Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Cheng B | Advances in prevention and treatment of MAC. | 1995 | PI Perspect | pmid:11363104 |
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| Leophonte P | [Azithromycin and bronchopulmonary infections]. | 1995 | Pathol. Biol. | pmid:8539078 |
| Scheen AJ | [Pharma-clinics. Drug of the month. Azithromycin (Zitromax)]. | 1995 | Rev Med Liege | pmid:7481274 |
| Nuovo J et al. | Cost-effectiveness analysis of five different antibiotic regimens for the treatment of uncomplicated Chlamydia trachomatis cervicitis. | 1995 Jan-Feb | J Am Board Fam Pract | pmid:7701965 |
| Rifabutin for MAC questioned. | 1995 Jul-Aug | Posit Aware | pmid:11362571 | |
| Amin NM and Breadon G | An open-label, noncomparative study to evaluate the efficacy, safety, and tolerability of azithromycin in the treatment of patients with acute sinusitis. | 1995 Jul-Aug | Clin Ther | pmid:8565033 |
| Qadri SM et al. | Antibacterial activity of azithromycin against Brucella melitensis. | 1995 Jul-Aug | Chemotherapy | pmid:7555205 |
| What's in the water? | 1995 Mar-Apr | Treat Rev | pmid:11362299 | |
| Hashisaki GT | Update on macrolide antibiotics. | 1995 May-Jun | Am J Otolaryngol | pmid:7661309 |
| Sternon J et al. | Azithromycin compared with clarithromycin in the treatment of adult patients with acute purulent tracheobronchitis: a cost of illness study. | 1995 Nov-Dec | J. Int. Med. Res. | pmid:8746608 |
| Höffler D et al. | Pharmacokinetics of azithromycin in normal and impaired renal function. | 1995 Nov-Dec | Infection | pmid:8655206 |
| Bauernfeind A et al. | Comparative pharmacodynamics of clarithromycin and azithromycin against respiratory pathogens. | 1995 Sep-Oct | Infection | pmid:8557398 |
| Erdogru T et al. | The treatment of non-gonococcal urethritis with single dose oral azithromycin. | 1995 Sep-Oct | J. Int. Med. Res. | pmid:8529783 |
| Haddix AC et al. | The cost effectiveness of azithromycin for Chlamydia trachomatis infections in women. | 1995 Sep-Oct | Sex Transm Dis | pmid:7502180 |
| Berg-Candolfi M and Candolfi E | Depression of the N-demethylation of erythromycin, azithromycin, clarithromycin and clindamycin in murine Toxoplasma infection. | 1996 | Int. J. Parasitol. | pmid:9024879 |
| Montenez JP et al. | Interaction of the macrolide azithromycin with phospholipids. II. Biophysical and computer-aided conformational studies. | 1996 | Eur. J. Pharmacol. | pmid:8957239 |
| Currier J | Progress report: prophylaxis and therapy for MAC. | 1996 | AIDS Clin Care | pmid:11363599 |
| Kuzman I et al. | Azithromycin in the treatment of pneumonias caused by Chlamydia spp: a retrospective study. | 1996 | Int J Clin Pharmacol Res | pmid:9172008 |
| Old drug approved for MAC prevention. | 1996 | AIDS Alert | pmid:11363659 | |
| Torres G | MAC prophylaxis revisited. | 1996 | GMHC Treat Issues | pmid:11363706 |
| Antivirals key to MAC prevention regimen. | 1996 | AIDS Alert | pmid:11363722 | |
| Marco M | Opportunistic infections in Vancouver. | 1996 | GMHC Treat Issues | pmid:11363841 |
| Azithromycin effective in preventing MAC. | 1996 | AIDS Alert | pmid:11363857 | |
| Segreti J et al. | In vitro activity of macrolides against intracellular Legionella pneumophila. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8902407 |
| ZaÄtseva EA et al. | [Comparative study of the antimicrobial activity of pefloxacin, ciprofloxacin, norfloxacin and azithromycin with respect to Strains of Yersinia pseudotuberculosis]. | 1996 | Antibiot. Khimioter. | pmid:8762820 |
| Lode H et al. | Azithromycin--review of key chemical, pharmacokinetic and microbiological features. | 1996 | J. Antimicrob. Chemother. | pmid:8818841 |
| Girard AE et al. | Correlation of increased azithromycin concentrations with phagocyte infiltration into sites of localized infection. | 1996 | J. Antimicrob. Chemother. | pmid:8818842 |
| Girard D et al. | Influence of immunosuppression on the pharmacokinetics and pharmacodynamics of azithromycin in infected mouse tissues. | 1996 | J. Antimicrob. Chemother. | pmid:8818843 |
| Foulds G et al. | The absence of an effect of food on the bioavailability of azithromycin administered as tablets, sachet or suspension. | 1996 | J. Antimicrob. Chemother. | pmid:8818844 |
| Wintermeyer SM et al. | Dirithromycin: a new macrolide. | 1996 | Ann Pharmacother | pmid:8893122 |
| Young LS | Azithromycin in the management of opportunistic infections. | 1996 | Int J STD AIDS | pmid:8652721 |
| Chang HR | The potential role of azithromycin in the treatment of prophylaxis of toxoplasmosis. | 1996 | Int J STD AIDS | pmid:8652722 |
| Waugh MA | Azithromycin in gonorrhoea. | 1996 | Int J STD AIDS | pmid:8652723 |
| Young LS | Treatment and prophylaxis of Mycobacterium avium complex. | 1996 | Int J STD AIDS | pmid:8652724 |
| Hoepelman IM | Human cryptosporidiosis. | 1996 | Int J STD AIDS | pmid:8652725 |
| McCutchan JA | Azithromycin in the prophylaxis of opportunistic infections in AIDS. | 1996 | Int J STD AIDS | pmid:8652726 |
| Ishida Y et al. | [Pharmacokinetic and clinical evaluation of azithromycin in pediatric infections]. | 1996 | Jpn J Antibiot | pmid:8988415 |
| Ohtsuka Y et al. | [Pharmacokinetic and clinical studies on azithromycin in children]. | 1996 | Jpn J Antibiot | pmid:8988416 |
| Cammarota G et al. | Helicobacter pylori eradication using one-week low-dose lansoprazole plus amoxycillin and either clarithromycin or azithromycin. | 1996 | Aliment. Pharmacol. Ther. | pmid:8971300 |
| Pilotto A et al. | Cure of Helicobacter pylori infection in the elderly: effects of eradication on gastritis and serological markers. | 1996 | Aliment. Pharmacol. Ther. | pmid:8971305 |
| Andenaes K et al. | Preoperative bacterial colonization and its influence on postoperative wound infections in plastic surgery. | 1996 | J. Hosp. Infect. | pmid:8971618 |
| Pozniak A and Nelson MR | Against the proposition: all patients with advanced HIV disease should be offered rifabutin prophylaxis. | 1996 | Genitourin Med | pmid:8976832 |
| Kuznetsova SM | ["Sumamed in the treatment of urogenital infections"]. | 1996 | Antibiot. Khimioter. | pmid:8929115 |
| Skripkin IuK et al. | [The problem of diagnosis and treatment of urogenital chlamydiosis in Russia]. | 1996 | Antibiot. Khimioter. | pmid:8929120 |
| Vasil'ev MM and Gazarian IIu | [Clinico-laboratory evaluation of the effectiveness of azithromycin in the treatment of patients with Chlamydia and mixed Chlamydia-gonorrhea infections]. | 1996 | Antibiot. Khimioter. | pmid:8929122 |
| Schaad UB and Heynen G | Evaluation of the efficacy, safety and toleration of azithromycin vs. penicillin V in the treatment of acute streptococcal pharyngitis in children: results of a multicenter, open comparative study. The Swiss Tonsillopharyngitis Study Group. | 1996 | Pediatr. Infect. Dis. J. | pmid:8878223 |
| McLinn S and Williams D | Incidence of antibiotic-resistant Streptococcus pneumoniae and beta-lactamase-positive Haemophilus influenzae in clinical isolates from patients with otitis media. | 1996 | Pediatr. Infect. Dis. J. | pmid:8878239 |
| McCarty J | A multicenter, open label trial of azithromycin for the treatment of children with acute otitis media. | 1996 | Pediatr. Infect. Dis. J. | pmid:8878240 |
| Cellesi C et al. | Susceptibility of macrolide and beta-lactam antibiotics of Streptococcus pyogenes strains isolated over a four-year period in central Italy. | 1996 | J Chemother | pmid:8808714 |