Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Li Y et al. | Where macrolide resistance is prevalent. | 2015 | APMIS | pmid:25703275 |
| Kärpänoja P et al. | Antimicrobial susceptibility testing of Streptococcus pneumoniae and Haemophilus influenzae --internal quality control as a quality tool on a national level. | 2013 | APMIS | pmid:23163534 |
| Petrini B | Mycobacterium abscessus: an emerging rapid-growing potential pathogen. | 2006 | APMIS | pmid:16725007 |
| Zavadska D et al. | Macrolide resistance in group A beta haemolytic Streptococcus isolated from outpatient children in Latvia. | 2010 | APMIS | pmid:20477812 |
| Lundbäck D et al. | Molecular epidemiology of Neisseria gonorrhoeae- identification of the first presumed Swedish transmission chain of an azithromycin-resistant strain. | 2006 | APMIS | pmid:16499664 |
| Drago L et al. | Kinetic bactericidal activity of telithromycin, azithromycin and clarithromycin against respiratory pathogens. | 2005 | APMIS | pmid:16309423 |
| Mustapha NA et al. | Impact of different antibiotics on methane production using waste-activated sludge: mechanisms and microbial community dynamics. | 2016 | Appl. Microbiol. Biotechnol. | pmid:27531514 |
| Melski JW et al. | Primary and secondary erythema migrans in central Wisconsin. | 1993 | Arch Dermatol | pmid:8389536 |
| Fernandez-Obregon A | Oral use of azithromycin for the treatment of acne rosacea. | 2004 | Arch Dermatol | pmid:15096385 |
| Wertman R et al. | Mycobacterium bolletii/Mycobacterium massiliense furunculosis associated with pedicure footbaths: a report of 3 cases. | 2011 | Arch Dermatol | pmid:21482895 |
| McConnell K and Shields M | Azithromycin for episodes with asthma-like symptoms in young children aged 1-3 years. | 2017 | Arch Dis Child Educ Pract Ed | pmid:28735295 |
| Magri V et al. | Reduction of PSA values by combination pharmacological therapy in patients with chronic prostatitis: implications for prostate cancer detection. | 2007 | Arch Ital Urol Androl | pmid:17695414 |
| Magri V et al. | Eradication of unusual pathogens by combination pharmacological therapy is paralleled by improvement of signs and symptoms of chronic prostatitis syndrome. | 2007 | Arch Ital Urol Androl | pmid:17695415 |
| Grand A et al. | [Subacute infectious endocarditis due to the agent of cat scratch fever: Bartonella henselae]. | 2001 | Arch Mal Coeur Vaiss | pmid:11265556 |
| Guillot M et al. | [Macrolides, Pseudomonas aeruginosa and cystic fibrosis]. | 2006 | Arch Pediatr | pmid:17370396 |
| Mandelcwajg A et al. | [Mediterranean spotted fever in a 3-year-old child]. | 2014 | Arch Pediatr | pmid:24630621 |
| Derelle J | [Anti-inflammatory therapy in cystic fibrosis]. | 2003 | Arch Pediatr | pmid:14671937 |
| Caillet-Gossot S et al. | [Clustered cases of intrafamily invasive Streptococcus pyogenes infection (or group A streptococcus)]. | 2011 | Arch Pediatr | pmid:22056211 |
| Bingen E | [Antibiotic resistance of bacterial strains in paediatric infections: there are resistance and resistance!]. | 2008 | Arch Pediatr | pmid:19000854 |
| Gendrel D and Cohen R | [Bacterial diarrheas and antibiotics: European recommendations]. | 2008 | Arch Pediatr | pmid:19000862 |
| Floret D et al. | [Action to be taken when facing one or more cases of whooping-cough]. | 2005 | Arch Pediatr | pmid:15961299 |
| Cohen R and Grimprel E | [Rational and irrational of azithromycin use]. | 2013 | Arch Pediatr | pmid:24360299 |
| Amer A et al. | The natural history of pityriasis rosea in black American children: how correct is the "classic" description? | 2007 | Arch Pediatr Adolesc Med | pmid:17485628 |
| Steinberg JM and Srugo I | Reoccurrence of culture-positive pertussis in an infant initially treated with azithromycin and steroids. | 2002 | Arch Pediatr Adolesc Med | pmid:12361458 |
| Angelilli ML et al. | Palatability of oral antibiotics among children in an urban primary care center. | 2000 | Arch Pediatr Adolesc Med | pmid:10710025 |
| McPhail GL et al. | Improving evidence-based care in cystic fibrosis through quality improvement. | 2010 | Arch Pediatr Adolesc Med | pmid:20921354 |
| Casas-Maldonado F | Bronchiectasis and Azithromycin. | 2018 | Arch. Bronconeumol. | pmid:28757281 |
| Méndez Abad P et al. | Idiopathic plastic bronchitis as an uncommon cause of massive pulmonary atelectasis. | 2015 | Arch. Bronconeumol. | pmid:24495947 |
| Máiz Carro L | [Long-term treatment with azithromycin in a patient with idiopathic bronchiectasis]. | 2005 | Arch. Bronconeumol. | pmid:15919012 |
| Espadas D et al. | Lack of effect of azithromycin on QT interval in children: a cohort study. | 2016 | Arch. Dis. Child. | pmid:27515186 |
| Turner MA et al. | Azithromycin, Ureaplasma and chronic lung disease of prematurity: a case study for neonatal drug development. | 2012 | Arch. Dis. Child. | pmid:21697219 |
| Srinivasan R and Yeo TH | Are newer macrolides effective in eradicating carriage of pertussis? | 2005 | Arch. Dis. Child. | pmid:15723933 |
| Kirk CB | Is the frequency of recurrent chest infections, in children with chronic neurological problems, reduced by prophylactic azithromycin? | 2008 | Arch. Dis. Child. | pmid:17908711 |
| Chin LK et al. | Pertussis encephalopathy in an infant. | 2013 | Arch. Dis. Child. | pmid:23251014 |
| Sharma JB et al. | Comparative efficacy of two regimens in syndromic management of lower genital infections. | 2006 | Arch. Gynecol. Obstet. | pmid:16247610 |
| Guven MA et al. | The demographic and behavioural profile of women with cervicitis infected with Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum and the comparison of two medical regimens. | 2005 | Arch. Gynecol. Obstet. | pmid:15778862 |
| Dooley DP | Revisiting doxycycline. | 1998 | Arch. Intern. Med. | pmid:9665360 |
| Feldman RB et al. | Azithromycin monotherapy for patients hospitalized with community-acquired pneumonia: a 31/2-year experience from a veterans affairs hospital. | 2003 | Arch. Intern. Med. | pmid:12885688 |
| Vergis EN et al. | Azithromycin vs cefuroxime plus erythromycin for empirical treatment of community-acquired pneumonia in hospitalized patients: a prospective, randomized, multicenter trial. | 2000 | Arch. Intern. Med. | pmid:10809032 |
| Malcolm C and Marrie TJ | Antibiotic therapy for ambulatory patients with community-acquired pneumonia in an emergency department setting. | 2003 | Arch. Intern. Med. | pmid:12695270 |
| Silvers JA and Champney WS | Accumulation and turnover of 23S ribosomal RNA in azithromycin-inhibited ribonuclease mutant strains of Escherichia coli. | 2005 | Arch. Microbiol. | pmid:16096836 |
| Lin C and Lietman T | Trachoma control: is azithromycin the answer for trichiasis too? | 2007 | Arch. Ophthalmol. | pmid:17562994 |
| Woreta F et al. | Three-year outcomes of the surgery for trichiasis, antibiotics to prevent recurrence trial. | 2012 | Arch. Ophthalmol. | pmid:22159169 |
| West SK et al. | Single-dose azithromycin prevents trichiasis recurrence following surgery: randomized trial in Ethiopia. | 2006 | Arch. Ophthalmol. | pmid:16534049 |
| Taylor HR | Misleading titles cause confusion. | 2009 | Arch. Ophthalmol. | pmid:19204251 |
| Rudich DS and Bhatnagar P | Scleritis associated with toxoplasmic retinochoroiditis. | 2012 | Arch. Ophthalmol. | pmid:22652859 |
| Sommer A | Systemic antibiotics for communitywide trachoma control. | 2005 | Arch. Ophthalmol. | pmid:15883291 |
| Tabbara KF et al. | Ocular levels of azithromycin. | 1998 | Arch. Ophthalmol. | pmid:9869792 |
| Keenan JD et al. | Slow resolution of clinically active trachoma following successful mass antibiotic treatments. | 2011 | Arch. Ophthalmol. | pmid:21482879 |
| Woreta TA et al. | Effect of trichiasis surgery on visual acuity outcomes in Ethiopia. | 2009 | Arch. Ophthalmol. | pmid:19901217 |