Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Crohn Disease D003424 12 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Sinusitis D012852 9 associated lipids
Immunologic Deficiency Syndromes D007153 8 associated lipids
Penile Diseases D010409 2 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Psoriasis D011565 47 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Cross Infection D003428 9 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Per page 10 20 50 100 | Total 276

PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Chimura T [Changes of antibody titers during antimicrobial therapy including levofloxacin for Chlamydia infections in the obstetrics and gynecology field]. 2002 Jpn J Antibiot pmid:12071097
Cohen R et al. Comparison of two dosages of azithromycin for three days versus penicillin V for ten days in acute group A streptococcal tonsillopharyngitis. 2002 Pediatr. Infect. Dis. J. pmid:12075760
Schaad UB et al. Azithromycin versus penicillin V for treatment of acute group A streptococcal pharyngitis. 2002 Pediatr. Infect. Dis. J. pmid:12075761
Domeika M et al. Chlamydia trachomatis infections in eastern Europe: legal aspects, epidemiology, diagnosis, and treatment. 2002 Sex Transm Infect pmid:12081171
Patrick DM et al. Heterosexual outbreak of infectious syphilis: epidemiological and ethnographic analysis and implications for control. 2002 Sex Transm Infect pmid:12083438
Reshetniak VI et al. [Eradication of Helicobacter pylori in patients with duodenal ulcer following the short course of treatment with azitromycin and amoxycillin]. 2002 Antibiot. Khimioter. pmid:12087718
Kays MB et al. Azithromycin treatment failure in community-acquired pneumonia caused by Streptococcus pneumoniae resistant to macrolides by a 23S rRNA mutation. 2002 Diagn. Microbiol. Infect. Dis. pmid:12088625
Breier AR et al. Microbiological assay for azithromycin in pharmaceutical formulations. 2002 J Pharm Biomed Anal pmid:12093530
Bosch-Driessen LH et al. A prospective, randomized trial of pyrimethamine and azithromycin vs pyrimethamine and sulfadiazine for the treatment of ocular toxoplasmosis. 2002 Am. J. Ophthalmol. pmid:12095805
Butler T Reduction of MIC of azithromycin for Salmonella typhi and Staphylococcus aureus in broth exposed to previous growth of Salmonella typhi. 2002 J. Antimicrob. Chemother. pmid:12096025
White RL et al. Comparative activity of gatifloxacin and other antibiotics against 4009 clinical isolates of Streptococcus pneumoniae in the United States during 1999-2000. 2002 Diagn. Microbiol. Infect. Dis. pmid:12106954
Matute AJ et al. Double-blind, placebo-controlled study comparing the effect of azithromycin with clarithromycin on oropharyngeal and bowel microflora in volunteers. 2002 Eur. J. Clin. Microbiol. Infect. Dis. pmid:12111597
Williams ES and Miller JM Results from late-breaking clinical trial sessions at the American College of Cardiology 51st Annual Scientific Session. 2002 J. Am. Coll. Cardiol. pmid:12113263
Ohrt C et al. Assessment of azithromycin in combination with other antimalarial drugs against Plasmodium falciparum in vitro. 2002 Antimicrob. Agents Chemother. pmid:12121927
Gandhi R et al. Characterization of azithromycin hydrates. 2002 Eur J Pharm Sci pmid:12128172
Fulcher SF et al. Delayed-onset mycobacterial keratitis after LASIK. 2002 Cornea pmid:12131028
Infection fighters. MAC prevention takes a holiday. 2000 TreatmentUpdate pmid:12132450
House D et al. Cytokine release by lipopolysaccharide-stimulated whole blood from patients with typhoid fever. 2002 J. Infect. Dis. pmid:12134261
Wallace Jr RJ et al. Repeat positive cultures in Mycobacterium intracellulare lung disease after macrolide therapy represent new infections in patients with nodular bronchiectasis. 2002 J. Infect. Dis. pmid:12134265
Fry AM et al. Adverse and beneficial secondary effects of mass treatment with azithromycin to eliminate blindness due to trachoma in Nepal. 2002 Clin. Infect. Dis. pmid:12145722
Shelby-James TM et al. Impact of single dose azithromycin on group A streptococci in the upper respiratory tract and skin of Aboriginal children. 2002 Pediatr. Infect. Dis. J. pmid:12150171
Weiss LM Babesiosis in humans: a treatment review. 2002 Expert Opin Pharmacother pmid:12150690
Blondeau JM The evolution and role of macrolides in infectious diseases. 2002 Expert Opin Pharmacother pmid:12150692
Cheng H et al. Synthesis and SAR of azalide 3,6-ketal aromatic derivatives as potent Gram-positive and Gram-negative antibacterial agents. 2002 Bioorg. Med. Chem. Lett. pmid:12161150
Silva FM et al. Low efficacy of an ultra-short term, once-daily dose triple therapy with omeprazole, azithromycin, and secnidazole for Helicobacter pylori eradication in peptic ulcer. 2002 Jan-Feb Rev Hosp Clin Fac Med Sao Paulo pmid:12170343
Hook EW et al. A randomized, comparative pilot study of azithromycin versus benzathine penicillin G for treatment of early syphilis. 2002 Sex Transm Dis pmid:12172535
Kawashima M et al. Inhibitory effects of 14-membered ring macrolide antibiotics on bleomycin-induced acute lung injury. 2002 Lung pmid:12182159
Yee CL et al. Tendon or joint disorders in children after treatment with fluoroquinolones or azithromycin. 2002 Pediatr. Infect. Dis. J. pmid:12182376
Clark C et al. In vitro selection of resistance in Haemophilus influenzae by amoxicillin-clavulanate, cefpodoxime, cefprozil, azithromycin, and clarithromycin. 2002 Antimicrob. Agents Chemother. pmid:12183253
Ng LK et al. Mutation in 23S rRNA associated with macrolide resistance in Neisseria gonorrhoeae. 2002 Antimicrob. Agents Chemother. pmid:12183262
Prunier AL et al. Clinical isolates of Staphylococcus aureus with ribosomal mutations conferring resistance to macrolides. 2002 Antimicrob. Agents Chemother. pmid:12183270
Gaynor BD et al. Rationale for mass antibiotic distribution for trachoma elimination. 2002 Int Ophthalmol Clin pmid:12189619
Maizumi N et al. Quantitative comparison of the cytocidal effect of seven macrolide antibiotics on human periodontal ligament fibroblasts. 2002 J. Periodont. Res. pmid:12200967
Kopjar B Azithromycin is effective in patients with chronic bronchitis. 2002 J. Antimicrob. Chemother. pmid:12205072
Baschiera F et al. Improved tonsillar disposition of azithromycin following a 3-day oral treatment with 20 mg kg(-1) in paediatric patients. 2002 Pharmacol. Res. pmid:12208127
Culić O et al. Azithromycin modulates neutrophil function and circulating inflammatory mediators in healthy human subjects. 2002 Eur. J. Pharmacol. pmid:12208321
Stone AF et al. Effect of treatment for Chlamydia pneumoniae and Helicobacter pylori on markers of inflammation and cardiac events in patients with acute coronary syndromes: South Thames Trial of Antibiotics in Myocardial Infarction and Unstable Angina (STAMINA). 2002 Circulation pmid:12208796
Sirois F [Delirium associated with azithromycin administration]. 2002 Can J Psychiatry pmid:12211892
Lau CY and Qureshi AK Azithromycin versus doxycycline for genital chlamydial infections: a meta-analysis of randomized clinical trials. 2002 Sex Transm Dis pmid:12218839
Sieper J and Braun J [Diagnosis and antibiotic treatment of reactive arthritis]. 2002 Dtsch. Med. Wochenschr. pmid:12226789
Fraser-Hurt N and Mabey D Trachoma. 2002 Clin Evid pmid:12230687
Kim MK et al. Bactericidal effect and pharmacodynamics of cethromycin (ABT-773) in a murine pneumococcal pneumonia model. 2002 Antimicrob. Agents Chemother. pmid:12234843
Milberg P et al. Divergent proarrhythmic potential of macrolide antibiotics despite similar QT prolongation: fast phase 3 repolarization prevents early afterdepolarizations and torsade de pointes. 2002 J. Pharmacol. Exp. Ther. pmid:12235254
Frank E et al. A multicenter, open-label, randomized comparison of levofloxacin and azithromycin plus ceftriaxone in hospitalized adults with moderate to severe community-acquired pneumonia. 2002 Clin Ther pmid:12240780
Rao RU et al. Brugia malayi: effects of antibacterial agents on larval viability and development in vitro. 2002 Exp. Parasitol. pmid:12243742
Adimora AA Treatment of uncomplicated genital Chlamydia trachomatis infections in adults. 2002 Clin. Infect. Dis. pmid:12353204
Augenbraun MH Treatment of syphilis 2001: nonpregnant adults. 2002 Clin. Infect. Dis. pmid:12353205
Steinberg JM and Srugo I Reoccurrence of culture-positive pertussis in an infant initially treated with azithromycin and steroids. 2002 Arch Pediatr Adolesc Med pmid:12361458
Gomberg MA [Combined treatment of persisting urogenital chlamydia infection with sumamed and interferon alfa]. 2002 Antibiot. Khimioter. pmid:12365322
Hammerschlag MR Effect of azithromycin on endothelial function of patients with coronary artery disease and evidence of Chlamydia pneumoniae infection. 2002 Circulation pmid:12370232