Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Wound Infection D014946 12 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Nephritis, Interstitial D009395 10 associated lipids
Peptic Ulcer D010437 19 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Birth Weight D001724 23 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Kerani RP et al. Gonorrhea treatment practices in the STD Surveillance Network, 2010-2012. 2015 Sex Transm Dis pmid:25504294
Handsfield HH et al. Multicenter trial of single-dose azithromycin vs. ceftriaxone in the treatment of uncomplicated gonorrhea. Azithromycin Gonorrhea Study Group. 1994 Mar-Apr Sex Transm Dis pmid:9071422
Yasin RM et al. Comparison of E-test with agar dilution methods in testing susceptibility of N. gonorrhoeae to azithromycin. 1997 Sex Transm Dis pmid:9153733
Okah E et al. Sentinel Surveillance for Expedited Partner Therapy Prescriptions Using Pharmacy Data, in 2 New York City Neighborhoods, 2015. 2017 Sex Transm Dis pmid:28079746
Beyda RM et al. Azithromycin efficacy in the treatment of Chlamydia trachomatis among detained youth. 2014 Sex Transm Dis pmid:25211253
Batteiger BE Azithromycin Efficacy in Asymptomatic Rectal Chlamydial Infection in Men Who Have Sex With Men: A More Definitive Answer Soon? 2017 Sex Transm Dis pmid:28604482
Zhou P et al. Azithromycin treatment failure among primary and secondary syphilis patients in Shanghai. 2010 Sex Transm Dis pmid:20644500
Lechtenberg RJ et al. Variation in adherence to the treatment guidelines for Neisseria gonorrhoeae by clinical practice setting, California, 2009 to 2011. 2014 Sex Transm Dis pmid:24722391
Carlin EM and Barton SE Azithromycin as a cost-effective treatment for nongonococcal urethritis in men. 1997 Sex Transm Dis pmid:9018784
Schumacher CM and Ghanem KG Retreatment rates for uncomplicated gonorrhea infection: comparing ceftriaxone and azithromycin versus ceftriaxone and doxycycline. 2013 Sex Transm Dis pmid:23965767
Abdolrasouli A and Roushan A Corynebacterium propinquum associated with acute, nongonococcal urethritis. 2013 Sex Transm Dis pmid:24275738
Rahangdale L et al. An observational cohort study of Chlamydia trachomatis treatment in pregnancy. 2006 Sex Transm Dis pmid:16432482
Levy V et al. A Case of Persistent and Possibly Treatment Resistant Pharyngeal Gonorrhea. 2016 Sex Transm Dis pmid:26967304
Mmeje O and Coleman JS Concurrent patient-partner treatment in pregnancy: an alternative to expedited partner therapy? 2012 Sex Transm Dis pmid:22902661
Barberá MJ et al. Mycoplasma genitalium Macrolide and Fluoroquinolone Resistance: Prevalence and Risk Factors Among a 2013-2014 Cohort of Patients in Barcelona, Spain. 2017 Sex Transm Dis pmid:28703723
Hillis SD et al. Doxycycline and azithromycin for prevention of chlamydial persistence or recurrence one month after treatment in women. A use-effectiveness study in public health settings. 1998 Sex Transm Dis pmid:9437777
Llata E et al. Management of Pelvic Inflammatory Disease in Selected U.S. Sexually Transmitted Disease Clinics: Sexually Transmitted Disease Surveillance Network, January 2010-December 2011. 2015 Sex Transm Dis pmid:26165434
Tabidze IL et al. Adherence to Centers for Disease Control and Prevention Gonococcal Treatment Guidelines Among Chicago Health Care Providers, 2011-2012. 2015 Sex Transm Dis pmid:26165433
Stamm WE et al. A randomized, double-blind study comparing single-dose rifalazil with single-dose azithromycin for the empirical treatment of nongonococcal urethritis in men. 2007 Sex Transm Dis pmid:17297383
Herchline TE and Inkrott BP Resistance trends in Neisseria gonorrhoeae in southwestern Ohio. 2010 Sex Transm Dis pmid:19901861
Gose SO et al. Failure of azithromycin 2.0 g in the treatment of gonococcal urethritis caused by high-level resistance in California. 2015 Sex Transm Dis pmid:25868141
Van Damme K et al. Evaluation of azithromycin resistance in Treponema pallidum specimens from Madagascar. 2009 Sex Transm Dis pmid:19901863
Weinstein SA and Stiles BG A review of the epidemiology, diagnosis and evidence-based management of Mycoplasma genitalium. 2011 Sex Health pmid:21592428
McCormick DF et al. Prevention and control of sexually transmissible infections among hotel-based female sex workers in Dhaka, Bangladesh. 2013 Sex Health pmid:24262217
Robertson A et al. Case report: lymphogranuloma venereum in New Zealand. 2008 Sex Health pmid:19061558
Stratov I et al. Azithromycin: more lethal than chloramphenicol? 2013 Sex Health pmid:23448962
Renault CA et al. Time to clearance of Chlamydia trachomatis ribosomal RNA in women treated for chlamydial infection. 2011 Sex Health pmid:21371385
Jones S et al. The tip of the iceberg: opportunistic screening for Chlamydia trachomatis in asymptomatic patients attending a young people's health clinic reveals a high prevalence--a pilot study. 2004 Sex Health pmid:16334993
Suriawinata A and Min AD A 33-year-old woman with jaundice after azithromycin use. 2002 Semin. Liver Dis. pmid:12016551
Pedro-Botet ML and Sabrià M Legionellosis. 2005 Semin Respir Crit Care Med pmid:16388431
Berger BW Lyme disease. 1993 Semin Dermatol pmid:8312152
Seguí Díaz M [What is the best treatment for urogenital Chlamydia trachomatis infection?] Semergen pmid:27068255
Wawer MJ et al. AIDS intervention in Uganda. 1995 Science pmid:7570005
Topp E et al. Reduced persistence of the macrolide antibiotics erythromycin, clarithromycin and azithromycin in agricultural soil following several years of exposure in the field. 2016 Sci. Total Environ. pmid:27096634
Sidhu H et al. Risk assessment of biosolids-borne ciprofloxacin and azithromycin. 2019 Sci. Total Environ. pmid:30463165
Sidhu H et al. Plant toxicity and accumulation of biosolids-borne ciprofloxacin and azithromycin. 2019 Sci. Total Environ. pmid:30340267
Sidhu H et al. Retention-release of ciprofloxacin and azithromycin in biosolids and biosolids-amended soils. 2019 Sci. Total Environ. pmid:30196217
Sidhu H et al. Bioavailability of biosolids-borne ciprofloxacin and azithromycin to terrestrial organisms: Microbial toxicity and earthworm responses. 2019 Sci. Total Environ. pmid:30195128
Friesen J et al. Natural immunization against malaria: causal prophylaxis with antibiotics. 2010 Sci Transl Med pmid:20630856
Ratzinger F et al. Azithromycin suppresses CD4(+) T-cell activation by direct modulation of mTOR activity. 2014 Sci Rep pmid:25500904
Gensel JC et al. Predictive screening of M1 and M2 macrophages reveals the immunomodulatory effectiveness of post spinal cord injury azithromycin treatment. 2017 Sci Rep pmid:28057928
Wang A et al. Effects of Fluoroquinolones and Azithromycin on Biofilm Formation of Stenotrophomonas maltophilia. 2016 Sci Rep pmid:27405358
Menzel M et al. Azithromycin induces anti-viral effects in cultured bronchial epithelial cells from COPD patients. 2016 Sci Rep pmid:27350308
Zeng J et al. Mechanism of azithromycin inhibition of HSL synthesis in Pseudomonas aeruginosa. 2016 Sci Rep pmid:27075730
Pansieri C et al. Ureaplasma, bronchopulmonary dysplasia, and azithromycin in European neonatal intensive care units: a survey. 2014 Sci Rep pmid:24518104
Das MC et al. Attenuation of Pseudomonas aeruginosa biofilm formation by Vitexin: A combinatorial study with azithromycin and gentamicin. 2016 Sci Rep pmid:27000525
Gualdoni GA et al. Azithromycin inhibits IL-1 secretion and non-canonical inflammasome activation. 2015 Sci Rep pmid:26152605
Feary DJ et al. Lawsonia intracellularis proliferative enteropathy in a foal. 2007 Schweiz. Arch. Tierheilkd. pmid:17410971
Dickerson FB et al. A double-blind trial of adjunctive azithromycin in individuals with schizophrenia who are seropositive for Toxoplasma gondii. 2009 Schizophr. Res. pmid:19464853
Brihmer C et al. Efficacy and safety of azithromycin versus lymecyline in the treatment of genital chlamydial infections in women. 1996 Scand. J. Infect. Dis. pmid:8953672