| MeSH term | MeSH ID | Detail |
|---|---|---|
| Wound Infection | D014946 | 12 associated lipids |
| Respiratory Insufficiency | D012131 | 10 associated lipids |
| Gram-Negative Bacterial Infections | D016905 | 16 associated lipids |
| Hyperbilirubinemia | D006932 | 11 associated lipids |
| Nephritis, Interstitial | D009395 | 10 associated lipids |
| Peptic Ulcer | D010437 | 19 associated lipids |
| Cat-Scratch Disease | D002372 | 4 associated lipids |
| Birth Weight | D001724 | 23 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Cytomegalovirus Infections | D003586 | 7 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Suskova VS et al. | [Immuno-modulating properties of a macrolide antibiotic "Z-factor"]. | 2003 | Antibiot. Khimioter. | pmid:15002174 |
| Pisarev VV et al. | [Comparative study of azithromycin pharmacokinetics in healthy volunteers in open cross randomized procedure]. | 2003 | Antibiot. Khimioter. | pmid:15004973 |
| Bogdanov MB and Chernen'kaia TV | [Microbiological evaluation of antibiotics for empirical therapy of community-acquired infections of the lower respiratory tract]. | 2000 | Antibiot. Khimioter. | pmid:11212394 |
| Budanov SV | [Azithromycin (sumamed)--basic properties and therapy of community-acquired pneumonia]. | 2000 | Antibiot. Khimioter. | pmid:11212397 |
| Iur'ev SIu et al. | [Azithromycin levels in the chorion tissue within the first three months of the pregnancy term]. | 2004 | Antibiot. Khimioter. | pmid:15850052 |
| Parry CM et al. | Randomized controlled comparison of ofloxacin, azithromycin, and an ofloxacin-azithromycin combination for treatment of multidrug-resistant and nalidixic acid-resistant typhoid fever. | 2007 | Antimicrob. Agents Chemother. | pmid:17145784 |
| Matlow A et al. | Susceptibilities of neonatal respiratory isolates of Ureaplasma urealyticum to antimicrobial agents. | 1998 | Antimicrob. Agents Chemother. | pmid:9593171 |
| Donowitz GR and Earnhardt KI | Azithromycin inhibition of intracellular Legionella micdadei. | 1993 | Antimicrob. Agents Chemother. | pmid:8285604 |
| Strickman D et al. | In vitro effectiveness of azithromycin against doxycycline-resistant and -susceptible strains of Rickettsia tsutsugamushi, etiologic agent of scrub typhus. | 1995 | Antimicrob. Agents Chemother. | pmid:8585717 |
| Bermudez LE et al. | Stimulation with cytokines enhances penetration of azithromycin into human macrophages. | 1991 | Antimicrob. Agents Chemother. | pmid:1667256 |
| Rodvold KA et al. | Steady-state plasma and bronchopulmonary concentrations of intravenous levofloxacin and azithromycin in healthy adults. | 2003 | Antimicrob. Agents Chemother. | pmid:12878504 |
| Dunne MW et al. | Efficacy of single-dose azithromycin in treatment of acute otitis media in children after a baseline tympanocentesis. | 2003 | Antimicrob. Agents Chemother. | pmid:12878537 |
| Mulet X et al. | Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants. | 2009 | Antimicrob. Agents Chemother. | pmid:19188376 |
| Conte JE et al. | Single-dose intrapulmonary pharmacokinetics of azithromycin, clarithromycin, ciprofloxacin, and cefuroxime in volunteer subjects. | 1996 | Antimicrob. Agents Chemother. | pmid:8807050 |
| Nash KA and Inderlied CB | Rapid detection of mutations associated with macrolide resistance in Mycobacterium avium complex. | 1996 | Antimicrob. Agents Chemother. | pmid:8807078 |
| Neoh CF et al. | Rapid and sensitive liquid chromatography/mass spectrometry assay for caspofungin in human aqueous humor. | 2010 | Antimicrob. Agents Chemother. | pmid:20660672 |
| Zhanel GG et al. | Mutant prevention concentrations of levofloxacin alone and in combination with azithromycin, ceftazidime, colistin (Polymyxin E), meropenem, piperacillin-tazobactam, and tobramycin against Pseudomonas aeruginosa. | 2006 | Antimicrob. Agents Chemother. | pmid:16723591 |
| Girgis NI et al. | Azithromycin versus ciprofloxacin for treatment of uncomplicated typhoid fever in a randomized trial in Egypt that included patients with multidrug resistance. | 1999 | Antimicrob. Agents Chemother. | pmid:10348767 |
| Wolf K and Malinverni R | Effect of azithromycin plus rifampin versus that of azithromycin alone on the eradication of Chlamydia pneumoniae from lung tissue in experimental pneumonitis. | 1999 | Antimicrob. Agents Chemother. | pmid:10348778 |
| Ngo LY et al. | Pharmacokinetics of azithromycin administered alone and with atovaquone in human immunodeficiency virus-infected children. The ACTG 254 Team. | 1999 | Antimicrob. Agents Chemother. | pmid:10348786 |
| Wierzbowski AK et al. | Expression of the mef(E) gene encoding the macrolide efflux pump protein increases in Streptococcus pneumoniae with increasing resistance to macrolides. | 2005 | Antimicrob. Agents Chemother. | pmid:16251306 |
| Jesus FP et al. | In vitro synergism observed with azithromycin, clarithromycin, minocycline, or tigecycline in association with antifungal agents against Pythium insidiosum. | 2014 | Antimicrob. Agents Chemother. | pmid:25001300 |
| Miura Y et al. | Maternal intravenous treatment with either azithromycin or solithromycin clears Ureaplasma parvum from the amniotic fluid in an ovine model of intrauterine infection. | 2014 | Antimicrob. Agents Chemother. | pmid:24982089 |
| Waites KB et al. | In Vitro Activities of Omadacycline (PTK 0796) and Other Antimicrobial Agents against Human Mycoplasmas and Ureaplasmas. | 2016 | Antimicrob. Agents Chemother. | pmid:27671057 |
| Gillis RJ et al. | Molecular basis of azithromycin-resistant Pseudomonas aeruginosa biofilms. | 2005 | Antimicrob. Agents Chemother. | pmid:16127063 |
| RÃos AM et al. | Microbiologic and immunologic evaluation of a single high dose of azithromycin for treatment of experimental Mycoplasma pneumoniae pneumonia. | 2005 | Antimicrob. Agents Chemother. | pmid:16127085 |
| Berry V et al. | Comparative bacteriological efficacy of pharmacokinetically enhanced amoxicillin-clavulanate against Streptococcus pneumoniae with elevated amoxicillin MICs and Haemophilus influenzae. | 2005 | Antimicrob. Agents Chemother. | pmid:15728883 |
| GarcÃa-Quintanilla M et al. | Inhibition of LpxC Increases Antibiotic Susceptibility in Acinetobacter baumannii. | 2016 | Antimicrob. Agents Chemother. | pmid:27270288 |
| Clark CL et al. | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. | 2007 | Antimicrob. Agents Chemother. | pmid:17876003 |
| Köhler T et al. | Ribosome protection prevents azithromycin-mediated quorum-sensing modulation and stationary-phase killing of Pseudomonas aeruginosa. | 2007 | Antimicrob. Agents Chemother. | pmid:17876004 |
| Yeruva L et al. | Differential susceptibilities to azithromycin treatment of chlamydial infection in the gastrointestinal tract and cervix. | 2013 | Antimicrob. Agents Chemother. | pmid:24100498 |
| Spangler SK et al. | Effect of CO2 on susceptibilities of anaerobes to erythromycin, azithromycin, clarithromycin, and roxithromycin. | 1994 | Antimicrob. Agents Chemother. | pmid:8192445 |
| Stamler DA et al. | Azithromycin pharmacokinetics and intracellular concentrations in Legionella pneumophila-infected and uninfected guinea pigs and their alveolar macrophages. | 1994 | Antimicrob. Agents Chemother. | pmid:8192446 |
| Reveneau N et al. | Bactericidal activity of first-choice antibiotics against gamma interferon-induced persistent infection of human epithelial cells by Chlamydia trachomatis. | 2005 | Antimicrob. Agents Chemother. | pmid:15855497 |
| Mizukane R et al. | Comparative in vitro exoenzyme-suppressing activities of azithromycin and other macrolide antibiotics against Pseudomonas aeruginosa. | 1994 | Antimicrob. Agents Chemother. | pmid:8203850 |
| Perronne C et al. | Activities of sparfloxacin, azithromycin, temafloxacin, and rifapentine compared with that of clarithromycin against multiplication of Mycobacterium avium complex within human macrophages. | 1991 | Antimicrob. Agents Chemother. | pmid:1656860 |
| Araujo FG and Remington JS | Synergistic activity of azithromycin and gamma interferon in murine toxoplasmosis. | 1991 | Antimicrob. Agents Chemother. | pmid:1656872 |
| Fass RJ | Erythromycin, clarithromycin, and azithromycin: use of frequency distribution curves, scattergrams, and regression analyses to compare in vitro activities and describe cross-resistance. | 1993 | Antimicrob. Agents Chemother. | pmid:8257127 |
| Taylor DE and Chang N | In vitro susceptibilities of Campylobacter jejuni and Campylobacter coli to azithromycin and erythromycin. | 1991 | Antimicrob. Agents Chemother. | pmid:1659309 |
| Wingard JB et al. | A novel cell-associated protection assay demonstrates the ability of certain antibiotics to protect ocular surface cell lines from subsequent clinical Staphylococcus aureus challenge. | 2011 | Antimicrob. Agents Chemother. | pmid:21628536 |
| Plouffe J et al. | Clinical efficacy of intravenous followed by oral azithromycin monotherapy in hospitalized patients with community-acquired pneumonia. The Azithromycin Intravenous Clinical Trials Group. | 2000 | Antimicrob. Agents Chemother. | pmid:10858333 |
| Skindersoe ME et al. | Effects of antibiotics on quorum sensing in Pseudomonas aeruginosa. | 2008 | Antimicrob. Agents Chemother. | pmid:18644954 |
| Jesus FP et al. | In Vitro and In Vivo Antimicrobial Activities of Minocycline in Combination with Azithromycin, Clarithromycin, or Tigecycline against Pythium insidiosum. | 2015 | Antimicrob. Agents Chemother. | pmid:26459895 |
| Critchley IA et al. | National and regional assessment of antimicrobial resistance among community-acquired respiratory tract pathogens identified in a 2005-2006 U.S. Faropenem surveillance study. | 2007 | Antimicrob. Agents Chemother. | pmid:17908940 |
| Salman S et al. | Optimal Antimalarial Dose Regimens for Sulfadoxine-Pyrimethamine with or without Azithromycin in Pregnancy Based on Population Pharmacokinetic Modeling. | 2017 | Antimicrob. Agents Chemother. | pmid:28242669 |
| Unemo M et al. | High in vitro susceptibility to the novel spiropyrimidinetrione ETX0914 (AZD0914) among 873 contemporary clinical Neisseria gonorrhoeae isolates from 21 European countries from 2012 to 2014. | 2015 | Antimicrob. Agents Chemother. | pmid:26077246 |
| Bogdanovich T et al. | Effect of efflux on telithromycin and macrolide susceptibility in Haemophilus influenzae. | 2006 | Antimicrob. Agents Chemother. | pmid:16495248 |
| Lai PC and Walters JD | Azithromycin kills invasive Aggregatibacter actinomycetemcomitans in gingival epithelial cells. | 2013 | Antimicrob. Agents Chemother. | pmid:23274657 |
| Soares GM et al. | Effects of azithromycin, metronidazole, amoxicillin, and metronidazole plus amoxicillin on an in vitro polymicrobial subgingival biofilm model. | 2015 | Antimicrob. Agents Chemother. | pmid:25733510 |
| Parry CM et al. | Clinically and microbiologically derived azithromycin susceptibility breakpoints for Salmonella enterica serovars Typhi and Paratyphi A. | 2015 | Antimicrob. Agents Chemother. | pmid:25733500 |