Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Cremer J et al. | Azithromycin versus cefaclor in the treatment of pediatric patients with acute group A beta-hemolytic streptococcal tonsillopharyngitis. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9707305 |
Blandizzi C et al. | Gastric mucosal distribution and clinical efficacy of azithromycin in patients with Helicobacter pylori related gastritis. | 1998 | J. Antimicrob. Chemother. | pmid:9700531 |
Soepandi P et al. | The pattern of micro-organisms and the efficacy of new macrolide in acute lower respiratory tract infections. | 1998 | Respirology | pmid:9692520 |
Turcinov T and Pepeljnjak S | Azithromycin potency determination: optimal conditions for microbiological diffusion method assay. | 1998 | J Pharm Biomed Anal | pmid:9682177 |
Zaremba CD | Comment: could acetaminophen have played a role in a possible azithromycin-warfarin interaction? | 1998 Jul-Aug | Ann Pharmacother | pmid:9681108 |
Rapp RP | Pharmacokinetics and pharmacodynamics of intravenous and oral azithromycin: enhanced tissue activity and minimal drug interactions. | 1998 Jul-Aug | Ann Pharmacother | pmid:9681095 |
Wawer MJ et al. | A randomized, community trial of intensive sexually transmitted disease control for AIDS prevention, Rakai, Uganda. | 1998 | AIDS | pmid:9677171 |
Carbon C | Pharmacodynamics of macrolides, azalides, and streptogramins: effect on extracellular pathogens. | 1998 | Clin. Infect. Dis. | pmid:9675445 |
Dooley DP | Revisiting doxycycline. | 1998 | Arch. Intern. Med. | pmid:9665360 |
Nash MM and Zaltzman JS | Efficacy of azithromycin in the treatment of cyclosporine-induced gingival hyperplasia in renal transplant recipients. | 1998 | Transplantation | pmid:9665078 |
Vcev A et al. | Omeprazole, azithromycin and either amoxycillin or metronidazole in eradication of Helicobacter pylori in duodenal ulcer patients. | 1998 | Aliment. Pharmacol. Ther. | pmid:9663725 |
Klein JO | Clarithromycin and azithromycin. | 1998 | Pediatr. Infect. Dis. J. | pmid:9655546 |
Bass JW et al. | Prospective randomized double blind placebo-controlled evaluation of azithromycin for treatment of cat-scratch disease. | 1998 | Pediatr. Infect. Dis. J. | pmid:9655532 |
Griffith DE et al. | Initial (6-month) results of three-times-weekly azithromycin in treatment regimens for Mycobacterium avium complex lung disease in human immunodeficiency virus-negative patients. | 1998 | J. Infect. Dis. | pmid:9652431 |
[6th München AIDS-Days. Azithromycin in HIV-associated opportunistic infections]. | 1998 | Internist (Berl) | pmid:9648000 | |
Karpov OI et al. | [Comparative trial of 3-day azithromycin versus 10-day coamoxilav course efficacy in acute sinusitis]. | 1998 | Ter. Arkh. | pmid:9644751 |
Altschuler EL | Azithromycin, the multidrug-resistant protein, and cystic fibrosis. | 1998 | Lancet | pmid:9643772 |
Motohiro T et al. | [Clinical study on azithromycin in 10% fine granules and 100mg capsules in the field of pediatrics]. | 1997 | Jpn J Antibiot | pmid:9634360 |
Bowden FJ and Savage J | Azithromycin for the treatment of donovanosis. | 1998 | Sex Transm Infect | pmid:9634320 |
Roblin PM and Hammerschlag MR | In vitro activity of a new ketolide antibiotic, HMR 3647, against Chlamydia pneumoniae. | 1998 | Antimicrob. Agents Chemother. | pmid:9624507 |