Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Urinary Tract Infections D014552 11 associated lipids
Urticaria D014581 13 associated lipids
Vertigo D014717 4 associated lipids
Vomiting D014839 21 associated lipids
Whooping Cough D014917 6 associated lipids
Wound Infection D014946 12 associated lipids
Yaws D015001 4 associated lipids
Superinfection D015163 3 associated lipids
Sexually Transmitted Diseases, Bacterial D015231 5 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Weight Gain D015430 101 associated lipids
Weight Loss D015431 56 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
Frontal Sinusitis D015522 1 associated lipids
Corneal Edema D015715 3 associated lipids
Erythema Chronicum Migrans D015787 3 associated lipids
Uveitis, Intermediate D015867 3 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Helicobacter Infections D016481 21 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Vaginosis, Bacterial D016585 10 associated lipids
Pneumocystis Infections D016720 1 associated lipids
Leishmaniasis, Cutaneous D016773 6 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Common Variable Immunodeficiency D017074 4 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Pelvic Pain D017699 7 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Furcation Defects D017823 1 associated lipids
T-Lymphocytopenia, Idiopathic CD4-Positive D018344 1 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Parasitemia D018512 5 associated lipids
Abdominal Abscess D018784 2 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Pseudolymphoma D019310 1 associated lipids
Pouchitis D019449 3 associated lipids
Syncope, Vasovagal D019462 1 associated lipids
Acquired Hyperostosis Syndrome D020083 1 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Focal Nodular Hyperplasia D020518 1 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Burton MJ et al. Azithromycin for the treatment and control of trachoma. 2002 Expert Opin Pharmacother pmid:11829725
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Skerk V et al. Azithromycin and doxycycline in the treatment of female patients with acute urethral syndrome caused by Ureaplasma urealyticum: significance of duration of clinical symptoms. 2001 Drugs Exp Clin Res pmid:11822223
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Lentino JR and Krasnicka B Association between initial empirical therapy and decreased length of stay among veteran patients hospitalized with community acquired pneumonia. 2002 Int. J. Antimicrob. Agents pmid:11814769
Zubata P et al. A new HPLC method for azithromycin quantitation. 2002 J Pharm Biomed Anal pmid:11814725
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Skerk V et al. Azithromycin in the treatment of chronic prostatitis caused by Chlamydia trachomatis. 2001 J Chemother pmid:11806631
Nagai K et al. Susceptibility to telithromycin in 1,011 Streptococcus pyogenes isolates from 10 central and Eastern European countries. 2002 Antimicrob. Agents Chemother. pmid:11796375
Kutlin A et al. Effect of prolonged treatment with azithromycin, clarithromycin, or levofloxacin on Chlamydia pneumoniae in a continuous-infection Model. 2002 Antimicrob. Agents Chemother. pmid:11796350
van der Griend B et al. An uncommon cause of a destructive vulval lesion. 2001 Aust N Z J Obstet Gynaecol pmid:11787928
Oksi J [Diagnostics and treatment of Lyme borreliosis]. 2000 Duodecim pmid:11787113
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Mendes CM et al. In vitro susceptibility of gram-positive cocci isolated from skin and respiratory tract to azithromycin and twelve other antimicrobial agents. 2001 Braz J Infect Dis pmid:11779453
Phillips P et al. Azithromycin prophylaxis for Mycobacterium avium complex during the era of highly active antiretroviral therapy: evaluation of a provincial program. 2002 Clin. Infect. Dis. pmid:11774085
Swanston WH et al. Single dose (direct observed) azithromycin therapy for Neisseria gonorrhoeae and Chlamydia trachomatis in STD clinic attenders with genital discharge in Trinidad and Tobago. 2001 West Indian Med J pmid:11769023
Bragina EY et al. Electron microscopic evidence of persistent chlamydial infection following treatment. 2001 J Eur Acad Dermatol Venereol pmid:11763379
Jacks S et al. Pharmacokinetics of azithromycin and concentration in body fluids and bronchoalveolar cells in foals. 2001 Am. J. Vet. Res. pmid:11763173
Chodorowska M et al. [Susceptibility to macrolide antibiotics of Bordetella pertussis and Bordetella parapertussis strains isolated from whooping cough patients in 1968 and in 1997-99]. 2001 Med Dosw Mikrobiol pmid:11757403
Firsov AA et al. Comparative pharmacodynamics of azithromycin and roxithromycin with S. pyogenes and S. pneumoniae in a model that simulates in vitro pharmacokinetics in human tonsils. 2002 J. Antimicrob. Chemother. pmid:11751774
Najib NM et al. Bioequivalence assessment of Azomycin (Julphar, UAE) as compared to Zithromax (Pfizer, USA)--two brands of azithromycin--in healthy human volunteers. 2001 Biopharm Drug Dispos pmid:11745903
Aberg JA et al. Presence of macrolide resistance in respiratory flora of HIV-Infected patients receiving either clarithromycin or azithromycin for Mycobacterium avium complex prophylaxis. 2001 Nov-Dec HIV Clin Trials pmid:11742432
Bain DL et al. Chlamydial genovar distribution after community wide antibiotic treatment. 2001 J. Infect. Dis. pmid:11740734
Cascio A et al. Clarithromycin versus azithromycin in the treatment of Mediterranean spotted fever in children: a randomized controlled trial. 2002 Clin. Infect. Dis. pmid:11740701
Butler T Effect of increased inoculum of Salmonella typhi on MIC of azithromycin and resultant growth characteristics. 2001 J. Antimicrob. Chemother. pmid:11733476
Salopek-Rabatić J Chlamydial conjunctivitis in contact lens wearers: successful treatment with single dose azithromycin. 2001 CLAO J pmid:11725983
Intrauterine devices: antibiotic prophylaxis not necessary during insertion. 2001 Prescrire Int pmid:11718174
Gray RH et al. Randomized trial of presumptive sexually transmitted disease therapy during pregnancy in Rakai, Uganda. 2001 Am. J. Obstet. Gynecol. pmid:11717659
Weigl LB et al. [Confluent and reticulate papillomatosis. Successful therapy with azithromycin]. 2001 Hautarzt pmid:11715390
Page RL et al. Possible interaction between intravenous azithromycin and oral cyclosporine. 2001 Pharmacotherapy pmid:11714218
Treadway G and Reisman A Tolerability of 3-day, once-daily azithromycin suspension versus standard treatments for community-acquired paediatric infectious diseases. 2001 Int. J. Antimicrob. Agents pmid:11711256
Hand WL and Hand DL Characteristics and mechanisms of azithromycin accumulation and efflux in human polymorphonuclear leukocytes. 2001 Int. J. Antimicrob. Agents pmid:11711255
Samarendra P et al. QT prolongation associated with azithromycin/amiodarone combination. 2001 Pacing Clin Electrophysiol pmid:11707055
Pukrittayakamee S et al. Therapeutic responses to antibacterial drugs in vivax malaria. 2001 Sep-Oct Trans. R. Soc. Trop. Med. Hyg. pmid:11706666
Postma MJ et al. Cost-effectiveness of partner pharmacotherapy in screening women for asymptomatic infection with Chlamydia Trachomatis. 2001 May-Jun Value Health pmid:11705188
Toro C et al. [Prevalence of primary Helicobacter pylori resistance to eight antimicrobial agents in a hospital in Madrid]. 2001 Rev Esp Quimioter pmid:11704771
Golledge CL and Riley TV The efficacy of an antibiotic protocol for community-acquired pneumonia. 2001 Med. J. Aust. pmid:11700844
Kastner U and Guggenbichler JP Influence of macrolide antibiotics on promotion of resistance in the oral flora of children. 2001 Infection pmid:11688901
Dubois J and St-Pierre C In vitro susceptibility study of BMS-284756 against Legionella species. 2001 Sep-Oct Diagn. Microbiol. Infect. Dis. pmid:11687318
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Contopoulos-Ioannidis DG et al. Meta-analysis of randomized controlled trials on the comparative efficacy and safety of azithromycin against other antibiotics for lower respiratory tract infections. 2001 J. Antimicrob. Chemother. pmid:11679558
Ioannidis JP et al. Meta-analysis of randomized controlled trials on the comparative efficacy and safety of azithromycin against other antibiotics for upper respiratory tract infections. 2001 J. Antimicrob. Chemother. pmid:11679557
Nagai K et al. Activities of a new fluoroketolide, HMR 3787, and its (des)-fluor derivative RU 64399 compared to those of telithromycin, erythromycin A, azithromycin, clarithromycin, and clindamycin against macrolide-susceptible or -resistant Streptococcus pneumoniae and S. pyogenes. 2001 Antimicrob. Agents Chemother. pmid:11600391
Dreses-Werringloer U et al. Effects of azithromycin and rifampin on Chlamydia trachomatis infection in vitro. 2001 Antimicrob. Agents Chemother. pmid:11600348
Chahine C et al. Ultrashort regimen of lansoprazole-amoxicillin-azithromycin for eradicating Helicobacter pylori. 2001 Am J Health Syst Pharm pmid:11596697
Joloba ML et al. Pneumococcal conjugate vaccine serotypes of Streptococcus pneumoniae isolates and the antimicrobial susceptibility of such isolates in children with otitis media. 2001 Clin. Infect. Dis. pmid:11588694
Kent JR et al. Azithromycin: an assessment of its pharmacokinetics and therapeutic potential in CAPD. 2001 Jul-Aug Perit Dial Int pmid:11587400
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Milkovic-Kraus S and Kanceljak-Macan B Occupational airborne allergic contact dermatitis from azithromycin. 2001 Contact Derm. pmid:11553158
Miyazaki S et al. Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice. 2001 J. Antimicrob. Chemother. pmid:11533011
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Schlegel L et al. In vitro activity of midecamycin diacetate, a 16-membered macrolide, against Streptococcus pyogenes isolated in France, 1995-1999. 2001 Clin. Microbiol. Infect. pmid:11531981
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Damianov L et al. [Treatment of genital chlamydia infections with Sumamed]. 2001 Akush Ginekol (Sofiia) pmid:11519320
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Noedl H et al. Antimalarial activity of azithromycin, artemisinin and dihydroartemisinin in fresh isolates of Plasmodium falciparum in Thailand. 2001 Acta Trop. pmid:11495642
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