Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Crohn Disease D003424 12 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Sinusitis D012852 9 associated lipids
Immunologic Deficiency Syndromes D007153 8 associated lipids
Penile Diseases D010409 2 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Psoriasis D011565 47 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Cross Infection D003428 9 associated lipids
Pseudomonas Infections D011552 25 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Bharat V and Mohanty B Bleeding complication during coumarin therapy due to amiodarone and azithromycin. 2000 J Assoc Physicians India pmid:11273517
Gulati R et al. Comparative bioavailability of two formulations of azithromycin. 2000 J Assoc Physicians India pmid:11273540
Parsad D et al. Azithromycin monthly pulse vs daily doxycycline in the treatment of acne vulgaris. 2001 J. Dermatol. pmid:11280457
Waring AL et al. Development of a genomics-based PCR assay for detection of Mycoplasma pneumoniae in a large outbreak in New York State. 2001 J. Clin. Microbiol. pmid:11283060
Holm SO et al. Comparison of two azithromycin distribution strategies for controlling trachoma in Nepal. 2001 Bull. World Health Organ. pmid:11285662
Frick KD et al. Cost-effectiveness of trachoma control measures: comparing targeted household treatment and mass treatment of children. 2001 Bull. World Health Organ. pmid:11285663
Bailey R and Lietman T The SAFE strategy for the elimination of trachoma by 2020: will it work? 2001 Bull. World Health Organ. pmid:11285668
Sorvillo F et al. Incidence and determinants of Pseudomonas aeruginosa infection among persons with HIV: association with hospital exposure. 2001 Am J Infect Control pmid:11287873
Treadway G Azithromycin: a new 15-membered macrolide. 2001 Jpn J Antibiot pmid:11296412
Hafner R et al. Tolerance and pharmacokinetic interactions of rifabutin and azithromycin. 2001 Antimicrob. Agents Chemother. pmid:11302832
Powell FC What's going on in rosacea? 2000 J Eur Acad Dermatol Venereol pmid:11305376
Elewski BE A novel treatment for acne vulgaris and rosacea. 2000 J Eur Acad Dermatol Venereol pmid:11305392
Lechner A and Bruckner DA Oligella ureolytica in blood culture: contaminant or infection? 2001 Eur. J. Clin. Microbiol. Infect. Dis. pmid:11305472
Jacobson JM et al. Dose-escalation, phase I/II study of azithromycin and pyrimethamine for the treatment of toxoplasmic encephalitis in AIDS. 2001 AIDS pmid:11316995
Kays MB and Denys GA In vitro activity and pharmacodynamics of azithromycin and clarithromycin against Streptococcus pneumoniae based on serum and intrapulmonary pharmacokinetics. 2001 Clin Ther pmid:11318076
Gupta S et al. Pharmacokinetic and safety profile of desloratadine and fexofenadine when coadministered with azithromycin: a randomized, placebo-controlled, parallel-group study. 2001 Clin Ther pmid:11318079
Zarantonelli L et al. Decreased susceptibility to azithromycin and erythromycin mediated by a novel mtr(R) promoter mutation in Neisseria gonorrhoeae. 2001 J. Antimicrob. Chemother. pmid:11328778
Skerk V et al. Duration of clinical symptoms in female patients with acute urethral syndrome caused by Chlamydia trachomatis treated with azithromycin or doxycycline. 2001 J Chemother pmid:11330365
Rodríguez Núñez A et al. [Chemoprophylaxis of meningococcal disease with azithromycin and ciprofloxacin]. 2001 An. Esp. Pediatr. pmid:11333489
Samra Z et al. In vitro susceptibility of recent clinical isolates of Chlamydia trachomatis to macrolides and tetracyclines. 2001 Diagn. Microbiol. Infect. Dis. pmid:11337185