Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Trembizki E et al. | High levels of macrolide-resistant Mycoplasma genitalium in Queensland, Australia. | 2017 | J. Med. Microbiol. | pmid:28893363 |
| Lu Y et al. | Antibiotics Promote Escherichia coli-Pseudomonas aeruginosa Conjugation through Inhibiting Quorum Sensing. | 2017 | Antimicrob. Agents Chemother. | pmid:28993333 |
| Horner PJ and Martin DH | Mycoplasma genitalium Infection in Men. | 2017 | J. Infect. Dis. | pmid:28838074 |
| Wiesenfeld HC | Screening for Chlamydia trachomatis Infections in Women. | 2017 | N. Engl. J. Med. | pmid:28225683 |
| Shmarina G et al. | Steady-State Therapy with Azithromycin or Low-Dose Prednisolone in Paediatric Cystic Fibrosis Patients: Inflammatory Markers and Disease Progression. | 2017 | Int. Arch. Allergy Immunol. | pmid:28219060 |
| Ito A et al. | A Case of Community-Acquired Pneumonia Due to Legionella pneumophila Serogroup 9 Wherein Initial Treatment with Single-Dose Oral Azithromycin Appeared Useful. | 2017 | Jpn. J. Infect. Dis. | pmid:28890505 |
| Saiz JC and MartÃn-Acebes MA | Reply to Iannetta et al., "Azithromycin Shows Anti-Zika Virus Activity in Human Glial Cells". | 2017 | Antimicrob. Agents Chemother. | pmid:28839084 |
| Trifirò G et al. | Use of azithromycin and risk of ventricular arrhythmia. | 2017 | CMAJ | pmid:28420680 |
| Amza A et al. | A Cluster-Randomized Trial to Assess the Efficacy of Targeting Trachoma Treatment to Children. | 2017 | Clin. Infect. Dis. | pmid:27956455 |
| Papp JR et al. | Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA. | 2017 | Emerging Infect. Dis. | pmid:28418303 |
| Liu Y et al. | Azithromycin ameliorates airway remodeling via inhibiting airway epithelium apoptosis. | 2017 | Life Sci. | pmid:27916734 |
| Murphy TK et al. | A Double-Blind Randomized Placebo-Controlled Pilot Study of Azithromycin in Youth with Acute-Onset Obsessive-Compulsive Disorder. | 2017 | J Child Adolesc Psychopharmacol | pmid:28358599 |
| Eyre DW et al. | WGS to predict antibiotic MICs for Neisseria gonorrhoeae. | 2017 | J. Antimicrob. Chemother. | pmid:28333355 |
| Purssell A et al. | Azithromycin and Doxycycline Attenuation of Acanthamoeba Virulence in a Human Corneal Tissue Model. | 2017 | J. Infect. Dis. | pmid:27578848 |
| Romero L et al. | Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults. | 2017 | Cochrane Database Syst Rev | pmid:29226307 |
| Dror T et al. | Microbiota manipulation for weight change. | 2017 | Microb. Pathog. | pmid:26792677 |
| Lusk MJ et al. | Cervicitis: a prospective observational study of empiric azithromycin treatment in women with cervicitis and non-specific cervicitis. | 2017 | Int J STD AIDS | pmid:26792283 |
| Marks M and Mabey D | Single-dose azithromycin to treat latent yaws. | 2017 | Lancet Glob Health | pmid:29107622 |
| Halhal B et al. | Pertussis Outbreak Among Soldiers During Basic Training: The Need for Updated Protocols. | 2017 | Mil Med | pmid:28291499 |
| Çelik Payçu DG and Büyükbaba Boral Ö | [Effects of azithromycin and Chlorella vulgaris treatment on certain cytokine values and NK cell activity in an acute murine toxoplasmosis model]. | 2017 | Mikrobiyol Bul | pmid:28283010 |