Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Trismus D014313 1 associated lipids
Tracheobronchomalacia D055089 1 associated lipids
Pneumocystis Infections D016720 1 associated lipids
Corneal Endothelial Cell Loss D055954 1 associated lipids
Male Urogenital Diseases D052801 1 associated lipids
Trichiasis D058457 1 associated lipids
Reproductive Tract Infections D060737 1 associated lipids
Frontal Sinusitis D015522 1 associated lipids
Asymptomatic Infections D058345 1 associated lipids
Hyper-IgM Immunodeficiency Syndrome D053306 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
See S Is azithromycin monotherapy as efficacious as cefuroxime plus erythromycin for the treatment of community-acquired pneumonia in hospitalized patients? 2000 J Fam Pract pmid:11052155
Renz CL and Ashraf T Comment: cost-effectiveness of macrolides in lower respiratory tract infections. 2000 Ann Pharmacother pmid:11054992
Boccazzi A et al. Short course therapy with cefitbuten versus azithromycin in pediatric streptococcal pharyngitis. 2000 Pediatr. Infect. Dis. J. pmid:11055597
Bayoumi AM and Redelmeier DA Decision analysis with cumulative prospect theory. 2000 Oct-Dec Med Decis Making pmid:11059473
Sader H and Del'Alamo L Etest compared to broth microdilution: discrepant results when testing macrolides against Streptococcus pneumoniae indicate a need for better clinical and serum level/MIC correlation. 2000 Braz J Infect Dis pmid:11063559
Frenck RW et al. Azithromycin versus ceftriaxone for the treatment of uncomplicated typhoid fever in children. 2000 Clin. Infect. Dis. pmid:11073741
Dunne M et al. A randomized, double-blind trial comparing azithromycin and clarithromycin in the treatment of disseminated Mycobacterium avium infection in patients with human immunodeficiency virus. 2000 Clin. Infect. Dis. pmid:11073759
Krause PJ et al. Atovaquone and azithromycin for the treatment of babesiosis. 2000 N. Engl. J. Med. pmid:11078770
Macaigne G et al. [Acute pseudoangiocholitic hepatitis probably induced by azithromycin]. 2000 Gastroenterol. Clin. Biol. pmid:11084438
Alvarez MP et al. [Pharmacovigilance study of azithromycin tablets (500 mg) in the treatment of adult patients with respiratory tract infections]. 2000 Rev Esp Quimioter pmid:11086281
Gandhi R et al. Validated LC method for in-vitro analysis of azithromycin using electrochemical detection. 2000 J Pharm Biomed Anal pmid:11095310
Bowman RJ et al. Operational comparison of single-dose azithromycin and topical tetracycline for trachoma. 2000 Invest. Ophthalmol. Vis. Sci. pmid:11095598
Nagai K et al. In vitro development of resistance to ceftriaxone, cefprozil and azithromycin in Streptococcus pneumoniae. 2000 J. Antimicrob. Chemother. pmid:11102409
Waterer GW et al. Fatal pneumococcal pneumonia attributed to macrolide resistance and azithromycin monotherapy. 2000 Chest pmid:11115489
Esposito S and Ascione T Short-course treatment for acute tonsillopharyngitis. 2000 Int. J. Antimicrob. Agents pmid:11118866
Rothstein NM et al. Effect of azithromycin on murine arteriosclerosis exacerbated by Chlamydia pneumoniae. 2001 J. Infect. Dis. pmid:11120929
Bermudez LE et al. Activity of moxifloxacin by itself and in combination with ethambutol, rifabutin, and azithromycin in vitro and in vivo against Mycobacterium avium. 2001 Antimicrob. Agents Chemother. pmid:11120969
Calabrese C et al. Pantoprazole, azithromycin and tinidazole: short duration triple therapy for eradication of Helicobacter pylori infection. 2000 Aliment. Pharmacol. Ther. pmid:11121909
DeAbate CA et al. The safety and efficacy of short course (5-day) moxifloxacin vs. azithromycin in the treatment of patients with acute exacerbation of chronic bronchitis. 2000 Respir Med pmid:11127487
Fuchs PC et al. Influence of variations in test methods on susceptibility of Haemophilus influenzae to ampicillin, azithromycin, clarithromycin, and telithromycin. 2001 J. Clin. Microbiol. pmid:11136745
Fonck K et al. A randomized, placebo-controlled trial of monthly azithromycin prophylaxis to prevent sexually transmitted infections and HIV-1 in Kenyan sex workers: study design and baseline findings. 2000 Int J STD AIDS pmid:11138916
Schilling F and Wagner AD [Azithromycin: an anti-inflammatory effect in chronic recurrent multifocal osteomyelitis? A preliminary report]. 2000 Z Rheumatol pmid:11142932
Powers JL et al. Comparison of the palatability of the oral suspension of cefdinir vs. amoxicillin/clavulanate potassium, cefprozil and azithromycin in pediatric patients. 2000 Pediatr. Infect. Dis. J. pmid:11144401
Vallejo C et al. Resolution of cyclosporine-induced gingival hyperplasia resistant to azithromycin by switching to tacrolimus. 2001 Haematologica pmid:11146586
Amsden GW and Gray CL Serum and WBC pharmacokinetics of 1500 mg of azithromycin when given either as a single dose or over a 3 day period in healthy volunteers. 2001 J. Antimicrob. Chemother. pmid:11152432
Giacometti A et al. Activity of buforin II alone and in combination with azithromycin and minocycline against Cryptosporidium parvum in cell culture. 2001 J. Antimicrob. Chemother. pmid:11152438
Skerk V et al. Duration of clinical symptoms in female patients with acute urethral syndrome caused by Ureaplasma urealyticum treated with azithromycin or doxycycline. 2000 J Chemother pmid:11154040
Gieffers J et al. Chlamydia pneumoniae infection in circulating human monocytes is refractory to antibiotic treatment. 2001 Circulation pmid:11157684
Putnam SD et al. Pharyngeal colonization prevalence rates for Streptococcus pyogenes and Streptococcus pneumoniae in a respiratory chemoprophylaxis intervention study using azithromycin. 2000 Clin. Microbiol. Infect. pmid:11168029
Simsir A et al. Rhodococcus equi and cytomegalovirus pneumonia in a renal transplant patient: diagnosis by fine-needle aspiration biopsy. 2001 Diagn. Cytopathol. pmid:11169894
Solera J et al. Azithromycin and gentamicin therapy for the treatment of humans with brucellosis. 2001 Clin. Infect. Dis. pmid:11170962
Gerber MA and Tanz RR New approaches to the treatment of group A streptococcal pharyngitis. 2001 Curr. Opin. Pediatr. pmid:11176244
Conrad DA Treatment of cat-scratch disease. 2001 Curr. Opin. Pediatr. pmid:11176245
From the Centers for Disease Control and Prevention. Fluoroquinolone resistance in Neisseria gonorrhoeae, Hawaii, 1999, and decreased susceptibility to azithromycin in N. gonorrhoeae, Missouri, 1999. 2000 JAMA pmid:11183745
West S The red eye. 2000 N. Engl. J. Med. pmid:11184764
McNabb J et al. Comparison of azithromycin leukocyte disposition in healthy volunteers and volunteers with AIDS. 2000 Int. J. Antimicrob. Agents pmid:11185411
Amsden GW et al. A study of the pharmacokinetics of azithromycin and nelfinavir when coadministered in healthy volunteers. 2000 J Clin Pharmacol pmid:11185676
Mamikoglu B and Mamikoglu O Irreversible sensorineural hearing loss as a result of azithromycin ototoxicity. A case report. 2001 Ann. Otol. Rhinol. Laryngol. pmid:11201801
Khera M Azithromycin. 2000 Conn Med pmid:11210327
Amsden G et al. Lack of an effect of azithromycin on the disposition of zidovudine and dideoxyinosine in HIV-infected patients. 2001 J Clin Pharmacol pmid:11210404
Bogdanov MB and Chernen'kaia TV [Microbiological evaluation of antibiotics for empirical therapy of community-acquired infections of the lower respiratory tract]. 2000 Antibiot. Khimioter. pmid:11212394
Budanov SV [Azithromycin (sumamed)--basic properties and therapy of community-acquired pneumonia]. 2000 Antibiot. Khimioter. pmid:11212397
Solomon AW et al. Pilot study of the use of community volunteers to distribute azithromycin for trachoma control in Ghana. 2001 Bull. World Health Organ. pmid:11217675
Bregani ER et al. Azithromycin in the treatment of Plasmodium falciparum gametocytes. Preliminary observation. 2000 Panminerva Med pmid:11218625
Mizen L The activity of antibiotics against Legionella pneumophila: in vitro and in vivo studies. 2001 J. Antimicrob. Chemother. pmid:11222573
Weiss LM et al. The treatment of babesiosis. 2001 N. Engl. J. Med. pmid:11236789
Ranque S The treatment of babesiosis. 2001 N. Engl. J. Med. pmid:11236790
Dagan R et al. Antibiotic treatment in acute Otitis Media promotes superinfection with resistant Streptococcus pneumoniae carried before initiation of treatment. 2001 J. Infect. Dis. pmid:11237804
Hyde TB et al. Azithromycin prophylaxis during a hospital outbreak of Mycoplasma pneumoniae pneumonia. 2001 J. Infect. Dis. pmid:11237807
Cascaval RI and Lancaster DJ Hypersensitivity syndrome associated with azithromycin. 2001 Am. J. Med. pmid:11247598