Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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ZaÄtseva EA et al. | [Comparative study of the antimicrobial activity of pefloxacin, ciprofloxacin, norfloxacin and azithromycin with respect to Strains of Yersinia pseudotuberculosis]. | 1996 | Antibiot. Khimioter. | pmid:8762820 |
Lode H et al. | Azithromycin--review of key chemical, pharmacokinetic and microbiological features. | 1996 | J. Antimicrob. Chemother. | pmid:8818841 |
Girard AE et al. | Correlation of increased azithromycin concentrations with phagocyte infiltration into sites of localized infection. | 1996 | J. Antimicrob. Chemother. | pmid:8818842 |
Hultén K et al. | New pharmacokinetic in vitro model for studies of antibiotic activity against intracellular microorganisms. | 1996 | Antimicrob. Agents Chemother. | pmid:9124830 |
Marchisio P et al. | Comparative study of once-weekly azithromycin and once-daily amoxicillin treatments in prevention of recurrent acute otitis media in children. | 1996 | Antimicrob. Agents Chemother. | pmid:9124831 |
Hunt Gerardo S et al. | Comparison of Etest to broth microdilution method for testing Streptococcus pneumoniae susceptibility to levofloxacin and three macrolides. | 1996 | Antimicrob. Agents Chemother. | pmid:8891154 |
Chang HR | The potential role of azithromycin in the treatment of prophylaxis of toxoplasmosis. | 1996 | Int J STD AIDS | pmid:8652722 |
Waugh MA | Azithromycin in gonorrhoea. | 1996 | Int J STD AIDS | pmid:8652723 |
Young LS | Treatment and prophylaxis of Mycobacterium avium complex. | 1996 | Int J STD AIDS | pmid:8652724 |
Olsen KM et al. | Intrapulmonary pharmacokinetics of azithromycin in healthy volunteers given five oral doses. | 1996 | Antimicrob. Agents Chemother. | pmid:8913469 |
Kuo CC et al. | In vitro activities of azithromycin, clarithromycin, and other antibiotics against Chlamydia pneumoniae. | 1996 | Antimicrob. Agents Chemother. | pmid:8913488 |
Aoyama T et al. | Efficacy of short-term treatment of pertussis with clarithromycin and azithromycin. | 1996 | J. Pediatr. | pmid:8917247 |
Roord JJ et al. | Prospective open randomized study comparing efficacies and safeties of a 3-day course of azithromycin and a 10-day course of erythromycin in children with community-acquired acute lower respiratory tract infections. | 1996 | Antimicrob. Agents Chemother. | pmid:9124837 |
Wenisch C et al. | Effect of single oral dose of azithromycin, clarithromycin, and roxithromycin on polymorphonuclear leukocyte function assessed ex vivo by flow cytometry. | 1996 | Antimicrob. Agents Chemother. | pmid:8878577 |
Yeates RA et al. | Interaction between midazolam and clarithromycin: comparison with azithromycin. | 1996 | Int J Clin Pharmacol Ther | pmid:8880291 |
Amsden GW | Erythromycin, clarithromycin, and azithromycin: are the differences real? | 1996 Jan-Feb | Clin Ther | pmid:8851453 |
Preac Mursic V et al. | Kill kinetics of Borrelia burgdorferi and bacterial findings in relation to the treatment of Lyme borreliosis. | 1996 Jan-Feb | Infection | pmid:8852456 |
Baradaran-Dilmaghani R and Stanek G | In vitro susceptibility of thirty Borrelia strains from various sources against eight antimicrobial chemotherapeutics. | 1996 Jan-Feb | Infection | pmid:8852472 |
Strle F et al. | Azithromycin and doxycycline for treatment of Borrelia culture-positive erythema migrans. | 1996 Jan-Feb | Infection | pmid:8852473 |
Fontán PA et al. | Haemophilus influenzae type b exoproducts induce chemotaxis and macrolide antibiotic release by human polymorphonuclear leukocytes. | 1996 Jan-Feb | Chemotherapy | pmid:8751269 |
Ehret JM et al. | A clinical isolate of Neisseria gonorrhoeae with in vitro resistance to erythromycin and decreased susceptibility to azithromycin. | 1996 Jul-Aug | Sex Transm Dis | pmid:8836018 |
Lane G | Increased hypoprothrombinemic effect of warfarin possibly induced by azithromycin. | 1996 Jul-Aug | Ann Pharmacother | pmid:8826581 |
Diculencu D et al. | [The postantibiotic effect of azithromycin on respiratory pathogens]. | 1996 Jul-Dec | Rev Med Chir Soc Med Nat Iasi | pmid:9455450 |
Carlin EM and Barton SE | Azithromycin as the first-line treatment of non-gonococcal urethritis (NGU): a study of follow-up rates, contact attendance and patients' treatment preference. | 1996 May-Jun | Int J STD AIDS | pmid:8799780 |
Shanks GD et al. | Azithromycin prophylaxis prevents epidemic dysentery. | 1996 May-Jun | Trans. R. Soc. Trop. Med. Hyg. | pmid:8758091 |
Adam D et al. | Re: A. Bauernfeind et al.: Comparative pharmacodynamics of clarithromycin and azithromycin against respiratory pathogens (Infection 23 [1995] 316-321) | 1996 May-Jun | Infection | pmid:8811372 |
Vranes J | Effect of subinhibitory concentrations of ceftazidime, ciprofloxacin, and azithromycin on the hemagglutination and adherence of uropathogenic Escherichia coli strains. | 1996 May-Jun | Chemotherapy | pmid:8983884 |
Ichimiya T et al. | The influence of azithromycin on the biofilm formation of Pseudomonas aeruginosa in vitro. | 1996 May-Jun | Chemotherapy | pmid:8983885 |
Galova K et al. | Multicenter randomized study of two once daily regimens in the initial management of community-acquired respiratory tract infections in 163 children: azithromycin versus ceftibuten. | 1996 May-Jun | Chemotherapy | pmid:8983893 |
Burke SM | Azithromycin: only once a day. | 1996 May-Jun | MCN Am J Matern Child Nurs | pmid:8857402 |
Ripa S et al. | A linear model for the pharmacokinetics of azithromycin in healthy volunteers. | 1996 Nov-Dec | Chemotherapy | pmid:8957574 |
D'Amico R | ICAAC update on opportunistic infections. | 1996 Nov-Dec | Posit Aware | pmid:11363974 |
Wendel TD | 1-day azithromycin was as effective as 7-day doxycycline for nongonococcal urethritis syndrome in men. | 1996 Nov-Dec | ACP J. Club | pmid:8912627 |
Peeling RW and Brunham RC | Chlamydiae as pathogens: new species and new issues. | 1996 Oct-Dec | Emerging Infect. Dis. | pmid:8969247 |
Biebuyck XA | Comparison of azithromycin and co-amoxiclav in the treatment of acute tracheobronchitis and acute infectious exacerbations of chronic bronchitis in adults. Azithromycin Study Group. | 1996 Sep-Oct | J. Int. Med. Res. | pmid:8895044 |
Luke DR and Foulds G | Toleration of intravenous azithromycin. | 1997 | Ann Pharmacother | pmid:9296232 |
Brettle RP | Mycobacterium avium intracellulare infection in patients with HIV or AIDS. | 1997 | J. Antimicrob. Chemother. | pmid:9301979 |
Nasta P and Chiodera S | Azithromycin for relapsing cerebral toxoplasmosis in AIDS. | 1997 | AIDS | pmid:9233470 |
Charoenwatanachokchai A et al. | Azithromycin in the treatment of chlamydial cervicitis and eradication of Ureaplasma urealyticum in female lower genital tract. | 1997 | J Med Assoc Thai | pmid:9240007 |
Kitamura K et al. | [Pharmacokinetic and clinical evaluation of azithromycin in the pediatric field]. | 1997 | Jpn J Antibiot | pmid:9100081 |
Fietta A et al. | Inhibition of intracellular growth of Staphylococcus aureus by exposure of infected human monocytes to clarithromycin and azithromycin. | 1997 | J Chemother | pmid:9106013 |
Ficnar B et al. | Azithromycin: 3-day versus 5-day course in the treatment of respiratory tract infections in children. Croatian Azithromycin Study Group. | 1997 | J Chemother | pmid:9106016 |
Young H et al. | Azithromycin and erythromycin resistant Neisseria gonorrhoeae following treatment with azithromycin. | 1997 | Int J STD AIDS | pmid:9175650 |
Hoppe JE and Tschirner T | Comparison of Etest and agar dilution for testing the activity of three macrolides against Bordetella parapertussis. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9218920 |
Klein JO | History of macrolide use in pediatrics. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109154 |
McCracken GH | Microbiologic activity of the newer macrolide antibiotics. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109155 |
Tarlow MJ | Macrolides in the management of streptococcal pharyngitis/tonsillitis. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109157 |
Scaramuzza A et al. | Case of the month: a girl with oedema and purpuric eruption. Diagnosis: acute haemorrhagic oedema of infancy. | 1997 | Eur. J. Pediatr. | pmid:9365076 |
Vcev A et al. | [Omeprazole and azithromycin with and without metronidazole in the eradication of Helicobacter pylori in duodenal ulcer disease]. | 1997 | Lijec Vjesn | pmid:9471481 |
Wang H et al. | [Polymerase chain reaction in the detection of patients infected by Chlamydia trachomatis after treatment]. | 1997 | Zhonghua Yi Xue Za Zhi | pmid:9596935 |