Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| [Antibiotics in routine practice. With proper selection rapid success]. | 2002 | MMW Fortschr Med | pmid:12532526 | |
| [Azithromycin for pediatric indications. Brief therapy is ideal for children]. | 2002 | MMW Fortschr Med | pmid:12532527 | |
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| Ivashkin VT et al. | Azithromycin in a triple therapy for H.pylori eradication in active duodenal ulcer. | 2002 | World J. Gastroenterol. | pmid:12378634 |
| Hook EW et al. | A randomized, comparative pilot study of azithromycin versus benzathine penicillin G for treatment of early syphilis. | 2002 | Sex Transm Dis | pmid:12172535 |
| Ohrt C et al. | Assessment of azithromycin in combination with other antimalarial drugs against Plasmodium falciparum in vitro. | 2002 | Antimicrob. Agents Chemother. | pmid:12121927 |
| Gandhi R et al. | Characterization of azithromycin hydrates. | 2002 | Eur J Pharm Sci | pmid:12128172 |
| Fulcher SF et al. | Delayed-onset mycobacterial keratitis after LASIK. | 2002 | Cornea | pmid:12131028 |
| Gaynor BD et al. | Rationale for mass antibiotic distribution for trachoma elimination. | 2002 | Int Ophthalmol Clin | pmid:12189619 |
| Fry AM et al. | Adverse and beneficial secondary effects of mass treatment with azithromycin to eliminate blindness due to trachoma in Nepal. | 2002 | Clin. Infect. Dis. | pmid:12145722 |
| Shelby-James TM et al. | Impact of single dose azithromycin on group A streptococci in the upper respiratory tract and skin of Aboriginal children. | 2002 | Pediatr. Infect. Dis. J. | pmid:12150171 |
| Davis JL et al. | Pharmacokinetics of azithromycin in foals after i.v. and oral dose and disposition into phagocytes. | 2002 | J. Vet. Pharmacol. Ther. | pmid:12000529 |
| Ng LK et al. | Mutation in 23S rRNA associated with macrolide resistance in Neisseria gonorrhoeae. | 2002 | Antimicrob. Agents Chemother. | pmid:12183262 |
| Mandell GL and Coleman EJ | Effect of antipyretic agents on uptake, transport, and release of antimicrobial agents by human polymorphonuclear leukocytes. | 2002 | J. Infect. Dis. | pmid:12001049 |
| Prunier AL et al. | Clinical isolates of Staphylococcus aureus with ribosomal mutations conferring resistance to macrolides. | 2002 | Antimicrob. Agents Chemother. | pmid:12183270 |
| Treadway G et al. | The safety of azithromycin in the treatment of adults with community-acquired respiratory tract infections. | 2002 | Int. J. Antimicrob. Agents | pmid:11932140 |
| [Unfortunately without effectiveness: chlamydia eradication after infarct]. | 2002 | MMW Fortschr Med | pmid:12014269 | |
| Suriawinata A and Min AD | A 33-year-old woman with jaundice after azithromycin use. | 2002 | Semin. Liver Dis. | pmid:12016551 |
| Evans AT et al. | Azithromycin for acute bronchitis: a randomised, double-blind, controlled trial. | 2002 | Lancet | pmid:12020525 |
| King A et al. | Erythromycin susceptibility of viridans streptococci from the normal throat flora of patients treated with azithromycin or clarithromycin. | 2002 | Clin. Microbiol. Infect. | pmid:11952721 |
| Kutlin A et al. | Effect of gemifloxacin on viability of Chlamydia pneumoniae (Chlamydophila pneumoniae) in an in vitro continuous infection model. | 2002 | J. Antimicrob. Chemother. | pmid:12003969 |
| Rustomjee R et al. | A randomized controlled trial of azithromycin versus doxycycline/ciprofloxacin for the syndromic management of sexually transmitted infections in a resource-poor setting. | 2002 | J. Antimicrob. Chemother. | pmid:12003988 |
| Voytilla KL et al. | Visual compatibility of azithromycin with 24 commonly used drugs during simulated Y-site delivery. | 2002 | Am J Health Syst Pharm | pmid:12004465 |
| Amsden GW et al. | A study of the interaction potential of azithromycin and clarithromycin with atorvastatin in healthy volunteers. | 2002 | J Clin Pharmacol | pmid:11936570 |
| Lacroix JS et al. | Symptoms and clinical and radiological signs predicting the presence of pathogenic bacteria in acute rhinosinusitis. | 2002 | Acta Otolaryngol. | pmid:11936912 |
| Ghaffar F et al. | Effects of large dosages of amoxicillin/clavulanate or azithromycin on nasopharyngeal carriage of Streptococcus pneumoniae, Haemophilus influenzae, nonpneumococcal alpha-hemolytic streptococci, and Staphylococcus aureus in children with acute otitis media. | 2002 | Clin. Infect. Dis. | pmid:11981724 |
| Edelstein PH | Predicting the emergence of antimicrobial resistance. | 2002 | Clin. Infect. Dis. | pmid:11981741 |
| Bosch-Driessen LH et al. | A prospective, randomized trial of pyrimethamine and azithromycin vs pyrimethamine and sulfadiazine for the treatment of ocular toxoplasmosis. | 2002 | Am. J. Ophthalmol. | pmid:12095805 |
| Champney WS and Miller M | Inhibition of 50S ribosomal subunit assembly in Haemophilus influenzae cells by azithromycin and erythromycin. | 2002 | Curr. Microbiol. | pmid:12000992 |
| Butler T | Reduction of MIC of azithromycin for Salmonella typhi and Staphylococcus aureus in broth exposed to previous growth of Salmonella typhi. | 2002 | J. Antimicrob. Chemother. | pmid:12096025 |
| White RL et al. | Comparative activity of gatifloxacin and other antibiotics against 4009 clinical isolates of Streptococcus pneumoniae in the United States during 1999-2000. | 2002 | Diagn. Microbiol. Infect. Dis. | pmid:12106954 |
| Jung R et al. | Intracellular activity of ABT-773 and other antimicrobial agents against Legionella pneumophila. | 2002 | J. Antimicrob. Chemother. | pmid:12003984 |
| Gaylor AS and Reilly JC | Therapy with macrolides in patients with cystic fibrosis. | 2002 | Pharmacotherapy | pmid:11837560 |
| Muirhead GJ et al. | The effects of steady-state erythromycin and azithromycin on the pharmacokinetics of sildenafil in healthy volunteers. | 2002 | Br J Clin Pharmacol | pmid:11879258 |
| Gomberg MA | [Combined treatment of persisting urogenital chlamydia infection with sumamed and interferon alfa]. | 2002 | Antibiot. Khimioter. | pmid:12365322 |
| Hammerschlag MR | Effect of azithromycin on endothelial function of patients with coronary artery disease and evidence of Chlamydia pneumoniae infection. | 2002 | Circulation | pmid:12370232 |
| Adimora AA | Treatment of uncomplicated genital Chlamydia trachomatis infections in adults. | 2002 | Clin. Infect. Dis. | pmid:12353204 |
| Augenbraun MH | Treatment of syphilis 2001: nonpregnant adults. | 2002 | Clin. Infect. Dis. | pmid:12353205 |
| Itoh M et al. | [A case of immotile-dyskinetic cilia syndrome responding to clenbuterol hydrochloride and azithromycin]. | 2002 | Nihon Kokyuki Gakkai Zasshi | pmid:12382429 |
| Equi A et al. | Long term azithromycin in children with cystic fibrosis: a randomised, placebo-controlled crossover trial. | 2002 | Lancet | pmid:12383667 |
| Ohara T et al. | Effects of azithromycin on shiga toxin production by Escherichia coli and subsequent host inflammatory response. | 2002 | Antimicrob. Agents Chemother. | pmid:12384353 |
| Sullivan B et al. | Comparison of azithromycin and clarithromycin in triple therapy regimens for the eradication of Helicobacter pylori. | 2002 | Am. J. Gastroenterol. | pmid:12385435 |
| Brook I | Antibacterial therapy for acute group a streptococcal pharyngotonsillitis: short-course versus traditional 10-day oral regimens. | 2002 | Paediatr Drugs | pmid:12390046 |
| Tambiah J and Powell JT | Chlamydia pneumoniae antigens facilitate experimental aortic dilatation: prevention with azithromycin. | 2002 | J. Vasc. Surg. | pmid:12422113 |
| Arnez M et al. | Solitary erythema migrans in children: comparison of treatment with azithromycin and phenoxymethylpenicillin. | 2002 | Wien. Klin. Wochenschr. | pmid:12422590 |
| Maraspin V et al. | Development of erythema migrans in spite of treatment with antibiotics after a tick bite. | 2002 | Wien. Klin. Wochenschr. | pmid:12422612 |
| Hall IH et al. | Disposition and intracellular activity of azithromycin in human THP-1 acute monocytes. | 2002 | Int. J. Antimicrob. Agents | pmid:12431870 |
| Wolter JM et al. | Macrolides in cystic fibrosis: is there a role? | 2002 | Am J Respir Med | pmid:14720043 |
| Nagai K et al. | Susceptibility to telithromycin in 1,011 Streptococcus pyogenes isolates from 10 central and Eastern European countries. | 2002 | Antimicrob. Agents Chemother. | pmid:11796375 |
| Vorbach H et al. | Endothelial cell compatibility of azithromycin and erythromycin. | 2002 | J. Antimicrob. Chemother. | pmid:11815590 |
| Krudsood S et al. | A comparative clinical trial of combinations of dihydroartemisinin plus azithromycin and dihydroartemisinin plus mefloquine for treatment of multidrug resistant falciparum malaria. | 2002 | Southeast Asian J. Trop. Med. Public Health | pmid:12693587 |
| Burton MJ et al. | Azithromycin for the treatment and control of trachoma. | 2002 | Expert Opin Pharmacother | pmid:11829725 |
| Ohara T et al. | [Protective effect of azithromycin against verotoxin]. | 2002 | Kansenshogaku Zasshi | pmid:11905000 |
| Salaria M and Singh M | Atypical pneumonia in children. | 2002 | Indian Pediatr | pmid:11910135 |
| Desta Z et al. | In vitro inhibition of pimozide N-dealkylation by selective serotonin reuptake inhibitors and azithromycin. | 2002 | J Clin Psychopharmacol | pmid:11910261 |
| Ito N and Kudo S | [Case of polycystic lung disease with mixed infections due to Aspergillus and Mycobacterium fortuitum successfully treated by AZM]. | 2002 | Jpn J Antibiot | pmid:12664928 |
| Kim MK et al. | Bactericidal effect and pharmacodynamics of cethromycin (ABT-773) in a murine pneumococcal pneumonia model. | 2002 | Antimicrob. Agents Chemother. | pmid:12234843 |
| Smith SR et al. | A double-blind placebo-controlled trial of azithromycin as an adjunct to non-surgical treatment of periodontitis in adults: clinical results. | 2002 | J. Clin. Periodontol. | pmid:11846850 |
| Milberg P et al. | Divergent proarrhythmic potential of macrolide antibiotics despite similar QT prolongation: fast phase 3 repolarization prevents early afterdepolarizations and torsade de pointes. | 2002 | J. Pharmacol. Exp. Ther. | pmid:12235254 |
| Wu ML et al. | Enterocolonic Mycobacterium avium-intracellulare. | 2002 | Arch. Pathol. Lab. Med. | pmid:11860323 |
| Cascio A and Colomba C | [Macrolides in the treatment of children with Mediterranean spotted fever]. | 2002 | Infez Med | pmid:12704264 |
| Parchure N et al. | Effect of azithromycin treatment on endothelial function in patients with coronary artery disease and evidence of Chlamydia pneumoniae infection. | 2002 | Circulation | pmid:11901039 |
| SoRelle R | Treatment with azithromycin improves endothelial function. | 2002 | Circulation | pmid:11902195 |
| Firsov AA et al. | Comparative pharmacodynamics of azithromycin and roxithromycin with S. pyogenes and S. pneumoniae in a model that simulates in vitro pharmacokinetics in human tonsils. | 2002 | J. Antimicrob. Chemother. | pmid:11751774 |
| Zubata P et al. | A new HPLC method for azithromycin quantitation. | 2002 | J Pharm Biomed Anal | pmid:11814725 |
| Lentino JR and Krasnicka B | Association between initial empirical therapy and decreased length of stay among veteran patients hospitalized with community acquired pneumonia. | 2002 | Int. J. Antimicrob. Agents | pmid:11814769 |
| Phillips P et al. | Azithromycin prophylaxis for Mycobacterium avium complex during the era of highly active antiretroviral therapy: evaluation of a provincial program. | 2002 | Clin. Infect. Dis. | pmid:11774085 |
| Lau CY and Qureshi AK | Azithromycin versus doxycycline for genital chlamydial infections: a meta-analysis of randomized clinical trials. | 2002 | Sex Transm Dis | pmid:12218839 |
| Culić O et al. | Azithromycin modulates neutrophil function and circulating inflammatory mediators in healthy human subjects. | 2002 | Eur. J. Pharmacol. | pmid:12208321 |
| Silva FM et al. | Low efficacy of an ultra-short term, once-daily dose triple therapy with omeprazole, azithromycin, and secnidazole for Helicobacter pylori eradication in peptic ulcer. | 2002 Jan-Feb | Rev Hosp Clin Fac Med Sao Paulo | pmid:12170343 |
| Kadappu KK et al. | Azithromycin as treatment for cryptosporidiosis in human immunodeficiency virus disease. | 2002 Jul-Sep | J Postgrad Med | pmid:12432190 |
| Yaqubi GH and Anani GR | Prevalence of trachoma in chronic conjunctivitis, Birjand, Islamic Republic of Iran. | 2002 Mar-May | East. Mediterr. Health J. | pmid:15339124 |
| Basilion EV et al. | Height as a proxy for weight in determining azithromycin treatment for paediatric trachoma. | 2002 Nov-Dec | Trans. R. Soc. Trop. Med. Hyg. | pmid:12625152 |
| Mileusnic D et al. | Pathological case of the month: sudden death in a child as a result of pancreatitis during valproic acid therapy. | 2002 Sep-Oct | Pediatr Pathol Mol Med | pmid:12396903 |
| Mesa FL et al. | Antibiotic treatment of incipient drug-induced gingival overgrowth in adult renal transplant patients. | 2003 | J. Periodont. Res. | pmid:12608908 |
| [Uncomplicated community-acquired pneumonia. Under control in 3 treatment days]. | 2003 | MMW Fortschr Med | pmid:12619240 | |
| Arreaza L et al. | Emergence of gonococcal strains with resistance to azithromycin in Spain. | 2003 | J. Antimicrob. Chemother. | pmid:12493814 |
| Adachi JA et al. | Azithromycin found to be comparable to levofloxacin for the treatment of US travelers with acute diarrhea acquired in Mexico. | 2003 | Clin. Infect. Dis. | pmid:14557959 |
| Schriever C et al. | Red wine, resveratrol, Chlamydia pneumoniae and the French connection. | 2003 | Atherosclerosis | pmid:14644410 |
| Jennings MB et al. | Comparison of azithromycin and cefadroxil for the treatment of uncomplicated skin and skin structure infections. | 2003 | Cutis | pmid:14533837 |
| Callaghan R and Allen M | Mycobacterium malmoense infection of the knee. | 2003 | Ann. Rheum. Dis. | pmid:14583565 |
| Niederman MS | [Conservative use of antibiotics is important, but: "Resistance hysteria is exaggerated"]. | 2003 | MMW Fortschr Med | pmid:14584217 |
| Al-Belasy FA and Hairam AR | The efficacy of azithromycin in the treatment of acute infraorbital space infection. | 2003 | J. Oral Maxillofac. Surg. | pmid:12618970 |
| Dunne MW et al. | Randomized, double-blind study of the clinical efficacy of 3 days of azithromycin compared with co-amoxiclav for the treatment of acute otitis media. | 2003 | J. Antimicrob. Chemother. | pmid:12888586 |
| Rush C and Simon MW | The effect of amoxicillin-clavulanate, cefixime and azithromycin on normal throat flora in children with group A streptococcal pharyngitis. | 2003 | Clin Pediatr (Phila) | pmid:12862350 |
| Lildholdt T et al. | The natural history of recurrent acute tonsillitis and a clinical trial of azithromycin for antibiotic prophylaxis. | 2003 | Clin Otolaryngol Allied Sci | pmid:12871256 |
| Crum NF et al. | Halting a pneumococcal pneumonia outbreak among United States Marine Corps trainees. | 2003 | Am J Prev Med | pmid:12880877 |
| Bhattacharya MK et al. | Azithromycin in the treatment of cholera in children. | 2003 | Acta Paediatr. | pmid:12856976 |
| Favre-Bonté S et al. | Biofilm formation by Pseudomonas aeruginosa: role of the C4-HSL cell-to-cell signal and inhibition by azithromycin. | 2003 | J. Antimicrob. Chemother. | pmid:12951348 |
| Carryn S et al. | Activity of beta-lactams (ampicillin, meropenem), gentamicin, azithromycin and moxifloxacin against intracellular Listeria monocytogenes in a 24 h THP-1 human macrophage model. | 2003 | J. Antimicrob. Chemother. | pmid:12654747 |
| Danesi R et al. | Comparative distribution of azithromycin in lung tissue of patients given oral daily doses of 500 and 1000 mg. | 2003 | J. Antimicrob. Chemother. | pmid:12654753 |
| Zhanel GG et al. | Pharmacodynamic activity of azithromycin against macrolide-susceptible and -resistant Streptococcus pneumoniae simulating clinically achievable free serum, epithelial lining fluid and middle ear fluid concentrations. | 2003 | J. Antimicrob. Chemother. | pmid:12775677 |
| Blandford JM and Gift TL | The cost-effectiveness of single-dose azithromycin for treatment of incubating syphilis. | 2003 | Sex Transm Dis | pmid:12782951 |
| Abdelghaffar H et al. | Interaction of macrolides and ketolides with the phagocytic cell line PLB-985. | 2003 | J Chemother | pmid:12962363 |
| Castaldo RS et al. | A comparison of 5-day courses of dirithromycin and azithromycin in the treatment of acute exacerbations of chronic obstructive pulmonary disease. | 2003 | Clin Ther | pmid:12749513 |
| Skerk V et al. | Comparative analysis of azithromycin and ciprofloxacin in the treatment of chronic prostatitis caused by Chlamydia trachomatis. | 2003 | Int. J. Antimicrob. Agents | pmid:12727080 |
| Trad O et al. | Eradication of Cryptosporidium in four children with acute lymphoblastic leukemia. | 2003 | J. Trop. Pediatr. | pmid:12729299 |
| Zhou WQ et al. | [Clinic efficacy of treating chronic prostatitis caused by Neisseria gonorrhoeae with azithromycin aspartic-acid injection]. | 2003 | Zhonghua Nan Ke Xue | pmid:12680331 |
| Sicklinger M et al. | In vitro susceptibility testing of four antibiotics against Borrelia burgdorferi: a comparison of results for the three genospecies Borrelia afzelii, Borrelia garinii, and Borrelia burgdorferi sensu stricto. | 2003 | J. Clin. Microbiol. | pmid:12682190 |
| Ioannidis J and Wilkinson D | HIV: prevention of opportunistic infections. | 2003 | Clin Evid | pmid:15555123 |