15494910 |
Panpanich R et al. | Azithromycin for acute lower respiratory tract infections. | 2004 | Cochrane Database Syst Rev | pmid:15497172 |
Koytchev R et al. | Assessment of the bioequivalence of different formulations containing azithromycin (tablets and suspension). | 2004 | Arzneimittelforschung | pmid:15497663 |
Katz E et al. | Safety and efficacy of sequential i.v. to p.o. moxifloxacin versus conventional combination therapies for the treatment of community-acquired pneumonia in patients requiring initial i.v. therapy. | 2004 | J Emerg Med | pmid:15498622 |
Fernandez AD et al. | Azithromycin modulates murine immune responses to pneumococcal conjugate vaccine and inhibits nasal clearance of bacteria. | 2004 | J. Infect. Dis. | pmid:15499531 |
Matic V et al. | Antipneumococcal activities of two novel macrolides, GW 773546 and GW 708408, compared with those of erythromycin, azithromycin, clarithromycin, clindamycin, and telithromycin. | 2004 | Antimicrob. Agents Chemother. | pmid:15504828 |
Kosowska K et al. | Activities of two novel macrolides, GW 773546 and GW 708408, compared with those of telithromycin, erythromycin, azithromycin, and clarithromycin against Haemophilus influenzae. | 2004 | Antimicrob. Agents Chemother. | pmid:15504829 |
Saiman L | The use of macrolide antibiotics in patients with cystic fibrosis. | 2004 | Curr Opin Pulm Med | pmid:15510060 |
Southern KW and Barker PM | Azithromycin for cystic fibrosis. | 2004 | Eur. Respir. J. | pmid:15516680 |
Faber M et al. | [Evaluation of clinical effectiveness and direct costs of azithromycin treatment for exacerbation of chronic obstructive pulmonary disease in hospitalized patients and ambulatory care]. | 2004 | Pol. Merkur. Lekarski | pmid:15524029 |
Solomon AW et al. | Mass treatment with single-dose azithromycin for trachoma. | 2004 | N. Engl. J. Med. | pmid:15525721 |
Mariotti SP | New steps toward eliminating blinding trachoma. | 2004 | N. Engl. J. Med. | pmid:15525727 |
Gologan R et al. | Multiple myeloma in remission complicated by bone marrow granulomas. | 2003 | Rom J Intern Med | pmid:15526516 |