Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lynch M et al. | Azithromycin treatment coverage in Tanzanian children using community volunteers. | 2003 | Ophthalmic Epidemiol | pmid:12815491 |
| Tyteca D et al. | The macrolide antibiotic azithromycin interacts with lipids and affects membrane organization and fluidity: studies on Langmuir-Blodgett monolayers, liposomes and J774 macrophages. | 2003 | J. Membr. Biol. | pmid:12820665 |
| Taylor WR et al. | Tolerability of azithromycin as malaria prophylaxis in adults in northeast papua, indonesia. | 2003 | Antimicrob. Agents Chemother. | pmid:12821468 |
| Seral C et al. | Quantitative analysis of gentamicin, azithromycin, telithromycin, ciprofloxacin, moxifloxacin, and oritavancin (LY333328) activities against intracellular Staphylococcus aureus in mouse J774 macrophages. | 2003 | Antimicrob. Agents Chemother. | pmid:12821480 |
| Bingen E et al. | Activity of telithromycin against penicillin-resistant Streptococcus pneumoniae isolates recovered from French children with invasive and noninvasive infections. | 2003 | Antimicrob. Agents Chemother. | pmid:12821495 |
| Cone LA et al. | Delirium in the elderly resulting from azithromycin therapy. | 2003 | Surg Neurol | pmid:12826358 |
| Nigović B and Simunić B | Voltammetric assay of azithromycin in pharmaceutical dosage forms. | 2003 | J Pharm Biomed Anal | pmid:12852463 |
| Bhattacharya MK et al. | Azithromycin in the treatment of cholera in children. | 2003 | Acta Paediatr. | pmid:12856976 |
| Rush C and Simon MW | The effect of amoxicillin-clavulanate, cefixime and azithromycin on normal throat flora in children with group A streptococcal pharyngitis. | 2003 | Clin Pediatr (Phila) | pmid:12862350 |
| Lildholdt T et al. | The natural history of recurrent acute tonsillitis and a clinical trial of azithromycin for antibiotic prophylaxis. | 2003 | Clin Otolaryngol Allied Sci | pmid:12871256 |
| Rodvold KA et al. | Steady-state plasma and bronchopulmonary concentrations of intravenous levofloxacin and azithromycin in healthy adults. | 2003 | Antimicrob. Agents Chemother. | pmid:12878504 |
| Dunne MW et al. | Efficacy of single-dose azithromycin in treatment of acute otitis media in children after a baseline tympanocentesis. | 2003 | Antimicrob. Agents Chemother. | pmid:12878537 |
| Crum NF et al. | Halting a pneumococcal pneumonia outbreak among United States Marine Corps trainees. | 2003 | Am J Prev Med | pmid:12880877 |
| Feldman RB et al. | Azithromycin monotherapy for patients hospitalized with community-acquired pneumonia: a 31/2-year experience from a veterans affairs hospital. | 2003 | Arch. Intern. Med. | pmid:12885688 |
| Garasiuta EG | [Surgical treatment of ulnar and pre-patellar bursitis under ambulatory conditions]. | 2000 | Voen Med Zh | pmid:12886538 |
| Dunne MW et al. | Randomized, double-blind study of the clinical efficacy of 3 days of azithromycin compared with co-amoxiclav for the treatment of acute otitis media. | 2003 | J. Antimicrob. Chemother. | pmid:12888586 |
| Falk L et al. | Tetracycline treatment does not eradicate Mycoplasma genitalium. | 2003 | Sex Transm Infect | pmid:12902584 |
| Strachan D et al. | Is oral azithromycin effective for the treatment of cyclosporine-induced gingival hyperplasia in cardiac transplant recipients? | 2003 | J Clin Pharm Ther | pmid:12911686 |
| Sosa J et al. | High percentages of resistance to tetracycline and penicillin and reduced susceptibility to azithromycin characterize the majority of strain types of Neisseria gonorrhoeae isolates in Cuba, 1995-1998. | 2003 | Sex Transm Dis | pmid:12916137 |
| Sahin-Hodoglugil NN et al. | A comparison of cost-effectiveness of three protocols for diagnosis and treatment of gonococcal and chlamydial infections in women in Africa. | 2003 | Sex Transm Dis | pmid:12916139 |
| Laming AC and Currie BJ | An evaluation of a SAFE-style trachoma control program in central Australia. | 2003 | Med. J. Aust. | pmid:12921100 |
| Ohsaki Y et al. | Alterations in penicillin binding protein gene of Streptococcus pneumoniae and their correlation with susceptibility patterns. | 2003 | Int. J. Antimicrob. Agents | pmid:12927954 |
| Zhou LQ et al. | [Detection of bacterial 16S rRAN gene in EPS of men with chronic pelvic pain syndrome and its clinical significance]. | 2003 | Zhonghua Nan Ke Xue | pmid:12931366 |
| Batt SL et al. | Impact of azithromycin administration for trachoma control on the carriage of antibiotic-resistant Streptococcus pneumoniae. | 2003 | Antimicrob. Agents Chemother. | pmid:12936971 |
| Henry DC et al. | Randomized double-blind study comparing 3- and 6-day regimens of azithromycin with a 10-day amoxicillin-clavulanate regimen for treatment of acute bacterial sinusitis. | 2003 | Antimicrob. Agents Chemother. | pmid:12936972 |
| Sirinavin S et al. | Norfloxacin and azithromycin for treatment of nontyphoidal salmonella carriers. | 2003 | Clin. Infect. Dis. | pmid:12942401 |
| Matsuzaki K et al. | [Susceptibility of major pathogens of acute pharyngitis and tonsillitis to levofloxacin and other oral antimicrobial drugs]. | 2003 | Jpn J Antibiot | pmid:12942788 |
| DeÄŸerli K et al. | Efficacy of azithromycin in a murine toxoplasmosis model, employing a Toxoplasma gondii strain from Turkey. | 2003 | Acta Trop. | pmid:12943976 |
| Favre-Bonté S et al. | Biofilm formation by Pseudomonas aeruginosa: role of the C4-HSL cell-to-cell signal and inhibition by azithromycin. | 2003 | J. Antimicrob. Chemother. | pmid:12951348 |
| Rocha JL | Correct dose of azithromycin for patients scheduled to undergo dental procedures. | 2003 | Clin. Infect. Dis. | pmid:12955653 |
| Abdelghaffar H et al. | Interaction of macrolides and ketolides with the phagocytic cell line PLB-985. | 2003 | J Chemother | pmid:12962363 |
| Sugihara E et al. | Macrolide antibiotics directly reduce active oxygen generation by neutrophils in human peripheral blood. | 2003 | Kurume Med J | pmid:12971257 |
| Miguel L and Barbas C | LC determination of impurities in azithromycin tablets. | 2003 | J Pharm Biomed Anal | pmid:12972086 |
| Fernández Cuenca F et al. | [In vitro activity of azithromycin against clinical isolates of Acinetobacter baumannii]. | 2003 | Rev Esp Quimioter | pmid:12973458 |
| Huang C et al. | Susceptibility of mixed infection of Ureaplasma Urealyticum and Mycoplasma Hominis to seven antimicrobial agents and comparison with that of Ureaplasma Urealyticum infection. | 2003 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:12973952 |
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| O'Connor CM et al. | Azithromycin for the secondary prevention of coronary heart disease events: the WIZARD study: a randomized controlled trial. | 2003 | JAMA | pmid:13129985 |
| Massarotti EM et al. | Treatment of early Lyme disease. | 1992 | Am. J. Med. | pmid:1313637 |
| Pruul H and McDonald PJ | Potentiation of antibacterial activity of azithromycin and other macrolides by normal human serum. | 1992 | Antimicrob. Agents Chemother. | pmid:1317141 |
| Brown BA et al. | Activities of four macrolides, including clarithromycin, against Mycobacterium fortuitum, Mycobacterium chelonae, and M. chelonae-like organisms. | 1992 | Antimicrob. Agents Chemother. | pmid:1317144 |
| Kobrehel G et al. | Synthesis and antibacterial activity of O-methylazithromycin derivatives. | 1992 | J. Antibiot. | pmid:1317368 |
| Welsh LE et al. | In vitro evaluation of activities of azithromycin, erythromycin, and tetracycline against Chlamydia trachomatis and Chlamydia pneumoniae. | 1992 | Antimicrob. Agents Chemother. | pmid:1318677 |
| Bahal N and Nahata MC | The new macrolide antibiotics: azithromycin, clarithromycin, dirithromycin, and roxithromycin. | 1992 | Ann Pharmacother | pmid:1318761 |
| Drew RH and Gallis HA | Azithromycin--spectrum of activity, pharmacokinetics, and clinical applications. | 1992 | Pharmacotherapy | pmid:1319048 |
| Chave JP et al. | Once-a-week azithromycin in AIDS patients: tolerability, kinetics, and effects on zidovudine disposition. | 1992 | Antimicrob. Agents Chemother. | pmid:1324635 |
| Derouin F et al. | Synergistic activity of azithromycin and pyrimethamine or sulfadiazine in acute experimental toxoplasmosis. | 1992 | Antimicrob. Agents Chemother. | pmid:1324642 |
| Vallée E et al. | Activity and local delivery of azithromycin in a mouse model of Haemophilus influenzae lung infection. | 1992 | Antimicrob. Agents Chemother. | pmid:1324644 |
| Mertens JC et al. | Double-blind randomized study comparing the efficacies and safeties of a short (3-day) course of azithromycin and a 5-day course of amoxicillin in patients with acute exacerbations of chronic bronchitis. | 1992 | Antimicrob. Agents Chemother. | pmid:1324645 |
| Hammerschlag MR et al. | In vitro activities of azithromycin, clarithromycin, L-ofloxacin, and other antibiotics against Chlamydia pneumoniae. | 1992 | Antimicrob. Agents Chemother. | pmid:1324650 |
| Paulsen P et al. | Influence of azithromycin and other macrolides on the intracellular killing of Staphylococcus aureus by human polymorphonuclear leucocytes of healthy donors and a patient with Chédiak-Higashi syndrome. | 1992 | Chemotherapy | pmid:1324831 |