Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Wound Infection D014946 12 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Nephritis, Interstitial D009395 10 associated lipids
Peptic Ulcer D010437 19 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Birth Weight D001724 23 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Chavada VD et al. Surface plasmon resonance based selective and sensitive colorimetric determination of azithromycin using unmodified silver nanoparticles in pharmaceuticals and human plasma. 2017 Spectrochim Acta A Mol Biomol Spectrosc pmid:27419643
Tan X et al. Study on the chemiluminescence behavior of bovine serum albumin with luminol and its analytical application. 2011 Spectrochim Acta A Mol Biomol Spectrosc pmid:21435942
Ashour S and Bayram R Novel spectrophotometric method for determination of some macrolide antibiotics in pharmaceutical formulations using 1,2-naphthoquinone-4-sulphonate. 2012 Spectrochim Acta A Mol Biomol Spectrosc pmid:23041925
Schouten JT and Whittemore S Recent development in the treatment and prevention of disseminated Mycobacterium avium complex (MAC). 1996 STEP Perspect pmid:11364267
Schlünzen F et al. Structural basis for the antibiotic activity of ketolides and azalides. 2003 Structure pmid:12623020
Hassan KS and Al-Khadouri G Pneumonia with Worsening Pleural Effusion Despite Treatment with Appropriate Antimicrobials: Case report. 2018 Sultan Qaboos Univ Med J pmid:30210860
Semel ME et al. Babesiosis in the immediate postoperative period after splenectomy for trauma. 2009 Surg Infect (Larchmt) pmid:19622029
Cone LA et al. Delirium in the elderly resulting from azithromycin therapy. 2003 Surg Neurol pmid:12826358
Peng JY et al. Electrochemical behavior of azithromycin at graphene and ionic liquid composite film modified electrode. 2011 Talanta pmid:22063535
Luo Q et al. Surface plasmon resonance sensor for antibiotics detection based on photo-initiated polymerization molecularly imprinted array. 2016 Talanta pmid:27769483
Williams K Patient-delivered therapy: an additional means for addressing the Chlamydia trachomatis problem. 2002 Tenn Med pmid:12491815
Karpov OI et al. [Comparative trial of 3-day azithromycin versus 10-day coamoxilav course efficacy in acute sinusitis]. 1998 Ter. Arkh. pmid:9644751
MashkilleÄ­son AL [The treatment of early syphilis today]. 1996 Ter. Arkh. pmid:9045378
Khamitov RF et al. [Significance of antibacterial therapy of Chlamydophila pneumoniae infection in patients with bronchial asthma]. 2004 Ter. Arkh. pmid:15575487
Gage TW New drugs from 1991-1992. 1993 Tex Dent J pmid:8273018
Coeman M et al. Neomacrolides in the treatment of patients with severe asthma and/or bronchiectasis: a retrospective observational study. 2011 Ther Adv Respir Dis pmid:21890536
Wilms EB et al. Pharmacokinetics of azithromycin in plasma, blood, polymorphonuclear neutrophils and sputum during long-term therapy in patients with cystic fibrosis. 2006 Ther Drug Monit pmid:16628134
Fouda HG and Schneider RP Quantitative determination of the antibiotic azithromycin in human serum by high-performance liquid chromatography (HPLC)-atmospheric pressure chemical ionization mass spectrometry: correlation with a standard HPLC-electrochemical method. 1995 Ther Drug Monit pmid:7624907
Raines DA et al. Simultaneous high-performance liquid chromatography analysis of azithromycin and two of its metabolites in human tears and plasma. 1998 Ther Drug Monit pmid:9853988
le Normand Y et al. [Software modeling for better understanding of pharmacokinetic-pharmacodynamic relationships: application to azithromycin in the treatment of streptococcal tonsillitis and in acute exacerbation fo chronic bronchitis]]. 2004 Jan-Feb Therapie pmid:15199685