Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yazdanbakhsh AR et al. | Reduction of non-Betalactam Antibiotics COD by Combined Coagulation and Advanced Oxidation Processes. | 2016 | Water Environ. Res. | pmid:28661328 |
| Liao YS et al. | Azithromycin-Nonsusceptible Shigella flexneri 3a in Men Who Have Sex with Men, Taiwan, 2015-2016. | 2016 | Emerging Infect. Dis. | pmid:28098533 |
| Gawin A et al. | Mildly pruritic palmar rash. | 2016 | J Fam Pract | pmid:28087868 |
| Espadas D et al. | Lack of effect of azithromycin on QT interval in children: a cohort study. | 2016 | Arch. Dis. Child. | pmid:27515186 |
| Zhou Y et al. | Azithromycin therapy during respiratory syncytial virus bronchiolitis: Upper airway microbiome alterations and subsequent recurrent wheeze. | 2016 | J. Allergy Clin. Immunol. | pmid:27339392 |
| Rosenthal PJ | Azithromycin for Malaria? | 2016 | Am. J. Trop. Med. Hyg. | pmid:27215296 |
| Petrelli F et al. | Poly(ADP-ribose) polymerase is not involved in the neuroprotection exerted by azithromycin against ischemic stroke in mice. | 2016 | Eur. J. Pharmacol. | pmid:27663279 |
| Gerhardt P et al. | [Male urethritis]. | 2016 | Ann Dermatol Venereol | pmid:27776813 |
| Dupin N et al. | [Chlamydia trachomatis]. | 2016 | Ann Dermatol Venereol | pmid:27773503 |
| Gong L et al. | Clinical effect of treating secondary asthma attacks of children Mycoplasma pneumoniae with combined therapy of montelukast and azithromycin. | 2016 | Eur Rev Med Pharmacol Sci | pmid:28051240 |
| Alcaraz I et al. | [Mycoplasma genitalium]. | 2016 | Ann Dermatol Venereol | pmid:27773499 |
| Caumes E et al. | [Donovanosis (granuloma inguinale)]. | 2016 | Ann Dermatol Venereol | pmid:27773509 |
| O'Farrell N | Control of gonorrhoea and chlamydia in the UK. | 2016 | Lancet | pmid:27477165 |
| Zhu XH et al. | Viral and Bacterial Etiology of Acute Diarrhea among Children under 5 Years of Age in Wuhan, China. | 2016 | Chin. Med. J. | pmid:27503019 |
| Zhao M et al. | Comparison of minocycline and azithromycin for the treatment of mild scrub typhus in northern China. | 2016 | Int. J. Antimicrob. Agents | pmid:27449540 |
| Dukers-Muijrers NH et al. | Design of the FemCure study: prospective multicentre study on the transmission of genital and extra-genital Chlamydia trachomatis infections in women receiving routine care. | 2016 | BMC Infect. Dis. | pmid:27502928 |
| Huang SW et al. | Azithromycin impairs TLR7 signaling in dendritic cells and improves the severity of imiquimod-induced psoriasis-like skin inflammation in mice. | 2016 | J. Dermatol. Sci. | pmid:27449383 |
| Yoshioka D et al. | Efficacy of β-Lactam-plus-Macrolide Combination Therapy in a Mouse Model of Lethal Pneumococcal Pneumonia. | 2016 | Antimicrob. Agents Chemother. | pmid:27480866 |
| Jacobsson S et al. | WGS analysis and molecular resistance mechanisms of azithromycin-resistant (MIC >2 mg/L) Neisseria gonorrhoeae isolates in Europe from 2009 to 2014. | 2016 | J. Antimicrob. Chemother. | pmid:27432597 |
| Jeong BH et al. | Peak Plasma Concentration of Azithromycin and Treatment Responses in Mycobacterium avium Complex Lung Disease. | 2016 | Antimicrob. Agents Chemother. | pmid:27480854 |
| de Zwart L et al. | Ibrutinib Dosing Strategies Based on Interaction Potential of CYP3A4 Perpetrators Using Physiologically Based Pharmacokinetic Modeling. | 2016 | Clin. Pharmacol. Ther. | pmid:27367453 |
| Abeles SR et al. | Microbial diversity in individuals and their household contacts following typical antibiotic courses. | 2016 | Microbiome | pmid:27473422 |
| Lockington D | Oral azithromycin and blepharitis: symptoms and signs improve, so where are the publications? | 2016 | Clin. Experiment. Ophthalmol. | pmid:27356302 |
| Zhu B et al. | High Resistance to Azithromycin in Clinical Samples from Patients with Sexually Transmitted Diseases in Guangxi Zhuang Autonomous Region, China. | 2016 | PLoS ONE | pmid:27467164 |
| Miyake H et al. | Meibomian Gland Dysfunction Model in Hairless Mice Fed a Special Diet With Limited Lipid Content. | 2016 | Invest. Ophthalmol. Vis. Sci. | pmid:27327582 |
| Kobbernagel HE et al. | Study protocol, rationale and recruitment in a European multi-centre randomized controlled trial to determine the efficacy and safety of azithromycin maintenance therapy for 6Â months in primary ciliary dyskinesia. | 2016 | BMC Pulm Med | pmid:27450411 |
| Sacks HS | In older adults, macrolide antibiotics were not linked to increased risk for ventricular arrhythmia. | 2016 | Ann. Intern. Med. | pmid:27323264 |
| Dunn AL et al. | Naegleria fowleri That Induces Primary Amoebic Meningoencephalitis: Rapid Diagnosis and Rare Case of Survival in a 12-Year-Old Caucasian Girl. | 2016 | Lab Med | pmid:26984830 |
| Yelenich-Huss MJ et al. | Ozena in Immigrants of Differing Backgrounds. | 2016 | Am. J. Trop. Med. Hyg. | pmid:27114295 |
| Saini H et al. | Antimicrobial and antifouling efficacy of urinary catheters impregnated with a combination of macrolide and fluoroquinolone antibiotics against Pseudomonas aeruginosa. | 2016 | Biofouling | pmid:26982572 |
| Vermeersch K et al. | The Belgian trial with azithromycin for acute COPD exacerbations requiring hospitalization: an investigator-initiated study protocol for a multicenter, randomized, double-blind, placebo-controlled trial. | 2016 | Int J Chron Obstruct Pulmon Dis | pmid:27099485 |
| Levy V et al. | A Case of Persistent and Possibly Treatment Resistant Pharyngeal Gonorrhea. | 2016 | Sex Transm Dis | pmid:26967304 |
| Guo Y et al. | Chlamydiaphage φCPG1 Capsid Protein Vp1 Inhibits Chlamydia trachomatis Growth via the Mitogen-Activated Protein Kinase Pathway. | 2016 | Viruses | pmid:27089359 |
| Gülses A and Ayna M | Re: Comparison of Azithromycin and Amoxicillin Before Dental Implant Placement: An Exploratory Study of Bioavailability and Resolution of Postoperative Inflammation. | 2016 | J. Periodontol. | pmid:26962889 |
| Hu J et al. | Streptococcus pneumoniae and Haemophilus influenzae type b carriage in Chinese children aged 12-18 months in Shanghai, China: a cross-sectional study. | 2016 | BMC Infect. Dis. | pmid:27080523 |
| McClure KS and Cameron ST | An audit of expedited treatment for uncomplicated Chlamydia trachomatis index cases at the community pharmacy. | 2016 | Int J STD AIDS | pmid:26945591 |
| Liang JY et al. | Azithromycin-resistant Neisseria gonorrhoeae isolates in Guangzhou, China (2009-2013): coevolution with decreased susceptibilities to ceftriaxone and genetic characteristics. | 2016 | BMC Infect. Dis. | pmid:27080231 |
| McCarthy M | No link between macrolide antibiotics and ventricular arrhythmias, study finds. | 2016 | BMJ | pmid:26905692 |
| Lahra MM and Enriquez RP | Australian Gonococcal Surveillance Programme, 1 July to 30 September 2015. | 2016 | Commun Dis Intell Q Rep | pmid:27080026 |
| Ward E and Duff P | A comparison of 3 antibiotic regimens for prevention of postcesarean endometritis: an historical cohort study. | 2016 | Am. J. Obstet. Gynecol. | pmid:26901276 |
| Slade J et al. | Chlamydial Pre-Infection Protects from Subsequent Herpes Simplex Virus-2 Challenge in a Murine Vaginal Super-Infection Model. | 2016 | PLoS ONE | pmid:26726882 |
| Lococo F et al. | Hemoptysis and Progressive Dyspnea in a 67-Year-Old Woman with History of Renal Transplantation. | 2016 | Am. J. Respir. Crit. Care Med. | pmid:26681504 |
| Mukai S et al. | Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines. | 2016 | Int. J. Oncol. | pmid:26718641 |
| Miyagawa T et al. | Azithromycin recovers reductions in barrier function in human gingival epithelial cells stimulated with tumor necrosis factor-α. | 2016 | Arch. Oral Biol. | pmid:26655749 |
| Smith DJ et al. | Pseudomonas aeruginosa antibiotic resistance in Australian cystic fibrosis centres. | 2016 | Respirology | pmid:26711802 |
| Lübbert C | Antimicrobial therapy of acute diarrhoea: a clinical review. | 2016 | Expert Rev Anti Infect Ther | pmid:26641310 |
| Lee SJ et al. | Maternal azithromycin administration eradicates intra-amniotic Ureaplasma infection: The first human case report. | 2016 | J Obstet Gynaecol | pmid:26634623 |
| Martin I et al. | Decline in Decreased Cephalosporin Susceptibility and Increase in Azithromycin Resistance in Neisseria gonorrhoeae, Canada. | 2016 | Emerging Infect. Dis. | pmid:26689114 |
| Höh H et al. | [MALT Lymphoma of the Conjunctiva in a 13-year old Child--5-Year Relapse-free Follow-up Following Antibiotic Treatment]. | 2016 | Klin Monbl Augenheilkd | pmid:26609671 |
| Yang CJ et al. | Comparison of serological responses to single-dose azithromycin (2 g) versus benzathine penicillin G in the treatment of early syphilis in HIV-infected patients in an area of low prevalence of macrolide-resistant Treponema pallidum infection. | 2016 | J. Antimicrob. Chemother. | pmid:26604241 |
| Luo Q et al. | Surface plasmon resonance sensor for antibiotics detection based on photo-initiated polymerization molecularly imprinted array. | 2016 | Talanta | pmid:27769483 |
| Unger HW et al. | Azithromycin-containing intermittent preventive treatment in pregnancy affects gestational weight gain, an important predictor of birthweight in Papua New Guinea - an exploratory analysis. | 2016 | Matern Child Nutr | pmid:26373537 |
| Zhang Z et al. | Clinical effect of azithromycin as an adjunct to non-surgical treatment of chronic periodontitis: a meta-analysis of randomized controlled clinical trials. | 2016 | J. Periodont. Res. | pmid:26362529 |
| Chang Y et al. | Factors Influencing the HPLC Determination for Related Substances of Azithromycin. | 2016 | J Chromatogr Sci | pmid:26324196 |
| Caspi M et al. | A flow cytometry-based reporter assay identifies macrolide antibiotics as nonsense mutation read-through agents. | 2016 | J. Mol. Med. | pmid:26620677 |
| Brittain C et al. | Gentamicin versus ceftriaxone for the treatment of gonorrhoea (G-TOG trial): study protocol for a randomised trial. | 2016 | Trials | pmid:27881151 |
| Libois A and De Wit S | Which empiric syndromic treatment for urethritis? | 2016 | Int J STD AIDS | pmid:27794143 |
| Gaudreau C et al. | Shigella flexneri with Ciprofloxacin Resistance and Reduced Azithromycin Susceptibility, Canada, 2015. | 2016 | Emerging Infect. Dis. | pmid:27767915 |
| Narita M et al. | Antimicrobial Susceptibility of Microorganisms Isolated from Periapical Periodontitis Lesions. | 2016 | Bull. Tokyo Dent. Coll. | pmid:27665691 |
| Dombrowski JC and Batteiger BE | Reconsidering the Use of Azithromycin for Chlamydial Urethritis. | 2016 | Sex Transm Dis | pmid:27626187 |
| Hazra A | Author Reply. | 2016 Jan-Feb | Indian J Pharmacol | pmid:26997735 |
| Das S and Mohanty M | Comparative evaluation of 2 g single dose versus conventional dose azithromycin in uncomplicated skin and skin structure infections. | 2016 Jan-Feb | Indian J Pharmacol | pmid:26997734 |
| Das A et al. | Azithromycin induced bullous fixed drug eruption. | 2016 Jan-Feb | Indian J Pharmacol | pmid:26997729 |
| Chatterjee S et al. | Azithromycin susceptibility among clinical isolates of Salmonella: Interfacing guidelines with routine practices. | 2016 Jul-Sep | Indian J Med Microbiol | pmid:27514976 |
| Latif SA et al. | Azithromycin buccal patch in treatment of chronic periodontitis. | 2016 Mar-Apr | Indian J Pharmacol | pmid:27127325 |
| Oliveira IS et al. | Evaluation of the improvement of quality of life with Azithromycin in the treatment of eosinophilic nasal polyposis. | 2016 Mar-Apr | Braz J Otorhinolaryngol | pmid:26601998 |
| Akoglu G et al. | Erlotinib-induced purpuric papulopustular eruption treated with pulsed azithromycin. | 2016 May-Jun | Indian J Pharmacol | pmid:27298507 |
| Diniz LM et al. | Bacillary angiomatosis with bone invasion. | 2016 Nov-Dec | An Bras Dermatol | pmid:28099606 |
| Volgers C et al. | Budesonide, fluticasone propionate, and azithromycin do not modulate the membrane vesicle release by THP-1 macrophages and respiratory pathogens during macrophage infection. | 2017 | Inflammopharmacology | pmid:28528362 |
| Mei J et al. | Implications of intrapartum azithromycin on neonatal microbiota. | 2017 | Lancet Infect Dis | pmid:28244378 |
| Stieger N et al. | Solution-mediated crystallization of amorphous azithromycin. | 2017 | Pharmazie | pmid:29441902 |
| Feng X and Liu J | A combination of irsogladine maleate and azithromycin exhibits addictive protective effects in LPS-induced human gingival epithelial cells. | 2017 | Pharmazie | pmid:29441859 |
| Savaris RF et al. | Antibiotic therapy for pelvic inflammatory disease. | 2017 | Cochrane Database Syst Rev | pmid:28436019 |
| Snelling PJ et al. | Rhabdomyolysis Complicating Typhoid Fever in A Child and Review of the Literature. | 2017 | Pediatr. Infect. Dis. J. | pmid:28430751 |
| Koštrun S et al. | Around the macrolide - Impact of 3D structure of macrocycles on lipophilicity and cellular accumulation. | 2017 | Eur J Med Chem | pmid:28410508 |
| Iannetta M et al. | Azithromycin Shows Anti-Zika Virus Activity in Human Glial Cells. | 2017 | Antimicrob. Agents Chemother. | pmid:28839081 |
| Hallström H et al. | Open flap debridement of peri-implantitis with or without adjunctive systemic antibiotics: A randomized clinical trial. | 2017 | J. Clin. Periodontol. | pmid:28836279 |
| Subedi Y | Around Manaslu Ultramarathon: Diarrhea Is Still the King. | 2017 | Wilderness Environ Med | pmid:28735656 |
| Gifford J et al. | Decision support during electronic prescription to stem antibiotic overuse for acute respiratory infections: a long-term, quasi-experimental study. | 2017 | BMC Infect. Dis. | pmid:28760143 |
| Upadhyay K et al. | Combination therapy with ampicillin and azithromycin improved outcomes in a mouse model of group B streptococcal sepsis. | 2017 | PLoS ONE | pmid:28759625 |
| Li R et al. | Effects of oral florfenicol and azithromycin on gut microbiota and adipogenesis in mice. | 2017 | PLoS ONE | pmid:28742883 |
| Bellon H et al. | Interleukin-1α induced release of interleukin-8 by human bronchial epithelial cells in vitro: assessing mechanisms and possible treatment options. | 2017 | Transpl. Int. | pmid:28078769 |
| Li Y et al. | Synergistic Activity of Berberine with Azithromycin against Pseudomonas Aeruginosa Isolated from Patients with Cystic Fibrosis of Lung In Vitro and In Vivo. | 2017 | Cell. Physiol. Biochem. | pmid:28738346 |
| Llop CJ et al. | Antibiotic treatment patterns, costs, and resource utilization among patients with community acquired pneumonia: a US cohort study. | 2017 | Hosp Pract (1995) | pmid:28064542 |
| Pavlova A et al. | Toward the rational design of macrolide antibiotics to combat resistance. | 2017 | Chem Biol Drug Des | pmid:28419786 |
| Yoon HY et al. | Clinical significance of QT-prolonging drug use in patients with MDR-TB or NTM disease. | 2017 | Int. J. Tuberc. Lung Dis. | pmid:28826448 |
| Whiley DM et al. | Molecular Antimicrobial Resistance Surveillance for Neisseria gonorrhoeae, Northern Territory, Australia. | 2017 | Emerging Infect. Dis. | pmid:28820128 |
| Fage C et al. | The combination of oseltamivir with azithromycin does not show additional benefits over oseltamivir monotherapy in mice infected with influenza A(H1N1)pdm2009 virus. | 2017 | J. Med. Virol. | pmid:28792077 |
| Koetsveld J et al. | Susceptibility of the Relapsing-Fever Spirochete Borrelia miyamotoi to Antimicrobial Agents. | 2017 | Antimicrob. Agents Chemother. | pmid:28674060 |
| Agarwal E et al. | Locally Delivered 0.5% Azithromycin as an Adjunct to Non-Surgical Treatment in Patients With Chronic Periodontitis With Type 2 Diabetes: A Randomized Controlled Clinical Trial. | 2017 | J. Periodontol. | pmid:22655911 |
| Bouklouze A et al. | Azithromycin assay in drug formulations: Validation of a HPTLC method with a quadratic polynomial calibration model using the accuracy profile approach. | 2017 | Ann Pharm Fr | pmid:27692351 |
| Collins SA et al. | Cephalosporin-3'-Diazeniumdiolate NO Donor Prodrug PYRRO-C3D Enhances Azithromycin Susceptibility of Nontypeable Haemophilus influenzae Biofilms. | 2017 | Antimicrob. Agents Chemother. | pmid:27919896 |
| Han B et al. | Intrahepatic cholestasis of pregnancy or azithromycin-induced intrahepatic cholestasis: A case report. | 2017 | Medicine (Baltimore) | pmid:29384912 |
| Allen GP and Harris KA | Resistance Selection in Shigella flexneri by Azithromycin, Ceftriaxone, Ciprofloxacin, Levofloxacin, and Moxifloxacin. | 2017 | Antimicrob. Agents Chemother. | pmid:28483960 |
| Waetzig V et al. | Neurodegenerative effects of azithromycin in differentiated PC12 cells. | 2017 | Eur. J. Pharmacol. | pmid:28479141 |
| Park HS et al. | Subantibiotic dose of azithromycin attenuates alveolar bone destruction and improves trabecular microarchitectures in a rat model of experimental periodontitis: A study using micro-computed tomography. | 2017 | Int. Immunopharmacol. | pmid:28432937 |
| Horner P and Saunders J | Should azithromycin 1 g be abandoned as a treatment for bacterial STIs? The case for and against. | 2017 | Sex Transm Infect | pmid:27418572 |
| Quinn KL et al. | Macrolides, Digoxin Toxicity and the Risk of Sudden Death: A Population-Based Study. | 2017 | Drug Saf | pmid:28421551 |
| Bergeron A et al. | Azithromycin and Survival After Hematopoietic Stem Cell Transplant-Reply. | 2017 | JAMA | pmid:29279924 |
| Fuji S | Azithromycin and Survival After Hematopoietic Stem Cell Transplant. | 2017 | JAMA | pmid:29279920 |