| MeSH term | MeSH ID | Detail |
|---|---|---|
| Escherichia coli Infections | D004927 | 17 associated lipids |
| Exanthema | D005076 | 11 associated lipids |
| Eye Diseases | D005128 | 12 associated lipids |
| Eyelid Diseases | D005141 | 4 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Fetal Membranes, Premature Rupture | D005322 | 4 associated lipids |
| Fever | D005334 | 35 associated lipids |
| Fever of Unknown Origin | D005335 | 3 associated lipids |
| Food Hypersensitivity | D005512 | 7 associated lipids |
| Furunculosis | D005667 | 2 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Misra R and Prasad KN | Antimicrobial susceptibility to azithromycin among Salmonella enterica Typhi and Paratyphi A isolates from India. | 2016 | J. Med. Microbiol. | pmid:27902389 |
| Hanssens L et al. | The clinical benefits of long-term supplementation with omega-3 fatty acids in cystic fibrosis patients - A pilot study. | 2016 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:27154364 |
| Wang A et al. | Effects of Fluoroquinolones and Azithromycin on Biofilm Formation of Stenotrophomonas maltophilia. | 2016 | Sci Rep | pmid:27405358 |
| Menzel M et al. | Azithromycin induces anti-viral effects in cultured bronchial epithelial cells from COPD patients. | 2016 | Sci Rep | pmid:27350308 |
| O'Beirne SL et al. | Trust Your Instincts. Surgical Lung Biopsy with Normal Chest Imaging in a 49-Year-Old Man with Progressive Dyspnea. | 2016 | Ann Am Thorac Soc | pmid:27144798 |
| Sadatsafavi M et al. | The Association Between Rate and Severity of Exacerbations in Chronic Obstructive Pulmonary Disease: An Application of a Joint Frailty-Logistic Model. | 2016 | Am. J. Epidemiol. | pmid:27737842 |
| Nair S et al. | WGS for surveillance of antimicrobial resistance: a pilot study to detect the prevalence and mechanism of resistance to azithromycin in a UK population of non-typhoidal Salmonella. | 2016 | J. Antimicrob. Chemother. | pmid:27585964 |
| Mwingira UJ et al. | Progress of Trachoma Mapping in Mainland Tanzania: Results of Baseline Surveys from 2012 to 2014. | 2016 | Ophthalmic Epidemiol | pmid:27775455 |
| Wind CM et al. | Time to clearance of Chlamydia trachomatis RNA and DNA after treatment in patients coinfected with Neisseria gonorrhoeae - a prospective cohort study. | 2016 | BMC Infect. Dis. | pmid:27724878 |
| Yasuda M et al. | Remarkable increase of Neisseria gonorrhoeae with decreased susceptibility of azithromycin and increase in the failure of azithromycin therapy in male gonococcal urethritis in Sendai in 2015. | 2016 | J. Infect. Chemother. | pmid:27578029 |
| Tita AT et al. | Adjunctive Azithromycin Prophylaxis for Cesarean Delivery. | 2016 | N. Engl. J. Med. | pmid:27682034 |
| Committee Opinion No. 645: Dual Therapy for Gonococcal Infections. | 2016 | Obstet Gynecol | pmid:27548425 | |
| Waites KB et al. | In Vitro Activities of Omadacycline (PTK 0796) and Other Antimicrobial Agents against Human Mycoplasmas and Ureaplasmas. | 2016 | Antimicrob. Agents Chemother. | pmid:27671057 |
| Committee Opinion No. 645 Summary: Dual Therapy for Gonococcal Infections. | 2016 | Obstet Gynecol | pmid:27548417 | |
| Li S et al. | Two case reports: Whole genome sequencing of two clinical macrolide-resistant Mycoplasma pneumoniae isolates with different responses to azithromycin. | 2016 | Medicine (Baltimore) | pmid:27661056 |
| Mustapha NA et al. | Impact of different antibiotics on methane production using waste-activated sludge: mechanisms and microbial community dynamics. | 2016 | Appl. Microbiol. Biotechnol. | pmid:27531514 |
| Brunner A et al. | Emerging azithromycin-resistance among the Neisseria gonorrhoeae strains isolated in Hungary. | 2016 | Ann. Clin. Microbiol. Antimicrob. | pmid:27646968 |
| Molini BJ et al. | Macrolide Resistance in Treponema pallidum Correlates With 23S rDNA Mutations in Recently Isolated Clinical Strains. | 2016 | Sex Transm Dis | pmid:27513385 |
| Regnath T et al. | Antimicrobial resistance of Neisseria gonorrhoeae isolates in south-west Germany, 2004 to 2015: increasing minimal inhibitory concentrations of tetracycline but no resistance to third-generation cephalosporins. | 2016 | Euro Surveill. | pmid:27632642 |
| Falay D et al. | Microbiological, clinical and molecular findings of non-typhoidal Salmonella bloodstream infections associated with malaria, Oriental Province, Democratic Republic of the Congo. | 2016 | BMC Infect. Dis. | pmid:27286886 |
| Horner PJ et al. | 2016 European guideline on the management of non-gonococcal urethritis. | 2016 | Int J STD AIDS | pmid:27147267 |
| El-Shitany NA and El-Desoky K | Protective Effects of Carvedilol and Vitamin C against Azithromycin-Induced Cardiotoxicity in Rats via Decreasing ROS, IL1-β, and TNF-α Production and Inhibiting NF-κB and Caspase-3 Expression. | 2016 | Oxid Med Cell Longev | pmid:27274777 |
| Kreuter A and Wieland U | Azithromycin versus Doxycycline for Chlamydia. | 2016 | N. Engl. J. Med. | pmid:27144858 |
| GarcÃa-Quintanilla M et al. | Inhibition of LpxC Increases Antibiotic Susceptibility in Acinetobacter baumannii. | 2016 | Antimicrob. Agents Chemother. | pmid:27270288 |
| Schachter J | Azithromycin versus Doxycycline for Chlamydia. | 2016 | N. Engl. J. Med. | pmid:27144857 |
| Zhou QT et al. | How Much Surface Coating of Hydrophobic Azithromycin Is Sufficient to Prevent Moisture-Induced Decrease in Aerosolisation of Hygroscopic Amorphous Colistin Powder? | 2016 | AAPS J | pmid:27255350 |
| MUW researcher of the month Franz Ratzinger. | 2016 | Wien. Klin. Wochenschr. | pmid:27113348 | |
| Yuan ZF et al. | Clinically mild encephalitis/encephalopathy with a reversible splenial lesion associated with Mycoplasma pneumoniae infection. | 2016 | BMC Infect. Dis. | pmid:27230114 |
| Kloepfer KM | Azithromycin may prevent severe respiratory-infection-induced wheezing. | 2016 | J. Pediatr. | pmid:27112084 |
| Demczuk W et al. | Genomic Epidemiology and Molecular Resistance Mechanisms of Azithromycin-Resistant Neisseria gonorrhoeae in Canada from 1997 to 2014. | 2016 | J. Clin. Microbiol. | pmid:26935729 |
| Trac MH et al. | Macrolide antibiotics and the risk of ventricular arrhythmia in older adults. | 2016 | CMAJ | pmid:26903359 |
| Marks M et al. | Mass drug administration of azithromycin for trachoma reduces the prevalence of genital Chlamydia trachomatis infection in the Solomon Islands. | 2016 | Sex Transm Infect | pmid:26888658 |
| Economopoulos KP et al. | Prevention of antibiotic-associated metabolic syndrome in mice by intestinal alkaline phosphatase. | 2016 | Diabetes Obes Metab | pmid:26876427 |
| Kang JY et al. | Long-term azithromycin ameliorates not only airway inflammation but also remodeling in a murine model of chronic asthma. | 2016 | Pulm Pharmacol Ther | pmid:26778828 |
| Sridhar S et al. | High recurrence rate supports need for secondary prophylaxis in non-HIV patients with disseminated mycobacterium avium complex infection: a multi-center observational study. | 2016 | BMC Infect. Dis. | pmid:26861696 |
| Peters RP et al. | Gonococcal Conjunctivitis Despite Successful Treatment of Male Urethritis Syndrome. | 2016 | Sex Transm Dis | pmid:26760182 |
| Hodgson D et al. | The Effects of Azithromycin in Treatment-Resistant Cough: A Randomized, Double-Blind, Placebo-Controlled Trial. | 2016 | Chest | pmid:26836927 |
| Zheng Z et al. | Synthesis and antibacterial activity of novel 11-[3-[(arylcarbamoyl)oxy]propylamino]-11-deoxy-6-O-methyl-3-oxoerythromycin A 11-N,12-O-cyclic carbamate derivatives. | 2016 | J. Antibiot. | pmid:27118243 |
| Gratrix J et al. | A Retrospective Review of Treatment Failures Using Azithromycin and Doxycycline in the Treatment of Rectal Chlamydia Infections in Women and Men Who Have Sex With Men. | 2016 | Sex Transm Dis | pmid:26760180 |
| Kumaraswamy M et al. | Standard susceptibility testing overlooks potent azithromycin activity and cationic peptide synergy against MDR Stenotrophomonas maltophilia. | 2016 | J. Antimicrob. Chemother. | pmid:26832758 |
| Arikan S et al. | Effect of Topically Applied Azithromycin on Corneal Epithelial and Endothelial Apoptosis in a Rat Model of Corneal Alkali Burn. | 2016 | Cornea | pmid:26751994 |
| Zhou T et al. | Fabrication of a Selective and Sensitive Sensor Based on Molecularly Imprinted Polymer/Acetylene Black for the Determination of Azithromycin in Pharmaceuticals and Biological Samples. | 2016 | PLoS ONE | pmid:26820753 |
| Russell DW et al. | Disease phenotyping in chronic obstructive pulmonary disease: the neutrophilic endotype. | 2016 | Curr Opin Pulm Med | pmid:26717512 |
| Manavi K et al. | Comparison of doxycycline with azithromycin in treatment of pharyngeal chlamydia infection. | 2016 | Int J STD AIDS | pmid:26511655 |
| Nicholson TT et al. | Assessing potential risks of treatment with long-term azithromycin in COPD patients: long-term oxygen users beware? | 2016 | Ir J Med Sci | pmid:26502012 |
| Deguchi T et al. | Multidrug-Resistant Mycoplasma genitalium Is Increasing. | 2016 | Clin. Infect. Dis. | pmid:26494825 |
| Kong FY et al. | Reply to Deguchi et al. | 2016 | Clin. Infect. Dis. | pmid:26494824 |
| Osborne LG et al. | Enteric fever in a British soldier from Sierra Leone. | 2016 | J R Army Med Corps | pmid:26243802 |
| Wright H et al. | Evaluating Guideline-Recommended Antibiotic Practices for Childhood Respiratory Infections: Is It Time to Consider Case-Based Formats? | 2016 | Clin Pediatr (Phila) | pmid:25986442 |
| Chang CC et al. | Disseminated cat-scratch disease: case report and review of the literature. | 2016 | Paediatr Int Child Health | pmid:25940800 |