| MeSH term | MeSH ID | Detail |
|---|---|---|
| Periodontitis | D010518 | 22 associated lipids |
| Gastrointestinal Diseases | D005767 | 20 associated lipids |
| Vomiting | D014839 | 21 associated lipids |
| Fever | D005334 | 35 associated lipids |
| Anaphylaxis | D000707 | 35 associated lipids |
| Pregnancy Complications, Infectious | D011251 | 11 associated lipids |
| Toxoplasmosis | D014123 | 9 associated lipids |
| Toxoplasmosis, Congenital | D014125 | 2 associated lipids |
| Otitis Media with Effusion | D010034 | 9 associated lipids |
| Shock, Septic | D012772 | 11 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hook EW et al. | Azithromycin compared with penicillin G benzathine for treatment of incubating syphilis. | 1999 | Ann. Intern. Med. | pmid:10498560 |
| Butler T et al. | Treatment of typhoid fever with azithromycin versus chloramphenicol in a randomized multicentre trial in India. | 1999 | J. Antimicrob. Chemother. | pmid:10473232 |
| Melnichouk S et al. | Evaluation of lansoprazole (an H+/K+-ATPase inhibitor) and azithromycin (an antibiotic) for control of gastric ulceration in swine during periods of feed deprivation. | 1999 | Can. J. Vet. Res. | pmid:10534003 |
| Howell MR et al. | Control of Chlamydia trachomatis infections in female army recruits: cost-effective screening and treatment in training cohorts to prevent pelvic inflammatory disease. | 1999 | Sex Transm Dis | pmid:10534206 |
| Mabey D and Bailey R | Eradication of trachoma worldwide. | 1999 | Br J Ophthalmol | pmid:10535853 |
| Muhlestein JB | Animal models of chlamydia and atherosclerosis. | 1999 | Am. Heart J. | pmid:10539862 |
| Gupta S | Chlamydia pneumoniae, monocyte activation, and azithromycin in coronary heart disease. | 1999 | Am. Heart J. | pmid:10539869 |
| Dunne M | WIZARD and the design of trials for secondary prevention of atherosclerosis with antibiotics. | 1999 | Am. Heart J. | pmid:10539870 |
| Grayston JT | Design of future intervention studies for Chlamydia pneumoniae in atherosclerosis. | 1999 | Am. Heart J. | pmid:10539875 |
| Goldstein EJ et al. | Activities of telithromycin (HMR 3647, RU 66647) compared to those of erythromycin, azithromycin, clarithromycin, roxithromycin, and other antimicrobial agents against unusual anaerobes. | 1999 | Antimicrob. Agents Chemother. | pmid:10543769 |
| Whitty CJ et al. | Impact of community-based mass treatment for trachoma with oral azithromycin on general morbidity in Gambian children. | 1999 | Pediatr. Infect. Dis. J. | pmid:10571428 |
| Tan HH and Chan RK | An open label comparative study of azithromycin and doxycycline in the treatment of non-gonococcal urethritis in males and Chlamydia trachomatis cervicitis in female sex workers in an STD clinic in Singapore. | 1999 | Singapore Med J | pmid:10572491 |
| Shanks GD et al. | Single dose of azithromycin or three-day course of ciprofloxacin as therapy for epidemic dysentery in Kenya. Acute Dysentery Study Group. | 1999 | Clin. Infect. Dis. | pmid:10589921 |
| Sendi PP et al. | Cost-effectiveness of azithromycin for preventing Mycobacterium avium complex infection in HIV-positive patients in the era of highly active antiretroviral therapy. The Swiss HIV Cohort Study. | 1999 | J. Antimicrob. Chemother. | pmid:10590283 |
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| Girgis NI et al. | Azithromycin versus ciprofloxacin for treatment of uncomplicated typhoid fever in a randomized trial in Egypt that included patients with multidrug resistance. | 1999 | Antimicrob. Agents Chemother. | pmid:10348767 |
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| Preheim LC et al. | Ethanol feeding does not affect the efficacy or pharmacokinetics of azithromycin, trovafloxacin, or ceftriaxone in a rat model of pneumococcal pneumonia. | 1999 | Alcohol. Clin. Exp. Res. | pmid:10371404 |
| Drugs for sexually transmitted infections. | 1999 | Med Lett Drugs Ther | pmid:10906932 | |
| Burgess DS et al. | A time-kill evaluation of clarithromycin and azithromycin against two extracellular pathogens and the development of resistance. | 1999 | Ann Pharmacother | pmid:10630825 |
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| Breitschwerdt EB et al. | Efficacy of doxycycline, azithromycin, or trovafloxacin for treatment of experimental Rocky Mountain spotted fever in dogs. | 1999 | Antimicrob. Agents Chemother. | pmid:10103185 |
| Laine L et al. | Once-daily therapy for H. pylori infection: a randomized comparison of four regimens. | 1999 | Am. J. Gastroenterol. | pmid:10201465 |
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| Cinti S et al. | Killing of Mycobacterium avium by neutrophils and monocytes from AIDS patients treated with recombinant granulocyte-macrophage colony-stimulating factor. | 1999 | J. Infect. Dis. | pmid:10353887 |
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| Klapan I et al. | Azithromycin versus amoxicillin/clavulanate in the treatment of acute sinusitis. | 1999 Jan-Feb | Am J Otolaryngol | pmid:9950107 |
| Gorenek L et al. | The diagnosis and treatment of Clostridium difficile in antibiotic-associated diarrhea. | 1999 Jan-Feb | Hepatogastroenterology | pmid:10228818 |
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| Sawhney N | MAC prophylaxis in the era of polypharmacy. | 1999 May-Jun | WMJ | pmid:10414219 |
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| Paavonen J and Eggert-Kruse W | Chlamydia trachomatis: impact on human reproduction. | 1999 Sep-Oct | Hum. Reprod. Update | pmid:10582782 |
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| Infection fighters. MAC prevention takes a holiday. | 2000 | TreatmentUpdate | pmid:12132450 | |
| Ress BD and Gross EM | Irreversible sensorineural hearing loss as a result of azithromycin ototoxicity. A case report. | 2000 | Ann. Otol. Rhinol. Laryngol. | pmid:10778901 |
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| Brieland JK et al. | Efficacy of SCH27899 in an animal model of Legionnaires' disease using immunocompromised A/J mice. | 2000 | Antimicrob. Agents Chemother. | pmid:10770771 |
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| Dunne MW | Rationale and design of a secondary prevention trial of antibiotic use in patients after myocardial infarction: the WIZARD (weekly intervention with zithromax [azithromycin] for atherosclerosis and its related disorders) trial. | 2000 | J. Infect. Dis. | pmid:10839762 |
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| Grayston JT | Secondary prevention antibiotic treatment trials for coronary artery disease. | 2000 | Circulation | pmid:11023925 |
| Muhlestein JB et al. | Randomized secondary prevention trial of azithromycin in patients with coronary artery disease: primary clinical results of the ACADEMIC study. | 2000 | Circulation | pmid:11023928 |
| Bharat V and Mohanty B | Bleeding complication during coumarin therapy due to amiodarone and azithromycin. | 2000 | J Assoc Physicians India | pmid:11273517 |
| Gulati R et al. | Comparative bioavailability of two formulations of azithromycin. | 2000 | J Assoc Physicians India | pmid:11273540 |