Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Syphilis D013587 6 associated lipids
Hearing Disorders D006311 10 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Precursor Cell Lymphoblastic Leukemia-Lymphoma D054198 10 associated lipids
Uterine Cervicitis D002575 3 associated lipids
Neutropenia D009503 15 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Urticaria D014581 13 associated lipids
Escherichia coli Infections D004927 17 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Motohiro T et al. [Clinical study on azithromycin in 10% fine granules and 100mg capsules in the field of pediatrics]. 1997 Jpn J Antibiot pmid:9634360
Ramos JT et al. Cryptosporidium in patients infected with human immunodeficiency virus: azithromycin revisited. 1997 J. Pediatr. pmid:9202631
Nachbaur D et al. Cryptosporidiosis after CD34-selected autologous peripheral blood stem cell transplantation (PBSCT). Treatment with paromomycin, azithromycin and recombinant human interleukin-2. 1997 Bone Marrow Transplant. pmid:9208124
Luke DR and Foulds G Disposition of oral azithromycin in humans. 1997 Clin. Pharmacol. Ther. pmid:9209246
Herrera-Insúa I et al. Synergistic effect of azithromycin on the phagocytic killing of Staphylococcus aureus by human polymorphonuclear leukocytes. 1997 Eur. J. Clin. Microbiol. Infect. Dis. pmid:9063667
Pascual A et al. Azithromycin uptake by tissue cultured epithelial cells. 1997 J. Antimicrob. Chemother. pmid:9069561
Khan WA et al. Treatment of shigellosis: V. Comparison of azithromycin and ciprofloxacin. A double-blind, randomized, controlled trial. 1997 Ann. Intern. Med. pmid:9139555
Yasin RM et al. Comparison of E-test with agar dilution methods in testing susceptibility of N. gonorrhoeae to azithromycin. 1997 Sex Transm Dis pmid:9153733
Pacifico L and Chiesa C Efficacy of three-day azithromycin vs. ten-day penicillin V in the treatment of streptococcal pharyngitis. 1997 Pediatr. Infect. Dis. J. pmid:9154566
Fernandez-Obregon AC Azithromycin for the treatment of acne. 1997 Int. J. Dermatol. pmid:9159021
Nightingale CH Pharmacokinetics and pharmacodynamics of newer macrolides. 1997 Pediatr. Infect. Dis. J. pmid:9109156
Block SL Causative pathogens, antibiotic resistance and therapeutic considerations in acute otitis media. 1997 Pediatr. Infect. Dis. J. pmid:9109158
Mosby JA Treating acute bronchitis with azithromycin. 1997 Am Fam Physician pmid:9054218
Blanshard C et al. Pilot studies of azithromycin, letrazuril and paromomycin in the treatment of cryptosporidiosis. 1997 Int J STD AIDS pmid:9061412
Hoepelman IM et al. A short (3-day) course of azithromycin tablets versus a 10-day course of amoxycillin-clavulanic acid (co-amoxiclav) in the treatment of adults with lower respiratory tract infections and effects on long-term outcome. 1997 Int. J. Antimicrob. Agents pmid:9552709
Dudle G et al. [Meningitis after acute Borrelia burgdorferi infection in HIV infection]. 1997 Dtsch. Med. Wochenschr. pmid:9378035
Dautzenberg B Rationale for the prevention of disseminated Mycobacterium avium-intracellulare complex disease. 1997 Drugs pmid:9358194
Cohn DL Prevention strategies for Mycobacterium avium-intracellulare complex (MAC) infection. A review of recent studies in patients with AIDS. 1997 Drugs pmid:9358195
Marone P et al. Rapid drug susceptibility of Mycobacterium avium complex using a fluorescence quenching method. 1997 J Chemother pmid:9269603
Gruber F et al. Comparative trial of azithromycin and ciprofloxacin in the treatment of gonorrhea. 1997 J Chemother pmid:9269606
Jepras RI et al. Rapid assessment of antibiotic effects on Escherichia coli by bis-(1,3-dibutylbarbituric acid) trimethine oxonol and flow cytometry. 1997 Antimicrob. Agents Chemother. pmid:9303401
Rodríguez-Bano J et al. [Penetration of azithromycin into human neutrophils: effect of hydrogen peroxide production]. 1997 Enferm. Infecc. Microbiol. Clin. pmid:9312278
Gupta S et al. Elevated Chlamydia pneumoniae antibodies, cardiovascular events, and azithromycin in male survivors of myocardial infarction. 1997 Circulation pmid:9244203
Vazifeh D et al. Cellular accumulation of the new ketolide RU 64004 by human neutrophils: comparison with that of azithromycin and roxithromycin. 1997 Antimicrob. Agents Chemother. pmid:9333032
Nilius AM et al. Variability in susceptibilities of Haemophilus influenzae to clarithromycin and azithromycin due to medium pH. 1997 J. Clin. Microbiol. pmid:9163435
Malizia T et al. Periodontal tissue disposition of azithromycin. 1997 J. Periodontol. pmid:9444596
Nguyen MH et al. Potentiation of antifungal activity of amphotericin B by azithromycin against Aspergillus species. 1997 Eur. J. Clin. Microbiol. Infect. Dis. pmid:9447909
Jones RN and Biedenbach DJ Antimicrobial activity of RU-66647, a new ketolide. 1997 Jan-Feb Diagn. Microbiol. Infect. Dis. pmid:9127099
Pollak PT and Slayter KL Reduced serum theophylline concentrations after discontinuation of azithromycin: evidence for an unusual interaction. 1997 Jul-Aug Pharmacotherapy pmid:9250566
Grunden JW and Fisher KA Lovastatin-induced rhabdomyolysis possibly associated with clarithromycin and azithromycin. 1997 Jul-Aug Ann Pharmacother pmid:9220046
Tartaglione T Treatment of nontuberculous mycobacterial infections: role of clarithromycin and azithromycin. 1997 Jul-Aug Clin Ther pmid:9377608
Shaio MF and Yang KD Response of babesiosis to a combined regimen of quinine and azithromycin. 1997 Mar-Apr Trans. R. Soc. Trop. Med. Hyg. pmid:9196774
Stevens RC et al. Pharmacokinetics of azithromycin after single- and multiple-doses in children. 1997 Sep-Oct Pharmacotherapy pmid:9324176
Destache CJ et al. Microbiologic effect of bovine cerebrospinal fluid and azithromycin against Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae. 1997 Sep-Oct Pharmacotherapy pmid:9324186
Lauvau DV and Verbist L An open, multicentre, comparative study of the efficacy and safety of azithromycin and co-amoxiclav in the treatment of upper and lower respiratory tract infections in children. The Paediatric Azithromycin Study Group. 1997 Sep-Oct J. Int. Med. Res. pmid:9364291
Bianchi A et al. Kinetics of Chlamydia trachomatis clearance in patients with azithromycin, as assessed by first void urine testing by PCR and transcription-mediated amplification. 1998 Sex Transm Dis pmid:9713917
Karpov OI et al. [Comparative trial of 3-day azithromycin versus 10-day coamoxilav course efficacy in acute sinusitis]. 1998 Ter. Arkh. pmid:9644751
[6th München AIDS-Days. Azithromycin in HIV-associated opportunistic infections]. 1998 Internist (Berl) pmid:9648000
Denis A and Agouridas C Synthesis of 6-O-methyl-azithromycin and its ketolide analogue via Beckmann rearrangement of 9(E)-6-O-methyl-erythromycin oxime. 1998 Bioorg. Med. Chem. Lett. pmid:9873555
Gascón A et al. Cryptosporidiosis in a haemodialysis patient with depressed CD4+ T cell count: successful treatment with azithromycin. 1998 Nephrol. Dial. Transplant. pmid:9829506
Hoppe JE and Bryskier A In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to two ketolides (HMR 3004 and HMR 3647), four macrolides (azithromycin, clarithromycin, erythromycin A, and roxithromycin), and two ansamycins (rifampin and rifapentine). 1998 Antimicrob. Agents Chemother. pmid:9559823
Fuentes F et al. Postanitbiotic and sub-MIC effects of azithromycin and isepamicin against Staphylococcus aureus and Escherichia coli. 1998 Antimicrob. Agents Chemother. pmid:9527796
Kashuba AD and Amsden GW Bronchopulmonary pharmacokinetics of clarithromycin and azithromycin. 1998 Antimicrob. Agents Chemother. pmid:9527816
Champney WS and Burdine R Macrolide antibiotic inhibition of translation and 50S ribosomal subunit assembly in methicillin-resistant Staphylococcus aureus cells. 1998 Microb. Drug Resist. pmid:9818968
Thalhammer F et al. Azithromycin-related toxic effects of digitoxin. 1998 Br J Clin Pharmacol pmid:9489601
Goldstein EJ et al. Activities of HMR 3004 (RU 64004) and HMR 3647 (RU 66647) compared to those of erythromycin, azithromycin, clarithromycin, roxithromycin, and eight other antimicrobial agents against unusual aerobic and anaerobic human and animal bite pathogens isolated from skin and soft tissue infections in humans. 1998 Antimicrob. Agents Chemother. pmid:9593139
Turcinov T and Pepeljnjak S Azithromycin potency determination: optimal conditions for microbiological diffusion method assay. 1998 J Pharm Biomed Anal pmid:9682177
Lacy MK et al. Comparison of bactericidal activity after multidose administration of clarithromycin, azithromycin, and ceruroxime axetil against Streptococcus pneumoniae. 1998 Int. J. Antimicrob. Agents pmid:9916901
Fera MT et al. Bactericidal activity of lansoprazole and three macrolides against Helicobacter pylori strains tested by the time-kill kinetic method. 1998 Int. J. Antimicrob. Agents pmid:9916902
Carbon C Pharmacodynamics of macrolides, azalides, and streptogramins: effect on extracellular pathogens. 1998 Clin. Infect. Dis. pmid:9675445