| MeSH term | MeSH ID | Detail |
|---|---|---|
| Periodontitis | D010518 | 22 associated lipids |
| Gastrointestinal Diseases | D005767 | 20 associated lipids |
| Vomiting | D014839 | 21 associated lipids |
| Fever | D005334 | 35 associated lipids |
| Anaphylaxis | D000707 | 35 associated lipids |
| Pregnancy Complications, Infectious | D011251 | 11 associated lipids |
| Toxoplasmosis | D014123 | 9 associated lipids |
| Toxoplasmosis, Congenital | D014125 | 2 associated lipids |
| Otitis Media with Effusion | D010034 | 9 associated lipids |
| Shock, Septic | D012772 | 11 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gupta A and Khanna S | Repeat Clostridium difficile Testing. | 2016 | JAMA | pmid:27959982 |
| Martande SS et al. | Clinical and microbiological effects of systemic azithromycin in adjunct to nonsurgical periodontal therapy in treatment of Aggregatibacter actinomycetemcomitans associated periodontitis: a randomized placebo-controlled clinical trial. | 2016 | J Investig Clin Dent | pmid:25044531 |
| Hanssens L et al. | The clinical benefits of long-term supplementation with omega-3 fatty acids in cystic fibrosis patients - A pilot study. | 2016 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:27154364 |
| Mougari F et al. | Infections caused by Mycobacterium abscessus: epidemiology, diagnostic tools and treatment. | 2016 | Expert Rev Anti Infect Ther | pmid:27690688 |
| Johnston SL et al. | Azithromycin for Acute Exacerbations of Asthma : The AZALEA Randomized Clinical Trial. | 2016 | JAMA Intern Med | pmid:27653939 |
| Zhao X et al. | Sensitive and Simplified Detection of Antibiotic Influence on the Dynamic and Versatile Changes of Fecal Short-Chain Fatty Acids. | 2016 | PLoS ONE | pmid:27907030 |
| Mosquera RA et al. | Anti-inflammatory effect of prophylactic macrolides on children with chronic lung disease: a protocol for a double-blinded randomised controlled trial. | 2016 | BMJ Open | pmid:27638496 |
| Kissinger PJ et al. | Azithromycin Treatment Failure for Chlamydia trachomatis Among Heterosexual Men With Nongonococcal Urethritis. | 2016 | Sex Transm Dis | pmid:27631353 |
| Nielsen HL et al. | Azithromycin vs. Placebo for the Clinical Outcome in Campylobacter concisus Diarrhoea in Adults: A Randomized, Double-Blinded, Placebo-Controlled Clinical Trial. | 2016 | PLoS ONE | pmid:27893820 |
| Tepper M et al. | Mass Treatment with Single-Dose Azithromycin for Yaws. | 2016 | N. Engl. J. Med. | pmid:27626527 |
| Phiri K et al. | Parasitological Clearance Rates and Drug Concentrations of a Fixed Dose Combination of Azithromycin-Chloroquine in Asymptomatic Pregnant Women with Plasmodium Falciparum Parasitemia: An Open-Label, Non-Comparative Study in Sub-Saharan Africa. | 2016 | PLoS ONE | pmid:27861509 |
| Eckhoff G et al. | Mass Treatment with Single-Dose Azithromycin for Yaws. | 2016 | N. Engl. J. Med. | pmid:27626526 |
| Peart JM et al. | Sporotrichoid fluctuant nodules. | 2016 | Cutis | pmid:27622258 |
| Elshafie BE et al. | The Epidemiology of Trachoma in Darfur States and Khartoum State, Sudan: Results of 32 Population-Based Prevalence Surveys. | 2016 | Ophthalmic Epidemiol | pmid:27841721 |
| Sadatsafavi M et al. | The Association Between Rate and Severity of Exacerbations in Chronic Obstructive Pulmonary Disease: An Application of a Joint Frailty-Logistic Model. | 2016 | Am. J. Epidemiol. | pmid:27737842 |
| Katanami Y et al. | Six Cases of Paratyphoid Fever Due to Salmonella Paratyphi A in Travelers Returning from Myanmar Between July 2014 and August 2015. | 2016 | Am. J. Trop. Med. Hyg. | pmid:27352874 |
| Mertens TC et al. | Azithromycin differentially affects the IL-13-induced expression profile in human bronchial epithelial cells. | 2016 | Pulm Pharmacol Ther | pmid:27246785 |
| Wang X et al. | Increased therapeutic efficacy of combination of azithromycin and ceftazidime on Pseudomonas aeruginosa biofilm in an animal model of ureteral stent infection. | 2016 | BMC Microbiol. | pmid:27341798 |
| Das S et al. | Revisit of fluoroquinolone and azithromycin susceptibility breakpoints for Salmonella enterica serovar Typhi. | 2016 | J. Med. Microbiol. | pmid:27221661 |
| Fifer H et al. | Failure of Dual Antimicrobial Therapy in Treatment of Gonorrhea. | 2016 | N. Engl. J. Med. | pmid:27332921 |
| Bacharier LB et al. | Early Azithromycin Treatment to Prevent Severe Lower Respiratory Tract Illnesses in Children--Reply. | 2016 | JAMA | pmid:27187309 |
| Gesink D et al. | Mycoplasma genitalium in Toronto, Ont: Estimates of prevalence and macrolide resistance. | 2016 | Can Fam Physician | pmid:27331225 |
| Fleming-Dutra KE et al. | Early Azithromycin Treatment to Prevent Severe Lower Respiratory Tract Illnesses in Children. | 2016 | JAMA | pmid:27187308 |
| Kimani J et al. | Efficacy and Safety of Azithromycin-Chloroquine versus Sulfadoxine-Pyrimethamine for Intermittent Preventive Treatment of Plasmodium falciparum Malaria Infection in Pregnant Women in Africa: An Open-Label, Randomized Trial. | 2016 | PLoS ONE | pmid:27326859 |
| Morgan R et al. | Unusual cause of lymphangitis in a 2-year-old boy. | 2016 | BMJ Case Rep | pmid:27181743 |
| Weckmann M et al. | Treatment with rhDNase in patients with cystic fibrosis alters in-vitro CHIT-1 activity of isolated leucocytes. | 2016 | Clin. Exp. Immunol. | pmid:27324468 |
| Kong FY et al. | Higher organism load associated with failure of azithromycin to treat rectal chlamydia. | 2016 | Epidemiol. Infect. | pmid:27180823 |
| Oliveira GN et al. | Congenital dacryocystocoele with prenatal diagnosis. | 2016 | BMJ Case Rep | pmid:27166005 |
| Falay D et al. | Microbiological, clinical and molecular findings of non-typhoidal Salmonella bloodstream infections associated with malaria, Oriental Province, Democratic Republic of the Congo. | 2016 | BMC Infect. Dis. | pmid:27286886 |
| Mathew JL et al. | Oral Azithromycin for Acute Episodic Airway Symptoms in Young Children: Evidence-based Medicine Viewpoint. | 2016 | Indian Pediatr | pmid:27029689 |
| Roca A et al. | Oral azithromycin given during labour decreases bacterial carriage in the mothers and their offspring: a double-blind randomized trial. | 2016 | Clin. Microbiol. Infect. | pmid:27026482 |
| Oey M and Malhotra P | Azithromycin and ceftriaxone combination treatment for relapsed Salmonella Paratyphi A bacteraemia. | 2016 | J Travel Med | pmid:26858276 |
| DeCoster B et al. | Expedited Partner Therapy: Clinical Considerations and Public Health Explorations. | 2016 | AMA J Ethics | pmid:27002992 |
| Zhou T et al. | Determination of azithromycin residue in pork using a molecularly imprinted monolithic microcolumn coupled to liquid chromatography with tandem mass spectrometry. | 2016 | J Sep Sci | pmid:26854282 |
| Das MC et al. | Attenuation of Pseudomonas aeruginosa biofilm formation by Vitexin: A combinatorial study with azithromycin and gentamicin. | 2016 | Sci Rep | pmid:27000525 |
| Saleh A et al. | Comparison of adjunctive azithromycin and amoxicillin/metronidazole for patients with chronic periodontitis: preliminary randomized control trial. | 2016 | Aust Dent J | pmid:26836781 |
| Maeda M et al. | Study on rectal administration of azithromycin by suppository for pediatric use. | 2016 | Int J Clin Pharmacol Ther | pmid:26833461 |
| Jost C et al. | Susceptibility of enterohaemorrhagic Escherichia coli to azithromycin in France and analysis of resistance mechanisms. | 2016 | J. Antimicrob. Chemother. | pmid:26832755 |
| Demczuk W et al. | Genomic Epidemiology and Molecular Resistance Mechanisms of Azithromycin-Resistant Neisseria gonorrhoeae in Canada from 1997 to 2014. | 2016 | J. Clin. Microbiol. | pmid:26935729 |
| Mohotti JE et al. | A case of bilateral endogenous bacterial endophthalmitis from Streptococcus pneumoniae bacteraemia. | 2016 | Med. J. Aust. | pmid:26821111 |
| Trac MH et al. | Macrolide antibiotics and the risk of ventricular arrhythmia in older adults. | 2016 | CMAJ | pmid:26903359 |
| Topp E et al. | Reduced persistence of the macrolide antibiotics erythromycin, clarithromycin and azithromycin in agricultural soil following several years of exposure in the field. | 2016 | Sci. Total Environ. | pmid:27096634 |
| Li X et al. | Macrolides use and the risk of sudden cardiac death. | 2016 | Expert Rev Anti Infect Ther | pmid:27086751 |
| Arnold FW et al. | Macrolide Use and Neutrophil Function/Cytokine Levels in Hospitalized Patients with Community-Acquired Pneumonia: A Pilot Study. | 2016 | Lung | pmid:26553025 |
| Olszewska-Sosińska O et al. | Persistence of non-typeable Haemophilus Influenzae in the pharynx of children with adenotonsillar hypertrophy after treatment with azithromycin. | 2016 | Pathog Dis | pmid:26546328 |
| Wakiguchi H et al. | Multiple Renal and Splenic Lesions in Cat Scratch Disease. | 2016 | Jpn. J. Infect. Dis. | pmid:26567841 |
| So W et al. | Poor outcomes of empiric ceftriaxone ± azithromycin for community-acquired pneumonia caused by methicillin-susceptible Staphylococcus aureus. | 2016 | Intern Emerg Med | pmid:26531307 |
| Amantea D et al. | Azithromycin protects mice against ischemic stroke injury by promoting macrophage transition towards M2 phenotype. | 2016 | Exp. Neurol. | pmid:26518285 |
| Manavi K et al. | Comparison of doxycycline with azithromycin in treatment of pharyngeal chlamydia infection. | 2016 | Int J STD AIDS | pmid:26511655 |
| Williams KM et al. | Fluticasone, Azithromycin, and Montelukast Treatment for New-Onset Bronchiolitis Obliterans Syndrome after Hematopoietic Cell Transplantation. | 2016 | Biol. Blood Marrow Transplant. | pmid:26475726 |
| Fegan D et al. | Tropical leg ulcers in children: more than yaws. | 2016 | Trop Doct | pmid:26289420 |
| Kasten G et al. | Development of low density azithromycin-loaded polycaprolactone microparticles for pulmonary delivery. | 2016 | Drug Dev Ind Pharm | pmid:26289002 |
| Lee RA et al. | Evaluation of baseline corrected QT interval and azithromycin prescriptions in an academic medical center. | 2016 | J Hosp Med | pmid:26287278 |
| Kasten G et al. | Development of low density azithromycin-loaded polycaprolactone microparticles for pulmonary delivery. | 2016 | Drug Dev Ind Pharm | pmid:26266961 |
| Keenan JD et al. | Nasopharyngeal Pneumococcal Serotypes Before and After Mass Azithromycin Distributions for Trachoma. | 2016 | J Pediatric Infect Dis Soc | pmid:27199475 |
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| Wright H et al. | Evaluating Guideline-Recommended Antibiotic Practices for Childhood Respiratory Infections: Is It Time to Consider Case-Based Formats? | 2016 | Clin Pediatr (Phila) | pmid:25986442 |
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| Oliveira IS et al. | Evaluation of the improvement of quality of life with Azithromycin in the treatment of eosinophilic nasal polyposis. | 2016 Mar-Apr | Braz J Otorhinolaryngol | pmid:26601998 |
| Akoglu G et al. | Erlotinib-induced purpuric papulopustular eruption treated with pulsed azithromycin. | 2016 May-Jun | Indian J Pharmacol | pmid:27298507 |
| Diniz LM et al. | Bacillary angiomatosis with bone invasion. | 2016 Nov-Dec | An Bras Dermatol | pmid:28099606 |
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| Gaydos CA | Mycoplasma genitalium: Accurate Diagnosis Is Necessary for Adequate Treatment. | 2017 | J. Infect. Dis. | pmid:28838072 |
| Ribeiro M et al. | Azithromycin treatment is able to control the infection by two genotypes of Toxoplasma gondii in human trophoblast BeWo cells. | 2017 | Exp. Parasitol. | pmid:28803905 |
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| Wiesenfeld HC | Screening for Chlamydia trachomatis Infections in Women. | 2017 | N. Engl. J. Med. | pmid:28225683 |
| Shmarina G et al. | Steady-State Therapy with Azithromycin or Low-Dose Prednisolone in Paediatric Cystic Fibrosis Patients: Inflammatory Markers and Disease Progression. | 2017 | Int. Arch. Allergy Immunol. | pmid:28219060 |
| Ramappa M et al. | Successful Medical Management of Presumptive Pythium insidiosum Keratitis. | 2017 | Cornea | pmid:28207431 |
| González-Beiras C et al. | Yaws Osteoperiostitis Treated with Single-Dose Azithromycin. | 2017 | Am. J. Trop. Med. Hyg. | pmid:28193743 |
| Campanón-Toro MV et al. | Acute generalized exanthematous pustulosis (AGEP) induced by azithromycin. | 2017 | Contact Derm. | pmid:28497632 |
| Shastay A | The Absence of a Drug-Disease Interaction Alert Leads to a Child's Death. | 2017 | Home Healthc Now | pmid:28471797 |
| Papp JR et al. | Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA. | 2017 | Emerging Infect. Dis. | pmid:28418303 |
| Liu Y et al. | Azithromycin ameliorates airway remodeling via inhibiting airway epithelium apoptosis. | 2017 | Life Sci. | pmid:27916734 |
| Vandooren J et al. | Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study. | 2017 | PLoS ONE | pmid:28369077 |
| Valdés SO et al. | Cardiac Arrest in Pediatric Patients Receiving Azithromycin. | 2017 | J. Pediatr. | pmid:27912925 |
| Bojang E et al. | Short-term increase in prevalence of nasopharyngeal carriage of macrolide-resistant Staphylococcus aureus following mass drug administration with azithromycin for trachoma control. | 2017 | BMC Microbiol. | pmid:28351345 |
| Kong FY et al. | Pharmacokinetics of a single 1g dose of azithromycin in rectal tissue in men. | 2017 | PLoS ONE | pmid:28350806 |
| Bornstein M et al. | Factors Associated With Primary Care Physician Knowledge of the Recommended Regimen for Treating Gonorrhea. | 2017 | Sex Transm Dis | pmid:27898574 |
| Murphy TK et al. | A Double-Blind Randomized Placebo-Controlled Pilot Study of Azithromycin in Youth with Acute-Onset Obsessive-Compulsive Disorder. | 2017 | J Child Adolesc Psychopharmacol | pmid:28358599 |
| Eyre DW et al. | WGS to predict antibiotic MICs for Neisseria gonorrhoeae. | 2017 | J. Antimicrob. Chemother. | pmid:28333355 |
| Shan LS et al. | Effects of methylprednisolone or immunoglobulin when added to standard treatment with intravenous azithromycin for refractory Mycoplasma pneumoniae pneumonia in children. | 2017 | World J Pediatr | pmid:28130749 |
| Daimee UA et al. | A 77-year-old man with fever and night sweats. | 2017 | Eur. J. Intern. Med. | pmid:27765389 |
| Purssell A et al. | Azithromycin and Doxycycline Attenuation of Acanthamoeba Virulence in a Human Corneal Tissue Model. | 2017 | J. Infect. Dis. | pmid:27578848 |
| Romero L et al. | Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults. | 2017 | Cochrane Database Syst Rev | pmid:29226307 |
| Lusk MJ et al. | Cervicitis: a prospective observational study of empiric azithromycin treatment in women with cervicitis and non-specific cervicitis. | 2017 | Int J STD AIDS | pmid:26792283 |
| Marks M and Mabey D | Single-dose azithromycin to treat latent yaws. | 2017 | Lancet Glob Health | pmid:29107622 |
| Mitjà O et al. | Effectiveness of single-dose azithromycin to treat latent yaws: a longitudinal comparative cohort study. | 2017 | Lancet Glob Health | pmid:29107621 |
| Terkelsen D et al. | Multidrug-resistant infection with ceftriaxone resistance and intermediate resistance to azithromycin, Denmark, 2017. | 2017 | Euro Surveill. | pmid:29067905 |
| Halhal B et al. | Pertussis Outbreak Among Soldiers During Basic Training: The Need for Updated Protocols. | 2017 | Mil Med | pmid:28291499 |
| Çelik Payçu DG and Büyükbaba Boral Ö | [Effects of azithromycin and Chlorella vulgaris treatment on certain cytokine values and NK cell activity in an acute murine toxoplasmosis model]. | 2017 | Mikrobiyol Bul | pmid:28283010 |
| Garcia-Vidal C et al. | Levofloxacin versus azithromycin for treating legionella pneumonia: a propensity score analysis. | 2017 | Clin. Microbiol. Infect. | pmid:28267637 |
| Salman S et al. | Optimal Antimalarial Dose Regimens for Sulfadoxine-Pyrimethamine with or without Azithromycin in Pregnancy Based on Population Pharmacokinetic Modeling. | 2017 | Antimicrob. Agents Chemother. | pmid:28242669 |