Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Abnormalities, Drug-Induced D000014 10 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Abscess D000038 13 associated lipids
Achondroplasia D000130 1 associated lipids
Acinetobacter Infections D000151 4 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Airway Obstruction D000402 13 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Tribble D et al. Efficacy of azithromycin for typhoid fever. 1995 Clin. Infect. Dis. pmid:8645805
Tabbara KF et al. Single-dose azithromycin in the treatment of trachoma. A randomized, controlled study. 1996 Ophthalmology pmid:8637698
Luft BJ et al. Azithromycin compared with amoxicillin in the treatment of erythema migrans. A double-blind, randomized, controlled trial. 1996 Ann. Intern. Med. pmid:8610947
Di Mario F et al. Azithromycin for the cure of Helicobacter pylori infection. 1996 Am. J. Gastroenterol. pmid:8607490
Bertoni G et al. Triple therapy with azithromycin, omeprazole, and amoxicillin is highly effective in the eradication of Helicobacter pylori: a controlled trial versus omeprazole plus amoxicillin. 1996 Am. J. Gastroenterol. pmid:8607489
Bohte R et al. Levels of azithromycin and alpha-1 acid glycoprotein in serum in patients with community-acquired pneumonia. 1995 Antimicrob. Agents Chemother. pmid:8593024
Nash KA and Inderlied CB Genetic basis of macrolide resistance in Mycobacterium avium isolated from patients with disseminated disease. 1995 Antimicrob. Agents Chemother. pmid:8592991
Domingo S et al. Comparative activity of azithromycin and doxycycline against Brucella spp. infection in mice. 1995 J. Antimicrob. Chemother. pmid:8591939
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Kuzman I et al. Azithromycin for treatment of community acquired pneumonia caused by Legionella pneumophila: a retrospective study. 1995 Scand. J. Infect. Dis. pmid:8588143
Strickman D et al. In vitro effectiveness of azithromycin against doxycycline-resistant and -susceptible strains of Rickettsia tsutsugamushi, etiologic agent of scrub typhus. 1995 Antimicrob. Agents Chemother. pmid:8585717
Principi N Multicentre comparative study of the efficacy and safety of azithromycin compared with amoxicillin/clavulanic acid in the treatment of paediatric patients with otitis media. 1995 Eur. J. Clin. Microbiol. Infect. Dis. pmid:8565983
Amin NM and Breadon G An open-label, noncomparative study to evaluate the efficacy, safety, and tolerability of azithromycin in the treatment of patients with acute sinusitis. 1995 Jul-Aug Clin Ther pmid:8565033
Martin DH et al. Comparison of azithromycin and ceftriaxone for the treatment of chancroid. 1995 Clin. Infect. Dis. pmid:8562752
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Amsden GW Macrolides versus azalides: a drug interaction update. 1995 Ann Pharmacother pmid:8547740
Oh YK et al. Formulation and efficacy of liposome-encapsulated antibiotics for therapy of intracellular Mycobacterium avium infection. 1995 Antimicrob. Agents Chemother. pmid:8540724
Tissi L et al. In vivo efficacy of azithromycin in treatment of systemic infection and septic arthritis induced by type IV group B Streptococcus strains in mice: comparative study with erythromycin and penicillin G. 1995 Antimicrob. Agents Chemother. pmid:8540695
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Perronne C [Azithromycin and Mycobacterium avium infection]. 1995 Pathol. Biol. pmid:8539084
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Gehanno P [Use of azithromycin in ORL]. 1995 Pathol. Biol. pmid:8539077
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Felstead S Azithromycin drug interactions. 1995 Pathol. Biol. pmid:8539073
Singlas E [Clinical pharmacokinetics of azithromycin]. 1995 Pathol. Biol. pmid:8539072
Bergogne-Bérézin E [Azithromycin: tissue pharmacology]. 1995 Pathol. Biol. pmid:8539071
[Special issue devoted to azithromycin]. 1995 Pathol. Biol. pmid:8539068
Carbon C [Azithromycin: from macrolides to azalides]. 1995 Pathol. Biol. pmid:8539067
van Rijsoort-Vos JH et al. In-vitro activity of a new quinolone (CP-99,219) compared with ciprofloxacin, pefloxacin, azithromycin and penicillin against Neisseria gonorrhoeae. 1995 J. Antimicrob. Chemother. pmid:8537268
Kieserman SP et al. Streptococcal pharyngitis: alternative treatments. 1995 Ear Nose Throat J pmid:8536567
Erdogru T et al. The treatment of non-gonococcal urethritis with single dose oral azithromycin. 1995 Sep-Oct J. Int. Med. Res. pmid:8529783
Kuschner RA et al. Use of azithromycin for the treatment of Campylobacter enteritis in travelers to Thailand, an area where ciprofloxacin resistance is prevalent. 1995 Clin. Infect. Dis. pmid:8527539
Genç M et al. An economic evaluation of screening for Chlamydia trachomatis in adolescent males. 1993 JAMA pmid:8411572
Workowski KA et al. Azithromycin in chlamydial urethritis. 1993 JAMA pmid:8411548
Kobrehel G et al. 9a,11-cyclic carbamates of 15-membered azalides. 1993 J. Antibiot. pmid:8407586
Narcio Reyes LE et al. [Efficacy and safety of azithromycin in the treatment of female genital Chlamydia trachomatis infections]. 1993 Ginecol Obstet Mex pmid:8406112
Fortner JH et al. Tapetal effect of an azalide antibiotic following oral administration in beagle dogs. 1993 Fundam Appl Toxicol pmid:8405779
Goldman MP and Longworth DL The role of azithromycin and clarithromycin in clinical practice. 1993 Sep-Oct Cleve Clin J Med pmid:8403355
Guerra LG et al. Rapid response of AIDS-related bacillary angiomatosis to azithromycin. 1993 Clin. Infect. Dis. pmid:8399879
Mansoor GA et al. Azithromycin-induced acute interstitial nephritis. 1993 Ann. Intern. Med. pmid:8395778
Gingras BA and Jensen JB Antimalarial activity of azithromycin and erythromycin against Plasmodium berghei. 1993 Am. J. Trop. Med. Hyg. pmid:8394660
Vargas SL et al. Azithromycin for treatment of severe Cryptosporidium diarrhea in two children with cancer. 1993 J. Pediatr. pmid:8391567
Rodewald LE and Pichichero ME Compliance with antibiotic therapy: a comparison of deuterium oxide tracer, urine bioassay, bottle weights, and parental reports. 1993 J. Pediatr. pmid:8391566