| MeSH term | MeSH ID | Detail |
|---|---|---|
| Periodontitis | D010518 | 22 associated lipids |
| Gastrointestinal Diseases | D005767 | 20 associated lipids |
| Vomiting | D014839 | 21 associated lipids |
| Fever | D005334 | 35 associated lipids |
| Anaphylaxis | D000707 | 35 associated lipids |
| Pregnancy Complications, Infectious | D011251 | 11 associated lipids |
| Toxoplasmosis | D014123 | 9 associated lipids |
| Toxoplasmosis, Congenital | D014125 | 2 associated lipids |
| Otitis Media with Effusion | D010034 | 9 associated lipids |
| Shock, Septic | D012772 | 11 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gupta A and Khanna S | Repeat Clostridium difficile Testing. | 2016 | JAMA | pmid:27959982 |
| Espadas D et al. | Lack of effect of azithromycin on QT interval in children: a cohort study. | 2016 | Arch. Dis. Child. | pmid:27515186 |
| Hanssens L et al. | The clinical benefits of long-term supplementation with omega-3 fatty acids in cystic fibrosis patients - A pilot study. | 2016 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:27154364 |
| Zhou Y et al. | Azithromycin therapy during respiratory syncytial virus bronchiolitis: Upper airway microbiome alterations and subsequent recurrent wheeze. | 2016 | J. Allergy Clin. Immunol. | pmid:27339392 |
| Rosenthal PJ | Azithromycin for Malaria? | 2016 | Am. J. Trop. Med. Hyg. | pmid:27215296 |
| Elshafie BE et al. | The Epidemiology of Trachoma in Darfur States and Khartoum State, Sudan: Results of 32 Population-Based Prevalence Surveys. | 2016 | Ophthalmic Epidemiol | pmid:27841721 |
| Sadatsafavi M et al. | The Association Between Rate and Severity of Exacerbations in Chronic Obstructive Pulmonary Disease: An Application of a Joint Frailty-Logistic Model. | 2016 | Am. J. Epidemiol. | pmid:27737842 |
| Nair S et al. | WGS for surveillance of antimicrobial resistance: a pilot study to detect the prevalence and mechanism of resistance to azithromycin in a UK population of non-typhoidal Salmonella. | 2016 | J. Antimicrob. Chemother. | pmid:27585964 |
| Mwingira UJ et al. | Progress of Trachoma Mapping in Mainland Tanzania: Results of Baseline Surveys from 2012 to 2014. | 2016 | Ophthalmic Epidemiol | pmid:27775455 |
| Wind CM et al. | Time to clearance of Chlamydia trachomatis RNA and DNA after treatment in patients coinfected with Neisseria gonorrhoeae - a prospective cohort study. | 2016 | BMC Infect. Dis. | pmid:27724878 |
| Weckmann M et al. | Treatment with rhDNase in patients with cystic fibrosis alters in-vitro CHIT-1 activity of isolated leucocytes. | 2016 | Clin. Exp. Immunol. | pmid:27324468 |
| Oliveira GN et al. | Congenital dacryocystocoele with prenatal diagnosis. | 2016 | BMJ Case Rep | pmid:27166005 |
| Falay D et al. | Microbiological, clinical and molecular findings of non-typhoidal Salmonella bloodstream infections associated with malaria, Oriental Province, Democratic Republic of the Congo. | 2016 | BMC Infect. Dis. | pmid:27286886 |
| Horner PJ et al. | 2016 European guideline on the management of non-gonococcal urethritis. | 2016 | Int J STD AIDS | pmid:27147267 |
| El-Shitany NA and El-Desoky K | Protective Effects of Carvedilol and Vitamin C against Azithromycin-Induced Cardiotoxicity in Rats via Decreasing ROS, IL1-β, and TNF-α Production and Inhibiting NF-κB and Caspase-3 Expression. | 2016 | Oxid Med Cell Longev | pmid:27274777 |
| Kreuter A and Wieland U | Azithromycin versus Doxycycline for Chlamydia. | 2016 | N. Engl. J. Med. | pmid:27144858 |
| GarcÃa-Quintanilla M et al. | Inhibition of LpxC Increases Antibiotic Susceptibility in Acinetobacter baumannii. | 2016 | Antimicrob. Agents Chemother. | pmid:27270288 |
| Demczuk W et al. | Genomic Epidemiology and Molecular Resistance Mechanisms of Azithromycin-Resistant Neisseria gonorrhoeae in Canada from 1997 to 2014. | 2016 | J. Clin. Microbiol. | pmid:26935729 |
| Mohotti JE et al. | A case of bilateral endogenous bacterial endophthalmitis from Streptococcus pneumoniae bacteraemia. | 2016 | Med. J. Aust. | pmid:26821111 |
| Trac MH et al. | Macrolide antibiotics and the risk of ventricular arrhythmia in older adults. | 2016 | CMAJ | pmid:26903359 |
| Marks M et al. | Mass drug administration of azithromycin for trachoma reduces the prevalence of genital Chlamydia trachomatis infection in the Solomon Islands. | 2016 | Sex Transm Infect | pmid:26888658 |
| Economopoulos KP et al. | Prevention of antibiotic-associated metabolic syndrome in mice by intestinal alkaline phosphatase. | 2016 | Diabetes Obes Metab | pmid:26876427 |
| Kang JY et al. | Long-term azithromycin ameliorates not only airway inflammation but also remodeling in a murine model of chronic asthma. | 2016 | Pulm Pharmacol Ther | pmid:26778828 |
| Manavi K et al. | Comparison of doxycycline with azithromycin in treatment of pharyngeal chlamydia infection. | 2016 | Int J STD AIDS | pmid:26511655 |
| Williams KM et al. | Fluticasone, Azithromycin, and Montelukast Treatment for New-Onset Bronchiolitis Obliterans Syndrome after Hematopoietic Cell Transplantation. | 2016 | Biol. Blood Marrow Transplant. | pmid:26475726 |
| Nicholson TT et al. | Assessing potential risks of treatment with long-term azithromycin in COPD patients: long-term oxygen users beware? | 2016 | Ir J Med Sci | pmid:26502012 |
| Deguchi T et al. | Multidrug-Resistant Mycoplasma genitalium Is Increasing. | 2016 | Clin. Infect. Dis. | pmid:26494825 |
| Kasten G et al. | Development of low density azithromycin-loaded polycaprolactone microparticles for pulmonary delivery. | 2016 | Drug Dev Ind Pharm | pmid:26266961 |
| Osborne LG et al. | Enteric fever in a British soldier from Sierra Leone. | 2016 | J R Army Med Corps | pmid:26243802 |
| Wright H et al. | Evaluating Guideline-Recommended Antibiotic Practices for Childhood Respiratory Infections: Is It Time to Consider Case-Based Formats? | 2016 | Clin Pediatr (Phila) | pmid:25986442 |
| Dey SK et al. | Comparative evaluation of 2 g single dose versus conventional dose azithromycin in uncomplicated skin and skin structure infections. | 2015 Jul-Aug | Indian J Pharmacol | pmid:26288467 |
| Ercan E et al. | Effects of azithromycin versus metronidazole-amoxicillin combination as an adjunct to nonsurgical periodontal therapy of generalized aggressive periodontitis. | 2015 Jul-Aug | Niger J Clin Pract | pmid:25966723 |
| Walicka-Serzysko K and Sands D | The clinical presentations of pulmonary aspergillosis in children with cystic fibrosis - preliminary report. | 2015 Jan-Mar | Dev Period Med | pmid:26003072 |
| Pandhi D et al. | Author's Response--The efficacy of azithromycin in pityriasis rosea: a randomized, double-blind, placebo-controlled trial. | 2015 Jan-Feb | Indian J Dermatol Venereol Leprol | pmid:25566901 |
| Drago F et al. | The efficacy of macrolides and acyclovir in pityriasis rosea. | 2015 Jan-Feb | Indian J Dermatol Venereol Leprol | pmid:25566900 |
| Kong FY et al. | The efficacy of azithromycin and doxycycline for the treatment of rectal chlamydia infection: a systematic review and meta-analysis. | 2015 | J. Antimicrob. Chemother. | pmid:25637520 |
| Saini H et al. | Azithromycin and ciprofloxacin: a possible synergistic combination against Pseudomonas aeruginosa biofilm-associated urinary tract infections. | 2015 | Int. J. Antimicrob. Agents | pmid:25604277 |
| Kadova Z et al. | IL-1 receptor blockade alleviates endotoxin-mediated impairment of renal drug excretory functions in rats. | 2015 | Am. J. Physiol. Renal Physiol. | pmid:25503728 |
| Keenan JD et al. | Evidence for clonal expansion after antibiotic selection pressure: pneumococcal multilocus sequence types before and after mass azithromycin treatments. | 2015 | J. Infect. Dis. | pmid:25293366 |
| ACOG Committee Opinion No. 645: Dual Therapy for Gonococcal Infections. | 2015 | Obstet Gynecol | pmid:26488526 | |
| Shibahara D et al. | Falciparum Malaria Incidentally Pretreated with Azithromycin. | 2015 | Intern. Med. | pmid:26424314 |
| Wei HX et al. | A Systematic Review and Meta-Analysis of the Efficacy of Anti-Toxoplasma gondii Medicines in Humans. | 2015 | PLoS ONE | pmid:26394212 |
| Zhanel GG et al. | Clinical cure rates in subjects treated with azithromycin for community-acquired respiratory tract infections caused by azithromycin-susceptible or azithromycin-resistant Streptococcus pneumoniae: analysis of Phase 3 clinical trial data-authors' response. | 2015 | J. Antimicrob. Chemother. | pmid:26242414 |
| Horner PJ | Editorial Commentary: Mycoplasma genitalium and Declining Treatment Efficacy of Azithromycin 1 g: What Can We Do? | 2015 | Clin. Infect. Dis. | pmid:26240204 |
| Unemo M et al. | High in vitro susceptibility to the novel spiropyrimidinetrione ETX0914 (AZD0914) among 873 contemporary clinical Neisseria gonorrhoeae isolates from 21 European countries from 2012 to 2014. | 2015 | Antimicrob. Agents Chemother. | pmid:26077246 |
| Cowling CS et al. | National trachoma surveillance annual report, 2012. | 2015 | Commun Dis Intell Q Rep | pmid:26063088 |
| Lahra MM | Australian Gonococcal Surveillance Programme annual report, 2013. | 2015 | Commun Dis Intell Q Rep | pmid:26063087 |
| Baker KS et al. | Intercontinental dissemination of azithromycin-resistant shigellosis through sexual transmission: a cross-sectional study. | 2015 | Lancet Infect Dis | pmid:25936611 |
| Soares GM et al. | Effects of azithromycin, metronidazole, amoxicillin, and metronidazole plus amoxicillin on an in vitro polymicrobial subgingival biofilm model. | 2015 | Antimicrob. Agents Chemother. | pmid:25733510 |
| Parry CM et al. | Clinically and microbiologically derived azithromycin susceptibility breakpoints for Salmonella enterica serovars Typhi and Paratyphi A. | 2015 | Antimicrob. Agents Chemother. | pmid:25733500 |