Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Jones RN et al. | Validation of NCCLS macrolide (azithromycin, clarithromycin, and erythromycin) interpretive criteria for Haemophilus influenzae tested with the Haemophilus test medium. National Committee for Clinical Laboratory Standards. | 1994 | Diagn. Microbiol. Infect. Dis. | pmid:7924221 |
Wallace MR et al. | Azithromycin and typhoid. | 1994 | Lancet | pmid:7911192 |
Pacor ML et al. | [Safety of azithromycin in patients allergic to penicillin and cephalosporin]. | 1994 | Clin Ter | pmid:8001336 |
Wolinsky E | Mycobacterium avium strains resistant to clarithromycin and azithromycin. | 1994 | Antimicrob. Agents Chemother. | pmid:8031406 |
Trevisi P et al. | Toxic pustuloderma associated with azithromycin. | 1994 | Clin. Exp. Dermatol. | pmid:8033402 |
Katelaris PH et al. | Activity of metronidazole, azithromycin and three benzimidazoles on Giardia lamblia growth and attachment to a human intestinal cell line. | 1994 | Aliment. Pharmacol. Ther. | pmid:8038350 |
Steven N et al. | Corticosteroid therapy for AIDS patients with Mycobacterium avium-intracellulare infection. | 1994 | AIDS | pmid:8011231 |
Chiarini F et al. | Chlamydia trachomatis genitourinary infections: laboratory diagnosis and therapeutic aspects. Evaluation of in vitro and in vivo effectiveness of azithromycin. | 1994 | J Chemother | pmid:7830100 |
Wang JH et al. | Azithromycin in the treatment of pneumonia caused by Chlamydia pneumoniae: report of a case. | 1994 | J. Formos. Med. Assoc. | pmid:7866068 |
[Newly approved specialty drugs in Austria and new knowledge about currently available specialty drugs. Zithromax capsules, dried syrup]. | 1994 | Wien. Klin. Wochenschr. | pmid:7975673 | |
Cynamon MH et al. | Comparative activities of azithromycin and clarithromycin against Mycobacterium avium infection in beige mice. | 1994 | Antimicrob. Agents Chemother. | pmid:7979270 |
Klemens SP and Cynamon MH | Activities of azithromycin and clarithromycin against nontuberculous mycobacteria in beige mice. | 1994 | Antimicrob. Agents Chemother. | pmid:7979271 |
Schönwald S et al. | Three-day azithromycin compared with ten-day roxithromycin treatment of atypical pneumonia. | 1994 | Scand. J. Infect. Dis. | pmid:7747094 |
Bush MR and Rosa C | Azithromycin and erythromycin in the treatment of cervical chlamydial infection during pregnancy. | 1994 | Obstet Gynecol | pmid:8008325 |
Godofsky EW | Treatment of presumed cerebral toxoplasmosis with azithromycin. | 1994 | N. Engl. J. Med. | pmid:8302335 |
Kelsey JJ et al. | Presence of azithromycin breast milk concentrations: a case report. | 1994 | Am. J. Obstet. Gynecol. | pmid:8178871 |
Rapp RP et al. | New macrolide antibiotics: usefulness in infections caused by mycobacteria other than Mycobacterium tuberculosis. | 1994 | Ann Pharmacother | pmid:7849341 |
Goldman MP and Longworth DL | The role of azithromycin and clarithromycin in clinical practice. | 1993 Sep-Oct | Cleve Clin J Med | pmid:8403355 |
Weber K et al. | Azithromycin versus penicillin V for the treatment of early Lyme borreliosis. | 1993 Nov-Dec | Infection | pmid:8132365 |
Scaglione F et al. | A new model examining intracellular and extracellular activity of amoxicillin, azithromycin, and clarithromycin in infected cells. | 1993 Nov-Dec | Chemotherapy | pmid:8222870 |