Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Tick Bites D064927 1 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Reproductive Tract Infections D060737 1 associated lipids
Granulomatous Mastitis D058890 1 associated lipids
Trichiasis D058457 1 associated lipids
Asymptomatic Infections D058345 1 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Neglected Diseases D058069 3 associated lipids
Corneal Endothelial Cell Loss D055954 1 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Fortner JH et al. Tapetal effect of an azalide antibiotic following oral administration in beagle dogs. 1993 Fundam Appl Toxicol pmid:8405779
Narcio Reyes LE et al. [Efficacy and safety of azithromycin in the treatment of female genital Chlamydia trachomatis infections]. 1993 Ginecol Obstet Mex pmid:8406112
Donowitz GR and Earnhardt KI Azithromycin inhibition of intracellular Legionella micdadei. 1993 Antimicrob. Agents Chemother. pmid:8285604
Hammerschlag MR et al. Single dose of azithromycin for the treatment of genital chlamydial infections in adolescents. 1993 J. Pediatr. pmid:8388950
Kobrehel G et al. 9a,11-cyclic carbamates of 15-membered azalides. 1993 J. Antibiot. pmid:8407586
Blais J et al. Inhibition of Toxoplasma gondii protein synthesis by azithromycin. 1993 Antimicrob. Agents Chemother. pmid:8215287
Dever LL et al. Comparative in vitro activities of clarithromycin, azithromycin, and erythromycin against Borrelia burgdorferi. 1993 Antimicrob. Agents Chemother. pmid:8215288
Fass RJ Erythromycin, clarithromycin, and azithromycin: use of frequency distribution curves, scattergrams, and regression analyses to compare in vitro activities and describe cross-resistance. 1993 Antimicrob. Agents Chemother. pmid:8257127
Gomberg MA and MashkilleÄ­son AL [Use of azithromycin in long existing urogenital chlamydia infections and its association with primary syphilis]. 1993 Antibiot. Khimioter. pmid:8060178
Sidorenko SV [Azithromycin--an antibiotic of the azalide group]. 1993 Antibiot. Khimioter. pmid:8060181
Lopatkin NA et al. [Use of azithromycin ("Sumamded") in the treatment of infectious-inflammatory diseases of the lower urinary tract and male genitalia]. 1993 Antibiot. Khimioter. pmid:8060189
Saba J et al. Pyrimethamine plus azithromycin for treatment of acute toxoplasmic encephalitis in patients with AIDS. 1993 Eur. J. Clin. Microbiol. Infect. Dis. pmid:8112357
Meyer AP et al. Uptake of azithromycin by human monocytes and enhanced intracellular antibacterial activity against Staphylococcus aureus. 1993 Antimicrob. Agents Chemother. pmid:8285612
Lalak NJ and Morris DL Azithromycin clinical pharmacokinetics. 1993 Clin Pharmacokinet pmid:8287632
Saverino D et al. Plasmid loss from gram-negative bacteria exposed to subinhibitory concentrations of beta-lactam drugs and azithromycin. 1993 New Microbiol. pmid:8264424
Pajukanta R In vitro antimicrobial susceptibility of Porphyromonas gingivalis to azithromycin, a novel macrolide. 1993 Oral Microbiol. Immunol. pmid:8265209
Rodewald LE and Pichichero ME Compliance with antibiotic therapy: a comparison of deuterium oxide tracer, urine bioassay, bottle weights, and parental reports. 1993 J. Pediatr. pmid:8391566
Vargas SL et al. Azithromycin for treatment of severe Cryptosporidium diarrhea in two children with cancer. 1993 J. Pediatr. pmid:8391567
Workowski KA et al. Azithromycin in chlamydial urethritis. 1993 JAMA pmid:8411548
Genç M et al. An economic evaluation of screening for Chlamydia trachomatis in adolescent males. 1993 JAMA pmid:8411572