Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Tick Bites D064927 1 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Reproductive Tract Infections D060737 1 associated lipids
Granulomatous Mastitis D058890 1 associated lipids
Trichiasis D058457 1 associated lipids
Asymptomatic Infections D058345 1 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Neglected Diseases D058069 3 associated lipids
Corneal Endothelial Cell Loss D055954 1 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Principi N Multicentre comparative study of the efficacy and safety of azithromycin compared with amoxicillin/clavulanic acid in the treatment of paediatric patients with otitis media. 1995 Eur. J. Clin. Microbiol. Infect. Dis. pmid:8565983
Lo KK et al. An open non-comparative pilot study with azithromycin in the treatment of non-gonococcal urethritis in the sexually transmitted disease clinics in Hong Kong. 1995 Ann. Acad. Med. Singap. pmid:8849186
Singlas E [Clinical pharmacokinetics of azithromycin]. 1995 Pathol. Biol. pmid:8539072
Felstead S Azithromycin drug interactions. 1995 Pathol. Biol. pmid:8539073
Modaï J [Azithromycin: clinical assessment]. 1995 Pathol. Biol. pmid:8539076
Gehanno P [Use of azithromycin in ORL]. 1995 Pathol. Biol. pmid:8539077
Leophonte P [Azithromycin and bronchopulmonary infections]. 1995 Pathol. Biol. pmid:8539078
Micoud M and Pépin LF [Azithromycin and genital infections]. 1995 Pathol. Biol. pmid:8539079
Coulaud JP [Azithromycin: new orientations]. 1995 Pathol. Biol. pmid:8539080
Reinert P [Effects of azithromycin on the virulence of Pseudomonas aeruginosa]. 1995 Pathol. Biol. pmid:8539081
Tomazic J et al. Ex vivo effect of azithromycin in human leukocyte bactericidal functions. 1995 Antimicrob. Agents Chemother. pmid:7486947
Zuckerman JM and Kaye KM The newer macrolides. Azithromycin and clarithromycin. 1995 Infect. Dis. Clin. North Am. pmid:7490441
Kobayashi H et al. [Study on azithromycin in treatment of diffuse panbronchiolitis]. 1995 Kansenshogaku Zasshi pmid:7616016
Ljutić D and Rumboldt Z Possible interaction between azithromycin and cyclosporin: a case report. 1995 Nephron pmid:7617103
Nilsen OG Pharmacokinetics of macrolides. Comparison of plasma, tissue and free concentrations with special reference to roxithromycin. 1995 Infection pmid:7782117
Anderson SL et al. Prophylaxis of Plasmodium falciparum malaria with azithromycin administered to volunteers. 1995 Ann. Intern. Med. pmid:7574195
Backman JT et al. Azithromycin does not increase plasma concentrations of oral midazolam. 1995 Int J Clin Pharmacol Ther pmid:7582388
Harris S et al. Azithromycin and terfenadine: lack of drug interaction. 1995 Clin. Pharmacol. Ther. pmid:7554704
Pascual A et al. Factors affecting the intracellular accumulation and activity of azithromycin. 1995 J. Antimicrob. Chemother. pmid:7768786
Beghi G et al. Efficacy and tolerability of azithromycin versus amoxicillin/clavulanic acid in acute purulent exacerbation of chronic bronchitis. 1995 J Chemother pmid:7666122