Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Trembizki E et al. | High levels of macrolide-resistant Mycoplasma genitalium in Queensland, Australia. | 2017 | J. Med. Microbiol. | pmid:28893363 |
Horner PJ and Martin DH | Mycoplasma genitalium Infection in Men. | 2017 | J. Infect. Dis. | pmid:28838074 |
Bradshaw CS et al. | New Horizons in Mycoplasma genitalium Treatment. | 2017 | J. Infect. Dis. | pmid:28838073 |
Gaydos CA | Mycoplasma genitalium: Accurate Diagnosis Is Necessary for Adequate Treatment. | 2017 | J. Infect. Dis. | pmid:28838072 |
Ribeiro M et al. | Azithromycin treatment is able to control the infection by two genotypes of Toxoplasma gondii in human trophoblast BeWo cells. | 2017 | Exp. Parasitol. | pmid:28803905 |
Benn K et al. | Bradycardia and Hypothermia Complicating Azithromycin Treatment. | 2017 | Am J Case Rep | pmid:28798290 |
Dolezelova E et al. | Resveratrol modifies biliary secretion of cholephilic compounds in sham-operated and cholestatic rats. | 2017 | World J. Gastroenterol. | pmid:29209109 |
Wang CM et al. | Synthesis and Antibacterial Evaluation of a Series of 11,12-Cyclic Carbonate Azithromycin-3-O-descladinosyl-3-O-carbamoyl Glycosyl Derivatives. | 2017 | Molecules | pmid:29207567 |
Rasmussen LD et al. | Follicular bronchiolitis in an HIV-infected individual on combination antiretroviral therapy with low CD4+ cell count but sustained viral suppression. | 2017 | BMJ Case Rep | pmid:29191821 |
Allan RN et al. | Cephalosporin-NO-donor prodrug PYRRO-C3D shows β-lactam-mediated activity against Streptococcus pneumoniae biofilms. | 2017 | Nitric Oxide | pmid:28235635 |
Wiesenfeld HC | Screening for Chlamydia trachomatis Infections in Women. | 2017 | N. Engl. J. Med. | pmid:28225683 |
Shmarina G et al. | Steady-State Therapy with Azithromycin or Low-Dose Prednisolone in Paediatric Cystic Fibrosis Patients: Inflammatory Markers and Disease Progression. | 2017 | Int. Arch. Allergy Immunol. | pmid:28219060 |
Ramappa M et al. | Successful Medical Management of Presumptive Pythium insidiosum Keratitis. | 2017 | Cornea | pmid:28207431 |
González-Beiras C et al. | Yaws Osteoperiostitis Treated with Single-Dose Azithromycin. | 2017 | Am. J. Trop. Med. Hyg. | pmid:28193743 |
Ivanová L et al. | Estimation of amount of selected pharmaceuticals sorbed onto digested sludge from wastewater treatment plant Bratislava-Petržalka. | 2017 | Environ. Res. | pmid:28183039 |
Thakur SD et al. | Resistance to Ceftriaxone and Azithromycin in Neisseria gonorrhoeae Isolates From 7 Countries of South America and the Caribbean: 2010-2011. | 2017 | Sex Transm Dis | pmid:28178114 |
Ra SW et al. | Azithromycin and risk of COPD exacerbations in patients with and without Helicobacter pylori. | 2017 | Respir. Res. | pmid:28558695 |
Campanón-Toro MV et al. | Acute generalized exanthematous pustulosis (AGEP) induced by azithromycin. | 2017 | Contact Derm. | pmid:28497632 |
Shastay A | The Absence of a Drug-Disease Interaction Alert Leads to a Child's Death. | 2017 | Home Healthc Now | pmid:28471797 |
Lahra MM and Enriquez RP | Australian Gonococcal Surveillance Programme, 1 July to 30 September 2016
. | 2017 | Commun Dis Intell Q Rep | pmid:28385144 |
White AC | Treatment of Early Syphilis in HIV: What Do We Really Know? | 2017 | Clin. Infect. Dis. | pmid:28362951 |
Trifirò G et al. | Use of azithromycin and risk of ventricular arrhythmia. | 2017 | CMAJ | pmid:28420680 |
Papp JR et al. | Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA. | 2017 | Emerging Infect. Dis. | pmid:28418303 |
Liu Y et al. | Azithromycin ameliorates airway remodeling via inhibiting airway epithelium apoptosis. | 2017 | Life Sci. | pmid:27916734 |
Vandooren J et al. | Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study. | 2017 | PLoS ONE | pmid:28369077 |
Valdés SO et al. | Cardiac Arrest in Pediatric Patients Receiving Azithromycin. | 2017 | J. Pediatr. | pmid:27912925 |
Bojang E et al. | Short-term increase in prevalence of nasopharyngeal carriage of macrolide-resistant Staphylococcus aureus following mass drug administration with azithromycin for trachoma control. | 2017 | BMC Microbiol. | pmid:28351345 |
Kong FY et al. | Pharmacokinetics of a single 1g dose of azithromycin in rectal tissue in men. | 2017 | PLoS ONE | pmid:28350806 |
Bornstein M et al. | Factors Associated With Primary Care Physician Knowledge of the Recommended Regimen for Treating Gonorrhea. | 2017 | Sex Transm Dis | pmid:27898574 |
Checa R et al. | Efficacy, safety and tolerance of imidocarb dipropionate versus atovaquone or buparvaquone plus azithromycin used to treat sick dogs naturally infected with the Babesia microti-like piroplasm. | 2017 | Parasit Vectors | pmid:28292316 |
Ishiguro N et al. | Therapeutic efficacy of azithromycin, clarithromycin, minocycline and tosufloxacin against macrolide-resistant and macrolide-sensitive Mycoplasma pneumoniae pneumonia in pediatric patients. | 2017 | PLoS ONE | pmid:28288170 |
Babić I et al. | Therapeutic efficacy of azithromycin and acetylcysteine in chronic otitis media with effusion. | 2017 | Eur Arch Otorhinolaryngol | pmid:27873023 |
Murphy TK et al. | A Double-Blind Randomized Placebo-Controlled Pilot Study of Azithromycin in Youth with Acute-Onset Obsessive-Compulsive Disorder. | 2017 | J Child Adolesc Psychopharmacol | pmid:28358599 |
Eyre DW et al. | WGS to predict antibiotic MICs for Neisseria gonorrhoeae. | 2017 | J. Antimicrob. Chemother. | pmid:28333355 |
Shan LS et al. | Effects of methylprednisolone or immunoglobulin when added to standard treatment with intravenous azithromycin for refractory Mycoplasma pneumoniae pneumonia in children. | 2017 | World J Pediatr | pmid:28130749 |
Daimee UA et al. | A 77-year-old man with fever and night sweats. | 2017 | Eur. J. Intern. Med. | pmid:27765389 |
Rajesh AM and Popat KM | Taste masking of azithromycin by resin complex and sustained release through interpenetrating polymer network with functionalized biopolymers. | 2017 | Drug Dev Ind Pharm | pmid:27600608 |
Purssell A et al. | Azithromycin and Doxycycline Attenuation of Acanthamoeba Virulence in a Human Corneal Tissue Model. | 2017 | J. Infect. Dis. | pmid:27578848 |
Romero L et al. | Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults. | 2017 | Cochrane Database Syst Rev | pmid:29226307 |
Dror T et al. | Microbiota manipulation for weight change. | 2017 | Microb. Pathog. | pmid:26792677 |
Lusk MJ et al. | Cervicitis: a prospective observational study of empiric azithromycin treatment in women with cervicitis and non-specific cervicitis. | 2017 | Int J STD AIDS | pmid:26792283 |
Marks M and Mabey D | Single-dose azithromycin to treat latent yaws. | 2017 | Lancet Glob Health | pmid:29107622 |
Mitjà O et al. | Effectiveness of single-dose azithromycin to treat latent yaws: a longitudinal comparative cohort study. | 2017 | Lancet Glob Health | pmid:29107621 |
Terkelsen D et al. | Multidrug-resistant infection with ceftriaxone resistance and intermediate resistance to azithromycin, Denmark, 2017. | 2017 | Euro Surveill. | pmid:29067905 |
Halhal B et al. | Pertussis Outbreak Among Soldiers During Basic Training: The Need for Updated Protocols. | 2017 | Mil Med | pmid:28291499 |
Çelik Payçu DG and Büyükbaba Boral Ö | [Effects of azithromycin and Chlorella vulgaris treatment on certain cytokine values and NK cell activity in an acute murine toxoplasmosis model]. | 2017 | Mikrobiyol Bul | pmid:28283010 |
Garcia-Vidal C et al. | Levofloxacin versus azithromycin for treating legionella pneumonia: a propensity score analysis. | 2017 | Clin. Microbiol. Infect. | pmid:28267637 |
Salman S et al. | Optimal Antimalarial Dose Regimens for Sulfadoxine-Pyrimethamine with or without Azithromycin in Pregnancy Based on Population Pharmacokinetic Modeling. | 2017 | Antimicrob. Agents Chemother. | pmid:28242669 |
Mathew A et al. | Antimicrobial and Immunomodulatory Surface-Functionalized Electrospun Membranes for Bone Regeneration. | 2017 | Adv Healthc Mater | pmid:28240815 |
Teng F et al. | In vitro characterization of pH-sensitive azithromycin-loaded methoxy poly (ethylene glycol)-block-poly (aspartic acid-graft-imidazole) micelles. | 2017 | J Colloid Interface Sci | pmid:28209540 |