Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Tracheobronchomalacia D055089 1 associated lipids
Trismus D014313 1 associated lipids
Pneumocystis Infections D016720 1 associated lipids
Trichiasis D058457 1 associated lipids
Reproductive Tract Infections D060737 1 associated lipids
Corneal Endothelial Cell Loss D055954 1 associated lipids
Male Urogenital Diseases D052801 1 associated lipids
Frontal Sinusitis D015522 1 associated lipids
Hyper-IgM Immunodeficiency Syndrome D053306 1 associated lipids
Paratyphoid Fever D010284 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Currier J Progress report: prophylaxis and therapy for MAC. 1996 AIDS Clin Care pmid:11363599
Old drug approved for MAC prevention. 1996 AIDS Alert pmid:11363659
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Marco M Opportunistic infections in Vancouver. 1996 GMHC Treat Issues pmid:11363841
Azithromycin effective in preventing MAC. 1996 AIDS Alert pmid:11363857
D'Amico R ICAAC update on opportunistic infections. 1996 Nov-Dec Posit Aware pmid:11363974
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Syphilis elimination seen as good HIV prevention. 1998 AIDS Alert pmid:11365457
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Edelstein PH et al. In vitro activity of gemifloxacin (SB-265805, LB20304a) against Legionella pneumophila and its pharmacokinetics in guinea pigs with L. pneumophila pneumonia. 2001 Antimicrob. Agents Chemother. pmid:11451675
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Gómez J et al. [Prospective, comparative study (1994-1998) of the influence of short-term prophylactic treatment with azithromycin on patients with advanced COPD]. 2000 Rev Esp Quimioter pmid:11498704
Tyteca D et al. Azithromycin, a lysosomotropic antibiotic, impairs fluid-phase pinocytosis in cultured fibroblasts. 2001 Eur. J. Cell Biol. pmid:11499789
Dillon JA et al. Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from three Caribbean countries: Trinidad, Guyana, and St. Vincent. 2001 Sex Transm Dis pmid:11518867
Dillon JA et al. Reduced susceptibility to azithromycin and high percentages of penicillin and tetracycline resistance in Neisseria gonorrhoeae isolates from Manaus, Brazil, 1998. 2001 Sex Transm Dis pmid:11518869
Damianov L et al. [Treatment of genital chlamydia infections with Sumamed]. 2001 Akush Ginekol (Sofiia) pmid:11519320
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Gray GC et al. Randomized, placebo-controlled clinical trial of oral azithromycin prophylaxis against respiratory infections in a high-risk, young adult population. 2001 Clin. Infect. Dis. pmid:11528569
Schlegel L et al. In vitro activity of midecamycin diacetate, a 16-membered macrolide, against Streptococcus pyogenes isolated in France, 1995-1999. 2001 Clin. Microbiol. Infect. pmid:11531981
Urbano F and Urbano P Azithromycin in healthy adults? 2001 Clin. Microbiol. Infect. pmid:11531993
Miyazaki S et al. Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice. 2001 J. Antimicrob. Chemother. pmid:11533011
Milkovic-Kraus S and Kanceljak-Macan B Occupational airborne allergic contact dermatitis from azithromycin. 2001 Contact Derm. pmid:11553158
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Rubinstein E Comparative safety of the different macrolides. 2001 Int. J. Antimicrob. Agents pmid:11574199
Malizia T et al. Interaction between piroxicam and azithromycin during distribution to human periodontal tissues. 2001 J. Periodontol. pmid:11577945