| MeSH term | MeSH ID | Detail |
|---|---|---|
| Syphilis | D013587 | 6 associated lipids |
| Hearing Disorders | D006311 | 10 associated lipids |
| Encephalomyelitis, Autoimmune, Experimental | D004681 | 26 associated lipids |
| Infant, Newborn, Diseases | D007232 | 9 associated lipids |
| Precursor Cell Lymphoblastic Leukemia-Lymphoma | D054198 | 10 associated lipids |
| Uterine Cervicitis | D002575 | 3 associated lipids |
| Neutropenia | D009503 | 15 associated lipids |
| Lung Diseases, Obstructive | D008173 | 10 associated lipids |
| Urticaria | D014581 | 13 associated lipids |
| Escherichia coli Infections | D004927 | 17 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Harris JA et al. | Safety and efficacy of azithromycin in the treatment of community-acquired pneumonia in children. | 1998 | Pediatr. Infect. Dis. J. | pmid:9802626 |
| Adair CD et al. | Chlamydia in pregnancy: a randomized trial of azithromycin and erythromycin. | 1998 | Obstet Gynecol | pmid:9469269 |
| GarcÃa Callejo FJ et al. | [Comparison of azithromycin, amoxicillin/clavulanic acid and cefaclor in the treatment of acute ENT infections]. | 1998 | Acta Otorrinolaringol Esp | pmid:9707742 |
| Kober MB and Mason BA | Colonization of the female genital tract by resistant Ureaplasma urealyticum treated successfully with azithromycin. | 1998 | Clin. Infect. Dis. | pmid:9709898 |
| Langtry HD and Balfour JA | Azithromycin. A review of its use in paediatric infectious diseases. | 1998 | Drugs | pmid:9711451 |
| Bianchi A et al. | Kinetics of Chlamydia trachomatis clearance in patients with azithromycin, as assessed by first void urine testing by PCR and transcription-mediated amplification. | 1998 | Sex Transm Dis | pmid:9713917 |
| Karpov OI et al. | [Comparative trial of 3-day azithromycin versus 10-day coamoxilav course efficacy in acute sinusitis]. | 1998 | Ter. Arkh. | pmid:9644751 |
| [6th München AIDS-Days. Azithromycin in HIV-associated opportunistic infections]. | 1998 | Internist (Berl) | pmid:9648000 | |
| Griffith DE et al. | Initial (6-month) results of three-times-weekly azithromycin in treatment regimens for Mycobacterium avium complex lung disease in human immunodeficiency virus-negative patients. | 1998 | J. Infect. Dis. | pmid:9652431 |
| Haye R et al. | Azithromycin versus placebo in acute infectious rhinitis with clinical symptoms but without radiological signs of maxillary sinusitis. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9721958 |
| Wirnsberger GH et al. | Effect of antibiotic treatment with azithromycin on cyclosporine A-induced gingival hyperplasia among renal transplant recipients. | 1998 | Transplant. Proc. | pmid:9723411 |
| Blandizzi C et al. | Gastric mucosal distribution and clinical efficacy of azithromycin in patients with Helicobacter pylori related gastritis. | 1998 | J. Antimicrob. Chemother. | pmid:9700531 |
| Denis A and Agouridas C | Synthesis of 6-O-methyl-azithromycin and its ketolide analogue via Beckmann rearrangement of 9(E)-6-O-methyl-erythromycin oxime. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9873555 |
| den Hollander JG et al. | Comparison of pharmacodynamics of azithromycin and erythromycin in vitro and in vivo. | 1998 | Antimicrob. Agents Chemother. | pmid:9527789 |
| Chey WD et al. | Low- versus high-dose azithromycin triple therapy for Helicobacter pylori infection. | 1998 | Aliment. Pharmacol. Ther. | pmid:9882036 |
| Trevisani L et al. | Evaluation of a new ultrashort triple therapy for Helicobacter pylori disease. | 1998 | Aliment. Pharmacol. Ther. | pmid:9882037 |
| Gascón A et al. | Cryptosporidiosis in a haemodialysis patient with depressed CD4+ T cell count: successful treatment with azithromycin. | 1998 | Nephrol. Dial. Transplant. | pmid:9829506 |
| Sackoff J et al. | Prophylaxis for opportunistic infections among HIV-infected patients receiving medical care. | 1998 | J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. | pmid:9833748 |
| Hogan PA and Sheehan DJ | Macrolide susceptibility and beta-lactamase production among haemophilus influenzae isolates in the United States, 1996-1997. | 1998 | Antimicrob. Agents Chemother. | pmid:9835536 |
| Mortensen JE et al. | In vitro activity of oral antimicrobial agents against clinical isolates of Pasteurella multocida. | 1998 | Diagn. Microbiol. Infect. Dis. | pmid:9554176 |
| Hoppe JE and Bryskier A | In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to two ketolides (HMR 3004 and HMR 3647), four macrolides (azithromycin, clarithromycin, erythromycin A, and roxithromycin), and two ansamycins (rifampin and rifapentine). | 1998 | Antimicrob. Agents Chemother. | pmid:9559823 |
| Clancy CJ and Nguyen MH | The combination of amphotericin B and azithromycin as a potential new therapeutic approach to fusariosis. | 1998 | J. Antimicrob. Chemother. | pmid:9511049 |
| Oldfield EC et al. | Once weekly azithromycin therapy for prevention of Mycobacterium avium complex infection in patients with AIDS: a randomized, double-blind, placebo-controlled multicenter trial. | 1998 | Clin. Infect. Dis. | pmid:9524832 |
| Fuentes F et al. | Postanitbiotic and sub-MIC effects of azithromycin and isepamicin against Staphylococcus aureus and Escherichia coli. | 1998 | Antimicrob. Agents Chemother. | pmid:9527796 |
| Kashuba AD and Amsden GW | Bronchopulmonary pharmacokinetics of clarithromycin and azithromycin. | 1998 | Antimicrob. Agents Chemother. | pmid:9527816 |
| Socan M | Treatment of atypical pneumonia with azithromycin: comparison of a 5-day and a 3-day course. | 1998 | J Chemother | pmid:9531077 |
| Muhlestein JB et al. | Infection with Chlamydia pneumoniae accelerates the development of atherosclerosis and treatment with azithromycin prevents it in a rabbit model. | 1998 | Circulation | pmid:9495296 |
| Woldtvedt BR et al. | Possible increased anticoagulation effect of warfarin induced by azithromycin. | 1998 | Ann Pharmacother | pmid:9496419 |
| Champney WS and Burdine R | Macrolide antibiotic inhibition of translation and 50S ribosomal subunit assembly in methicillin-resistant Staphylococcus aureus cells. | 1998 | Microb. Drug Resist. | pmid:9818968 |
| Seelis RE and Dohmen W | [Short-term (6 days) eradication of Helicobacter pylori infection in the practice of a health insurance physician]. | 1998 | Dtsch. Med. Wochenschr. | pmid:9487294 |
| Thalhammer F et al. | Azithromycin-related toxic effects of digitoxin. | 1998 | Br J Clin Pharmacol | pmid:9489601 |
| Wawer MJ et al. | A randomized, community trial of intensive sexually transmitted disease control for AIDS prevention, Rakai, Uganda. | 1998 | AIDS | pmid:9677171 |
| Goldstein EJ et al. | Activities of HMR 3004 (RU 64004) and HMR 3647 (RU 66647) compared to those of erythromycin, azithromycin, clarithromycin, roxithromycin, and eight other antimicrobial agents against unusual aerobic and anaerobic human and animal bite pathogens isolated from skin and soft tissue infections in humans. | 1998 | Antimicrob. Agents Chemother. | pmid:9593139 |
| Spangler SK et al. | Postantibiotic effect and postantibiotic sub-MIC effect of levofloxacin compared to those of ofloxacin, ciprofloxacin, erythromycin, azithromycin, and clarithromycin against 20 pneumococci. | 1998 | Antimicrob. Agents Chemother. | pmid:9593160 |
| Turcinov T and Pepeljnjak S | Azithromycin potency determination: optimal conditions for microbiological diffusion method assay. | 1998 | J Pharm Biomed Anal | pmid:9682177 |
| Pankuch GA et al. | In vitro selection of resistance to four beta-lactams and azithromycin in Streptococcus pneumoniae. | 1998 | Antimicrob. Agents Chemother. | pmid:9797225 |
| Dagan R et al. | Dynamics of pneumococcal nasopharyngeal colonization during the first days of antibiotic treatment in pediatric patients. | 1998 | Pediatr. Infect. Dis. J. | pmid:9802628 |
| Roblin PM and Hammerschlag MR | In vitro activity of a new ketolide antibiotic, HMR 3647, against Chlamydia pneumoniae. | 1998 | Antimicrob. Agents Chemother. | pmid:9624507 |
| Can antibiotics prevent heart disease? | 1998 | Harv Heart Lett | pmid:9619136 | |
| Bass JW et al. | Prospective randomized double blind placebo-controlled evaluation of azithromycin for treatment of cat-scratch disease. | 1998 | Pediatr. Infect. Dis. J. | pmid:9655532 |
| Gruber F et al. | Azithromycin compared with minocycline in the treatment of acne comedonica and papulo-pustulosa. | 1998 | J Chemother | pmid:9876055 |
| Négrel AD and Mariotti SP | WHO alliance for the global elimination of blinding trachoma and the potential use of azithromycin. | 1998 | Int. J. Antimicrob. Agents | pmid:9916898 |
| Lacy MK et al. | Comparison of bactericidal activity after multidose administration of clarithromycin, azithromycin, and ceruroxime axetil against Streptococcus pneumoniae. | 1998 | Int. J. Antimicrob. Agents | pmid:9916901 |
| Fera MT et al. | Bactericidal activity of lansoprazole and three macrolides against Helicobacter pylori strains tested by the time-kill kinetic method. | 1998 | Int. J. Antimicrob. Agents | pmid:9916902 |
| Jakob-Sölder B et al. | Treatment of pediatric patients with acute group A beta-hemolytic streptococcal tonsillopharyngitis. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9923529 |
| Rothova A et al. | Azithromycin for ocular toxoplasmosis. | 1998 | Br J Ophthalmol | pmid:9924338 |
| Apseloff G et al. | Comparison of azithromycin and clarithromycin in their interactions with rifabutin in healthy volunteers. | 1998 | J Clin Pharmacol | pmid:9753212 |
| Shih CM and Wang CC | Ability of azithromycin in combination with quinine for the elimination of babesial infection in humans. | 1998 | Am. J. Trop. Med. Hyg. | pmid:9790419 |
| Carbon C | Pharmacodynamics of macrolides, azalides, and streptogramins: effect on extracellular pathogens. | 1998 | Clin. Infect. Dis. | pmid:9675445 |
| Greenblatt DJ et al. | Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences. | 1998 | Clin. Pharmacol. Ther. | pmid:9757151 |