Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Dyspnea D004417 10 associated lipids
Ectodermal Dysplasia D004476 1 associated lipids
Edema D004487 152 associated lipids
Eisenmenger Complex D004541 1 associated lipids
Elephantiasis D004604 2 associated lipids
Elephantiasis, Filarial D004605 4 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Enteritis D004751 8 associated lipids
Epiglottitis D004826 1 associated lipids
Erythema Nodosum D004893 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

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What genes are associated with Azithramycine?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
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Garey KW et al. Lack of effect of zafirlukast on the pharmacokinetics of azithromycin, clarithromycin, and 14-hydroxyclarithromycin in healthy volunteers. 1999 Antimicrob. Agents Chemother. pmid:10223928
Ouadrhiri Y et al. Mechanism of the intracellular killing and modulation of antibiotic susceptibility of Listeria monocytogenes in THP-1 macrophages activated by gamma interferon. 1999 Antimicrob. Agents Chemother. pmid:10223943
Könönen E et al. beta-lactamase production and antimicrobial susceptibility of oral heterogeneous Fusobacterium nucleatum populations in young children. 1999 Antimicrob. Agents Chemother. pmid:10223950
Ogasawara KK and Goodwin TM Efficacy of azithromycin in reducing lower genital Ureaplasma urealyticum colonization in women at risk for preterm delivery. 1999 Jan-Feb J Matern Fetal Med pmid:10052839
Klapan I et al. Azithromycin versus amoxicillin/clavulanate in the treatment of acute sinusitis. 1999 Jan-Feb Am J Otolaryngol pmid:9950107
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Dagan R et al. Bacteriologic efficacies of oral azithromycin and oral cefaclor in treatment of acute otitis media in infants and young children. 2000 Antimicrob. Agents Chemother. pmid:10602721
Infection fighters. MAC prevention takes a holiday. 2000 TreatmentUpdate pmid:12132450
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Fernandez-Obregon AC Azithromycin for the treatment of acne. 2000 Int. J. Dermatol. pmid:10651967
Laming AC et al. A targeted, single-dose azithromycin strategy for trachoma. 2000 Med. J. Aust. pmid:10772587
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Tsitsika A et al. Single-oral-dose azithromycin prophylaxis against experimental streptococcal or staphylococcal aortic valve endocarditis. 2000 Antimicrob. Agents Chemother. pmid:10817749
Bin XX et al. Effect of azithromycin plus rifampin versus amoxicillin alone on eradication and inflammation in the chronic course of Chlamydia pneumoniae pneumonitis in mice. 2000 Antimicrob. Agents Chemother. pmid:10817751
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Chinh NT et al. A randomized controlled comparison of azithromycin and ofloxacin for treatment of multidrug-resistant or nalidixic acid-resistant enteric fever. 2000 Antimicrob. Agents Chemother. pmid:10858343
Miltner EC and Bermudez LE Mycobacterium avium grown in Acanthamoeba castellanii is protected from the effects of antimicrobials. 2000 Antimicrob. Agents Chemother. pmid:10858369
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Nishi Y et al. [Effect of macrolide antibiotics on adhesion by cancer cells]. 2000 Jpn J Antibiot pmid:10756450
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Giacometti A et al. Anticryptosporidial activity of ranalexin, lasalocid and azithromycin alone and in combination in cell lines. 2000 J. Antimicrob. Chemother. pmid:10702561
Hammerschlag MR Treatment of Chlamydia pneumoniae. 2000 Int. J. Antimicrob. Agents pmid:10926449
Slavinsky J et al. Factors associated with the decline in sexually transmitted infections among HIV-positive women. 2000 J. Acquir. Immune Defic. Syndr. pmid:10708065
Angelilli ML et al. Palatability of oral antibiotics among children in an urban primary care center. 2000 Arch Pediatr Adolesc Med pmid:10710025
González de Aledo Linos A and García Merino J [Control of a school outbreak of serogroup B meningococcal disease by chemoprophylaxis with azithromycin and ciprofloxacin]. 2000 An. Esp. Pediatr. pmid:11521657
Dagan R et al. Bacteriologic and clinical efficacy of amoxicillin/clavulanate vs. azithromycin in acute otitis media. 2000 Pediatr. Infect. Dis. J. pmid:10693993
Gómez J et al. [Prospective, comparative study (1994-1998) of the influence of short-term prophylactic treatment with azithromycin on patients with advanced COPD]. 2000 Rev Esp Quimioter pmid:11498704
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Arata J [Azithromycin in the field of dermatology]. 2000 Jpn J Antibiot pmid:12572094
Sasaki J [Azithromycin in dentistry and oral surgery]. 2000 Jpn J Antibiot pmid:12572095
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Bharat V and Mohanty B Bleeding complication during coumarin therapy due to amiodarone and azithromycin. 2000 J Assoc Physicians India pmid:11273517
Gulati R et al. Comparative bioavailability of two formulations of azithromycin. 2000 J Assoc Physicians India pmid:11273540
Powell FC What's going on in rosacea? 2000 J Eur Acad Dermatol Venereol pmid:11305376
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