Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Central Nervous System Protozoal Infections D020808 3 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Chlamydophila Infections D023521 4 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Mucositis D052016 7 associated lipids
Tendinopathy D052256 3 associated lipids
Male Urogenital Diseases D052801 1 associated lipids
Pyomyositis D052880 2 associated lipids
Hyper-IgM Immunodeficiency Syndrome D053306 1 associated lipids
Precursor Cell Lymphoblastic Leukemia-Lymphoma D054198 10 associated lipids
Tracheobronchomalacia D055089 1 associated lipids
Failed Back Surgery Syndrome D055111 3 associated lipids
Acute Lung Injury D055371 33 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
Corneal Endothelial Cell Loss D055954 1 associated lipids
Neglected Diseases D058069 3 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Asymptomatic Infections D058345 1 associated lipids
Trichiasis D058457 1 associated lipids
Granulomatous Mastitis D058890 1 associated lipids
Reproductive Tract Infections D060737 1 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Tick Bites D064927 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Di Mario F et al. Azithromycin for the cure of Helicobacter pylori infection. 1996 Am. J. Gastroenterol. pmid:8607490
Luft BJ et al. Azithromycin compared with amoxicillin in the treatment of erythema migrans. A double-blind, randomized, controlled trial. 1996 Ann. Intern. Med. pmid:8610947
Tabbara KF et al. Single-dose azithromycin in the treatment of trachoma. A randomized, controlled study. 1996 Ophthalmology pmid:8637698
Tribble D et al. Efficacy of azithromycin for typhoid fever. 1995 Clin. Infect. Dis. pmid:8645805
Ridgway GL Azithromycin in sexually transmitted diseases. 1996 Int J STD AIDS pmid:8652719
Mashkilleyson AL et al. Treatment of syphilis with azithromycin. 1996 Int J STD AIDS pmid:8652720
Young LS Azithromycin in the management of opportunistic infections. 1996 Int J STD AIDS pmid:8652721
Chang HR The potential role of azithromycin in the treatment of prophylaxis of toxoplasmosis. 1996 Int J STD AIDS pmid:8652722
Waugh MA Azithromycin in gonorrhoea. 1996 Int J STD AIDS pmid:8652723
Young LS Treatment and prophylaxis of Mycobacterium avium complex. 1996 Int J STD AIDS pmid:8652724
Hoepelman IM Human cryptosporidiosis. 1996 Int J STD AIDS pmid:8652725
McCutchan JA Azithromycin in the prophylaxis of opportunistic infections in AIDS. 1996 Int J STD AIDS pmid:8652726
Ridgway GL Azithromycin in the management of Chlamydia trachomatis infections. 1996 Int J STD AIDS pmid:8652727
Ballard RC et al. Treatment of chancroid with azithromycin. 1996 Int J STD AIDS pmid:8652728
Bowden FJ et al. Pilot study of azithromycin in the treatment of genital donovanosis. 1996 Genitourin Med pmid:8655160
Höffler D et al. Pharmacokinetics of azithromycin in normal and impaired renal function. 1995 Nov-Dec Infection pmid:8655206
Havlir DV et al. Prophylaxis against disseminated Mycobacterium avium complex with weekly azithromycin, daily rifabutin, or both. California Collaborative Treatment Group. 1996 N. Engl. J. Med. pmid:8676932
Tursi A et al. The use of azithromycin in short-term low-dose triple therapies for Helicobacter pylori infection. 1996 Am. J. Gastroenterol. pmid:8677967
Thorpe EM et al. Chlamydial cervicitis and urethritis: single dose treatment compared with doxycycline for seven days in community based practises. 1996 Genitourin Med pmid:8698374
Caselli M et al. A comparative trial of short term therapy with omeprazole plus either amoxycillin or azithromycin for Helicobacter pylori eradication. 1996 J. Antimicrob. Chemother. pmid:8722557
Falagas ME and Klempner MS Babesiosis in patients with AIDS: a chronic infection presenting as fever of unknown origin. 1996 Clin. Infect. Dis. pmid:8722936
Murphy GS et al. Ciprofloxacin- and azithromycin-resistant Campylobacter causing traveler's diarrhea in U.S. troops deployed to Thailand in 1994. 1996 Clin. Infect. Dis. pmid:8722958
Scorneaux B et al. Effect of recombinant human gamma interferon on intracellular activities of antibiotics against Listeria monocytogenes in the human macrophage cell line THP-1. 1996 Antimicrob. Agents Chemother. pmid:8723471
Wilton LV et al. A comparison of ciprofloxacin, norfloxacin, ofloxacin, azithromycin and cefixime examined by observational cohort studies. 1996 Br J Clin Pharmacol pmid:8730972
Kohl PK et al. Gonorrhoea: single-dose oral treatment. 1996 Curr. Probl. Dermatol. pmid:8743257
Nickel P and Näher H Nongonococcal urethritis. 1996 Curr. Probl. Dermatol. pmid:8743259
Johnson RB Azithromycin. 1996 Curr. Probl. Dermatol. pmid:8743269
Sternon J et al. Azithromycin compared with clarithromycin in the treatment of adult patients with acute purulent tracheobronchitis: a cost of illness study. 1995 Nov-Dec J. Int. Med. Res. pmid:8746608
Dupont C et al. Microbiological findings about pulmonary cryptosporidiosis in two AIDS patients. 1996 J. Clin. Microbiol. pmid:8748314
Fontán PA et al. Haemophilus influenzae type b exoproducts induce chemotaxis and macrolide antibiotic release by human polymorphonuclear leukocytes. 1996 Jan-Feb Chemotherapy pmid:8751269
Shanks GD et al. Azithromycin prophylaxis prevents epidemic dysentery. 1996 May-Jun Trans. R. Soc. Trop. Med. Hyg. pmid:8758091
ZaÄ­tseva EA et al. [Comparative study of the antimicrobial activity of pefloxacin, ciprofloxacin, norfloxacin and azithromycin with respect to Strains of Yersinia pseudotuberculosis]. 1996 Antibiot. Khimioter. pmid:8762820
Hicks P et al. Azithromycin therapy for Cryptosporidium parvum infection in four children infected with human immunodeficiency virus. 1996 J. Pediatr. pmid:8765631
Boran M et al. Improvement in cyclosporine A associated gingival hyperplasia with azithromycin therapy. 1996 Transplant. Proc. pmid:8769234
Wittner M et al. Atovaquone in the treatment of Babesia microti infections in hamsters. 1996 Am. J. Trop. Med. Hyg. pmid:8780464
Apseloff G et al. Severe neutropenia caused by recommended prophylactic doses of rifabutin. 1996 Lancet pmid:8782773
Wildfeuer A et al. Uptake of azithromycin by various cells and its intracellular activity under in vivo conditions. 1996 Antimicrob. Agents Chemother. pmid:8787883
Welsh L et al. In vitro activities of azithromycin, clarithromycin, erythromycin, and tetracycline against 13 strains of Chlamydia pneumoniae. 1996 Antimicrob. Agents Chemother. pmid:8787907
Mehaffey PC et al. Evaluation of in vitro spectra of activity of azithromycin, clarithromycin, and erythromycin tested against strains of Neisseria gonorrhoeae by reference agar dilution, disk diffusion, and Etest methods. 1996 J. Clin. Microbiol. pmid:8789046
Carlin EM and Barton SE Azithromycin as the first-line treatment of non-gonococcal urethritis (NGU): a study of follow-up rates, contact attendance and patients' treatment preference. 1996 May-Jun Int J STD AIDS pmid:8799780
Conte JE et al. Single-dose intrapulmonary pharmacokinetics of azithromycin, clarithromycin, ciprofloxacin, and cefuroxime in volunteer subjects. 1996 Antimicrob. Agents Chemother. pmid:8807050
Nash KA and Inderlied CB Rapid detection of mutations associated with macrolide resistance in Mycobacterium avium complex. 1996 Antimicrob. Agents Chemother. pmid:8807078
Cellesi C et al. Susceptibility of macrolide and beta-lactam antibiotics of Streptococcus pyogenes strains isolated over a four-year period in central Italy. 1996 J Chemother pmid:8808714
Adam D et al. Re: A. Bauernfeind et al.: Comparative pharmacodynamics of clarithromycin and azithromycin against respiratory pathogens (Infection 23 [1995] 316-321) 1996 May-Jun Infection pmid:8811372
Lode H et al. Azithromycin--review of key chemical, pharmacokinetic and microbiological features. 1996 J. Antimicrob. Chemother. pmid:8818841
Girard AE et al. Correlation of increased azithromycin concentrations with phagocyte infiltration into sites of localized infection. 1996 J. Antimicrob. Chemother. pmid:8818842
Girard D et al. Influence of immunosuppression on the pharmacokinetics and pharmacodynamics of azithromycin in infected mouse tissues. 1996 J. Antimicrob. Chemother. pmid:8818843
Foulds G et al. The absence of an effect of food on the bioavailability of azithromycin administered as tablets, sachet or suspension. 1996 J. Antimicrob. Chemother. pmid:8818844
Vaudaux BP et al. Concentrations of azithromycin in tonsilar and/or adenoid tissue from paediatric patients. 1996 J. Antimicrob. Chemother. pmid:8818845
Pukander J and Rautianen M Penetration of azithromycin into middle ear effusions in acute and secretory otitis media in children. 1996 J. Antimicrob. Chemother. pmid:8818846
Rodriguez AF An open study to compare azithromycin with cefaclor in the treatment of children with acute otitis media. 1996 J. Antimicrob. Chemother. pmid:8818847
O'Doherty B An open comparative study of azithromycin versus cefaclor in the treatment of patients with upper respiratory tract infections. 1996 J. Antimicrob. Chemother. pmid:8818848
Müller O An open comparative study of azithromycin and roxithromycin in the treatment of acute upper respiratory tract infections. 1996 J. Antimicrob. Chemother. pmid:8818849
Gris P Once-daily, 3-day azithromycin versus a three-times-daily, 10-day course of co-amoxiclav in the treatment of adults with lower respiratory tract infections: results of a randomized, double-blind comparative study. 1996 J. Antimicrob. Chemother. pmid:8818850
Zachariah J A randomized, comparative study to evaluate the efficacy and tolerability of a 3-day course of azithromycin versus a 10-day course of co-amoxiclav as treatment of adult patients with lower respiratory tract infections. 1996 J. Antimicrob. Chemother. pmid:8818851
Laurent K Efficacy, safety and tolerability of azithromycin versus roxithromycin in the treatment of acute lower respiratory tract infections. 1996 J. Antimicrob. Chemother. pmid:8818852
Montero L A comparative study of the efficacy, safety and tolerability of azithromycin and cefaclor in the treatment of children with acute skin and/or soft tissue infections. 1996 J. Antimicrob. Chemother. pmid:8818853
Nahata M Drug interactions with azithromycin and the macrolides: an overview. 1996 J. Antimicrob. Chemother. pmid:8818854
Treadway G and Pontani D Paediatric safety of azithromycin: worldwide experience. 1996 J. Antimicrob. Chemother. pmid:8818855
Carbon C et al. Economic analysis of antibiotic regimens used in the treatment pharyngitis: a prospective comparison of azithromycin versus roxithromycin. 1996 J. Antimicrob. Chemother. pmid:8818856
Silvestri M et al. Azithromycin induces in vitro a time-dependent increase in the intracellular killing of Staphylococcus aureus by human polymorphonuclear leucocytes without damaging phagocytes. 1995 J. Antimicrob. Chemother. pmid:8821593
Patton DL et al. The activity of azithromycin on the infectivity of Chlamydia trachomatis in human amniotic cells. 1995 J. Antimicrob. Chemother. pmid:8821594
Lane G Increased hypoprothrombinemic effect of warfarin possibly induced by azithromycin. 1996 Jul-Aug Ann Pharmacother pmid:8826581
Gerbaux C et al. Hyperactivity of cathepsin B and other lysosomal enzymes in fibroblasts exposed to azithromycin, a dicationic macrolide antibiotic with exceptional tissue accumulation. 1996 FEBS Lett. pmid:8830663
Domingo S and Gamazo C Inadequate azithromycin activity against Brucella melitensis in mice with acute or chronic infections. 1996 J Chemother pmid:8835110
Ehret JM et al. A clinical isolate of Neisseria gonorrhoeae with in vitro resistance to erythromycin and decreased susceptibility to azithromycin. 1996 Jul-Aug Sex Transm Dis pmid:8836018
Gnarpe J et al. In vitro activities of azithromycin and doxycycline against 15 isolates of Chlamydia pneumoniae. 1996 Antimicrob. Agents Chemother. pmid:8843291
Ednie LM et al. Comparative activities of clarithromycin, erythromycin, and azithromycin against penicillin-susceptible and penicillin-resistant pneumococci. 1996 Antimicrob. Agents Chemother. pmid:8843313
Bessette RE and Amsden GW Treatment of non-HIV cryptosporidial diarrhea with azithromycin. 1995 Ann Pharmacother pmid:8845560
Lo KK et al. An open non-comparative pilot study with azithromycin in the treatment of non-gonococcal urethritis in the sexually transmitted disease clinics in Hong Kong. 1995 Ann. Acad. Med. Singap. pmid:8849186
Pacifico L et al. Comparative efficacy and safety of 3-day azithromycin and 10-day penicillin V treatment of group A beta-hemolytic streptococcal pharyngitis in children. 1996 Antimicrob. Agents Chemother. pmid:8849215
Wondrack L et al. Clinical strain of Staphylococcus aureus inactivates and causes efflux of macrolides. 1996 Antimicrob. Agents Chemother. pmid:8849266
Amsden GW Erythromycin, clarithromycin, and azithromycin: are the differences real? 1996 Jan-Feb Clin Ther pmid:8851453
Jaruratanasirikul S et al. Distribution of azithromycin into brain tissue, cerebrospinal fluid, and aqueous humor of the eye. 1996 Antimicrob. Agents Chemother. pmid:8851625
Preac Mursic V et al. Kill kinetics of Borrelia burgdorferi and bacterial findings in relation to the treatment of Lyme borreliosis. 1996 Jan-Feb Infection pmid:8852456
Baradaran-Dilmaghani R and Stanek G In vitro susceptibility of thirty Borrelia strains from various sources against eight antimicrobial chemotherapeutics. 1996 Jan-Feb Infection pmid:8852472
Strle F et al. Azithromycin and doxycycline for treatment of Borrelia culture-positive erythema migrans. 1996 Jan-Feb Infection pmid:8852473
Gómez E et al. Interaction between azithromycin and cyclosporin? 1996 Nephron pmid:8856287
Burke SM Azithromycin: only once a day. 1996 May-Jun MCN Am J Matern Child Nurs pmid:8857402
Delmée M et al. In vitro susceptibilities of 180 clinical isolates of Haemophilus influenzae to ampicillin, amoxycillin/clavulanate, cefaclor, cefuroxime, cefotaxime, clarithromycin, and azithromycin. 1996 Acta Clin Belg pmid:8858889
Xu G et al. Effect of macrolide antibiotics on macrophage functions. 1996 Microbiol. Immunol. pmid:8865152
Vranes J et al. Influence of subinhibitory concentrations of ceftazidime, ciprofloxacin and azithromycin on the morphology and adherence of P-fimbriated escherichia coli. 1996 J Chemother pmid:8873829
Laing RB et al. Clinical features, outcome and survival from cerebral toxoplasmosis in Edinburgh AIDS patients. 1996 Int J STD AIDS pmid:8876356
Schaad UB and Heynen G Evaluation of the efficacy, safety and toleration of azithromycin vs. penicillin V in the treatment of acute streptococcal pharyngitis in children: results of a multicenter, open comparative study. The Swiss Tonsillopharyngitis Study Group. 1996 Pediatr. Infect. Dis. J. pmid:8878223
McLinn S and Williams D Incidence of antibiotic-resistant Streptococcus pneumoniae and beta-lactamase-positive Haemophilus influenzae in clinical isolates from patients with otitis media. 1996 Pediatr. Infect. Dis. J. pmid:8878239
McCarty J A multicenter, open label trial of azithromycin for the treatment of children with acute otitis media. 1996 Pediatr. Infect. Dis. J. pmid:8878240
Aronovitz G A multicenter, open label trial of azithromycin vs. amoxicillin/ clavulanate for the management of acute otitis media in children. 1996 Pediatr. Infect. Dis. J. pmid:8878241
McLinn S A multicenter, double blind comparison of azithromycin and amoxicillin/ clavulanate for the treatment of acute otitis media in children. 1996 Pediatr. Infect. Dis. J. pmid:8878242
Khurana CM A multicenter, randomized, open label comparison of azithromycin and amoxicillin/clavulanate in acute otitis media among children attending day care or school. 1996 Pediatr. Infect. Dis. J. pmid:8878243
Powers JL Properties of azithromycin that enhance the potential for compliance in children with upper respiratory tract infections. 1996 Pediatr. Infect. Dis. J. pmid:8878244
Wenisch C et al. Effect of single oral dose of azithromycin, clarithromycin, and roxithromycin on polymorphonuclear leukocyte function assessed ex vivo by flow cytometry. 1996 Antimicrob. Agents Chemother. pmid:8878577
Yeates RA et al. Interaction between midazolam and clarithromycin: comparison with azithromycin. 1996 Int J Clin Pharmacol Ther pmid:8880291
Dunn CJ and Barradell LB Azithromycin. A review of its pharmacological properties and use as 3-day therapy in respiratory tract infections. 1996 Drugs pmid:8882383
Watt B et al. Comparative activity of azithromycin against clinical isolates of mycobacteria. 1996 J. Antimicrob. Chemother. pmid:8889727
Tateda K et al. Direct evidence for antipseudomonal activity of macrolides: exposure-dependent bactericidal activity and inhibition of protein synthesis by erythromycin, clarithromycin, and azithromycin. 1996 Antimicrob. Agents Chemother. pmid:8891128
Patel KB et al. Comparison of bronchopulmonary pharmacokinetics of clarithromycin and azithromycin. 1996 Antimicrob. Agents Chemother. pmid:8891147
Hunt Gerardo S et al. Comparison of Etest to broth microdilution method for testing Streptococcus pneumoniae susceptibility to levofloxacin and three macrolides. 1996 Antimicrob. Agents Chemother. pmid:8891154
Wintermeyer SM et al. Dirithromycin: a new macrolide. 1996 Ann Pharmacother pmid:8893122
Biebuyck XA Comparison of azithromycin and co-amoxiclav in the treatment of acute tracheobronchitis and acute infectious exacerbations of chronic bronchitis in adults. Azithromycin Study Group. 1996 Sep-Oct J. Int. Med. Res. pmid:8895044
Three new studies expand understanding of MAC therapy. 1996 Am J Health Syst Pharm pmid:8899122