Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Paratyphoid Fever D010284 1 associated lipids
Pemphigus D010392 3 associated lipids
Penile Diseases D010409 2 associated lipids
Peptic Ulcer D010437 19 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Pericoronitis D010497 2 associated lipids
Periodontitis D010518 22 associated lipids
Pharyngeal Diseases D010608 4 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
Pneumonia, Pneumococcal D011018 3 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Pregnancy Complications, Infectious D011251 11 associated lipids
Prostatitis D011472 5 associated lipids
Protozoan Infections D011528 6 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Psoriasis D011565 47 associated lipids
Psychomotor Agitation D011595 3 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Respiratory Tract Infections D012141 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Benn K et al. Bradycardia and Hypothermia Complicating Azithromycin Treatment. 2017 Am J Case Rep pmid:28798290
Mei J et al. Implications of intrapartum azithromycin on neonatal microbiota. 2017 Lancet Infect Dis pmid:28244378
Bergeron A et al. Effect of Azithromycin on Airflow Decline-Free Survival After Allogeneic Hematopoietic Stem Cell Transplant: The ALLOZITHRO Randomized Clinical Trial. 2017 JAMA pmid:28787506
Zhang M et al. Electrophysiologic Studies on the Risks and Potential Mechanism Underlying the Proarrhythmic Nature of Azithromycin. 2017 Cardiovasc. Toxicol. pmid:28213753
Hoogewoud F et al. Prognostic Factors in Syphilitic Uveitis. 2017 Ophthalmology pmid:28779905
Lahra MM et al. Treatment guidelines after an outbreak of azithromycin-resistant Neisseria gonorrhoeae in South Australia. 2017 Lancet Infect Dis pmid:28134103
Bloch EM et al. Antibiotic Resistance in Young Children in Kilosa District, Tanzania 4 Years after Mass Distribution of Azithromycin for Trachoma Control. 2017 Am. J. Trop. Med. Hyg. pmid:28722638
Feng X and Liu J A combination of irsogladine maleate and azithromycin exhibits addictive protective effects in LPS-induced human gingival epithelial cells. 2017 Pharmazie pmid:29441859
González-Beiras C et al. Yaws Osteoperiostitis Treated with Single-Dose Azithromycin. 2017 Am. J. Trop. Med. Hyg. pmid:28193743
Ivanová L et al. Estimation of amount of selected pharmaceuticals sorbed onto digested sludge from wastewater treatment plant Bratislava-Petržalka. 2017 Environ. Res. pmid:28183039
Thakur SD et al. Resistance to Ceftriaxone and Azithromycin in Neisseria gonorrhoeae Isolates From 7 Countries of South America and the Caribbean: 2010-2011. 2017 Sex Transm Dis pmid:28178114
Boggess KA et al. Risk Factors for Postcesarean Maternal Infection in a Trial of Extended-Spectrum Antibiotic Prophylaxis. 2017 Obstet Gynecol pmid:28178058
Hallström H et al. Open flap debridement of peri-implantitis with or without adjunctive systemic antibiotics: A randomized clinical trial. 2017 J. Clin. Periodontol. pmid:28836279
Subedi Y Around Manaslu Ultramarathon: Diarrhea Is Still the King. 2017 Wilderness Environ Med pmid:28735656
McConnell K and Shields M Azithromycin for episodes with asthma-like symptoms in young children aged 1-3 years. 2017 Arch Dis Child Educ Pract Ed pmid:28735295
Kong FY et al. Pharmacokinetics of a single 1g dose of azithromycin in rectal tissue in men. 2017 PLoS ONE pmid:28350806
Bornstein M et al. Factors Associated With Primary Care Physician Knowledge of the Recommended Regimen for Treating Gonorrhea. 2017 Sex Transm Dis pmid:27898574
Checa R et al. Efficacy, safety and tolerance of imidocarb dipropionate versus atovaquone or buparvaquone plus azithromycin used to treat sick dogs naturally infected with the Babesia microti-like piroplasm. 2017 Parasit Vectors pmid:28292316
Ishiguro N et al. Therapeutic efficacy of azithromycin, clarithromycin, minocycline and tosufloxacin against macrolide-resistant and macrolide-sensitive Mycoplasma pneumoniae pneumonia in pediatric patients. 2017 PLoS ONE pmid:28288170
Babić I et al. Therapeutic efficacy of azithromycin and acetylcysteine in chronic otitis media with effusion. 2017 Eur Arch Otorhinolaryngol pmid:27873023
Demczuk W et al. Neisseria gonorrhoeae Sequence Typing for Antimicrobial Resistance, a Novel Antimicrobial Resistance Multilocus Typing Scheme for Tracking Global Dissemination of N. gonorrhoeae Strains. 2017 J. Clin. Microbiol. pmid:28228492
Yan M et al. Synthesis and antibacterial activity of novel 3-O-descladinosylazithromycin derivatives. 2017 Eur J Med Chem pmid:27836198
Ginouvès M et al. In Vitro Sensitivity of Cutaneous Leishmania Promastigote Isolates Circulating in French Guiana to a Set of Drugs. 2017 Am. J. Trop. Med. Hyg. pmid:28167598
Giguère S Treatment of Infections Caused by Rhodococcus equi. 2017 Vet. Clin. North Am. Equine Pract. pmid:28161038
Daimee UA et al. A 77-year-old man with fever and night sweats. 2017 Eur. J. Intern. Med. pmid:27765389
Illia R et al. Role of cervical cerclage and prolonged antibiotic therapy with azithromycin in patients with previous perinatal loss amnionitis. 2017 J. Matern. Fetal. Neonatal. Med. pmid:27094535
Massip C et al. Macrolide resistance in Legionella pneumophila: the role of LpeAB efflux pump. 2017 J. Antimicrob. Chemother. pmid:28137939
Jover-García J et al. [In-vitro activity of azithromycin in faecal isolates of Aeromonas hydrophila]. 2017 An Pediatr (Barc) pmid:27686393
Srivastava S et al. A 'shock and awe' thioridazine and moxifloxacin combination-based regimen for pulmonary Mycobacterium avium-intracellulare complex disease. 2017 J. Antimicrob. Chemother. pmid:28922810
Srivastava S et al. Failure of the azithromycin and ethambutol combination regimen in the hollow-fibre system model of pulmonary Mycobacterium avium infection is due to acquired resistance. 2017 J. Antimicrob. Chemother. pmid:28922805
Cole MJ et al. Overall Low Extended-Spectrum Cephalosporin Resistance but high Azithromycin Resistance in Neisseria gonorrhoeae in 24 European Countries, 2015. 2017 BMC Infect. Dis. pmid:28893203
Salman S et al. Optimal Antimalarial Dose Regimens for Sulfadoxine-Pyrimethamine with or without Azithromycin in Pregnancy Based on Population Pharmacokinetic Modeling. 2017 Antimicrob. Agents Chemother. pmid:28242669
Mathew A et al. Antimicrobial and Immunomodulatory Surface-Functionalized Electrospun Membranes for Bone Regeneration. 2017 Adv Healthc Mater pmid:28240815
Teng F et al. In vitro characterization of pH-sensitive azithromycin-loaded methoxy poly (ethylene glycol)-block-poly (aspartic acid-graft-imidazole) micelles. 2017 J Colloid Interface Sci pmid:28209540
Koop AH et al. 56-Year-Old Woman With Cough and Fatigue for 1 Week. 2017 Mayo Clin. Proc. pmid:28110893
Quinn KL et al. Macrolides, Digoxin Toxicity and the Risk of Sudden Death: A Population-Based Study. 2017 Drug Saf pmid:28421551
Diniz LM et al. Bacillary angiomatosis with bone invasion. 2016 Nov-Dec An Bras Dermatol pmid:28099606
Akoglu G et al. Erlotinib-induced purpuric papulopustular eruption treated with pulsed azithromycin. 2016 May-Jun Indian J Pharmacol pmid:27298507
Latif SA et al. Azithromycin buccal patch in treatment of chronic periodontitis. 2016 Mar-Apr Indian J Pharmacol pmid:27127325
Oliveira IS et al. Evaluation of the improvement of quality of life with Azithromycin in the treatment of eosinophilic nasal polyposis. 2016 Mar-Apr Braz J Otorhinolaryngol pmid:26601998
Chatterjee S et al. Azithromycin susceptibility among clinical isolates of Salmonella: Interfacing guidelines with routine practices. 2016 Jul-Sep Indian J Med Microbiol pmid:27514976
Hazra A Author Reply. 2016 Jan-Feb Indian J Pharmacol pmid:26997735
Das S and Mohanty M Comparative evaluation of 2 g single dose versus conventional dose azithromycin in uncomplicated skin and skin structure infections. 2016 Jan-Feb Indian J Pharmacol pmid:26997734
Das A et al. Azithromycin induced bullous fixed drug eruption. 2016 Jan-Feb Indian J Pharmacol pmid:26997729
Cheng GS et al. Lung Function Trajectory in Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Cell Transplant. 2016 Ann Am Thorac Soc pmid:27513368
Kobuchi S et al. Transport of Azithromycin into Extravascular Space in Rats. 2016 Antimicrob. Agents Chemother. pmid:27600045
Wang Z and Meenach SA Synthesis and Characterization of Nanocomposite Microparticles (nCmP) for the Treatment of Cystic Fibrosis-Related Infections. 2016 Pharm. Res. pmid:27091030
Swatton JE et al. Impact of Azithromycin on the Quorum Sensing-Controlled Proteome of Pseudomonas aeruginosa. 2016 PLoS ONE pmid:26808156
Al-Hity A and Lockington D Oral azithromycin as the systemic treatment of choice in the treatment of meibomian gland disease. 2016 Clin. Experiment. Ophthalmol. pmid:26441357
Wu TS et al. Postcesarean section wound infection caused by Mycobacterium massiliense. 2016 J Microbiol Immunol Infect pmid:26350122