Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Salimi A et al. | Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect. | 2016 | Xenobiotica | pmid:26068526 |
| Gupta A and Khanna S | Repeat Clostridium difficile Testing. | 2016 | JAMA | pmid:27959982 |
| Misra R and Prasad KN | Antimicrobial susceptibility to azithromycin among Salmonella enterica Typhi and Paratyphi A isolates from India. | 2016 | J. Med. Microbiol. | pmid:27902389 |
| Martande SS et al. | Clinical and microbiological effects of systemic azithromycin in adjunct to nonsurgical periodontal therapy in treatment of Aggregatibacter actinomycetemcomitans associated periodontitis: a randomized placebo-controlled clinical trial. | 2016 | J Investig Clin Dent | pmid:25044531 |
| Hanssens L et al. | The clinical benefits of long-term supplementation with omega-3 fatty acids in cystic fibrosis patients - A pilot study. | 2016 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:27154364 |
| van den Berg GF et al. | Chlamydia screening and prophylactic treatment in termination of pregnancy clinics in the Netherlands and Great Britain: a qualitative study. | 2016 | Eur J Contracept Reprod Health Care | pmid:27701927 |
| Hirasawa K et al. | Macrolide Antibiotics Exhibit Cytotoxic Effect under Amino Acid-Depleted Culture Condition by Blocking Autophagy Flux in Head and Neck Squamous Cell Carcinoma Cell Lines. | 2016 | PLoS ONE | pmid:27977675 |
| EmiralioÄŸlu N et al. | Long term azithromycin therapy in patients with cystic fibrosis. | 2016 | Turk. J. Pediatr. | pmid:27922234 |
| Mougari F et al. | Infections caused by Mycobacterium abscessus: epidemiology, diagnostic tools and treatment. | 2016 | Expert Rev Anti Infect Ther | pmid:27690688 |
| Johnston SL et al. | Azithromycin for Acute Exacerbations of Asthma : The AZALEA Randomized Clinical Trial. | 2016 | JAMA Intern Med | pmid:27653939 |
| Zhao X et al. | Sensitive and Simplified Detection of Antibiotic Influence on the Dynamic and Versatile Changes of Fecal Short-Chain Fatty Acids. | 2016 | PLoS ONE | pmid:27907030 |
| Mosquera RA et al. | Anti-inflammatory effect of prophylactic macrolides on children with chronic lung disease: a protocol for a double-blinded randomised controlled trial. | 2016 | BMJ Open | pmid:27638496 |
| Kissinger PJ et al. | Azithromycin Treatment Failure for Chlamydia trachomatis Among Heterosexual Men With Nongonococcal Urethritis. | 2016 | Sex Transm Dis | pmid:27631353 |
| Nielsen HL et al. | Azithromycin vs. Placebo for the Clinical Outcome in Campylobacter concisus Diarrhoea in Adults: A Randomized, Double-Blinded, Placebo-Controlled Clinical Trial. | 2016 | PLoS ONE | pmid:27893820 |
| Tepper M et al. | Mass Treatment with Single-Dose Azithromycin for Yaws. | 2016 | N. Engl. J. Med. | pmid:27626527 |
| Phiri K et al. | Parasitological Clearance Rates and Drug Concentrations of a Fixed Dose Combination of Azithromycin-Chloroquine in Asymptomatic Pregnant Women with Plasmodium Falciparum Parasitemia: An Open-Label, Non-Comparative Study in Sub-Saharan Africa. | 2016 | PLoS ONE | pmid:27861509 |
| Eckhoff G et al. | Mass Treatment with Single-Dose Azithromycin for Yaws. | 2016 | N. Engl. J. Med. | pmid:27626526 |
| Peart JM et al. | Sporotrichoid fluctuant nodules. | 2016 | Cutis | pmid:27622258 |
| Elshafie BE et al. | The Epidemiology of Trachoma in Darfur States and Khartoum State, Sudan: Results of 32 Population-Based Prevalence Surveys. | 2016 | Ophthalmic Epidemiol | pmid:27841721 |
| Sadatsafavi M et al. | The Association Between Rate and Severity of Exacerbations in Chronic Obstructive Pulmonary Disease: An Application of a Joint Frailty-Logistic Model. | 2016 | Am. J. Epidemiol. | pmid:27737842 |
| Nair S et al. | WGS for surveillance of antimicrobial resistance: a pilot study to detect the prevalence and mechanism of resistance to azithromycin in a UK population of non-typhoidal Salmonella. | 2016 | J. Antimicrob. Chemother. | pmid:27585964 |
| Mwingira UJ et al. | Progress of Trachoma Mapping in Mainland Tanzania: Results of Baseline Surveys from 2012 to 2014. | 2016 | Ophthalmic Epidemiol | pmid:27775455 |
| Wind CM et al. | Time to clearance of Chlamydia trachomatis RNA and DNA after treatment in patients coinfected with Neisseria gonorrhoeae - a prospective cohort study. | 2016 | BMC Infect. Dis. | pmid:27724878 |
| Yasuda M et al. | Remarkable increase of Neisseria gonorrhoeae with decreased susceptibility of azithromycin and increase in the failure of azithromycin therapy in male gonococcal urethritis in Sendai in 2015. | 2016 | J. Infect. Chemother. | pmid:27578029 |
| Davido B et al. | Why should 1 gram of ceftriaxone monotherapy be considered as a therapeutic option in gonococcal sexually transmitted diseases? | 2016 | Clin. Microbiol. Infect. | pmid:27404364 |
| Belkacem A et al. | Molecular epidemiology and mechanisms of resistance of azithromycin-resistant Neisseria gonorrhoeae isolated in France during 2013-14. | 2016 | J. Antimicrob. Chemother. | pmid:27301565 |
| Malhotra S et al. | Prevalence of Trachoma in Car-Nicobar Island, India after Three Annual Rounds of Mass Drug Administration with Azithromycin. | 2016 | PLoS ONE | pmid:27391274 |
| Marks M | Yaws: towards the WHO eradication target. | 2016 | Trans. R. Soc. Trop. Med. Hyg. | pmid:27268712 |
| Liu B et al. | Relationship between Community Drug Administration Strategy and Changes in Trachoma Prevalence, 2007 to 2013. | 2016 | PLoS Negl Trop Dis | pmid:27385309 |
| Long SS | Optimizing antimicrobial therapy in children. | 2016 | J. Infect. | pmid:27263076 |
| Katanami Y et al. | Six Cases of Paratyphoid Fever Due to Salmonella Paratyphi A in Travelers Returning from Myanmar Between July 2014 and August 2015. | 2016 | Am. J. Trop. Med. Hyg. | pmid:27352874 |
| Mertens TC et al. | Azithromycin differentially affects the IL-13-induced expression profile in human bronchial epithelial cells. | 2016 | Pulm Pharmacol Ther | pmid:27246785 |
| Wang X et al. | Increased therapeutic efficacy of combination of azithromycin and ceftazidime on Pseudomonas aeruginosa biofilm in an animal model of ureteral stent infection. | 2016 | BMC Microbiol. | pmid:27341798 |
| Das S et al. | Revisit of fluoroquinolone and azithromycin susceptibility breakpoints for Salmonella enterica serovar Typhi. | 2016 | J. Med. Microbiol. | pmid:27221661 |
| Fifer H et al. | Failure of Dual Antimicrobial Therapy in Treatment of Gonorrhea. | 2016 | N. Engl. J. Med. | pmid:27332921 |
| Bacharier LB et al. | Early Azithromycin Treatment to Prevent Severe Lower Respiratory Tract Illnesses in Children--Reply. | 2016 | JAMA | pmid:27187309 |
| Gesink D et al. | Mycoplasma genitalium in Toronto, Ont: Estimates of prevalence and macrolide resistance. | 2016 | Can Fam Physician | pmid:27331225 |
| Fleming-Dutra KE et al. | Early Azithromycin Treatment to Prevent Severe Lower Respiratory Tract Illnesses in Children. | 2016 | JAMA | pmid:27187308 |
| Kimani J et al. | Efficacy and Safety of Azithromycin-Chloroquine versus Sulfadoxine-Pyrimethamine for Intermittent Preventive Treatment of Plasmodium falciparum Malaria Infection in Pregnant Women in Africa: An Open-Label, Randomized Trial. | 2016 | PLoS ONE | pmid:27326859 |
| Morgan R et al. | Unusual cause of lymphangitis in a 2-year-old boy. | 2016 | BMJ Case Rep | pmid:27181743 |
| Weckmann M et al. | Treatment with rhDNase in patients with cystic fibrosis alters in-vitro CHIT-1 activity of isolated leucocytes. | 2016 | Clin. Exp. Immunol. | pmid:27324468 |
| Kong FY et al. | Higher organism load associated with failure of azithromycin to treat rectal chlamydia. | 2016 | Epidemiol. Infect. | pmid:27180823 |
| Oliveira GN et al. | Congenital dacryocystocoele with prenatal diagnosis. | 2016 | BMJ Case Rep | pmid:27166005 |
| Falay D et al. | Microbiological, clinical and molecular findings of non-typhoidal Salmonella bloodstream infections associated with malaria, Oriental Province, Democratic Republic of the Congo. | 2016 | BMC Infect. Dis. | pmid:27286886 |
| Horner PJ et al. | 2016 European guideline on the management of non-gonococcal urethritis. | 2016 | Int J STD AIDS | pmid:27147267 |
| El-Shitany NA and El-Desoky K | Protective Effects of Carvedilol and Vitamin C against Azithromycin-Induced Cardiotoxicity in Rats via Decreasing ROS, IL1-β, and TNF-α Production and Inhibiting NF-κB and Caspase-3 Expression. | 2016 | Oxid Med Cell Longev | pmid:27274777 |
| Kreuter A and Wieland U | Azithromycin versus Doxycycline for Chlamydia. | 2016 | N. Engl. J. Med. | pmid:27144858 |
| GarcÃa-Quintanilla M et al. | Inhibition of LpxC Increases Antibiotic Susceptibility in Acinetobacter baumannii. | 2016 | Antimicrob. Agents Chemother. | pmid:27270288 |
| Schachter J | Azithromycin versus Doxycycline for Chlamydia. | 2016 | N. Engl. J. Med. | pmid:27144857 |
| Yuan Z et al. | Randomized controlled clinical trial on the efficacy of fosfomycin trometamol for uncomplicated gonococcal urethritis in men. | 2016 | Clin. Microbiol. Infect. | pmid:27064136 |
| Farrell DJ et al. | Results from the Solithromycin International Surveillance Program (2014). | 2016 | Antimicrob. Agents Chemother. | pmid:27044551 |
| Moore BR et al. | Safety, tolerability and pharmacokinetic properties of coadministered azithromycin and piperaquine in pregnant Papua New Guinean women. | 2016 | Br J Clin Pharmacol | pmid:26889763 |
| Mathew JL et al. | Oral Azithromycin for Acute Episodic Airway Symptoms in Young Children: Evidence-based Medicine Viewpoint. | 2016 | Indian Pediatr | pmid:27029689 |
| Pavlović D and Mutak S | Synthesis and antibacterial evaluation of novel 4″-glycyl linked quinolyl-azithromycins with potent activity against macrolide-resistant pathogens. | 2016 | Bioorg. Med. Chem. | pmid:26860929 |
| Roca A et al. | Oral azithromycin given during labour decreases bacterial carriage in the mothers and their offspring: a double-blind randomized trial. | 2016 | Clin. Microbiol. Infect. | pmid:27026482 |
| Oey M and Malhotra P | Azithromycin and ceftriaxone combination treatment for relapsed Salmonella Paratyphi A bacteraemia. | 2016 | J Travel Med | pmid:26858276 |
| DeCoster B et al. | Expedited Partner Therapy: Clinical Considerations and Public Health Explorations. | 2016 | AMA J Ethics | pmid:27002992 |
| Zhou T et al. | Determination of azithromycin residue in pork using a molecularly imprinted monolithic microcolumn coupled to liquid chromatography with tandem mass spectrometry. | 2016 | J Sep Sci | pmid:26854282 |
| Das MC et al. | Attenuation of Pseudomonas aeruginosa biofilm formation by Vitexin: A combinatorial study with azithromycin and gentamicin. | 2016 | Sci Rep | pmid:27000525 |
| Saleh A et al. | Comparison of adjunctive azithromycin and amoxicillin/metronidazole for patients with chronic periodontitis: preliminary randomized control trial. | 2016 | Aust Dent J | pmid:26836781 |
| Maeda M et al. | Study on rectal administration of azithromycin by suppository for pediatric use. | 2016 | Int J Clin Pharmacol Ther | pmid:26833461 |
| Jost C et al. | Susceptibility of enterohaemorrhagic Escherichia coli to azithromycin in France and analysis of resistance mechanisms. | 2016 | J. Antimicrob. Chemother. | pmid:26832755 |
| Demczuk W et al. | Genomic Epidemiology and Molecular Resistance Mechanisms of Azithromycin-Resistant Neisseria gonorrhoeae in Canada from 1997 to 2014. | 2016 | J. Clin. Microbiol. | pmid:26935729 |
| Mohotti JE et al. | A case of bilateral endogenous bacterial endophthalmitis from Streptococcus pneumoniae bacteraemia. | 2016 | Med. J. Aust. | pmid:26821111 |
| Trac MH et al. | Macrolide antibiotics and the risk of ventricular arrhythmia in older adults. | 2016 | CMAJ | pmid:26903359 |
| Marks M et al. | Mass drug administration of azithromycin for trachoma reduces the prevalence of genital Chlamydia trachomatis infection in the Solomon Islands. | 2016 | Sex Transm Infect | pmid:26888658 |
| Economopoulos KP et al. | Prevention of antibiotic-associated metabolic syndrome in mice by intestinal alkaline phosphatase. | 2016 | Diabetes Obes Metab | pmid:26876427 |
| Kang JY et al. | Long-term azithromycin ameliorates not only airway inflammation but also remodeling in a murine model of chronic asthma. | 2016 | Pulm Pharmacol Ther | pmid:26778828 |
| Sridhar S et al. | High recurrence rate supports need for secondary prophylaxis in non-HIV patients with disseminated mycobacterium avium complex infection: a multi-center observational study. | 2016 | BMC Infect. Dis. | pmid:26861696 |
| Peters RP et al. | Gonococcal Conjunctivitis Despite Successful Treatment of Male Urethritis Syndrome. | 2016 | Sex Transm Dis | pmid:26760182 |
| Topp E et al. | Reduced persistence of the macrolide antibiotics erythromycin, clarithromycin and azithromycin in agricultural soil following several years of exposure in the field. | 2016 | Sci. Total Environ. | pmid:27096634 |
| Li X et al. | Macrolides use and the risk of sudden cardiac death. | 2016 | Expert Rev Anti Infect Ther | pmid:27086751 |
| Hood D et al. | A new model for non-typeable Haemophilus influenzae middle ear infection in the Junbo mutant mouse. | 2016 | Dis Model Mech | pmid:26611891 |
| Liu H et al. | [A systematic review of the therapy for Mycoplasma pneumoniae infections in children]. | 2016 | Zhonghua Er Ke Za Zhi | pmid:26875461 |
| Arnold FW et al. | Macrolide Use and Neutrophil Function/Cytokine Levels in Hospitalized Patients with Community-Acquired Pneumonia: A Pilot Study. | 2016 | Lung | pmid:26553025 |
| Olszewska-Sosińska O et al. | Persistence of non-typeable Haemophilus Influenzae in the pharynx of children with adenotonsillar hypertrophy after treatment with azithromycin. | 2016 | Pathog Dis | pmid:26546328 |
| Wakiguchi H et al. | Multiple Renal and Splenic Lesions in Cat Scratch Disease. | 2016 | Jpn. J. Infect. Dis. | pmid:26567841 |
| So W et al. | Poor outcomes of empiric ceftriaxone ± azithromycin for community-acquired pneumonia caused by methicillin-susceptible Staphylococcus aureus. | 2016 | Intern Emerg Med | pmid:26531307 |
| Amantea D et al. | Azithromycin protects mice against ischemic stroke injury by promoting macrophage transition towards M2 phenotype. | 2016 | Exp. Neurol. | pmid:26518285 |
| Manavi K et al. | Comparison of doxycycline with azithromycin in treatment of pharyngeal chlamydia infection. | 2016 | Int J STD AIDS | pmid:26511655 |
| Williams KM et al. | Fluticasone, Azithromycin, and Montelukast Treatment for New-Onset Bronchiolitis Obliterans Syndrome after Hematopoietic Cell Transplantation. | 2016 | Biol. Blood Marrow Transplant. | pmid:26475726 |
| Nicholson TT et al. | Assessing potential risks of treatment with long-term azithromycin in COPD patients: long-term oxygen users beware? | 2016 | Ir J Med Sci | pmid:26502012 |
| Deguchi T et al. | Multidrug-Resistant Mycoplasma genitalium Is Increasing. | 2016 | Clin. Infect. Dis. | pmid:26494825 |
| Kong FY et al. | Reply to Deguchi et al. | 2016 | Clin. Infect. Dis. | pmid:26494824 |
| VÃchová B et al. | First molecular identification of Babesia gibsoni in dogs from Slovakia, central Europe. | 2016 | Ticks Tick Borne Dis | pmid:26304014 |
| Bhargava A et al. | Scrub typhus in Uttarakhand & adjoining Uttar Pradesh: Seasonality, clinical presentations & predictors of mortality. | 2016 | Indian J. Med. Res. | pmid:28474627 |
| Fegan D et al. | Tropical leg ulcers in children: more than yaws. | 2016 | Trop Doct | pmid:26289420 |
| Kasten G et al. | Development of low density azithromycin-loaded polycaprolactone microparticles for pulmonary delivery. | 2016 | Drug Dev Ind Pharm | pmid:26289002 |
| Lee RA et al. | Evaluation of baseline corrected QT interval and azithromycin prescriptions in an academic medical center. | 2016 | J Hosp Med | pmid:26287278 |
| Kasten G et al. | Development of low density azithromycin-loaded polycaprolactone microparticles for pulmonary delivery. | 2016 | Drug Dev Ind Pharm | pmid:26266961 |
| Osborne LG et al. | Enteric fever in a British soldier from Sierra Leone. | 2016 | J R Army Med Corps | pmid:26243802 |
| Lemieux JE et al. | A global map of genetic diversity in Babesia microti reveals strong population structure and identifies variants associated with clinical relapse. | 2016 | Nat Microbiol | pmid:27572973 |
| Narayanasamy DK et al. | Clinico - Laboratory Profile of Scrub Typhus - An Emerging Rickettsiosis in India. | 2016 | Indian J Pediatr | pmid:27352842 |
| Keenan JD et al. | Nasopharyngeal Pneumococcal Serotypes Before and After Mass Azithromycin Distributions for Trachoma. | 2016 | J Pediatric Infect Dis Soc | pmid:27199475 |
| Tous Romero F et al. | Acute Infection by Staphylococcus simulans in the Hand of a Man. | 2016 | JAMA Dermatol | pmid:27144675 |
| Horner P et al. | 2015 UK National Guideline on the management of non-gonococcal urethritis. | 2016 | Int J STD AIDS | pmid:26002319 |
| Ni C et al. | High prevalence of Neisseria gonorrhoeae with high-level resistance to azithromycin in Hangzhou, China. | 2016 | J. Antimicrob. Chemother. | pmid:27090631 |
| Garnier C et al. | Intra-nodal injection of gentamicin for the treatment of suppurated cat scratch disease's lymphadenitis. | 2016 | Infection | pmid:26001741 |
| Wright H et al. | Evaluating Guideline-Recommended Antibiotic Practices for Childhood Respiratory Infections: Is It Time to Consider Case-Based Formats? | 2016 | Clin Pediatr (Phila) | pmid:25986442 |
| Chang CC et al. | Disseminated cat-scratch disease: case report and review of the literature. | 2016 | Paediatr Int Child Health | pmid:25940800 |