Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Pain, Postoperative D010149 13 associated lipids
Weight Gain D015430 101 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Abnormalities, Drug-Induced D000014 10 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Corneal Opacity D003318 3 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Eye Diseases D005128 12 associated lipids
Arteriosclerosis D001161 86 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Scharfstein JA et al. The cost-effectiveness of prophylaxis for Mycobacterium avium complex in AIDS. 1999 Int J Technol Assess Health Care pmid:10874380
SendaÄŸ F et al. Single dose oral azithromycin versus seven day doxycycline in the treatment of non-gonococcal mucopurulent endocervicitis. 2000 Aust N Z J Obstet Gynaecol pmid:10870778
Miltner EC and Bermudez LE Mycobacterium avium grown in Acanthamoeba castellanii is protected from the effects of antimicrobials. 2000 Antimicrob. Agents Chemother. pmid:10858369
Chinh NT et al. A randomized controlled comparison of azithromycin and ofloxacin for treatment of multidrug-resistant or nalidixic acid-resistant enteric fever. 2000 Antimicrob. Agents Chemother. pmid:10858343
Plouffe J et al. Clinical efficacy of intravenous followed by oral azithromycin monotherapy in hospitalized patients with community-acquired pneumonia. The Azithromycin Intravenous Clinical Trials Group. 2000 Antimicrob. Agents Chemother. pmid:10858333
Criqui GI et al. Effects of azithromycin on ozone-induced airway neutrophilia and cytokine release. 2000 Eur. Respir. J. pmid:10853849
Ernst EJ et al. Comparison of the serum and intracellular pharmacokinetics of azithromycin in healthy and diabetic volunteers. 2000 Pharmacotherapy pmid:10853621
Raja Babu KK et al. Confluent and reticulate papillomatosis: successful treatment with azithromycin. 2000 Br. J. Dermatol. pmid:10848767
Heikkinen T et al. The transplacental transfer of the macrolide antibiotics erythromycin, roxithromycin and azithromycin. 2000 BJOG pmid:10847234
Jackson LA Description and status of the azithromycin and coronary events study (ACES). 2000 J. Infect. Dis. pmid:10839763
Dunne MW Rationale and design of a secondary prevention trial of antibiotic use in patients after myocardial infarction: the WIZARD (weekly intervention with zithromax [azithromycin] for atherosclerosis and its related disorders) trial. 2000 J. Infect. Dis. pmid:10839762
Anderson JL and Muhlestein JB The ACADEMIC study in perspective (Azithromycin in coronary artery disease: elimination of myocardial infection with Chlamydia). 2000 J. Infect. Dis. pmid:10839761
Matute AJ et al. Is a 5 day course of azithromycin enough for infections caused by Legionella pneumophila? 2000 J. Antimicrob. Chemother. pmid:10837459
Moshkani SK and Dalimi A Evaluation of the efficacy of atovaquone alone or in combination with azithromycin against acute murine toxoplasmosis. 2000 Vet. Res. Commun. pmid:10836275
Straubinger RK PCR-Based quantification of Borrelia burgdorferi organisms in canine tissues over a 500-Day postinfection period. 2000 J. Clin. Microbiol. pmid:10834975
Mirmiran R et al. Disseminated gonococcal infection: a case of beta-lactamase-producing Neisseria gonorrhoeae. 2000 J Am Podiatr Med Assoc pmid:10833879
Zuckerman JM The newer macrolides: azithromycin and clarithromycin. 2000 Infect. Dis. Clin. North Am. pmid:10829265
Bin XX et al. Effect of azithromycin plus rifampin versus amoxicillin alone on eradication and inflammation in the chronic course of Chlamydia pneumoniae pneumonitis in mice. 2000 Antimicrob. Agents Chemother. pmid:10817751
Tsitsika A et al. Single-oral-dose azithromycin prophylaxis against experimental streptococcal or staphylococcal aortic valve endocarditis. 2000 Antimicrob. Agents Chemother. pmid:10817749
Turcinov D et al. Failure of azithromycin in treatment of Brill-Zinsser disease. 2000 Antimicrob. Agents Chemother. pmid:10817744