| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pain, Postoperative | D010149 | 13 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Cardiovascular Diseases | D002318 | 24 associated lipids |
| Abnormalities, Drug-Induced | D000014 | 10 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Staphylococcal Infections | D013203 | 15 associated lipids |
| Corneal Opacity | D003318 | 3 associated lipids |
| Drug Hypersensitivity | D004342 | 20 associated lipids |
| Eye Diseases | D005128 | 12 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Taylor WR et al. | Malaria prophylaxis using azithromycin: a double-blind, placebo-controlled trial in Irian Jaya, Indonesia. | 1999 | Clin. Infect. Dis. | pmid:10028075 |
| Uy HS et al. | Infectious crystalline keratopathy and endophthalmitis secondary to Mycobacterium abscessus in a monocular patient with Stevens-Johnson syndrome. | 1999 | Am. J. Ophthalmol. | pmid:10030567 |
| Bizjak ED et al. | Intravenous azithromycin-induced ototoxicity. | 1999 | Pharmacotherapy | pmid:10030778 |
| Wubbel L et al. | Etiology and treatment of community-acquired pneumonia in ambulatory children. | 1999 | Pediatr. Infect. Dis. J. | pmid:10048679 |
| O'Doherty B and Muller O | Randomized, multicentre study of the efficacy and tolerance of azithromycin versus clarithromycin in the treatment of adults with mild to moderate community-acquired pneumonia. Azithromycin Study Group. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:10052544 |
| Ogasawara KK and Goodwin TM | Efficacy of azithromycin in reducing lower genital Ureaplasma urealyticum colonization in women at risk for preterm delivery. | 1999 Jan-Feb | J Matern Fetal Med | pmid:10052839 |
| Van Bambeke F et al. | Lysosomal alterations induced in cultured rat fibroblasts by long-term exposure to low concentrations of azithromycin. | 1998 | J. Antimicrob. Chemother. | pmid:10052900 |
| Wyrick PB et al. | Persistent chlamydial envelope antigens in antibiotic-exposed infected cells trigger neutrophil chemotaxis. | 1999 | J. Infect. Dis. | pmid:10068592 |
| Shirtliff ME et al. | Oral rifampin plus azithromycin or clarithromycin to treat osteomyelitis in rabbits. | 1999 | Clin. Orthop. Relat. Res. | pmid:10078148 |
| Stamm WE | Chlamydia trachomatis infections: progress and problems. | 1999 | J. Infect. Dis. | pmid:10081511 |
| Garey KW and Amsden GW | Intravenous azithromycin. | 1999 | Ann Pharmacother | pmid:10084418 |
| Ong EL | Prophylaxis against disseminated Mycobacterium avium complex in AIDS. | 1999 | J. Infect. | pmid:10090497 |
| Anderson JL et al. | Randomized secondary prevention trial of azithromycin in patients with coronary artery disease and serological evidence for Chlamydia pneumoniae infection: The Azithromycin in Coronary Artery Disease: Elimination of Myocardial Infection with Chlamydia (ACADEMIC) study. | 1999 | Circulation | pmid:10096928 |
| Aubert JD et al. | Function of human alveolar macrophages after a 3-day course of azithromycin in healthy volunteers. | 1998 | Pulm Pharmacol Ther | pmid:10101742 |
| Breitschwerdt EB et al. | Efficacy of doxycycline, azithromycin, or trovafloxacin for treatment of experimental Rocky Mountain spotted fever in dogs. | 1999 | Antimicrob. Agents Chemother. | pmid:10103185 |
| Lea AP and Lamb HM | Azithromycin. A pharmacoeconomic review of its use as a single-dose regimen in the treatment of uncomplicated urogenital Chlamydia trachomatis infections in women. | 1997 | Pharmacoeconomics | pmid:10174326 |
| Montenez JP et al. | Interactions of macrolide antibiotics (Erythromycin A, roxithromycin, erythromycylamine [Dirithromycin], and azithromycin) with phospholipids: computer-aided conformational analysis and studies on acellular and cell culture models. | 1999 | Toxicol. Appl. Pharmacol. | pmid:10198278 |
| Laine L et al. | Once-daily therapy for H. pylori infection: a randomized comparison of four regimens. | 1999 | Am. J. Gastroenterol. | pmid:10201465 |
| Borisov I | [A new therapeutic approach in the treatment of genital chlamydial infections. Azithromycin (Sumamed)]. | 1998 | Akush Ginekol (Sofiia) | pmid:10204275 |
| Amsden GW | Pharmacological considerations in the emergence of resistance. | 1999 | Int. J. Antimicrob. Agents | pmid:10204634 |
| Retsema JA | Susceptibility and resistance emergence studies with macrolides. | 1999 | Int. J. Antimicrob. Agents | pmid:10204635 |
| Scaglione F et al. | Interpretation of middle ear fluid concentrations of antibiotics: comparison between ceftibuten, cefixime and azithromycin. | 1999 | Br J Clin Pharmacol | pmid:10215750 |
| Khan AA et al. | Effect of clarithromycin and azithromycin on production of cytokines by human monocytes. | 1999 | Int. J. Antimicrob. Agents | pmid:10221415 |
| Garey KW et al. | Lack of effect of zafirlukast on the pharmacokinetics of azithromycin, clarithromycin, and 14-hydroxyclarithromycin in healthy volunteers. | 1999 | Antimicrob. Agents Chemother. | pmid:10223928 |
| Ouadrhiri Y et al. | Mechanism of the intracellular killing and modulation of antibiotic susceptibility of Listeria monocytogenes in THP-1 macrophages activated by gamma interferon. | 1999 | Antimicrob. Agents Chemother. | pmid:10223943 |
| Könönen E et al. | beta-lactamase production and antimicrobial susceptibility of oral heterogeneous Fusobacterium nucleatum populations in young children. | 1999 | Antimicrob. Agents Chemother. | pmid:10223950 |
| Bergman KL et al. | Antimicrobial activities and postantibiotic effects of clarithromycin, 14-hydroxy-clarithromycin, and azithromycin in epithelial cell lining fluid against clinical isolates of haemophilus influenzae and Streptococcus pneumoniae. | 1999 | Antimicrob. Agents Chemother. | pmid:10223956 |
| Akova M et al. | In vitro activities of antibiotics alone and in combination against Brucella melitensis at neutral and acidic pHs. | 1999 | Antimicrob. Agents Chemother. | pmid:10223958 |
| Gorenek L et al. | The diagnosis and treatment of Clostridium difficile in antibiotic-associated diarrhea. | 1999 Jan-Feb | Hepatogastroenterology | pmid:10228818 |
| Taylor H | Towards the global elimination of trachoma. | 1999 | Nat. Med. | pmid:10229224 |
| Lietman T et al. | Global elimination of trachoma: how frequently should we administer mass chemotherapy? | 1999 | Nat. Med. | pmid:10229236 |
| Nowicki M et al. | Partial regression of advanced cyclosporin-induced gingival hyperplasia after treatment with azithromycin. A case report. | 1998 | Ann. Transplant. | pmid:10234432 |
| Carbon C and Poole MD | The role of newer macrolides in the treatment of community-acquired respiratory tract infection. A review of experimental and clinical data. | 1999 | J Chemother | pmid:10326741 |
| Cazzola M et al. | Comparative study of dirithromycin and azithromycin in the treatment of acute bacterial exacerbations of chronic bronchitis. | 1999 | J Chemother | pmid:10326742 |
| Petitta A et al. | Economic evaluation of three methods of treating urogenital chlamydial infections in the emergency department. | 1999 | Pharmacotherapy | pmid:10331829 |
| Cammarota G et al. | Three-day antibiotic therapy with azithromycin and tinidazole plus lansoprazole or pantoprazole to cure Helicobacter pylori infection: a pilot study. | 1999 | Eur J Gastroenterol Hepatol | pmid:10333196 |
| Wirnsberger GH and Pfragner R | Comment on "Efficacy of azithromycin in the treatment of cyclosporine-induced gingival hyperplasia in renal transplant recipients" by Nash and Zaltzman. | 1999 | Transplantation | pmid:10342326 |
| Girgis NI et al. | Azithromycin versus ciprofloxacin for treatment of uncomplicated typhoid fever in a randomized trial in Egypt that included patients with multidrug resistance. | 1999 | Antimicrob. Agents Chemother. | pmid:10348767 |
| Wolf K and Malinverni R | Effect of azithromycin plus rifampin versus that of azithromycin alone on the eradication of Chlamydia pneumoniae from lung tissue in experimental pneumonitis. | 1999 | Antimicrob. Agents Chemother. | pmid:10348778 |
| Ngo LY et al. | Pharmacokinetics of azithromycin administered alone and with atovaquone in human immunodeficiency virus-infected children. The ACTG 254 Team. | 1999 | Antimicrob. Agents Chemother. | pmid:10348786 |
| Vcev A et al. | High dose omeprazole plus amoxicillin and azithromycin in eradication of Helicobacter pylori in duodenal ulcers. | 1999 | Helicobacter | pmid:10352088 |
| Cinti S et al. | Killing of Mycobacterium avium by neutrophils and monocytes from AIDS patients treated with recombinant granulocyte-macrophage colony-stimulating factor. | 1999 | J. Infect. Dis. | pmid:10353887 |
| Walterspiel JN | Treatment of cat scratch disease. | 1999 | N. Engl. J. Med. | pmid:10366328 |
| Johnson JR | Therapy for Legionnaires disease. | 1999 | Ann. Intern. Med. | pmid:10366385 |
| Preheim LC et al. | Ethanol feeding does not affect the efficacy or pharmacokinetics of azithromycin, trovafloxacin, or ceftriaxone in a rat model of pneumococcal pneumonia. | 1999 | Alcohol. Clin. Exp. Res. | pmid:10371404 |
| Dimitrakov J et al. | A case of Chlamydia trachomatis infection in a renal allograft patient. | 1998 | Folia Med (Plovdiv) | pmid:10371799 |
| Alvarez-Elcoro S and Enzler MJ | The macrolides: erythromycin, clarithromycin, and azithromycin. | 1999 | Mayo Clin. Proc. | pmid:10377939 |
| Schönwald S et al. | Azithromycin: single 1.5 g dose in the treatment of patients with atypical pneumonia syndrome--a randomized study. | 1999 May-Jun | Infection | pmid:10378132 |
| Lombardo L et al. | Helicobacter pylori eradication using one-week low-dose lansoprazole plus amoxycillin and azithromycin: failure of a "promising" association. | 1999 | Ital J Gastroenterol Hepatol | pmid:10379493 |