Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Chronic Disease D002908 7 associated lipids
Tick Infestations D013984 4 associated lipids
Retinitis D012173 4 associated lipids
Common Variable Immunodeficiency D017074 4 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Skin Diseases, Vesiculobullous D012872 5 associated lipids
Chlamydia Infections D002690 7 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Whooping Cough D014917 6 associated lipids
Urethritis D014526 9 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Yaws D015001 4 associated lipids
Syphilis, Latent D013592 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Vertigo D014717 4 associated lipids
Pelvic Pain D017699 7 associated lipids
Pneumonia, Pneumococcal D011018 3 associated lipids
Leishmaniasis, Cutaneous D016773 6 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Exanthema D005076 11 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Chen QF and Zhang YW [Clinical effect of Saccharomyces boulardii powder combined with azithromycin sequential therapy in treatment of children with diarrhea secondary to Mycoplasma pneumoniae pneumonia]. 2018 Zhongguo Dang Dai Er Ke Za Zhi pmid:29429459
Horner P et al. Which azithromycin regimen should be used for treating ? A meta-analysis. 2018 Sex Transm Infect pmid:28717050
Latif AS et al. Antimicrobial susceptibility in isolates from five sentinel surveillance sites in Zimbabwe, 2015-2016. 2018 Sex Transm Infect pmid:28476914
Mulugeta A et al. Coverage, social mobilization and challenges of mass Zithromax administration campaign in South and South East zones of Tigray, Northern Ethiopia: A cross sectional study. 2018 PLoS Negl Trop Dis pmid:29481558
Atkin PA and Simms ML Orofacial granulomatosis: an unsuccessful response to weekly azithromycin pulse therapy. 2018 Oral Surg Oral Med Oral Pathol Oral Radiol pmid:29477603
Liu YH et al. Antimicrobial susceptibilities and molecular typing of neisseria gonorrhoeae isolates at a medical centre in Taiwan, 2001-2013 with an emphasis on high rate of azithromycin resistance among the isolates. 2018 Int. J. Antimicrob. Agents pmid:29477549
Mannelli VK et al. . 2018 BMJ Case Rep pmid:29472421
de Oliveira Alves A et al. Young Boy With Roughening in the Inner Eyelids. 2018 Ann Emerg Med pmid:29458812
Astale T et al. Population-based coverage survey results following the mass drug administration of azithromycin for the treatment of trachoma in Amhara, Ethiopia. 2018 PLoS Negl Trop Dis pmid:29451881
Bogdan M et al. In vitro effect of subminimal inhibitory concentrations of antibiotics on the biofilm formation ability of Acinetobacter baumannii clinical isolates. 2018 J Chemother pmid:28956494
Wang R et al. IncA/C plasmids conferring high azithromycin resistance in vibrio cholerae. 2018 Int. J. Antimicrob. Agents pmid:28919196
Ersoy B et al. The anti-inflammatory effects of erythromycin, clarithromycin, azithromycin and roxithromycin on histamine-induced otitis media with effusion in guinea pigs. 2018 J Laryngol Otol pmid:29888693
Gibson PG How does azithromycin improve asthma exacerbations? - Author's reply. 2018 Lancet pmid:29323652
Sanchez Garcia D et al. Cellular accumulation and lipid binding of perfluorinated alkylated substances (PFASs) - A comparison with lysosomotropic drugs. 2018 Chem. Biol. Interact. pmid:29248446
Lederhandler MH et al. Severe Oral Mucositis: A Rare Adverse Event of Pembrolizumab. 2018 J Drugs Dermatol pmid:30005106
Valor C and Huber K Atypical presentation of cat scratch disease: Parinaud's oculoglandular syndrome with facial nerve paresis. 2018 BMJ Case Rep pmid:29982178
Lanz J and Lautenschlager S [CME Dermatology 16/Answer: Fever, Pustules and Joint Pain as Vacation Mementoes]. 2018 Praxis (Bern 1994) pmid:29921188
Kalua K et al. One round of azithromycin MDA adequate to interrupt transmission in districts with prevalence of trachomatous inflammation-follicular of 5.0-9.9%: Evidence from Malawi. 2018 PLoS Negl Trop Dis pmid:29897902
Smotrys M et al. Babesiosis as a cause of false-positive HIV serology. 2018 BMJ Case Rep pmid:29884713
Nüesch-Inderbinen M et al. Genetic characterization of Shiga toxin producing Escherichia coli belonging to the emerging hybrid pathotype O80:H2 isolated from humans 2010-2017 in Switzerland. 2018 Int. J. Med. Microbiol. pmid:29884331