Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tkadlec J et al. | Characterization of Staphylococcus aureus Strains Isolated from Czech Cystic Fibrosis Patients: High Rate of Ribosomal Mutation Conferring Resistance to MLS(B) Antibiotics as a Result of Long-Term and Low-Dose Azithromycin Treatment. | 2015 | Microb. Drug Resist. | pmid:25826283 |
| Weinberger M et al. | Diffuse panbronchiolitis in a 10-year-old boy. | 2015 | Pediatr. Pulmonol. | pmid:25824890 |
| Dave J and Sefton A | Enteric fever and its impact on returning travellers. | 2015 | Int Health | pmid:25808163 |
| Li X et al. | Preparation and characterization of azithromycin--Aerosil 200 solid dispersions with enhanced physical stability. | 2015 | Int J Pharm | pmid:25794608 |
| da Cunha Filho RR et al. | Acute generalized exanthematous pustulosis by azithromycin. | 2015 | Int. J. Dermatol. | pmid:25784092 |
| Bala M et al. | Trends of resistance to antimicrobials recommended currently and in the past for management of gonorrhea in the Apex STD center in India and comparison of antimicrobial resistance profile between 2002-2006 and 2007-2012. | 2015 | Sex Transm Dis | pmid:25763675 |
| Laopaiboon M et al. | Azithromycin for acute lower respiratory tract infections. | 2015 | Cochrane Database Syst Rev | pmid:25749735 |
| Moi H et al. | Spontaneous Regression of Untreatable Mycoplasma genitalium Urethritis. | 2015 | Acta Derm. Venereol. | pmid:25634824 |
| Hicks LA et al. | US outpatient antibiotic prescribing variation according to geography, patient population, and provider specialty in 2011. | 2015 | Clin. Infect. Dis. | pmid:25747410 |
| Ghinai R et al. | A cross-sectional study of 'yaws' in districts of Ghana which have previously undertaken azithromycin mass drug administration for trachoma control. | 2015 | PLoS Negl Trop Dis | pmid:25632942 |
| Walsh MS et al. | Prevalence of Chlamydia trachomatis infection in Samoan women aged 18 to 29 and assessment of possible risk factors: a community-based study. | 2015 | Trans. R. Soc. Trop. Med. Hyg. | pmid:25732755 |
| Hamasuna R et al. | The second nationwide surveillance of the antimicrobial susceptibility of Neisseria gonorrhoeae from male urethritis in Japan, 2012-2013. | 2015 | J. Infect. Chemother. | pmid:25727286 |
| Gershengorn HB et al. | The association of antibiotic treatment regimen and hospital mortality in patients hospitalized with Legionella pneumonia. | 2015 | Clin. Infect. Dis. | pmid:25722195 |
| Pettus K et al. | In vitro assessment of dual drug combinations to inhibit growth of Neisseria gonorrhoeae. | 2015 | Antimicrob. Agents Chemother. | pmid:25624328 |
| Hildebrand F et al. | Efficacy of gamithromycin for the treatment of foals with mild to moderate bronchopneumonia. | 2015 | J. Vet. Intern. Med. | pmid:25619521 |
| Denlinger CE | Matrix metalloproteinases and bronchiolitis obliterans: Wrapping the enigma in a riddle. | 2015 | J. Thorac. Cardiovasc. Surg. | pmid:25618413 |
| Khosropour CM et al. | Efficacy of standard therapies against Ureaplasma species and persistence among men with non-gonococcal urethritis enrolled in a randomised controlled trial. | 2015 | Sex Transm Infect | pmid:25616607 |
| Liu Y et al. | Can tetracycline antibiotics duplicate the ability of azithromycin to stimulate human meibomian gland epithelial cell differentiation? | 2015 | Cornea | pmid:25611398 |
| Chen M et al. | Azithromycin attenuates cigarette smoke extract-induced oxidative stress injury in human alveolar epithelial cells. | 2015 | Mol Med Rep | pmid:25607112 |
| Sutton AL et al. | Perinatal pharmacokinetics of azithromycin for cesarean prophylaxis. | 2015 | Am. J. Obstet. Gynecol. | pmid:25595580 |
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| Solleti VS et al. | Antimicrobial properties of liposomal azithromycin for Pseudomonas infections in cystic fibrosis patients. | 2015 | J. Antimicrob. Chemother. | pmid:25416744 |
| Chou HW et al. | Risks of cardiac arrhythmia and mortality among patients using new-generation macrolides, fluoroquinolones, and β-lactam/β-lactamase inhibitors: a Taiwanese nationwide study. | 2015 | Clin. Infect. Dis. | pmid:25409476 |
| Bauquier JR et al. | Anti-inflammatory effects of four potential anti-endotoxaemic drugs assessed in vitro using equine whole blood assays. | 2015 | J. Vet. Pharmacol. Ther. | pmid:25407884 |
| Jeong BH et al. | Intermittent antibiotic therapy for nodular bronchiectatic Mycobacterium avium complex lung disease. | 2015 | Am. J. Respir. Crit. Care Med. | pmid:25393520 |
| Bissessor M et al. | Persistence of Neisseria gonorrhoeae DNA following treatment for pharyngeal and rectal gonorrhea is influenced by antibiotic susceptibility and reinfection. | 2015 | Clin. Infect. Dis. | pmid:25371490 |
| Chi KH et al. | Molecular differentiation of Treponema pallidum subspecies in skin ulceration clinically suspected as yaws in Vanuatu using real-time multiplex PCR and serological methods. | 2015 | Am. J. Trop. Med. Hyg. | pmid:25404075 |
| Merchan LM et al. | Pharmacokinetics, microbial response, and pulmonary outcomes of multidose intravenous azithromycin in preterm infants at risk for Ureaplasma respiratory colonization. | 2015 | Antimicrob. Agents Chemother. | pmid:25385115 |
| Nonaka L et al. | Novel macrolide-resistance genes, mef(C) and mph(G), carried by plasmids from Vibrio and Photobacterium isolated from sediment and seawater of a coastal aquaculture site. | 2015 | Lett. Appl. Microbiol. | pmid:25765542 |
| Cocco G and Jerie P | Torsades de pointes induced by the concomitant use of ivabradine and azithromycin: an unexpected dangerous interaction. | 2015 | Cardiovasc. Toxicol. | pmid:25158669 |
| Kashkouli MB et al. | Oral azithromycin versus doxycycline in meibomian gland dysfunction: a randomised double-masked open-label clinical trial. | 2015 | Br J Ophthalmol | pmid:25138765 |
| Gundevia Z et al. | Positivity at test of cure following first-line treatment for genital Mycoplasma genitalium: follow-up of a clinical cohort. | 2015 | Sex Transm Infect | pmid:25096921 |
| Hussain S et al. | N-acetylcysteine and azithromycin affect the innate immune response in cystic fibrosis bronchial epithelial cells in vitro. | 2015 | Exp. Lung Res. | pmid:25058850 |
| Sandrock CE and Norris A | Infection in severe asthma exacerbations and critical asthma syndrome. | 2015 | Clin Rev Allergy Immunol | pmid:24984968 |
| Aucamp M et al. | Amorphous azithromycin with improved aqueous solubility and intestinal membrane permeability. | 2015 | Drug Dev Ind Pharm | pmid:24980913 |
| Martinez MA et al. | Clinical and histologic features of azithromycin-induced liver injury. | 2015 | Clin. Gastroenterol. Hepatol. | pmid:25111234 |
| Cabeza J et al. | Feasibility of Chlamydia trachomatis screening and treatment in pregnant women in Lima, Peru: a prospective study in two large urban hospitals. | 2015 | Sex Transm Infect | pmid:25107711 |
| Ratjen F et al. | Response to letter. | 2015 | Pediatr. Pulmonol. | pmid:24700677 |
| Tayob N and Murray S | Nonparametric tests of treatment effect based on combined endpoints for mortality and recurrent events. | 2015 | Biostatistics | pmid:24719282 |
| Salman S et al. | Pharmacokinetics of Transfer of Azithromycin into the Breast Milk of African Mothers. | 2015 | Antimicrob. Agents Chemother. | pmid:26711756 |
| Geisler WM et al. | Azithromycin versus Doxycycline for Urogenital Chlamydia trachomatis Infection. | 2015 | N. Engl. J. Med. | pmid:26699167 |
| Smith C et al. | Use and safety of azithromycin in neonates: a systematic review. | 2015 | BMJ Open | pmid:26656010 |
| Solomon AW et al. | Trachoma and Yaws: Common Ground? | 2015 | PLoS Negl Trop Dis | pmid:26633176 |
| RuÃz del Olmo I et al. | [Severe neutropenia as side effect of medical treatment in nontuberculous mycobacterial adenitis]. | 2015 | Rev Chilena Infectol | pmid:26633119 |
| Woodruff AE et al. | Azithromycin-Induced, Biopsy-Proven Acute Interstitial Nephritis in an Adult Successfully Treated with Low-Dose Corticosteroids. | 2015 | Pharmacotherapy | pmid:26598102 |
| Jensen EA et al. | Evidence-Based Pharmacologic Therapies for Prevention of Bronchopulmonary Dysplasia: Application of the Grading of Recommendations Assessment, Development, and Evaluation Methodology. | 2015 | Clin Perinatol | pmid:26593077 |
| Fan WG et al. | Male Paraurethral Duct Infection and Subsequent Paraurethral Duct Dilation. | 2015 | Chin. Med. J. | pmid:26608997 |
| Wise J | Early use of azithromycin may reduce severity of wheezing, study finds. | 2015 | BMJ | pmid:26582751 |
| MaraÄić S et al. | 1,2,3-Triazole pharmacophore-based benzofused nitrogen/sulfur heterocycles with potential anti-Moraxella catarrhalis activity. | 2015 | Bioorg. Med. Chem. | pmid:26578325 |
| Zhang B et al. | Azithromycin drives alternative macrophage activation and improves recovery and tissue sparing in contusion spinal cord injury. | 2015 | J Neuroinflammation | pmid:26597676 |
| Cohen RT and Pelton SI | Individual Benefit vs Societal Effect of Antibiotic Prescribing for Preschool Children With Recurrent Wheeze. | 2015 | JAMA | pmid:26575058 |
| Roca A et al. | Prevention of bacterial infections in the newborn by pre-delivery administration of azithromycin: Study protocol of a randomized efficacy trial. | 2015 | BMC Pregnancy Childbirth | pmid:26585192 |
| Bacharier LB et al. | Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial. | 2015 | JAMA | pmid:26575060 |
| Trembizki E et al. | Direct real-time PCR-based detection of Neisseria gonorrhoeae 23S rRNA mutations associated with azithromycin resistance. | 2015 | J. Antimicrob. Chemother. | pmid:26338048 |
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| Marks M et al. | Impact of Community Mass Treatment with Azithromycin for Trachoma Elimination on the Prevalence of Yaws. | 2015 | PLoS Negl Trop Dis | pmid:26241484 |
| Stellari F et al. | In vivo imaging of the lung inflammatory response to Pseudomonas aeruginosa and its modulation by azithromycin. | 2015 | J Transl Med | pmid:26239109 |
| Taylor SP et al. | Azithromycin for the Prevention of COPD Exacerbations: The Good, Bad, and Ugly. | 2015 | Am. J. Med. | pmid:26291905 |
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| Wetherbee EE et al. | Self-reported alcohol intake and risk of acute exacerbations of chronic obstructive pulmonary disease: a prospective cohort study. | 2015 | Int J Chron Obstruct Pulmon Dis | pmid:26229455 |
| Moi H et al. | Management of non-gonococcal urethritis. | 2015 | BMC Infect. Dis. | pmid:26220178 |
| Kong FY and Hocking JS | Treatment challenges for urogenital and anorectal Chlamydia trachomatis. | 2015 | BMC Infect. Dis. | pmid:26220080 |
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| Beigelman A et al. | Does azithromycin modify viral load during severe respiratory syncytial virus bronchiolitis? | 2015 | J. Allergy Clin. Immunol. | pmid:26215052 |
| Pereira A et al. | Acute onset of widespread pustular eruption. | 2015 | Aust Fam Physician | pmid:26209988 |
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| Kirby A | Comment on: Clinical cure rates in subjects treated with azithromycin for community-acquired respiratory tract infections caused by azithromycin-susceptible or azithromycin-resistant Streptococcus pneumoniae: analysis of Phase 3 clinical trial data. | 2015 | J. Antimicrob. Chemother. | pmid:26157112 |
| Furfaro LL et al. | In vitro activity of solithromycin and its metabolites, CEM-214 and N-acetyl-CEM-101, against 100 clinical Ureaplasma spp. isolates compared with azithromycin. | 2015 | Int. J. Antimicrob. Agents | pmid:26141231 |
| Farber FR et al. | Atraumatic splenic rupture from Babesia: A disease of the otherwise healthy patient. | 2015 | Ticks Tick Borne Dis | pmid:26123434 |
| Ahmed N et al. | Donovanosis causing lymphadenitis, mastoiditis, and meningitis in a child. | 2015 | Lancet | pmid:26122163 |
| Barni S et al. | Azithromycin is more allergenic than clarithromycin in children with suspected hypersensitivity reaction to macrolides. | 2015 | J Investig Allergol Clin Immunol | pmid:25997306 |
| Jo KW et al. | The efficacy of prophylactic azithromycin on bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation. | 2015 | Int. J. Hematol. | pmid:26121954 |
| Earl CS et al. | Haemophilus influenzae responds to glucocorticoids used in asthma therapy by modulation of biofilm formation and antibiotic resistance. | 2015 | EMBO Mol Med | pmid:25995336 |
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| Qin YH et al. | Transdermal application of azithromycin-amlodipine-heparin gel enhances survival of infected random ischaemic flap. | 2015 | J Plast Surg Hand Surg | pmid:26083309 |
| Lietman TM et al. | The distribution of the prevalence of ocular chlamydial infection in communities where trachoma is disappearing. | 2015 | Epidemics | pmid:25979286 |
| Missov E and Cogswell R | Sudden cardiac death, mitral valve prolapse, and long QT syndrome. | 2015 | Am. J. Med. | pmid:26071830 |
| Buset SL et al. | Non-surgical periodontal therapy supplemented with systemically administered azithromycin: a systematic review of RCTs. | 2015 | Clin Oral Investig | pmid:26063646 |
| Hauser G et al. | Probiotics for standard triple Helicobacter pylori eradication: a randomized, double-blind, placebo-controlled trial. | 2015 | Medicine (Baltimore) | pmid:25929897 |
| Yin SM et al. | Disseminated Mycobacterium kansasii disease in complete DiGeorge syndrome. | 2015 | J. Clin. Immunol. | pmid:26048260 |
| Craig AP et al. | Is it time to switch to doxycycline from azithromycin for treating genital chlamydial infections in women? Modelling the impact of autoinoculation from the gastrointestinal tract to the genital tract. | 2015 | BMC Infect. Dis. | pmid:25925662 |
| Cusini M | Therapy for Gonococcal and Non-gonococcal Genital Infections is a Major Problem for Clinicians. | 2015 | Acta Derm. Venereol. | pmid:25917593 |
| Harding-Esch E et al. | Costs of testing for ocular Chlamydia trachomatis infection compared to mass drug administration for trachoma in the Gambia: application of results from the PRET study. | 2015 | PLoS Negl Trop Dis | pmid:25901349 |
| Rudoler N et al. | Comparison of the acute phase protein and antioxidant responses in dogs vaccinated against canine monocytic ehrlichiosis and naive-challenged dogs. | 2015 | Parasit Vectors | pmid:25888870 |
| Chandra R et al. | Comparison of azithromycin plus chloroquine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in children in Africa: a randomized, open-label study. | 2015 | Malar. J. | pmid:25881046 |
| Schroeck JL et al. | Factors associated with antibiotic misuse in outpatient treatment for upper respiratory tract infections. | 2015 | Antimicrob. Agents Chemother. | pmid:25870064 |
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| Waites KB et al. | In vitro antibacterial activity of AZD0914 against human Mycoplasmas and Ureaplasmas. | 2015 | Antimicrob. Agents Chemother. | pmid:25824220 |