Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Crohn Disease D003424 12 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Sinusitis D012852 9 associated lipids
Immunologic Deficiency Syndromes D007153 8 associated lipids
Penile Diseases D010409 2 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Psoriasis D011565 47 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Cross Infection D003428 9 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Per page 10 20 50 100 | Total 276

PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Karhu E et al. Identification of Privileged Antichlamydial Natural Products by a Ligand-Based Strategy. 2017 J. Nat. Prod. pmid:29043803
Tuite AR et al. Impact of Rapid Susceptibility Testing and Antibiotic Selection Strategy on the Emergence and Spread of Antibiotic Resistance in Gonorrhea. 2017 J. Infect. Dis. pmid:28968710
González-Beiras C et al. Single-Dose Azithromycin for the Treatment of Haemophilus ducreyi Skin Ulcers in Papua New Guinea. 2017 Clin. Infect. Dis. pmid:29020192
Trembizki E et al. High levels of macrolide-resistant Mycoplasma genitalium in Queensland, Australia. 2017 J. Med. Microbiol. pmid:28893363
Lu Y et al. Antibiotics Promote Escherichia coli-Pseudomonas aeruginosa Conjugation through Inhibiting Quorum Sensing. 2017 Antimicrob. Agents Chemother. pmid:28993333
Agarwal P et al. susceptibility of Indian isolates to different antimalarial drugs & antibiotics. 2017 Indian J. Med. Res. pmid:29512604
Savaris RF et al. Antibiotic therapy for pelvic inflammatory disease. 2017 Cochrane Database Syst Rev pmid:28436019
Snelling PJ et al. Rhabdomyolysis Complicating Typhoid Fever in A Child and Review of the Literature. 2017 Pediatr. Infect. Dis. J. pmid:28430751
Koštrun S et al. Around the macrolide - Impact of 3D structure of macrocycles on lipophilicity and cellular accumulation. 2017 Eur J Med Chem pmid:28410508
Yang Z et al. Azithromycin Causes a Novel Proarrhythmic Syndrome. 2017 Circ Arrhythm Electrophysiol pmid:28408648
Doan T et al. Gut Microbial Diversity in Antibiotic-Naive Children After Systemic Antibiotic Exposure: A Randomized Controlled Trial. 2017 Clin. Infect. Dis. pmid:28402408
Husein-ElAhmed H Single nontender ulcer on the glans. 2017 J Fam Pract pmid:28375399
Leeyaphan C et al. Treatment Outcomes for Rectal Lymphogranuloma Venereum in Men Who Have Sex with Men Using Doxycycline, Azithromycin, or Both: A Review of Clinical Cases. 2017 Sex Transm Dis pmid:28282652
Rasmussen LD et al. Follicular bronchiolitis in an HIV-infected individual on combination antiretroviral therapy with low CD4+ cell count but sustained viral suppression. 2017 BMJ Case Rep pmid:29191821
Ito S et al. Haemophilus influenzae Isolated From Men With Acute Urethritis: Its Pathogenic Roles, Responses to Antimicrobial Chemotherapies, and Antimicrobial Susceptibilities. 2017 Sex Transm Dis pmid:28282645
Stieler Stewart AL et al. Effects of clarithromycin, azithromycin and rifampicin on terbutaline-induced sweating in foals. 2017 Equine Vet. J. pmid:28238211
Emmanuel R et al. Antimicrobial efficacy of drug blended biosynthesized colloidal gold nanoparticles from Justicia glauca against oral pathogens: A nanoantibiotic approach. 2017 Microb. Pathog. pmid:29101061
Allan RN et al. Cephalosporin-NO-donor prodrug PYRRO-C3D shows β-lactam-mediated activity against Streptococcus pneumoniae biofilms. 2017 Nitric Oxide pmid:28235635
Riddle MS et al. Trial Evaluating Ambulatory Therapy of Travelers' Diarrhea (TrEAT TD) Study: A Randomized Controlled Trial Comparing 3 Single-Dose Antibiotic Regimens With Loperamide. 2017 Clin. Infect. Dis. pmid:29029033
Alchakaki A et al. Which patients with respiratory disease need long-term azithromycin? 2017 Cleve Clin J Med pmid:28985171
Senilă S et al. Infliximab-induced acne and acute localized exanthematous pustulosis: Case report. 2017 Dermatol Ther pmid:28976720
Koeva M et al. An Antipersister Strategy for Treatment of Chronic Pseudomonas aeruginosa Infections. 2017 Antimicrob. Agents Chemother. pmid:28923873
Ito A et al. A Case of Community-Acquired Pneumonia Due to Legionella pneumophila Serogroup 9 Wherein Initial Treatment with Single-Dose Oral Azithromycin Appeared Useful. 2017 Jpn. J. Infect. Dis. pmid:28890505
Cluver C et al. Interventions for treating genital Chlamydia trachomatis infection in pregnancy. 2017 Cochrane Database Syst Rev pmid:28937705
Mandhane PJ et al. Treatment of preschool children presenting to the emergency department with wheeze with azithromycin: A placebo-controlled randomized trial. 2017 PLoS ONE pmid:28771627
Gifford J et al. Decision support during electronic prescription to stem antibiotic overuse for acute respiratory infections: a long-term, quasi-experimental study. 2017 BMC Infect. Dis. pmid:28760143
Upadhyay K et al. Combination therapy with ampicillin and azithromycin improved outcomes in a mouse model of group B streptococcal sepsis. 2017 PLoS ONE pmid:28759625
Greig JR and Jones L Adjunctive Azithromycin Prophylaxis for Cesarean Delivery. 2017 N. Engl. J. Med. pmid:28079334
Li R et al. Effects of oral florfenicol and azithromycin on gut microbiota and adipogenesis in mice. 2017 PLoS ONE pmid:28742883
Bellon H et al. Interleukin-1α induced release of interleukin-8 by human bronchial epithelial cells in vitro: assessing mechanisms and possible treatment options. 2017 Transpl. Int. pmid:28078769
Li Y et al. Synergistic Activity of Berberine with Azithromycin against Pseudomonas Aeruginosa Isolated from Patients with Cystic Fibrosis of Lung In Vitro and In Vivo. 2017 Cell. Physiol. Biochem. pmid:28738346
Llop CJ et al. Antibiotic treatment patterns, costs, and resource utilization among patients with community acquired pneumonia: a US cohort study. 2017 Hosp Pract (1995) pmid:28064542
West SK et al. Treating village newcomers and travelers for trachoma: Results from ASANTE cluster randomized trial. 2017 PLoS ONE pmid:28662043
Johnson SR et al. Use of whole-genome sequencing data to analyze 23S rRNA-mediated azithromycin resistance. 2017 Int. J. Antimicrob. Agents pmid:28038960
Sanders AM et al. Burden of trachoma in five counties of Eastern Equatoria state, South Sudan: Results from population-based surveys. 2017 PLoS Negl Trop Dis pmid:28614375
Allen G Evidence appraisal of Tita ATN, Szychowski JM, Boggess K, et al. Adjunctive azithromycin prophylaxis for cesarean delivery.: N Engl J Med. 2016;375:1231-1241. 2017 AORN J pmid:28034388
Jiang FX et al. Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from Hefei (2014-2015): genetic characteristics of antimicrobial resistance. 2017 BMC Infect. Dis. pmid:28545411
Park J et al. Progression and Treatment Outcomes of Lung Disease Caused by Mycobacterium abscessus and Mycobacterium massiliense. 2017 Clin. Infect. Dis. pmid:28011609
Karalius VP et al. Bordetella parapertussis outbreak in Southeastern Minnesota and the United States, 2014. 2017 Medicine (Baltimore) pmid:28514288
Read TR et al. Azithromycin 1.5g Over 5 Days Compared to 1g Single Dose in Urethral Mycoplasma genitalium: Impact on Treatment Outcome and Resistance. 2017 Clin. Infect. Dis. pmid:28011607
Vodstrcil LA et al. Measurement of tissue azithromycin levels in self-collected vaginal swabs post treatment using liquid chromatography and tandem mass spectrometry (LC-MS/MS). 2017 PLoS ONE pmid:28498845
Schwameis M et al. Topical azithromycin for the prevention of Lyme borreliosis: a randomised, placebo-controlled, phase 3 efficacy trial. 2017 Lancet Infect Dis pmid:28007428
Houinei W et al. Haemophilus ducreyi DNA is detectable on the skin of asymptomatic children, flies and fomites in villages of Papua New Guinea. 2017 PLoS Negl Trop Dis pmid:28489855
Nenoff P et al. [Non-viral sexually transmitted infections - Epidemiology, clinical manifestations, diagnostics and therapy : Part 1: Gonococci]. 2017 Hautarzt pmid:27981386
Rutenberg D et al. Efficacy of Tulathromycin for the Treatment of Foals with Mild to Moderate Bronchopneumonia. 2017 J. Vet. Intern. Med. pmid:28421633
White AC Treatment of Early Syphilis in HIV: What Do We Really Know? 2017 Clin. Infect. Dis. pmid:28362951
Trifirò G et al. Use of azithromycin and risk of ventricular arrhythmia. 2017 CMAJ pmid:28420680
Amza A et al. A Cluster-Randomized Trial to Assess the Efficacy of Targeting Trachoma Treatment to Children. 2017 Clin. Infect. Dis. pmid:27956455
Sharpton R et al. Do cystic fibrosis patients on azithromycin need electrocardiogram monitoring? 2017 Pulm Pharmacol Ther pmid:28219728
Braam JF et al. High prevalence of the A2058T macrolide resistance-associated mutation in Mycoplasma genitalium strains from the Netherlands. 2017 J. Antimicrob. Chemother. pmid:28158595
Pavlova A et al. Toward the rational design of macrolide antibiotics to combat resistance. 2017 Chem Biol Drug Des pmid:28419786
Gensel JC et al. Predictive screening of M1 and M2 macrophages reveals the immunomodulatory effectiveness of post spinal cord injury azithromycin treatment. 2017 Sci Rep pmid:28057928
Szczepanska B et al. Prevalence and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli isolated from children and environmental sources in urban and suburban areas. 2017 BMC Microbiol. pmid:28376713
Seyama S et al. Amino Acid Substitution in the Major Multidrug Efflux Transporter Protein AcrB Contributes to Low Susceptibility to Azithromycin in Haemophilus influenzae. 2017 Antimicrob. Agents Chemother. pmid:28848006
Sutton SS Is cardiovascular risk a concern when prescribing azithromycin? 2017 JAAPA pmid:28033168
Yoon HY et al. Clinical significance of QT-prolonging drug use in patients with MDR-TB or NTM disease. 2017 Int. J. Tuberc. Lung Dis. pmid:28826448
Shapiro ED and Wormser GP Prophylaxis with topical azithromycin against Lyme borreliosis. 2017 Lancet Infect Dis pmid:28007427
Whiley DM et al. Molecular Antimicrobial Resistance Surveillance for Neisseria gonorrhoeae, Northern Territory, Australia. 2017 Emerging Infect. Dis. pmid:28820128
Seyama S et al. Emergence and molecular characterization of Haemophilus influenzae harbouring mef(A). 2017 J. Antimicrob. Chemother. pmid:27999037
Fage C et al. The combination of oseltamivir with azithromycin does not show additional benefits over oseltamivir monotherapy in mice infected with influenza A(H1N1)pdm2009 virus. 2017 J. Med. Virol. pmid:28792077
Koetsveld J et al. Susceptibility of the Relapsing-Fever Spirochete Borrelia miyamotoi to Antimicrobial Agents. 2017 Antimicrob. Agents Chemother. pmid:28674060
Kawamura K et al. Azithromycin for idiopathic acute exacerbation of idiopathic pulmonary fibrosis: a retrospective single-center study. 2017 BMC Pulm Med pmid:28629448
Nozawa H et al. Pertussis without apparent cough in a disabled girl with a tracheostomy. 2017 J. Infect. Chemother. pmid:28623110
Chavada VD et al. Surface plasmon resonance based selective and sensitive colorimetric determination of azithromycin using unmodified silver nanoparticles in pharmaceuticals and human plasma. 2017 Spectrochim Acta A Mol Biomol Spectrosc pmid:27419643
Tsubouchi K et al. Azithromycin attenuates myofibroblast differentiation and lung fibrosis development through proteasomal degradation of NOX4. 2017 Autophagy pmid:28613983
Smith KS et al. Biological and Behavioral Factors Associated With Positive Chlamydia Retests. 2017 Sex Transm Dis pmid:28608791
Wind CM et al. Decreased Azithromycin Susceptibility of Neisseria gonorrhoeae Isolates in Patients Recently Treated with Azithromycin. 2017 Clin. Infect. Dis. pmid:28510723
van Wagensveld L et al. [Persistent, therapy-resistant conjunctivitis: consider infection with Chlamydia trachomatis]. 2017 Ned Tijdschr Geneeskd pmid:28443807
Foerster S et al. A new rapid resazurin-based microdilution assay for antimicrobial susceptibility testing of Neisseria gonorrhoeae. 2017 J. Antimicrob. Chemother. pmid:28431096
Bouklouze A et al. Azithromycin assay in drug formulations: Validation of a HPTLC method with a quadratic polynomial calibration model using the accuracy profile approach. 2017 Ann Pharm Fr pmid:27692351
Collins SA et al. Cephalosporin-3'-Diazeniumdiolate NO Donor Prodrug PYRRO-C3D Enhances Azithromycin Susceptibility of Nontypeable Haemophilus influenzae Biofilms. 2017 Antimicrob. Agents Chemother. pmid:27919896
Manesh A et al. A case of clinical and microbiological failure of azithromycin therapy in Salmonella enterica serotype Typhi despite low azithromycin MIC. 2017 Int. J. Infect. Dis. pmid:27894983
Zhang Y et al. Novel Detection Strategy To Rapidly Evaluate the Efficacy of Antichlamydial Agents. 2017 Antimicrob. Agents Chemother. pmid:27855081
Waites KB et al. In Vitro Activities of Lefamulin and Other Antimicrobial Agents against Macrolide-Susceptible and Macrolide-Resistant Mycoplasma pneumoniae from the United States, Europe, and China. 2017 Antimicrob. Agents Chemother. pmid:27855075
Thompson DF and Ramos CL Antibiotic-Induced Rash in Patients With Infectious Mononucleosis. 2017 Ann Pharmacother pmid:27620494
Rajesh AM and Popat KM Taste masking of azithromycin by resin complex and sustained release through interpenetrating polymer network with functionalized biopolymers. 2017 Drug Dev Ind Pharm pmid:27600608
Jakubů V et al. Trends in the Minimum Inhibitory Concentrations of Erythromycin, Clarithromycin, Azithromycin, Ciprofloxacin, and Trimethoprim/Sulfamethoxazole for Strains of Bordetella pertussis isolated in the Czech Republic in 1967-2015. 2017 Cent. Eur. J. Public Health pmid:29346850
Romero L et al. Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults. 2017 Cochrane Database Syst Rev pmid:29226307
Dror T et al. Microbiota manipulation for weight change. 2017 Microb. Pathog. pmid:26792677
Han B et al. Intrahepatic cholestasis of pregnancy or azithromycin-induced intrahepatic cholestasis: A case report. 2017 Medicine (Baltimore) pmid:29384912
Burr SE et al. Does azithromycin given to women in labour decrease ocular bacterial infection in neonates? A double-blind, randomized trial. 2017 BMC Infect. Dis. pmid:29282015
Atkinson CT et al. Expression of acquired macrolide resistance genes in Haemophilus influenzae. 2017 J. Antimicrob. Chemother. pmid:28961896
Allen GP and Harris KA Resistance Selection in Shigella flexneri by Azithromycin, Ceftriaxone, Ciprofloxacin, Levofloxacin, and Moxifloxacin. 2017 Antimicrob. Agents Chemother. pmid:28483960
Waetzig V et al. Neurodegenerative effects of azithromycin in differentiated PC12 cells. 2017 Eur. J. Pharmacol. pmid:28479141
Park HS et al. Subantibiotic dose of azithromycin attenuates alveolar bone destruction and improves trabecular microarchitectures in a rat model of experimental periodontitis: A study using micro-computed tomography. 2017 Int. Immunopharmacol. pmid:28432937
Menzel M et al. Azithromycin augments rhinovirus-induced IFNβ via cytosolic MDA5 in experimental models of asthma exacerbation. 2017 Oncotarget pmid:28415826
Kneidinger N et al. Lung volumes predict survival in patients with chronic lung allograft dysfunction. 2017 Eur. Respir. J. pmid:28404648
Venekamp RP and Schilder AGM Clinical failure is more common in young children with acute otitis media who receive a short course of antibiotics compared with standard duration. 2017 Evid Based Med pmid:28404603
Ma Q et al. A Waterborne Outbreak of Shigella sonnei with Resistance to Azithromycin and Third-Generation Cephalosporins in China in 2015. 2017 Antimicrob. Agents Chemother. pmid:28373192
Wind CM et al. A Case-Control Study of Molecular Epidemiology in Relation to Azithromycin Resistance in Neisseria gonorrhoeae Isolates Collected in Amsterdam, the Netherlands, between 2008 and 2015. 2017 Antimicrob. Agents Chemother. pmid:28373191
Watson JR et al. Healthcare Claims Data: An Underutilized Tool for Pediatric Outpatient Antimicrobial Stewardship. 2017 Clin. Infect. Dis. pmid:28329388
Thompson CN et al. Treatment Response in Enteric Fever in an Era of Increasing Antimicrobial Resistance: An Individual Patient Data Analysis of 2092 Participants Enrolled into 4 Randomized, Controlled Trials in Nepal. 2017 Clin. Infect. Dis. pmid:28329181
Emerging risk of untreatable gonorrhea and what to do about it. 2017 Can Fam Physician pmid:28292798
Fohner AE et al. PharmGKB summary: Macrolide antibiotic pathway, pharmacokinetics/pharmacodynamics. 2017 Pharmacogenet. Genomics pmid:28146011
Horner P and Saunders J Should azithromycin 1 g be abandoned as a treatment for bacterial STIs? The case for and against. 2017 Sex Transm Infect pmid:27418572
Bergeron A et al. Azithromycin and Survival After Hematopoietic Stem Cell Transplant-Reply. 2017 JAMA pmid:29279924
Fuji S Azithromycin and Survival After Hematopoietic Stem Cell Transplant. 2017 JAMA pmid:29279920
Castelli G et al. PURLs: Does azithromycin have a role in cesarean sections? 2017 J Fam Pract pmid:29202146
Skeith AE et al. Adding Azithromycin to Cephalosporin for Cesarean Delivery Infection Prophylaxis: A Cost-Effectiveness Analysis. 2017 Obstet Gynecol pmid:29112658
Stanbrook MB Azithromycin reduced exacerbations and improved QoL in symptomatic asthma despite inhaled maintenance therapy. 2017 Ann. Intern. Med. pmid:29049761