Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Sexually Transmitted Diseases, Bacterial D015231 5 associated lipids
Fever of Unknown Origin D005335 3 associated lipids
Conjunctivitis, Bacterial D003234 3 associated lipids
Psittacosis D009956 4 associated lipids
Conjunctivitis, Inclusion D003235 4 associated lipids
Typhus, Endemic Flea-Borne D014437 3 associated lipids
Urethral Diseases D014522 4 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Lymphogranuloma Venereum D008219 4 associated lipids
Superinfection D015163 3 associated lipids
Otitis Media, Suppurative D010035 4 associated lipids
Serum Sickness D012713 7 associated lipids
Bites, Human D001734 2 associated lipids
Rickettsia Infections D012282 5 associated lipids
Pharyngeal Diseases D010608 4 associated lipids
Granuloma Inguinale D006100 2 associated lipids
Erythema Chronicum Migrans D015787 3 associated lipids
Elephantiasis, Filarial D004605 4 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Bartonella Infections D001474 3 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
Otorhinolaryngologic Diseases D010038 3 associated lipids
Dry Socket D004368 3 associated lipids
Nasopharyngeal Diseases D009302 2 associated lipids
Furunculosis D005667 2 associated lipids
Elephantiasis D004604 2 associated lipids
Lymphangitis D008205 4 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Herpes Genitalis D006558 2 associated lipids
Pericoronitis D010497 2 associated lipids
Tuberculosis, Urogenital D014401 2 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Abdominal Abscess D018784 2 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Hoarseness D006685 2 associated lipids
Scrub Typhus D012612 3 associated lipids
Tuberculosis, Avian D014379 2 associated lipids
Pneumocystis Infections D016720 1 associated lipids
Frontal Sinusitis D015522 1 associated lipids
Toxoplasmosis, Ocular D014126 2 associated lipids
Typhoid Fever D014435 2 associated lipids
Acquired Hyperostosis Syndrome D020083 1 associated lipids
Central Nervous System Protozoal Infections D020808 3 associated lipids
Syncope, Vasovagal D019462 1 associated lipids
Leishmaniasis, Mucocutaneous D007897 1 associated lipids
Trichiasis D058457 1 associated lipids
Paratyphoid Fever D010284 1 associated lipids
Ectodermal Dysplasia D004476 1 associated lipids
Tooth Erosion D014077 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Thompson C et al. A family cluster of Chlamydia trachomatis infection. 2001 BMJ pmid:11408308
Jacobson GF et al. A randomized controlled trial comparing amoxicillin and azithromycin for the treatment of Chlamydia trachomatis in pregnancy. 2001 Am. J. Obstet. Gynecol. pmid:11408852
Matsunaga T [Pharmacological and pharmacokinetic properties of azithromycin (Zithromac), a novel 15-membered ring macrolide antibacterial agent]. 2001 Nippon Yakurigaku Zasshi pmid:11411344
Krudsood S et al. A randomized clinical trial of combinations of artesunate and azithromycin for treatment of uncomplicated Plasmodium falciparum malaria in Thailand. 2000 Southeast Asian J. Trop. Med. Public Health pmid:11414432
Kain KC et al. Malaria chemoprophylaxis in the age of drug resistance. I. Currently recommended drug regimens. 2001 Clin. Infect. Dis. pmid:11418883
Chetchotisakd P et al. Maintenance therapy of melioidosis with ciprofloxacin plus azithromycin compared with cotrimoxazole plus doxycycline. 2001 Jan-Feb Am. J. Trop. Med. Hyg. pmid:11425157
Tabbara KF Trachoma: a review. 2001 J Chemother pmid:11434524
Lisby G et al. Bacteremia and meningitis caused by a macrolide-sensitive strain of Streptococcus pneumoniae during treatment with azithromycin. 2001 Clin. Infect. Dis. pmid:11438918
Ishimatsu Y et al. [Effect of macrolide antibiotics on apoptosis induction]. 2001 Jpn J Antibiot pmid:11439895
Edelstein PH et al. In vitro activity of gemifloxacin (SB-265805, LB20304a) against Legionella pneumophila and its pharmacokinetics in guinea pigs with L. pneumophila pneumonia. 2001 Antimicrob. Agents Chemother. pmid:11451675
Arellano-Rodrigo E et al. [Torsade de pointes and cardiorespiratory arrest induced by azithromycin in a patient with congenital long QT syndrome]. 2001 Med Clin (Barc) pmid:11459586
Fraser-Hurt N et al. Efficacy of oral azithromycin versus topical tetracycline in mass treatment of endemic trachoma. 2001 Bull. World Health Organ. pmid:11477966
Gray GC and Ryan MA Azithromycin chemoprophylaxis. 2001 J. Infect. Dis. pmid:11494171
Noedl H et al. Antimalarial activity of azithromycin, artemisinin and dihydroartemisinin in fresh isolates of Plasmodium falciparum in Thailand. 2001 Acta Trop. pmid:11495642
Gómez J et al. [Prospective, comparative study (1994-1998) of the influence of short-term prophylactic treatment with azithromycin on patients with advanced COPD]. 2000 Rev Esp Quimioter pmid:11498704
Tyteca D et al. Azithromycin, a lysosomotropic antibiotic, impairs fluid-phase pinocytosis in cultured fibroblasts. 2001 Eur. J. Cell Biol. pmid:11499789
Dillon JA et al. Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from three Caribbean countries: Trinidad, Guyana, and St. Vincent. 2001 Sex Transm Dis pmid:11518867
Dillon JA et al. Reduced susceptibility to azithromycin and high percentages of penicillin and tetracycline resistance in Neisseria gonorrhoeae isolates from Manaus, Brazil, 1998. 2001 Sex Transm Dis pmid:11518869
Damianov L et al. [Treatment of genital chlamydia infections with Sumamed]. 2001 Akush Ginekol (Sofiia) pmid:11519320
González de Aledo Linos A and García Merino J [Control of a school outbreak of serogroup B meningococcal disease by chemoprophylaxis with azithromycin and ciprofloxacin]. 2000 An. Esp. Pediatr. pmid:11521657