Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Crohn Disease D003424 12 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Sinusitis D012852 9 associated lipids
Immunologic Deficiency Syndromes D007153 8 associated lipids
Penile Diseases D010409 2 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Psoriasis D011565 47 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Cross Infection D003428 9 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Per page 10 20 50 100 | Total 276

PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Grunden JW and Fisher KA Lovastatin-induced rhabdomyolysis possibly associated with clarithromycin and azithromycin. 1997 Jul-Aug Ann Pharmacother pmid:9220046
Luke DR and Foulds G Toleration of intravenous azithromycin. 1997 Ann Pharmacother pmid:9296232
Fraser LA et al. Calcium channel blocker-clarithromycin drug interaction did not increase the risk of nonvertebral fracture: a population-based study. 2015 Ann Pharmacother pmid:25429094
Ballow CH and Amsden GW Azithromycin: the first azalide antibiotic. 1992 Ann Pharmacother pmid:1330097
Rao KB et al. Enhanced hypoprothrombinemia with warfarin due to azithromycin. 2004 Ann Pharmacother pmid:15084685
Thompson DF and Ramos CL Antibiotic-Induced Rash in Patients With Infectious Mononucleosis. 2017 Ann Pharmacother pmid:27620494
Howard PA Azithromycin-induced proarrhythmia and cardiovascular death. 2013 Ann Pharmacother pmid:24285766
Amsden GW Macrolides versus azalides: a drug interaction update. 1995 Ann Pharmacother pmid:8547740
Woldtvedt BR et al. Possible increased anticoagulation effect of warfarin induced by azithromycin. 1998 Ann Pharmacother pmid:9496419
Potter TG and Snider KR Azithromycin for the treatment of gastroparesis. 2013 Ann Pharmacother pmid:23447477
Burgess DS et al. A time-kill evaluation of clarithromycin and azithromycin against two extracellular pathogens and the development of resistance. 1999 Ann Pharmacother pmid:10630825
Rapp RP Pharmacokinetics and pharmacodynamics of intravenous and oral azithromycin: enhanced tissue activity and minimal drug interactions. 1998 Jul-Aug Ann Pharmacother pmid:9681095
Zaremba CD Comment: could acetaminophen have played a role in a possible azithromycin-warfarin interaction? 1998 Jul-Aug Ann Pharmacother pmid:9681108
Hatton RC and Harbilas JW Comment: Azithromycin for gastroparesis. 2013 Ann Pharmacother pmid:23613098
Therriault BL et al. Severe sepsis caused by Arcanobacterium haemolyticum: a case report and review of the literature. 2008 Ann Pharmacother pmid:18812563
Davis TM Adverse effects of antimalarial prophylactic drugs: an important consideration in the risk-benefit equation. 1998 Ann Pharmacother pmid:9793605
Rapp RP et al. New macrolide antibiotics: usefulness in infections caused by mycobacteria other than Mycobacterium tuberculosis. 1994 Ann Pharmacother pmid:7849341
Lane G Increased hypoprothrombinemic effect of warfarin possibly induced by azithromycin. 1996 Jul-Aug Ann Pharmacother pmid:8826581
Bessette RE and Amsden GW Treatment of non-HIV cryptosporidial diarrhea with azithromycin. 1995 Ann Pharmacother pmid:8845560
Riesselman A and El-Mallakh RS Akathisia with azithromycin. 2015 Ann Pharmacother pmid:25870444