Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Vranes J et al. | Influence of subinhibitory concentrations of ceftazidime, ciprofloxacin and azithromycin on the morphology and adherence of P-fimbriated escherichia coli. | 1996 | J Chemother | pmid:8873829 |
| Laing RB et al. | Clinical features, outcome and survival from cerebral toxoplasmosis in Edinburgh AIDS patients. | 1996 | Int J STD AIDS | pmid:8876356 |
| Tansey MJ and Moe JB | Severe neutropenia and prophylactic doses of rifabutin. | 1996 | Lancet | pmid:8950911 |
| Sefton AM et al. | Azithromycin in the treatment of periodontal disease. Effect on microbial flora. | 1996 | J. Clin. Periodontol. | pmid:8951627 |
| Griffith DE et al. | Varying dosages of rifabutin affect white blood cell and platelet counts in human immunodeficiency virus--negative patients who are receiving multidrug regimens for pulmonary Mycobacterium avium complex disease. | 1996 | Clin. Infect. Dis. | pmid:8953085 |
| Clearance to market azithromycin as prevention for a common OI in advanced AIDS. | 1996 | AIDS Patient Care STDS | pmid:11361535 | |
| Prophylactic antibiotic receives speedy FDA approval to reduce MAC disease in advanced HIV. | 1996 | AIDS Patient Care STDS | pmid:11361569 | |
| Azithromycin and OIs. | 1996 | AIDS Patient Care STDS | pmid:11361699 | |
| Segreti J et al. | In vitro activity of macrolides against intracellular Legionella pneumophila. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8902407 |
| Na-Bangchang K et al. | Activity of artemether-azithromycin versus artemether-doxycycline in the treatment of multiple drug resistant falciparum malaria. | 1996 | Southeast Asian J. Trop. Med. Public Health | pmid:9185262 |
| Lode H et al. | Azithromycin--review of key chemical, pharmacokinetic and microbiological features. | 1996 | J. Antimicrob. Chemother. | pmid:8818841 |
| Girard AE et al. | Correlation of increased azithromycin concentrations with phagocyte infiltration into sites of localized infection. | 1996 | J. Antimicrob. Chemother. | pmid:8818842 |
| Girard D et al. | Influence of immunosuppression on the pharmacokinetics and pharmacodynamics of azithromycin in infected mouse tissues. | 1996 | J. Antimicrob. Chemother. | pmid:8818843 |
| Foulds G et al. | The absence of an effect of food on the bioavailability of azithromycin administered as tablets, sachet or suspension. | 1996 | J. Antimicrob. Chemother. | pmid:8818844 |
| Vaudaux BP et al. | Concentrations of azithromycin in tonsilar and/or adenoid tissue from paediatric patients. | 1996 | J. Antimicrob. Chemother. | pmid:8818845 |
| Pukander J and Rautianen M | Penetration of azithromycin into middle ear effusions in acute and secretory otitis media in children. | 1996 | J. Antimicrob. Chemother. | pmid:8818846 |
| Rodriguez AF | An open study to compare azithromycin with cefaclor in the treatment of children with acute otitis media. | 1996 | J. Antimicrob. Chemother. | pmid:8818847 |
| O'Doherty B | An open comparative study of azithromycin versus cefaclor in the treatment of patients with upper respiratory tract infections. | 1996 | J. Antimicrob. Chemother. | pmid:8818848 |
| Müller O | An open comparative study of azithromycin and roxithromycin in the treatment of acute upper respiratory tract infections. | 1996 | J. Antimicrob. Chemother. | pmid:8818849 |
| Gris P | Once-daily, 3-day azithromycin versus a three-times-daily, 10-day course of co-amoxiclav in the treatment of adults with lower respiratory tract infections: results of a randomized, double-blind comparative study. | 1996 | J. Antimicrob. Chemother. | pmid:8818850 |
| Akita H et al. | [Bacteriological, pharmacokinetic and clinical evaluation of azithromycin in the pediatric field]. | 1996 | Jpn J Antibiot | pmid:8986553 |
| Nishimura T et al. | [Clinical evaluation of azithromycin in pediatric infections]. | 1996 | Jpn J Antibiot | pmid:8986554 |
| Haruta T and Kobayashi Y | [Therapeutic efficacy of azithromycin in pediatrics]. | 1996 | Jpn J Antibiot | pmid:8986555 |
| Kuroda Y and Ito M | [Therapy with azithromycin in pediatric infections]. | 1996 | Jpn J Antibiot | pmid:8986556 |
| Waugh MA | Azithromycin in gonorrhoea. | 1996 | Int J STD AIDS | pmid:8652723 |
| Okamoto T and Sekiguchi T | [Clinical studies on azithromycin in pediatrics]. | 1996 | Jpn J Antibiot | pmid:8986557 |
| Young LS | Treatment and prophylaxis of Mycobacterium avium complex. | 1996 | Int J STD AIDS | pmid:8652724 |
| Toyonaga Y et al. | [Pharmacokinetic and clinical evaluation of azithromycin using fine granules or capsules in the pediatric patients]. | 1996 | Jpn J Antibiot | pmid:8988410 |
| Hoepelman IM | Human cryptosporidiosis. | 1996 | Int J STD AIDS | pmid:8652725 |
| Okumura A and Kuno K | [Pharmacokinetic and clinical evaluation of azithromycin in pediatrics]. | 1996 | Jpn J Antibiot | pmid:8988411 |
| McCutchan JA | Azithromycin in the prophylaxis of opportunistic infections in AIDS. | 1996 | Int J STD AIDS | pmid:8652726 |
| Kobayashi Y et al. | [Clinical study of a macrolide antibiotic, azithromycin, in pediatric patients]. | 1996 | Jpn J Antibiot | pmid:8988412 |
| Ridgway GL | Azithromycin in the management of Chlamydia trachomatis infections. | 1996 | Int J STD AIDS | pmid:8652727 |
| Furukawa S and Okada T | [A clinical evaluation of azithromycin in the treatment of pediatric infection]. | 1996 | Jpn J Antibiot | pmid:8988413 |
| Ballard RC et al. | Treatment of chancroid with azithromycin. | 1996 | Int J STD AIDS | pmid:8652728 |
| Bowden FJ et al. | Pilot study of azithromycin in the treatment of genital donovanosis. | 1996 | Genitourin Med | pmid:8655160 |
| Kohl PK et al. | Gonorrhoea: single-dose oral treatment. | 1996 | Curr. Probl. Dermatol. | pmid:8743257 |
| Nickel P and Näher H | Nongonococcal urethritis. | 1996 | Curr. Probl. Dermatol. | pmid:8743259 |
| Hayle R et al. | Efficacy and safety of azithromycin versus phenoxymethylpenicillin in the treatment of acute maxillary sinusitis. | 1996 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8997555 |
| Adhikari P et al. | Evaluation of safety and efficacy of azithromycin in lower respiratory tract infections (LRTI) | 1996 | Indian J Med Sci | pmid:9057364 |
| Thylefors B | Trachoma--new opportunities to tackle an old problem. | 1996 | Br J Ophthalmol | pmid:9059262 |
| Magid D et al. | Doxycycline compared with azithromycin for treating women with genital Chlamydia trachomatis infections: an incremental cost-effectiveness analysis. | 1996 | Ann. Intern. Med. | pmid:8554247 |
| Three new studies expand understanding of MAC therapy. | 1996 | Am J Health Syst Pharm | pmid:8899122 | |
| Evans LA et al. | Predicting injection site muscle damage. III: Evaluation of intramuscular formulations in the L6 cell model. | 1996 | Pharm. Res. | pmid:8899856 |
| O'Doherty B | Azithromycin versus penicillin V in the treatment of paediatric patients with acute streptococcal pharyngitis/tonsillitis. Paediatric Azithromycin Study Group. | 1996 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8922571 |
| Cellesi C et al. | Susceptibility of macrolide and beta-lactam antibiotics of Streptococcus pyogenes strains isolated over a four-year period in central Italy. | 1996 | J Chemother | pmid:8808714 |
| Delmée M et al. | In vitro susceptibilities of 180 clinical isolates of Haemophilus influenzae to ampicillin, amoxycillin/clavulanate, cefaclor, cefuroxime, cefotaxime, clarithromycin, and azithromycin. | 1996 | Acta Clin Belg | pmid:8858889 |
| Watt B et al. | Comparative activity of azithromycin against clinical isolates of mycobacteria. | 1996 | J. Antimicrob. Chemother. | pmid:8889727 |
| Mashkilleyson AL et al. | Treatment of syphilis with azithromycin. | 1996 | Int J STD AIDS | pmid:8652720 |
| Patel KB et al. | Comparison of bronchopulmonary pharmacokinetics of clarithromycin and azithromycin. | 1996 | Antimicrob. Agents Chemother. | pmid:8891147 |