Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Sidhu H et al. | Risk assessment of biosolids-borne ciprofloxacin and azithromycin. | 2019 | Sci. Total Environ. | pmid:30463165 |
Sidhu H et al. | Plant toxicity and accumulation of biosolids-borne ciprofloxacin and azithromycin. | 2019 | Sci. Total Environ. | pmid:30340267 |
Sidhu H et al. | Retention-release of ciprofloxacin and azithromycin in biosolids and biosolids-amended soils. | 2019 | Sci. Total Environ. | pmid:30196217 |
Sidhu H et al. | Bioavailability of biosolids-borne ciprofloxacin and azithromycin to terrestrial organisms: Microbial toxicity and earthworm responses. | 2019 | Sci. Total Environ. | pmid:30195128 |
Speer EM et al. | Pentoxifylline, dexamethasone and azithromycin demonstrate distinct age-dependent and synergistic inhibition of TLR- and inflammasome-mediated cytokine production in human newborn and adult blood in vitro. | 2018 | PLoS ONE | pmid:29715306 |
Pu Y et al. | Azithromycin ameliorates OVA-induced airway remodeling in Balb/c mice via suppression of epithelial-to-mesenchymal transition. | 2018 | Int. Immunopharmacol. | pmid:29567590 |
Chen QF and Zhang YW | [Clinical effect of Saccharomyces boulardii powder combined with azithromycin sequential therapy in treatment of children with diarrhea secondary to Mycoplasma pneumoniae pneumonia]. | 2018 | Zhongguo Dang Dai Er Ke Za Zhi | pmid:29429459 |
Abdulai AA et al. | Community-based mass treatment with azithromycin for the elimination of yaws in Ghana-Results of a pilot study. | 2018 | PLoS Negl Trop Dis | pmid:29566044 |
Azmanis P et al. | First detection of Cryptosporidium parvum in falcons (Falconiformes): Diagnosis, molecular sequencing, therapeutic trial and epidemiological assessment of a possible emerging disease in captive falcons. | 2018 | Vet. Parasitol. | pmid:29559142 |
Luo H et al. | Clinical characteristics from co-infection with avian influenza A H7N9 and Mycoplasma pneumoniae: a case report. | 2018 | J Med Case Rep | pmid:29540219 |
Horner P et al. | Which azithromycin regimen should be used for treating ? A meta-analysis. | 2018 | Sex Transm Infect | pmid:28717050 |
Kawamura K et al. | Adjunctive therapy with azithromycin for moderate and severe acute respiratory distress syndrome: a retrospective, propensity score-matching analysis of prospectively collected data at a single center. | 2018 | Int. J. Antimicrob. Agents | pmid:29501821 |
Bandyopadhyay R et al. | Effectiveness of treatment regimens for Typhoid fever in the nalidixic acid-resistant S. typhi (NARST) era in South India. | 2018 | Trop Doct | pmid:29495943 |
Mulugeta A et al. | Coverage, social mobilization and challenges of mass Zithromax administration campaign in South and South East zones of Tigray, Northern Ethiopia: A cross sectional study. | 2018 | PLoS Negl Trop Dis | pmid:29481558 |
Atkin PA and Simms ML | Orofacial granulomatosis: an unsuccessful response to weekly azithromycin pulse therapy. | 2018 | Oral Surg Oral Med Oral Pathol Oral Radiol | pmid:29477603 |
Liu YH et al. | Antimicrobial susceptibilities and molecular typing of neisseria gonorrhoeae isolates at a medical centre in Taiwan, 2001-2013 with an emphasis on high rate of azithromycin resistance among the isolates. | 2018 | Int. J. Antimicrob. Agents | pmid:29477549 |
Mannelli VK et al. | . | 2018 | BMJ Case Rep | pmid:29472421 |
de Oliveira Alves A et al. | Young Boy With Roughening in the Inner Eyelids. | 2018 | Ann Emerg Med | pmid:29458812 |
Astale T et al. | Population-based coverage survey results following the mass drug administration of azithromycin for the treatment of trachoma in Amhara, Ethiopia. | 2018 | PLoS Negl Trop Dis | pmid:29451881 |
Pan H and Ba-Thein W | Diagnostic Accuracy of Global Pharma Health Fund Minilabâ„¢ in Assessing Pharmacopoeial Quality of Antimicrobials. | 2018 | Am. J. Trop. Med. Hyg. | pmid:29141717 |
Chatterjee S and Agrawal D | Azithromycin in the Management of Pythium insidiosum Keratitis. | 2018 | Cornea | pmid:29095755 |
Thakur SD et al. | High levels of susceptibility to new and older antibiotics in Neisseria gonorrhoeae isolates from Saskatchewan (2003-15): time to consider point-of-care or molecular testing for precision treatment? | 2018 | J. Antimicrob. Chemother. | pmid:29029217 |
Kelly C et al. | Macrolide antibiotics for bronchiectasis. | 2018 | Cochrane Database Syst Rev | pmid:29543980 |
Li B et al. | The efficacy of azithromycin and doxycycline treatment for rectal chlamydial infection: a retrospective cohort study in South Australia. | 2018 | Intern Med J | pmid:28967178 |
Bogdan M et al. | In vitro effect of subminimal inhibitory concentrations of antibiotics on the biofilm formation ability of Acinetobacter baumannii clinical isolates. | 2018 | J Chemother | pmid:28956494 |
Wang R et al. | IncA/C plasmids conferring high azithromycin resistance in vibrio cholerae. | 2018 | Int. J. Antimicrob. Agents | pmid:28919196 |
Weston EJ et al. | Adherence to CDC Recommendations for the Treatment of Uncomplicated Gonorrhea - STD Surveillance Network, United States, 2016. | 2018 | MMWR Morb. Mortal. Wkly. Rep. | pmid:29698384 |
Keenan JD et al. | Azithromycin to Reduce Childhood Mortality in Sub-Saharan Africa. | 2018 | N. Engl. J. Med. | pmid:29694816 |
Marks M et al. | Comparative efficacy of low-dose versus standard-dose azithromycin for patients with yaws: a randomised non-inferiority trial in Ghana and Papua New Guinea. | 2018 | Lancet Glob Health | pmid:29456191 |
Sardana K et al. | An observational study of the efficacy of azithromycin in erythema annulare centrifugum. | 2018 | Clin. Exp. Dermatol. | pmid:29297941 |
Tung NT et al. | Formulation and biopharmaceutical evaluation of bitter taste masking microparticles containing azithromycin loaded in dispersible tablets. | 2018 | Eur J Pharm Biopharm | pmid:28359878 |
Kamio K and Azuma A | Diffuse panbronchiolitis: A fine road from the discovery of a disease to the establishment of treatment. | 2018 | Respir Investig | pmid:30049592 |
Zikic A et al. | Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis. | 2018 | J Pediatric Infect Dis Soc | pmid:30007329 |
Ersoy B et al. | The anti-inflammatory effects of erythromycin, clarithromycin, azithromycin and roxithromycin on histamine-induced otitis media with effusion in guinea pigs. | 2018 | J Laryngol Otol | pmid:29888693 |
Li JG et al. | [Eperythrozoonosis complicated with hemophagocytic syndrome: report of four cases and review of literature]. | 2018 | Zhonghua Er Ke Za Zhi | pmid:29614573 |
Tada H et al. | The effects of Lactobacillus reuteri probiotics combined with azithromycin on peri-implantitis: A randomized placebo-controlled study. | 2018 | J Prosthodont Res | pmid:28756115 |
Fleming-Dutra KE et al. | Variations in Antibiotic and Azithromycin Prescribing for Children by Geography and Specialty-United States, 2013. | 2018 | Pediatr. Infect. Dis. J. | pmid:28746259 |
Balci O and Gulkilik G | Assessment of efficacy of topical azithromycin 1.5 per cent ophthalmic solution for the treatment of meibomian gland dysfunction. | 2018 | Clin Exp Optom | pmid:28677153 |
Hong D et al. | [Atopic keratoconjunctivitis: One allergy may mask another. A clinical observation with two types of hypersensitivity reactions: IgE-mediated and non-IgE-mediated]. | 2018 | J Fr Ophtalmol | pmid:29567021 |
Thapa A et al. | Typhoid fever with isolated left lateral rectus palsy. | 2018 | BMJ Case Rep | pmid:30181402 |
Grewal TK et al. | Therapeutic implications of nano-encapsulated rifabutin, azithromycin & ethambutol against experimental infection in mice. | 2018 | Indian J. Med. Res. | pmid:30168492 |
Montazeri M et al. | Activities of anti-Toxoplasma drugs and compounds against tissue cysts in the last three decades (1987 to 2017), a systematic review. | 2018 | Parasitol. Res. | pmid:30088074 |
Tilahun Z and Fenta TG | Coverage of azithromycin mass treatment for trachoma elimination in Northwestern Ethiopia: a community based cross-sectional study. | 2018 | BMC Ophthalmol | pmid:30081851 |
Lundin MS et al. | Lemierre's syndrome and 2016 American College of Physician guidelines for pharyngitis: no to empiric coverage for bacterial pharyngitis. While no role for routine Fusobacterium PCR, keep suspicion for this pathogen. | 2018 | BMJ Case Rep | pmid:30030249 |
Celma A et al. | Development of a Retention Time Interpolation scale (RTi) for liquid chromatography coupled to mass spectrometry in both positive and negative ionization modes. | 2018 | J Chromatogr A | pmid:30005941 |
Lederhandler MH et al. | Severe Oral Mucositis: A Rare Adverse Event of Pembrolizumab. | 2018 | J Drugs Dermatol | pmid:30005106 |
Valor C and Huber K | Atypical presentation of cat scratch disease: Parinaud's oculoglandular syndrome with facial nerve paresis. | 2018 | BMJ Case Rep | pmid:29982178 |
Lanz J and Lautenschlager S | [CME Dermatology 16/Answer: Fever, Pustules and Joint Pain as Vacation Mementoes]. | 2018 | Praxis (Bern 1994) | pmid:29921188 |
Kalua K et al. | One round of azithromycin MDA adequate to interrupt transmission in districts with prevalence of trachomatous inflammation-follicular of 5.0-9.9%: Evidence from Malawi. | 2018 | PLoS Negl Trop Dis | pmid:29897902 |
Smotrys M et al. | Babesiosis as a cause of false-positive HIV serology. | 2018 | BMJ Case Rep | pmid:29884713 |