Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Pain, Postoperative D010149 13 associated lipids
Weight Gain D015430 101 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Abnormalities, Drug-Induced D000014 10 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Corneal Opacity D003318 3 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Eye Diseases D005128 12 associated lipids
Arteriosclerosis D001161 86 associated lipids
Per page 10 20 50 100 | Total 276

PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Sidhu H et al. Risk assessment of biosolids-borne ciprofloxacin and azithromycin. 2019 Sci. Total Environ. pmid:30463165
Sidhu H et al. Plant toxicity and accumulation of biosolids-borne ciprofloxacin and azithromycin. 2019 Sci. Total Environ. pmid:30340267
Sidhu H et al. Retention-release of ciprofloxacin and azithromycin in biosolids and biosolids-amended soils. 2019 Sci. Total Environ. pmid:30196217
Sidhu H et al. Bioavailability of biosolids-borne ciprofloxacin and azithromycin to terrestrial organisms: Microbial toxicity and earthworm responses. 2019 Sci. Total Environ. pmid:30195128
Latif AS et al. Antimicrobial susceptibility in isolates from five sentinel surveillance sites in Zimbabwe, 2015-2016. 2018 Sex Transm Infect pmid:28476914
Šmajs D and Pospíšilová P Macrolide resistance in yaws. 2018 Lancet pmid:29428184
Mitjà O et al. Re-emergence of yaws after single mass azithromycin treatment followed by targeted treatment: a longitudinal study. 2018 Lancet pmid:29428183
Brereton CJ et al. Is gentamicin safe and effective for severe community-acquired pneumonia? An 8-year retrospective cohort study. 2018 Int. J. Antimicrob. Agents pmid:29410326
Ting CY and Shahdadpuri R Fuchs syndrome: a case of fever, mucositis and conjunctivitis. 2018 BMJ Case Rep pmid:29378740
Huang S et al. Human babesiosis in Southeast China: A case report. 2018 Int. J. Infect. Dis. pmid:29355731
Jenson A et al. Patient-centered communication of community treatment assistants in Tanzania predicts coverage of future mass drug administration for trachoma. 2018 Patient Educ Couns pmid:29329726
Sarathchandran P et al. infection presenting as stroke and meningoencephalitis with aortic and subclavian aneurysms without pulmonary involvement. 2018 BMJ Case Rep pmid:29326371
Mascarenhas TR et al. Tick-borne illness after transplantation: Case and review. 2018 Transpl Infect Dis pmid:29277955
Oldenburg CE et al. Comparison of Mass Azithromycin Coverage Targets of Children in Niger: A Cluster-Randomized Trachoma Trial. 2018 Am. J. Trop. Med. Hyg. pmid:29260659
Medeiros PHQS et al. Molecular characterization of virulence and antimicrobial resistance profile of Shigella species isolated from children with moderate to severe diarrhea in northeastern Brazil. 2018 Diagn. Microbiol. Infect. Dis. pmid:29217418
Kelly C et al. Macrolide antibiotics for bronchiectasis. 2018 Cochrane Database Syst Rev pmid:29543980
Casas-Maldonado F Bronchiectasis and Azithromycin. 2018 Arch. Bronconeumol. pmid:28757281
Zhao L et al. Trends in antimicrobial resistance in Neisseria gonorrhoeae and molecular characteristics of N. gonorrhoeae with decreased susceptibility to ceftriaxone in Shandong, China, 2007 to 2014. 2018 Int. J. Antimicrob. Agents pmid:28729124
Bakshi SS In reference to 'Therapeutic efficacy of azithromycin and acetylcysteine in chronic otitis media with effusion'. 2018 Eur Arch Otorhinolaryngol pmid:28612316
Weston EJ et al. Adherence to CDC Recommendations for the Treatment of Uncomplicated Gonorrhea - STD Surveillance Network, United States, 2016. 2018 MMWR Morb. Mortal. Wkly. Rep. pmid:29698384
Revello R et al. Prediction of chorioamnionitis in cases of intraamniotic infection by ureaplasma urealyticum in women with very preterm premature rupture of membranes or preterm labour. 2018 J. Matern. Fetal. Neonatal. Med. pmid:28502201
Keenan JD et al. Azithromycin to Reduce Childhood Mortality in Sub-Saharan Africa. 2018 N. Engl. J. Med. pmid:29694816
Marks M et al. Comparative efficacy of low-dose versus standard-dose azithromycin for patients with yaws: a randomised non-inferiority trial in Ghana and Papua New Guinea. 2018 Lancet Glob Health pmid:29456191
Sardana K et al. An observational study of the efficacy of azithromycin in erythema annulare centrifugum. 2018 Clin. Exp. Dermatol. pmid:29297941
Lietman TM et al. Identifying a sufficient core group for trachoma transmission. 2018 PLoS Negl Trop Dis pmid:30296259
Hassan KS and Al-Khadouri G Pneumonia with Worsening Pleural Effusion Despite Treatment with Appropriate Antimicrobials: Case report. 2018 Sultan Qaboos Univ Med J pmid:30210860
Williams PCM and Berkley JA Guidelines for the management of paediatric cholera infection: a systematic review of the evidence. 2018 Paediatr Int Child Health pmid:29790841
Al-Darraji A et al. Azithromycin therapy reduces cardiac inflammation and mitigates adverse cardiac remodeling after myocardial infarction: Potential therapeutic targets in ischemic heart disease. 2018 PLoS ONE pmid:30001416
Glanternik JR et al. A Cluster of Cases of Babesia microti Among Neonates Traced to a Single Unit of Donor Blood. 2018 Pediatr. Infect. Dis. J. pmid:28945680
Vermillion Maier ML and Tjeerdema RS Azithromycin sorption and biodegradation in a simulated California river system. 2018 Chemosphere pmid:29031188
Tada H et al. The effects of Lactobacillus reuteri probiotics combined with azithromycin on peri-implantitis: A randomized placebo-controlled study. 2018 J Prosthodont Res pmid:28756115
Fleming-Dutra KE et al. Variations in Antibiotic and Azithromycin Prescribing for Children by Geography and Specialty-United States, 2013. 2018 Pediatr. Infect. Dis. J. pmid:28746259
Balci O and Gulkilik G Assessment of efficacy of topical azithromycin 1.5 per cent ophthalmic solution for the treatment of meibomian gland dysfunction. 2018 Clin Exp Optom pmid:28677153
Obaro S Azithromycin and Childhood Mortality in Africa. 2018 N. Engl. J. Med. pmid:30284804
Michelow IC and Sánchez PJ Azithromycin and Childhood Mortality in Africa. 2018 N. Engl. J. Med. pmid:30284803
Cutler T et al. Azithromycin and Childhood Mortality in Africa. 2018 N. Engl. J. Med. pmid:30284802
Keenan JD et al. Azithromycin and Childhood Mortality in Africa. 2018 N. Engl. J. Med. pmid:30281987
Smotrys M et al. Babesiosis as a cause of false-positive HIV serology. 2018 BMJ Case Rep pmid:29884713
Nüesch-Inderbinen M et al. Genetic characterization of Shiga toxin producing Escherichia coli belonging to the emerging hybrid pathotype O80:H2 isolated from humans 2010-2017 in Switzerland. 2018 Int. J. Med. Microbiol. pmid:29884331
Iguidbashian JP et al. and coinfection in the setting of ulcerative colitis. 2018 BMJ Case Rep pmid:29880626
Lendermon EA et al. Azithromycin Fails to Prevent Accelerated Airway Obliteration in T-bet Mouse Lung Allograft Recipients. 2018 Transplant. Proc. pmid:29880387
Lam-Franco L et al. IL-1α and MMP-9 Tear Levels of Patients with Active Ocular Rosacea before and after Treatment with Systemic Azithromycin or Doxycycline. 2018 Ophthalmic Res. pmid:29874670
Saita MG et al. pH-Dependent stability of azithromycin in aqueous solution and structure identification of two new degradation products. 2018 J Pharm Biomed Anal pmid:29860178
Naderi N et al. Long-term azithromycin therapy to reduce acute exacerbations in patients with severe chronic obstructive pulmonary disease. 2018 Respir Med pmid:29724384
Zmora N et al. Open label comparative trial of mono versus dual antibiotic therapy for Typhoid Fever in adults. 2018 PLoS Negl Trop Dis pmid:29684022
Wei W et al. MPEG-PCL Copolymeric Micelles for Encapsulation of Azithromycin. 2018 AAPS PharmSciTech pmid:29675667
Barge L et al. Transient immune-mediated agranulocytosis following infection. 2018 BMJ Case Rep pmid:29669774
Baker KS et al. Horizontal antimicrobial resistance transfer drives epidemics of multiple Shigella species. 2018 Nat Commun pmid:29654279
Ganesh R et al. Clinical profile and outcome of children with scrub typhus from Chennai, South India. 2018 Eur. J. Pediatr. pmid:29637374
Deguchi T et al. Macrolide and fluoroquinolone resistance is uncommon in clinical strains of Chlamydia trachomatis. 2018 J. Infect. Chemother. pmid:29627327