| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tick Bites | D064927 | 1 associated lipids |
| Chlamydial Pneumonia | D061387 | 2 associated lipids |
| Reproductive Tract Infections | D060737 | 1 associated lipids |
| Granulomatous Mastitis | D058890 | 1 associated lipids |
| Trichiasis | D058457 | 1 associated lipids |
| Asymptomatic Infections | D058345 | 1 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Neglected Diseases | D058069 | 3 associated lipids |
| Corneal Endothelial Cell Loss | D055954 | 1 associated lipids |
| Multiple Pulmonary Nodules | D055613 | 2 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Vranes J et al. | Influence of subinhibitory concentrations of ceftazidime, ciprofloxacin and azithromycin on the morphology and adherence of P-fimbriated escherichia coli. | 1996 | J Chemother | pmid:8873829 |
| Laing RB et al. | Clinical features, outcome and survival from cerebral toxoplasmosis in Edinburgh AIDS patients. | 1996 | Int J STD AIDS | pmid:8876356 |
| Berg-Candolfi M and Candolfi E | Depression of the N-demethylation of erythromycin, azithromycin, clarithromycin and clindamycin in murine Toxoplasma infection. | 1996 | Int. J. Parasitol. | pmid:9024879 |
| Tansey MJ and Moe JB | Severe neutropenia and prophylactic doses of rifabutin. | 1996 | Lancet | pmid:8950911 |
| Sefton AM et al. | Azithromycin in the treatment of periodontal disease. Effect on microbial flora. | 1996 | J. Clin. Periodontol. | pmid:8951627 |
| Griffith DE et al. | Varying dosages of rifabutin affect white blood cell and platelet counts in human immunodeficiency virus--negative patients who are receiving multidrug regimens for pulmonary Mycobacterium avium complex disease. | 1996 | Clin. Infect. Dis. | pmid:8953085 |
| Clearance to market azithromycin as prevention for a common OI in advanced AIDS. | 1996 | AIDS Patient Care STDS | pmid:11361535 | |
| Prophylactic antibiotic receives speedy FDA approval to reduce MAC disease in advanced HIV. | 1996 | AIDS Patient Care STDS | pmid:11361569 | |
| Azithromycin and OIs. | 1996 | AIDS Patient Care STDS | pmid:11361699 | |
| Segreti J et al. | In vitro activity of macrolides against intracellular Legionella pneumophila. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8902407 |
| Tabbara KF et al. | Single-dose azithromycin in the treatment of trachoma. A randomized, controlled study. | 1996 | Ophthalmology | pmid:8637698 |
| Bertoni G et al. | Triple therapy with azithromycin, omeprazole, and amoxicillin is highly effective in the eradication of Helicobacter pylori: a controlled trial versus omeprazole plus amoxicillin. | 1996 | Am. J. Gastroenterol. | pmid:8607489 |
| Hulten K et al. | In-vitro activity of azithromycin in against intracellular Helicobacter pylori. | 1996 | J. Antimicrob. Chemother. | pmid:9182105 |
| Di Mario F et al. | Azithromycin for the cure of Helicobacter pylori infection. | 1996 | Am. J. Gastroenterol. | pmid:8607490 |
| Na-Bangchang K et al. | Activity of artemether-azithromycin versus artemether-doxycycline in the treatment of multiple drug resistant falciparum malaria. | 1996 | Southeast Asian J. Trop. Med. Public Health | pmid:9185262 |
| Laurent K | Efficacy, safety and tolerability of azithromycin versus roxithromycin in the treatment of acute lower respiratory tract infections. | 1996 | J. Antimicrob. Chemother. | pmid:8818852 |
| Montero L | A comparative study of the efficacy, safety and tolerability of azithromycin and cefaclor in the treatment of children with acute skin and/or soft tissue infections. | 1996 | J. Antimicrob. Chemother. | pmid:8818853 |
| Nahata M | Drug interactions with azithromycin and the macrolides: an overview. | 1996 | J. Antimicrob. Chemother. | pmid:8818854 |
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| Carbon C et al. | Economic analysis of antibiotic regimens used in the treatment pharyngitis: a prospective comparison of azithromycin versus roxithromycin. | 1996 | J. Antimicrob. Chemother. | pmid:8818856 |
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| Domingo S and Gamazo C | Inadequate azithromycin activity against Brucella melitensis in mice with acute or chronic infections. | 1996 | J Chemother | pmid:8835110 |
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| Dupont C et al. | Microbiological findings about pulmonary cryptosporidiosis in two AIDS patients. | 1996 | J. Clin. Microbiol. | pmid:8748314 |
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| Jackson MA et al. | Breakthrough sepsis in macrolide-resistant pneumococcal infection. | 1996 | Pediatr. Infect. Dis. J. | pmid:8933560 |
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| Caselli M et al. | A comparative trial of short term therapy with omeprazole plus either amoxycillin or azithromycin for Helicobacter pylori eradication. | 1996 | J. Antimicrob. Chemother. | pmid:8722557 |
| Falagas ME and Klempner MS | Babesiosis in patients with AIDS: a chronic infection presenting as fever of unknown origin. | 1996 | Clin. Infect. Dis. | pmid:8722936 |
| Murphy GS et al. | Ciprofloxacin- and azithromycin-resistant Campylobacter causing traveler's diarrhea in U.S. troops deployed to Thailand in 1994. | 1996 | Clin. Infect. Dis. | pmid:8722958 |
| Scorneaux B et al. | Effect of recombinant human gamma interferon on intracellular activities of antibiotics against Listeria monocytogenes in the human macrophage cell line THP-1. | 1996 | Antimicrob. Agents Chemother. | pmid:8723471 |
| Havlir DV et al. | Prophylaxis against disseminated Mycobacterium avium complex with weekly azithromycin, daily rifabutin, or both. California Collaborative Treatment Group. | 1996 | N. Engl. J. Med. | pmid:8676932 |
| Tursi A et al. | The use of azithromycin in short-term low-dose triple therapies for Helicobacter pylori infection. | 1996 | Am. J. Gastroenterol. | pmid:8677967 |
| Thorpe EM et al. | Chlamydial cervicitis and urethritis: single dose treatment compared with doxycycline for seven days in community based practises. | 1996 | Genitourin Med | pmid:8698374 |
| Wilton LV et al. | A comparison of ciprofloxacin, norfloxacin, ofloxacin, azithromycin and cefixime examined by observational cohort studies. | 1996 | Br J Clin Pharmacol | pmid:8730972 |
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| Hayle R et al. | Efficacy and safety of azithromycin versus phenoxymethylpenicillin in the treatment of acute maxillary sinusitis. | 1996 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8997555 |
| Adhikari P et al. | Evaluation of safety and efficacy of azithromycin in lower respiratory tract infections (LRTI) | 1996 | Indian J Med Sci | pmid:9057364 |
| Thylefors B | Trachoma--new opportunities to tackle an old problem. | 1996 | Br J Ophthalmol | pmid:9059262 |
| Three new studies expand understanding of MAC therapy. | 1996 | Am J Health Syst Pharm | pmid:8899122 | |
| Evans LA et al. | Predicting injection site muscle damage. III: Evaluation of intramuscular formulations in the L6 cell model. | 1996 | Pharm. Res. | pmid:8899856 |
| O'Doherty B | Azithromycin versus penicillin V in the treatment of paediatric patients with acute streptococcal pharyngitis/tonsillitis. Paediatric Azithromycin Study Group. | 1996 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8922571 |
| Cellesi C et al. | Susceptibility of macrolide and beta-lactam antibiotics of Streptococcus pyogenes strains isolated over a four-year period in central Italy. | 1996 | J Chemother | pmid:8808714 |
| Welsh L et al. | In vitro activities of azithromycin, clarithromycin, erythromycin, and tetracycline against 13 strains of Chlamydia pneumoniae. | 1996 | Antimicrob. Agents Chemother. | pmid:8787907 |
| Mehaffey PC et al. | Evaluation of in vitro spectra of activity of azithromycin, clarithromycin, and erythromycin tested against strains of Neisseria gonorrhoeae by reference agar dilution, disk diffusion, and Etest methods. | 1996 | J. Clin. Microbiol. | pmid:8789046 |
| Keysary A et al. | The in-vitro anti-rickettsial activity of macrolides. | 1996 | J. Antimicrob. Chemother. | pmid:8937968 |
| Mein J et al. | Donovanosis: sequelae of severe disease and successful azithromycin treatment. | 1996 | Int J STD AIDS | pmid:8940677 |
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| Watt B et al. | Comparative activity of azithromycin against clinical isolates of mycobacteria. | 1996 | J. Antimicrob. Chemother. | pmid:8889727 |
| Mashkilleyson AL et al. | Treatment of syphilis with azithromycin. | 1996 | Int J STD AIDS | pmid:8652720 |
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| Amsden GW | Erythromycin, clarithromycin, and azithromycin: are the differences real? | 1996 Jan-Feb | Clin Ther | pmid:8851453 |
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| Fontán PA et al. | Haemophilus influenzae type b exoproducts induce chemotaxis and macrolide antibiotic release by human polymorphonuclear leukocytes. | 1996 Jan-Feb | Chemotherapy | pmid:8751269 |
| Ehret JM et al. | A clinical isolate of Neisseria gonorrhoeae with in vitro resistance to erythromycin and decreased susceptibility to azithromycin. | 1996 Jul-Aug | Sex Transm Dis | pmid:8836018 |
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| Carlin EM and Barton SE | Azithromycin as the first-line treatment of non-gonococcal urethritis (NGU): a study of follow-up rates, contact attendance and patients' treatment preference. | 1996 May-Jun | Int J STD AIDS | pmid:8799780 |
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| Vranes J | Effect of subinhibitory concentrations of ceftazidime, ciprofloxacin, and azithromycin on the hemagglutination and adherence of uropathogenic Escherichia coli strains. | 1996 May-Jun | Chemotherapy | pmid:8983884 |
| Ichimiya T et al. | The influence of azithromycin on the biofilm formation of Pseudomonas aeruginosa in vitro. | 1996 May-Jun | Chemotherapy | pmid:8983885 |
| Galova K et al. | Multicenter randomized study of two once daily regimens in the initial management of community-acquired respiratory tract infections in 163 children: azithromycin versus ceftibuten. | 1996 May-Jun | Chemotherapy | pmid:8983893 |
| Burke SM | Azithromycin: only once a day. | 1996 May-Jun | MCN Am J Matern Child Nurs | pmid:8857402 |
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| Wendel TD | 1-day azithromycin was as effective as 7-day doxycycline for nongonococcal urethritis syndrome in men. | 1996 Nov-Dec | ACP J. Club | pmid:8912627 |
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| Fernandez-Obregon AC | Azithromycin for the treatment of acne. | 1997 | Int. J. Dermatol. | pmid:9159021 |
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| Dawson CR et al. | A comparison of oral azithromycin with topical oxytetracycline/polymyxin for the treatment of trachoma in children. | 1997 | Clin. Infect. Dis. | pmid:9114186 |
| Caselli M et al. | Short-term low-dose triple therapy with azithromycin, metronidazole and lansoprazole appears highly effective for the eradication of Helicobacter pylori. | 1997 | Eur J Gastroenterol Hepatol | pmid:9031898 |
| Arévalo Morles C et al. | Donovanosis: treatment with azithromycin. | 1997 | Int J STD AIDS | pmid:9043983 |
| Hoepelman IM et al. | A short (3-day) course of azithromycin tablets versus a 10-day course of amoxycillin-clavulanic acid (co-amoxiclav) in the treatment of adults with lower respiratory tract infections and effects on long-term outcome. | 1997 | Int. J. Antimicrob. Agents | pmid:9552709 |
| Gupta S et al. | Elevated Chlamydia pneumoniae antibodies, cardiovascular events, and azithromycin in male survivors of myocardial infarction. | 1997 | Circulation | pmid:9244203 |
| Vazifeh D et al. | Cellular accumulation of the new ketolide RU 64004 by human neutrophils: comparison with that of azithromycin and roxithromycin. | 1997 | Antimicrob. Agents Chemother. | pmid:9333032 |
| Nilius AM et al. | Variability in susceptibilities of Haemophilus influenzae to clarithromycin and azithromycin due to medium pH. | 1997 | J. Clin. Microbiol. | pmid:9163435 |
| Rajyaguru JM and Muszynski MJ | Enhancement of Burkholderia cepacia antimicrobial susceptibility by cationic compounds. | 1997 | J. Antimicrob. Chemother. | pmid:9338485 |
| Odenholt I et al. | Studies of the killing kinetics of benzylpenicillin, cefuroxime, azithromycin, and sparfloxacin on bacteria in the postantibiotic phase. | 1997 | Antimicrob. Agents Chemother. | pmid:9371360 |