Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Bites, Human D001734 2 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
Herpes Genitalis D006558 2 associated lipids
Ciliary Motility Disorders D002925 2 associated lipids
Tuberculosis, Avian D014379 2 associated lipids
Amebiasis D000562 2 associated lipids
Giardiasis D005873 3 associated lipids
Otorhinolaryngologic Diseases D010038 3 associated lipids
Gingival Hyperplasia D005885 3 associated lipids
Dry Socket D004368 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Stoney RJ et al. Travelers' Diarrhea and Other Gastrointestinal Symptoms Among Boston-Area International Travelers. 2017 Am. J. Trop. Med. Hyg. pmid:28719282
Harper LM et al. Economic Evaluation of Adjunctive Azithromycin Prophylaxis for Cesarean Delivery. 2017 Obstet Gynecol pmid:28697108
Fan LC et al. Macrolides protect against infection via inhibition of inflammasomes. 2017 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:28684545
Bystrzycka W et al. Azithromycin and Chloramphenicol Diminish Neutrophil Extracellular Traps (NETs) Release. 2017 Int J Mol Sci pmid:29292737
Pavlinac PB et al. Azithromycin to prevent post-discharge morbidity and mortality in Kenyan children: a protocol for a randomised, double-blind, placebo-controlled trial (the Toto Bora trial). 2017 BMJ Open pmid:29289941
Ullah S et al. Creatinine-based non-phospholipid vesicular carrier for improved oral bioavailability of Azithromycin. 2017 Drug Dev Ind Pharm pmid:28157445
Mohammed H et al. First line dual therapy for gonorrhoea to limit the spread of antimicrobial resistance. 2017 BMJ pmid:28153820
Oluwalana C et al. Azithromycin in Labor Lowers Clinical Infections in Mothers and Newborns: A Double-Blind Trial. 2017 Pediatrics pmid:28130432
Gerber JS and Zaoutis TE Azithromycin Prophylaxis for Laboring Mothers. 2017 Pediatrics pmid:28130431
Gibson PG et al. Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial. 2017 Lancet pmid:28687413
Molefe NI et al. Oral administration of azithromycin ameliorates trypanosomosis in Trypanosoma congolense-infected mice. 2017 Parasitol. Res. pmid:28674747
Batteiger BE Azithromycin Efficacy in Asymptomatic Rectal Chlamydial Infection in Men Who Have Sex With Men: A More Definitive Answer Soon? 2017 Sex Transm Dis pmid:28604482
Haque F et al. Evaluation of a Smartphone Decision-Support Tool for Diarrheal Disease Management in a Resource-Limited Setting. 2017 PLoS Negl Trop Dis pmid:28103233
Bulman ZP et al. Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin. 2017 Antimicrob. Agents Chemother. pmid:28096154
Björnelius E et al. macrolide resistance in Stockholm, Sweden. 2017 Sex Transm Infect pmid:27502694
O'Rourke VJ Azithromycin as an adjunct to non-surgical periodontal therapy: a systematic review. 2017 Aust Dent J pmid:27492140
Xue Y et al. An in vitro model of azithromycin-induced persistent Chlamydia trachomatis infection. 2017 FEMS Microbiol. Lett. pmid:28854672
Barberá MJ et al. Mycoplasma genitalium Macrolide and Fluoroquinolone Resistance: Prevalence and Risk Factors Among a 2013-2014 Cohort of Patients in Barcelona, Spain. 2017 Sex Transm Dis pmid:28703723
Nichols DP et al. Impact of azithromycin on the clinical and antimicrobial effectiveness of tobramycin in the treatment of cystic fibrosis. 2017 J. Cyst. Fibros. pmid:28025037
Marks M et al. Mathematical Modeling of Programmatic Requirements for Yaws Eradication. 2017 Emerging Infect. Dis. pmid:27983500